AU5475886A – 3′-azido-3′-deoxythymidine
– Google Patents
AU5475886A – 3′-azido-3′-deoxythymidine
– Google Patents
3′-azido-3′-deoxythymidine
Info
Publication number
AU5475886A
AU5475886A
AU54758/86A
AU5475886A
AU5475886A
AU 5475886 A
AU5475886 A
AU 5475886A
AU 54758/86 A
AU54758/86 A
AU 54758/86A
AU 5475886 A
AU5475886 A
AU 5475886A
AU 5475886 A
AU5475886 A
AU 5475886A
Authority
AU
Australia
Prior art keywords
deoxythymidine
azido
Prior art date
1985-03-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU54758/86A
Other versions
AU572019B2
(en
Inventor
David Walter Barry
George Andrew Freeman
Phillip Allen Furman
Sandra Nusinoff Lehrman
Janet Lister Rideout
Martha Heider St. Clair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-03-16
Filing date
1986-03-14
Publication date
1986-09-18
Family has litigation
First worldwide family litigation filed
litigation
Critical
https://patents.darts-ip.com/?family=27516579&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU5475886(A)
«Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
1985-03-16
Priority claimed from GB858506869A
external-priority
patent/GB8506869D0/en
1985-05-09
Priority claimed from GB858511774A
external-priority
patent/GB8511774D0/en
1985-09-17
Priority claimed from US06/776,899
external-priority
patent/US4724232A/en
1985-09-27
Priority claimed from GB858523881A
external-priority
patent/GB8523881D0/en
1986-02-12
Priority claimed from GB868603450A
external-priority
patent/GB8603450D0/en
1986-03-14
Application filed by Wellcome Foundation Ltd
filed
Critical
Wellcome Foundation Ltd
1986-09-18
Publication of AU5475886A
publication
Critical
patent/AU5475886A/en
1988-04-28
Application granted
granted
Critical
1988-04-28
Publication of AU572019B2
publication
Critical
patent/AU572019B2/en
2006-03-14
Anticipated expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/70—Carbohydrates; Sugars; Derivatives thereof
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/70—Carbohydrates; Sugars; Derivatives thereof
A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K38/00—Medicinal preparations containing peptides
A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
A61K38/19—Cytokines; Lymphokines; Interferons
A61K38/21—Interferons [IFN]
A61K38/212—IFN-alpha
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/12—Antivirals
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/12—Antivirals
A61P31/14—Antivirals for RNA viruses
A61P31/18—Antivirals for RNA viruses for HIV
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
C07H19/06—Pyrimidine radicals
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
C07H19/06—Pyrimidine radicals
C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
AU54758/86A
1985-03-16
1986-03-14
3′-azido-3′-deoxythymidine
Expired
AU572019B2
(en)
Applications Claiming Priority (10)
Application Number
Priority Date
Filing Date
Title
GB858506869A
GB8506869D0
(en)
1985-03-16
1985-03-16
Antiviral compound
GB8506869
1985-03-16
GB858511774A
GB8511774D0
(en)
1985-05-09
1985-05-09
Antiviral compounds
GB8511774
1985-05-09
US06/776,899
US4724232A
(en)
1985-03-16
1985-09-17
Treatment of human viral infections
US776899
1985-09-17
GB858523881A
GB8523881D0
(en)
1985-09-27
1985-09-27
Antiviral compounds
GB8523881
1985-09-27
GB8603450
1986-02-12
GB868603450A
GB8603450D0
(en)
1986-02-12
1986-02-12
Antiviral compounds
Related Child Applications (2)
Application Number
Title
Priority Date
Filing Date
AU12159/88A
Division
AU587739B2
(en)
1985-03-16
1988-02-24
Derivatives of 3′-azido-3′-deoxythymidine
AU12158/88A
Division
AU574620B1
(en)
1985-03-16
1988-02-24
Use of 3′-azido-3′-deoxythymidine
Publications (2)
Publication Number
Publication Date
AU5475886A
true
AU5475886A
(en)
1986-09-18
AU572019B2
AU572019B2
(en)
1988-04-28
Family
ID=27516579
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU54758/86A
Expired
AU572019B2
(en)
1985-03-16
1986-03-14
3′-azido-3′-deoxythymidine
Country Status (21)
Country
Link
EP
(2)
EP0291633B1
(en)
JP
(1)
JPH0780898B2
(en)
AP
(1)
AP11A
(en)
AT
(4)
ATE113603T1
(en)
AU
(1)
AU572019B2
(en)
CA
(1)
CA1238277A
(en)
CS
(1)
CS385191A3
(en)
CY
(2)
CY1508A
(en)
DE
(4)
DE3608606A1
(en)
DK
(1)
DK164392C
(en)
FI
(1)
FI85978C
(en)
GR
(1)
GR860712B
(en)
HK
(2)
HK85789A
(en)
IE
(1)
IE56503B1
(en)
IL
(1)
IL78158A
(en)
MC
(1)
MC1742A1
(en)
MY
(1)
MY102693A
(en)
NZ
(1)
NZ215486A
(en)
PH
(1)
PH24388A
(en)
PT
(1)
PT82199B
(en)
SG
(1)
SG62889G
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
USRE33887E
(en)
*
1987-06-22
1992-04-14
Hoffmann-La Roche Inc.
Anti-retroviral compounds
Families Citing this family (46)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DK167377B1
(en)
*
1985-09-17
1993-10-25
Wellcome Found
3′-AZIDOPYRIMIDINE NUCLEOSIDES OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF USED FOR TREATMENT OR PROPHYLAXY FOR A HUMAN RETROVIRUS INFECTION
US4841039A
(en)
*
1986-05-01
1989-06-20
Emory University
2′,3′-dideoxy-5-substituted uridines and related compounds as antiviral agents
US5084445A
(en)
*
1986-05-01
1992-01-28
University Of Georgia Research Foundation, Inc.
3′-azido-2′,3′-dideoxy-5-methylcytidine
US5077279A
(en)
*
1986-05-01
1991-12-31
University Of Georgia Research Foundation, Inc.
3′-azido-2′,3′-dideoxy-5-methylcytidine anti-viral composition
US4916122A
(en)
*
1987-01-28
1990-04-10
University Of Georgia Research Foundation, Inc.
3′-Azido-2′,3′-dideoxyuridine anti-retroviral composition
WO1988003804A2
(en)
*
1986-11-21
1988-06-02
Max-Planck-Gesellschaft Zur Förderung Der Wissensc
Method of treating viral infections in humans and compositions therefor
US4880782A
(en)
*
1986-11-21
1989-11-14
Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V.
Method of treating viral infections in humans and compositions therefor
SE8605503D0
(en)
*
1986-12-19
1986-12-19
Astra Laekemedel Ab
NOVEL MEDICINAL USE
US5190926A
(en)
*
1987-01-28
1993-03-02
University Of Georgia Research Foundation, Inc.
3′-azido-2′,3′-dideoxypyrimidines and related compounds as antiviral agents
PH24812A
(en)
*
1987-03-16
1990-10-30
Wellcome Found
Therapeutic nucleosides
EP0286825A3
(en)
*
1987-03-18
1989-04-12
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
Use of 3′-fluro-3′ deoxythymidine for the manufacture of a medicament for the treatment of virus infections
EP0282618A1
(en)
*
1987-03-18
1988-09-21
Vereniging Het Nederlands Kanker Instituut
1-Deoxynojirimycin as an anti-HIV therapeutic
US4950652A
(en)
*
1987-03-23
1990-08-21
Hem Research, Inc.
dsRNAs for combination therapy in the treatment of viral diseases
DK161788A
(en)
*
1987-03-25
1988-09-26
Wellcome Found
PROCEDURE FOR PREPARING ZIDOVUDIN
GB8707421D0
(en)
*
1987-03-27
1987-04-29
Wellcome Found
Pharmaceutical formulations
US5185437A
(en)
*
1987-04-09
1993-02-09
Burroughs Wellcome Co.
Therapeutic nucleosides
IL86007A0
(en)
*
1987-04-09
1988-09-30
Wellcome Found
6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
IL86009A
(en)
*
1987-04-10
1991-09-16
Us Health
Liposome-encapsulated phosphorylated nucleosides for treatment of retroviral diseases
SE8701605D0
(en)
*
1987-04-16
1987-04-16
Astra Ab
NOVEL MEDICINAL COMPOUNDS
US5215970A
(en)
*
1987-04-16
1993-06-01
Medivir Ab
Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
ATE72122T1
(en)
*
1987-04-24
1992-02-15
Wellcome Found
ANTIVIRAL BLENDS.
US4863927A
(en)
*
1987-05-11
1989-09-05
Merck & Co., Inc.
1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
YU110888A
(en)
*
1987-06-10
1989-08-31
Wellcome Found
Process for obtaining timine derivatives
SU1548182A1
(en)
*
1987-12-29
1990-03-07
Институт молекулярной биологии АН СССР
5ъ-phosphonates of 3ъ-azido-2ъ,3ъ-didesoxynucleosides as specific inhibitors of aids virus in human lymphocyte culture
US5384396A
(en)
*
1988-02-23
1995-01-24
The University Of Georgia Research Foundation, Inc.
Process for the deoxygenation of nucleosides
DE3824669C2
(en)
*
1988-07-20
1999-05-06
Wondrak Ewald M
Use of trisodium phosphonoformate
US4987224A
(en)
*
1988-08-02
1991-01-22
University Of Georgia Research Foundation, Inc.
Method of preparation of 2′,3′-dideoxynucleosides
EP0355245A1
(en)
*
1988-08-26
1990-02-28
Michel Vandevelde
Use of retrovirus reverse transcriptase inhibiting agents
HU205089B
(en)
*
1989-05-31
1992-03-30
Biogal Gyogyszergyar
Process for producing new thymine derivatives and pharmaceutical compositions comprising same
ES2029769A6
(en)
*
1989-11-09
1992-09-01
Asta Pharma Ag
Pharmaceutical compositions comprising sulfur containing carboxylic acids as the active agent as well as their use for combatting retroviruses.
DE69102764T2
(en)
*
1990-04-19
1995-02-09
Previsan Sa
AZOIC DERIVATIVES, PHARMACEUTICAL AND DISINFECTING COMPOSITIONS CONTAINING THESE SUBSTANCES AND THEIR USE AGAINST AIDS.
US5585367A
(en)
*
1990-04-19
1996-12-17
Previsan S.A.
Method of treating humans and animals infected with viruses of the retrovirus group
GB9104740D0
(en)
*
1991-03-06
1991-04-17
Wellcome Found
Antiviral nucleoside combination
US6812233B1
(en)
1991-03-06
2004-11-02
Emory University
Therapeutic nucleosides
IL102548A
(en)
*
1991-08-02
1998-08-16
Medivir Ab
Thiourea derivatives for use in the preparation of medicaments for the inhibition of hiv and the treatment of aids and some such novel compounds
US5593993A
(en)
*
1991-08-02
1997-01-14
Medivir Ab
Method for inhibition of HIV related viruses
US6177435B1
(en)
1992-05-13
2001-01-23
Glaxo Wellcome Inc.
Therapeutic combinations
DK0639971T3
(en)
*
1992-05-13
2000-03-20
Wellcome Found
Therapeutic combinations
GR920100326A
(en)
*
1992-07-21
1994-03-31
Medivir Ag
Compounds and methods for inhibition of hiv related viruses.
DE4336640A1
(en)
*
1993-10-22
1995-04-27
Deutsches Rheuma Forschungszen
Metal chelates, process for the preparation thereof and the use thereof as antiviral pharmaceuticals
CA2270600A1
(en)
1999-05-03
2000-11-03
Infectio Recherche Inc.
Method and formulations for the treatment of diseases, particularly those caused by human immunodeficiency virus and leishmania
DE122008000016I1
(en)
2001-10-26
2011-12-01
Angeletti P Ist Richerche Bio
N-substituted hydroxypyrimidinone carboxamide-inhibiting HIV integrase.
EP2316469A1
(en)
2002-02-22
2011-05-04
Shire LLC
Delivery system and methods for protecting and administering dextroamphetamine
EP1579862A1
(en)
2004-03-25
2005-09-28
Boehringer Ingelheim Vetmedica Gmbh
Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2
(en)
2004-03-25
2015-03-17
Boehringer Ingelheim Vetmedica Gmbh
Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
WO2022008025A1
(en)
*
2020-07-05
2022-01-13
Since & Technology Development Fund Authority
2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto
Family Cites Families (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
IE73219B1
(en)
*
1985-03-16
1997-05-07
Wellcome Found
Therapeutic nucleosides
1986
1986-03-14
EP
EP88101790A
patent/EP0291633B1/en
not_active
Expired – Lifetime
1986-03-14
CA
CA000504126A
patent/CA1238277A/en
not_active
Expired
1986-03-14
DE
DE19863608606
patent/DE3608606A1/en
not_active
Withdrawn
1986-03-14
AU
AU54758/86A
patent/AU572019B2/en
not_active
Expired
1986-03-14
AT
AT88101795T
patent/ATE113603T1/en
not_active
IP Right Cessation
1986-03-14
IE
IE677/86A
patent/IE56503B1/en
not_active
IP Right Cessation
1986-03-14
NZ
NZ215486A
patent/NZ215486A/en
unknown
1986-03-14
EP
EP86301897A
patent/EP0196185B1/en
not_active
Expired
1986-03-14
IL
IL78158A
patent/IL78158A/en
unknown
1986-03-14
AP
APAP/P/1986/000027A
patent/AP11A/en
active
1986-03-14
AT
AT0068386A
patent/AT390000B/en
not_active
IP Right Cessation
1986-03-14
CY
CY1508A
patent/CY1508A/en
unknown
1986-03-14
FI
FI861069A
patent/FI85978C/en
not_active
IP Right Cessation
1986-03-14
GR
GR860712A
patent/GR860712B/en
unknown
1986-03-14
DE
DE198686301897T
patent/DE196185T1/en
active
Pending
1986-03-14
AT
AT88101790T
patent/ATE81978T1/en
not_active
IP Right Cessation
1986-03-14
PH
PH33532A
patent/PH24388A/en
unknown
1986-03-14
DE
DE8888101790T
patent/DE3687069T2/en
not_active
Expired – Lifetime
1986-03-14
PT
PT82199A
patent/PT82199B/en
unknown
1986-03-14
AT
AT86301897T
patent/ATE44464T1/en
not_active
IP Right Cessation
1986-03-14
DK
DK118086A
patent/DK164392C/en
not_active
IP Right Cessation
1986-03-14
MC
MC861828A
patent/MC1742A1/en
unknown
1986-03-14
DE
DE3650130T
patent/DE3650130T3/en
not_active
Expired – Lifetime
1987
1987-09-25
MY
MYPI87001943A
patent/MY102693A/en
unknown
1988
1988-03-29
JP
JP63073488A
patent/JPH0780898B2/en
not_active
Expired – Lifetime
1989
1989-09-11
SG
SG628/89A
patent/SG62889G/en
unknown
1989-10-26
HK
HK857/89A
patent/HK85789A/en
not_active
IP Right Cessation
1991
1991-12-17
CS
CS913851A
patent/CS385191A3/en
unknown
1995
1995-10-19
HK
HK164395A
patent/HK164395A/en
not_active
IP Right Cessation
1996
1996-11-22
CY
CY188996A
patent/CY1889A/en
unknown
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
USRE33887E
(en)
*
1987-06-22
1992-04-14
Hoffmann-La Roche Inc.
Anti-retroviral compounds
Also Published As
Publication number
Publication date
IL78158A
(en)
1988-04-29
GR860712B
(en)
1986-07-16
FI85978C
(en)
1992-06-25
ATE81978T1
(en)
1992-11-15
DE3687069T2
(en)
1993-03-25
JPS63290895A
(en)
1988-11-28
HK85789A
(en)
1989-11-03
DK118086A
(en)
1986-09-17
AT390000B
(en)
1990-02-26
AP8600027A0
(en)
1986-02-01
ATE44464T1
(en)
1989-07-15
AP11A
(en)
1987-12-22
DK164392C
(en)
1992-11-09
CS385191A3
(en)
1992-05-13
DE196185T1
(en)
1987-04-30
IE56503B1
(en)
1991-08-14
EP0291633B1
(en)
1992-11-04
DE3650130T3
(en)
2003-07-24
DE3650130D1
(en)
1994-12-08
DE3687069D1
(en)
1992-12-10
CA1238277A
(en)
1988-06-21
NZ215486A
(en)
1988-09-29
JPH0780898B2
(en)
1995-08-30
FI861069A0
(en)
1986-03-14
FI85978B
(en)
1992-03-13
IL78158A0
(en)
1986-07-31
CY1508A
(en)
1990-08-03
MC1742A1
(en)
1987-02-26
EP0196185A3
(en)
1988-01-13
HK164395A
(en)
1995-10-27
MY102693A
(en)
1992-09-30
FI861069A
(en)
1986-09-17
CY1889A
(en)
1996-11-22
DK118086D0
(en)
1986-03-14
ATE113603T1
(en)
1994-11-15
EP0291633A1
(en)
1988-11-23
PT82199B
(en)
1990-11-07
DK164392B
(en)
1992-06-22
EP0196185B1
(en)
1989-07-12
PT82199A
(en)
1986-04-01
ATA68386A
(en)
1989-08-15
DE3650130T2
(en)
1995-03-16
AU572019B2
(en)
1988-04-28
IE860677L
(en)
1986-09-16
EP0196185A2
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1986-10-01
DE3608606A1
(en)
1986-09-18
PH24388A
(en)
1990-06-13
SG62889G
(en)
1990-01-26
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