AU534945B2 – Anti-hypertensive agents
– Google Patents
AU534945B2 – Anti-hypertensive agents
– Google Patents
Anti-hypertensive agents
Info
Publication number
AU534945B2
AU534945B2
AU59227/80A
AU5922780A
AU534945B2
AU 534945 B2
AU534945 B2
AU 534945B2
AU 59227/80 A
AU59227/80 A
AU 59227/80A
AU 5922780 A
AU5922780 A
AU 5922780A
AU 534945 B2
AU534945 B2
AU 534945B2
Authority
AU
Australia
Prior art keywords
hypertensive agents
hypertensive
agents
Prior art date
1980-03-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU59227/80A
Other versions
AU5922780A
(en
Inventor
Alfred Chung
James Walter Ryan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Miami
Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1980-03-03
Filing date
1980-06-11
Publication date
1984-02-23
1980-06-11
Application filed by University of Miami
filed
Critical
University of Miami
1981-09-10
Publication of AU5922780A
publication
Critical
patent/AU5922780A/en
1984-02-23
Application granted
granted
Critical
1984-02-23
Publication of AU534945B2
publication
Critical
patent/AU534945B2/en
2000-06-11
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
C07D207/50—Nitrogen atoms
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/12—Antihypertensives
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D207/24—Oxygen or sulfur atoms
C07D207/26—2-Pyrrolidones
C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
C07K5/06—Dipeptides
C07K5/06086—Dipeptides with the first amino acid being basic
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
C07K5/06—Dipeptides
C07K5/06139—Dipeptides with the first amino acid being heterocyclic
C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K38/00—Medicinal preparations containing peptides
AU59227/80A
1980-03-03
1980-06-11
Anti-hypertensive agents
Ceased
AU534945B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
US121188
1980-03-03
US06/121,188
US4692459A
(en)
1979-08-14
1980-03-03
Anti-hypertensive agents
Publications (2)
Publication Number
Publication Date
AU5922780A
AU5922780A
(en)
1981-09-10
AU534945B2
true
AU534945B2
(en)
1984-02-23
Family
ID=22395126
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU59227/80A
Ceased
AU534945B2
(en)
1980-03-03
1980-06-11
Anti-hypertensive agents
Country Status (15)
Country
Link
US
(1)
US4692459A
(en)
EP
(1)
EP0035383B1
(en)
JP
(1)
JPS56164115A
(en)
AT
(1)
AT385038B
(en)
AU
(1)
AU534945B2
(en)
DD
(1)
DD158238A5
(en)
DE
(1)
DE3163812D1
(en)
DK
(1)
DK93081A
(en)
FI
(1)
FI76558C
(en)
IE
(1)
IE51259B1
(en)
IL
(1)
IL62203A
(en)
NZ
(1)
NZ194002A
(en)
PL
(1)
PL229971A1
(en)
PT
(1)
PT70158A1
(en)
ZA
(1)
ZA803486B
(en)
Families Citing this family (22)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4692458A
(en)
*
1980-03-05
1987-09-08
University Of Miami
Anti-hypertensive agents
JPS57209270A
(en)
*
1981-06-19
1982-12-22
Chugai Pharmaceut Co Ltd
Proline derivative
DK110285A
(en)
*
1984-03-12
1985-09-13
Pfizer
POLYPEPTIDES AND POLYPEPTIDE DERIVATIVES CONTAINING STATIN OR DERIVATIVES THEREOF AND PHARMACEUTICAL PREPARATIONS
US5025001A
(en)
*
1988-06-15
1991-06-18
Brigham And Women’s Hospital
S-nitroso derivatives of ACE inhibitors and the use thereof
US5356890A
(en)
*
1988-06-15
1994-10-18
Brigham And Women’s Hospital
S-nitroso derivatives of ace inhibitors and the use thereof
US5187183A
(en)
*
1988-06-15
1993-02-16
Brigham & Women’s Hospital
S-nitroso derivatives of ACE inhibitors and the use thereof
DE4010797A1
(en)
*
1990-04-04
1991-10-10
Hoechst Ag
SUBSTITUTED AZOLES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF
DE10115938A1
(en)
*
2001-03-30
2002-10-10
Medigene Ag Ges Fuer Molekular
Process for the preparation of oxirane carboxylic acids and derivatives thereof
US11229746B2
(en)
2006-06-22
2022-01-25
Excelsior Medical Corporation
Antiseptic cap
US9259535B2
(en)
2006-06-22
2016-02-16
Excelsior Medical Corporation
Antiseptic cap equipped syringe
US9078992B2
(en)
2008-10-27
2015-07-14
Pursuit Vascular, Inc.
Medical device for applying antimicrobial to proximal end of catheter
WO2013009998A2
(en)
2011-07-12
2013-01-17
Pursuit Vascular, Inc.
Device for delivery of antimicrobial agent into trans-dermal catheter
JP6822978B2
(en)
2015-05-08
2021-01-27
アイシーユー・メディカル・インコーポレーテッド
Medical connector configured to accept the emitter of a therapeutic agent
FI3525865T3
(en)
2016-10-14
2023-01-13
Sanitizing caps for medical connectors
WO2018204206A2
(en)
2017-05-01
2018-11-08
Icu Medical, Inc.
Medical fluid connectors and methods for providing additives in medical fluid lines
JP6600386B1
(en)
*
2018-07-06
2019-10-30
Kyb株式会社
Valve device
US11400195B2
(en)
2018-11-07
2022-08-02
Icu Medical, Inc.
Peritoneal dialysis transfer set with antimicrobial properties
US11517732B2
(en)
2018-11-07
2022-12-06
Icu Medical, Inc.
Syringe with antimicrobial properties
US11541220B2
(en)
2018-11-07
2023-01-03
Icu Medical, Inc.
Needleless connector with antimicrobial properties
US11541221B2
(en)
2018-11-07
2023-01-03
Icu Medical, Inc.
Tubing set with antimicrobial properties
US11534595B2
(en)
2018-11-07
2022-12-27
Icu Medical, Inc.
Device for delivering an antimicrobial composition into an infusion device
EP3883638A1
(en)
2018-11-21
2021-09-29
ICU Medical, Inc.
Antimicrobial device comprising a cap with ring and insert
Family Cites Families (8)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3947575A
(en)
*
1969-06-30
1976-03-30
E. R. Squibb & Sons, Inc.
Peptides as argiotensin converting enzyme inhibitors
US3832337A
(en)
*
1970-07-28
1974-08-27
Squibb & Sons Inc
Peptide enzyme inhibitors
US3891616A
(en)
*
1974-04-17
1975-06-24
Squibb & Sons Inc
Hypotensive {62 -homoaminoacid nonapeptides
US4046889A
(en)
*
1976-02-13
1977-09-06
E. R. Squibb & Sons, Inc.
Azetidine-2-carboxylic acid derivatives
US4052511A
(en)
*
1976-02-13
1977-10-04
E. R. Squibb & Sons, Inc.
Carboxyacylproline derivatives
US4053651A
(en)
*
1976-05-10
1977-10-11
E. R. Squibb & Sons, Inc.
Compounds and method for alleviating angiotensin related hypertension
US4113715A
(en)
*
1977-01-17
1978-09-12
E. R. Squibb & Sons, Inc.
Amino acid derivatives
GR73585B
(en)
*
1978-09-11
1984-03-26
Univ Miami
1979
1979-09-10
PT
PT70158A
patent/PT70158A1/en
unknown
1980
1980-03-03
US
US06/121,188
patent/US4692459A/en
not_active
Expired – Lifetime
1980-06-11
NZ
NZ194002A
patent/NZ194002A/en
unknown
1980-06-11
AU
AU59227/80A
patent/AU534945B2/en
not_active
Ceased
1980-06-11
ZA
ZA00803486A
patent/ZA803486B/en
unknown
1981
1981-02-24
IL
IL62203A
patent/IL62203A/en
unknown
1981-02-27
DE
DE8181300825T
patent/DE3163812D1/en
not_active
Expired
1981-02-27
EP
EP81300825A
patent/EP0035383B1/en
not_active
Expired
1981-03-02
AT
AT0097081A
patent/AT385038B/en
not_active
IP Right Cessation
1981-03-02
DK
DK93081A
patent/DK93081A/en
not_active
Application Discontinuation
1981-03-03
IE
IE460/81A
patent/IE51259B1/en
unknown
1981-03-03
JP
JP3042981A
patent/JPS56164115A/en
active
Granted
1981-03-03
DD
DD81228014A
patent/DD158238A5/en
not_active
IP Right Cessation
1981-03-03
FI
FI810663A
patent/FI76558C/en
not_active
IP Right Cessation
1981-03-03
PL
PL22997181A
patent/PL229971A1/xx
unknown
Also Published As
Publication number
Publication date
ATA97081A
(en)
1987-07-15
FI810663L
(en)
1981-09-04
FI76558B
(en)
1988-07-29
EP0035383B1
(en)
1984-05-30
AT385038B
(en)
1988-02-10
EP0035383A1
(en)
1981-09-09
DK93081A
(en)
1981-09-04
IE51259B1
(en)
1986-11-26
ZA803486B
(en)
1981-06-24
IE810460L
(en)
1981-09-03
JPS56164115A
(en)
1981-12-17
NZ194002A
(en)
1982-12-21
AU5922780A
(en)
1981-09-10
PT70158A1
(en)
1982-03-01
DE3163812D1
(en)
1984-07-05
PL229971A1
(en)
1982-02-01
DD158238A5
(en)
1983-01-05
IL62203A
(en)
1984-07-31
JPH03386B2
(en)
1991-01-07
US4692459A
(en)
1987-09-15
FI76558C
(en)
1988-11-10
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