AU5476580A – Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
– Google Patents
AU5476580A – Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
– Google Patents
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
Info
Publication number
AU5476580A
AU5476580A
AU54765/80A
AU5476580A
AU5476580A
AU 5476580 A
AU5476580 A
AU 5476580A
AU 54765/80 A
AU54765/80 A
AU 54765/80A
AU 5476580 A
AU5476580 A
AU 5476580A
AU 5476580 A
AU5476580 A
AU 5476580A
Authority
AU
Australia
Prior art keywords
pyrido
hexahydro
indole
aryl
derivative
Prior art date
1979-01-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU54765/80A
Other versions
AU521986B2
(en
Inventor
William Mckowan Welch Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1979-01-23
Filing date
1980-01-21
Publication date
1980-07-31
1980-01-21
Application filed by Pfizer Inc
filed
Critical
Pfizer Inc
1980-07-31
Publication of AU5476580A
publication
Critical
patent/AU5476580A/en
1982-05-13
Application granted
granted
Critical
1982-05-13
Publication of AU521986B2
publication
Critical
patent/AU521986B2/en
2000-01-21
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D307/32—Oxygen atoms
C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/20—Hypnotics; Sedatives
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/22—Anxiolytics
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
C07C51/42—Separation; Purification; Stabilisation; Use of additives
C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D307/20—Oxygen atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 – C07D463/00
C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 – C07D463/00 in which the condensed system contains two hetero rings
C07D471/04—Ortho-condensed systems
AU54765/80A
1979-01-23
1980-01-21
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
Ceased
AU521986B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
US005698
1979-01-23
US06/005,698
US4224329A
(en)
1979-01-23
1979-01-23
2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
Related Child Applications (1)
Application Number
Title
Priority Date
Filing Date
AU76883/81A
Addition
AU532598B2
(en)
1981-10-27
1981-10-27
5-aryl-2-hydroxytetrahydrofurans
Publications (2)
Publication Number
Publication Date
AU5476580A
true
AU5476580A
(en)
1980-07-31
AU521986B2
AU521986B2
(en)
1982-05-13
Family
ID=21717248
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU54765/80A
Ceased
AU521986B2
(en)
1979-01-23
1980-01-21
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
Country Status (34)
Country
Link
US
(1)
US4224329A
(en)
JP
(4)
JPS55100386A
(en)
KR
(1)
KR830001932A
(en)
AR
(1)
AR231291A1
(en)
AT
(1)
AT376674B
(en)
AU
(1)
AU521986B2
(en)
BE
(1)
BE881283A
(en)
CA
(1)
CA1144168A
(en)
CH
(2)
CH648314A5
(en)
CS
(4)
CS221809B2
(en)
DD
(2)
DD149071A5
(en)
DE
(1)
DE3002367A1
(en)
DK
(1)
DK25580A
(en)
EG
(1)
EG14767A
(en)
FI
(1)
FI800179A
(en)
FR
(3)
FR2447379A1
(en)
GB
(1)
GB2041925B
(en)
GR
(1)
GR73567B
(en)
HU
(3)
HU188201B
(en)
IE
(1)
IE49500B1
(en)
IL
(1)
IL59189A
(en)
IN
(1)
IN153300B
(en)
IT
(1)
IT1149927B
(en)
LU
(1)
LU82105A1
(en)
NL
(1)
NL8000385A
(en)
NO
(2)
NO151895C
(en)
NZ
(3)
NZ192175A
(en)
PH
(4)
PH15736A
(en)
PL
(4)
PL126032B1
(en)
PT
(1)
PT70724A
(en)
SE
(3)
SE441358B
(en)
SU
(3)
SU1168094A3
(en)
YU
(2)
YU269379A
(en)
ZA
(1)
ZA796374B
(en)
Families Citing this family (17)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4432978A
(en)
*
1979-07-30
1984-02-21
Pfizer Inc.
Hexahydro-trans-pyridoindole
US4337250A
(en)
*
1979-07-30
1982-06-29
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4431646A
(en)
*
1979-07-30
1984-02-14
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4431649A
(en)
*
1979-07-30
1984-02-14
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4427679A
(en)
1981-01-16
1984-01-24
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4467090A
(en)
*
1982-09-30
1984-08-21
Pfizer Inc.
Compound, 8-fluoro-5-(p-fluorophenyl)-2-[4-(p-fluorophenyl)-4-hydroxybutyryl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
US4477669A
(en)
*
1982-09-30
1984-10-16
Pfizer Inc.
Processes and intermediates useful in the preparation of flutroline
US4451655A
(en)
*
1982-05-17
1984-05-29
Pfizer Inc.
Process for preparing carboline derivatives and compounds used in their preparation
US4568748A
(en)
*
1982-09-30
1986-02-04
Pfizer Inc.
2-Carbobenzoxy-8-fluoro-5-(p-fluorophenyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
US4698444A
(en)
*
1982-09-30
1987-10-06
Pfizer Inc.
1,1-bis(p-fluorophenyl)urea
JPS61248502A
(en)
*
1985-04-26
1986-11-05
Pioneer Electronic Corp
Bonding method for magnetic material
US4636563A
(en)
*
1985-09-16
1987-01-13
American Home Products Corporation
Antipsychotic γ-carbolines
US4672117A
(en)
*
1985-09-16
1987-06-09
American Home Products Corporation
Antipsychotic gamma-carbolines
US4798896A
(en)
*
1988-01-19
1989-01-17
American Home Products Corporation
Antipsychotic gamma-carboline N-oxides
US5075315A
(en)
*
1990-05-17
1991-12-24
Mcneilab, Inc.
Antipsychotic hexahydro-2H-indeno[1,2-c]pyridine derivatives
IL143830A0
(en)
*
1998-12-21
2002-04-21
Janssen Pharmaceutica Nv
BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS
RU2329044C1
(en)
*
2006-11-16
2008-07-20
Андрей Александрович Иващенко
Ligands of 5-ht6 receptors, pharmaceutical formulation, production method and medical product
Family Cites Families (9)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
CA551241A
(en)
*
1958-01-07
S. Abbott Leslie
Production of substituted piperidines
US3382250A
(en)
*
1966-12-07
1968-05-07
Abbott Lab
Aroylalkyl derivatives of 1, 2, 3, 4-tetrahydro-5h-pyrido[4, 3b]indoles
US3687961A
(en)
*
1971-05-03
1972-08-29
Abbott Lab
8-fluoro-2-{8 3-(4-fluorophenylanilinopropyl{9 -gamma-carboline
AR205452A1
(en)
*
1973-12-06
1976-05-07
Endo Lab
METHOD TO PREPARE NEW TRANS-2, 3, 4, 4A, 5, 9B-HEXAHYDRO-5-PHENYL-1H-PYRID (4,3-B) INDOLES
JPS50126699A
(en)
*
1974-03-20
1975-10-04
AR207799A1
(en)
*
1974-04-01
1976-10-29
Pfizer
PROCEDURE TO PREPARE AZACICLO (3,4-A) -N-PHENYLINDOLES-2-SUBSTITUTE
US4001263A
(en)
*
1974-04-01
1977-01-04
Pfizer Inc.
5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
SE7702301L
(en)
*
1976-04-08
1977-10-09
Endo Lab
TRANS-HEXAHYDRO-PYRIDO-INDOLES
SE441448B
(en)
*
1977-05-23
1985-10-07
Pfizer
SET TO MAKE HEXAHYDRO-GAMMA CARBOL COMPOUNDS
1979
1979-01-23
US
US06/005,698
patent/US4224329A/en
not_active
Expired – Lifetime
1979-10-17
IN
IN726/DEL/79A
patent/IN153300B/en
unknown
1979-10-22
PH
PH23203A
patent/PH15736A/en
unknown
1979-11-05
YU
YU02693/79A
patent/YU269379A/en
unknown
1979-11-19
EG
EG668/79D
patent/EG14767A/en
active
1979-11-20
NZ
NZ192175A
patent/NZ192175A/en
unknown
1979-11-20
NZ
NZ197582A
patent/NZ197582A/en
unknown
1979-11-20
NZ
NZ197581A
patent/NZ197581A/en
unknown
1979-11-20
AR
AR278965A
patent/AR231291A1/en
active
1979-11-23
ZA
ZA00796374A
patent/ZA796374B/en
unknown
1979-12-28
NO
NO794317A
patent/NO151895C/en
unknown
1980
1980-01-03
CS
CS815712A
patent/CS221809B2/en
unknown
1980-01-03
CS
CS8098A
patent/CS221806B2/en
unknown
1980-01-03
CS
CS815710A
patent/CS221807B2/en
unknown
1980-01-03
CS
CS815711A
patent/CS221808B2/en
unknown
1980-01-04
HU
HU822859A
patent/HU188201B/en
unknown
1980-01-04
HU
HU8023A
patent/HU184712B/en
unknown
1980-01-04
HU
HU822858A
patent/HU189174B/en
unknown
1980-01-04
SU
SU802865803A
patent/SU1168094A3/en
active
1980-01-07
PL
PL1980231005A
patent/PL126032B1/en
unknown
1980-01-07
PL
PL1980221248A
patent/PL120774B1/en
unknown
1980-01-07
PL
PL1980231006A
patent/PL126532B1/en
unknown
1980-01-07
PL
PL1980231004A
patent/PL126867B1/en
unknown
1980-01-15
SE
SE8000329A
patent/SE441358B/en
unknown
1980-01-15
GB
GB8001232A
patent/GB2041925B/en
not_active
Expired
1980-01-18
CA
CA000343988A
patent/CA1144168A/en
not_active
Expired
1980-01-21
CH
CH5785/83A
patent/CH648314A5/en
not_active
IP Right Cessation
1980-01-21
GR
GR60998A
patent/GR73567B/el
unknown
1980-01-21
CH
CH456/80A
patent/CH651040A5/en
not_active
IP Right Cessation
1980-01-21
JP
JP561180A
patent/JPS55100386A/en
active
Granted
1980-01-21
AU
AU54765/80A
patent/AU521986B2/en
not_active
Ceased
1980-01-22
IT
IT19373/80A
patent/IT1149927B/en
active
1980-01-22
IL
IL59189A
patent/IL59189A/en
unknown
1980-01-22
NL
NL8000385A
patent/NL8000385A/en
not_active
Application Discontinuation
1980-01-22
LU
LU82105A
patent/LU82105A1/en
unknown
1980-01-22
AT
AT0033380A
patent/AT376674B/en
not_active
IP Right Cessation
1980-01-22
BE
BE0/199065A
patent/BE881283A/en
not_active
IP Right Cessation
1980-01-22
KR
KR1019800000225A
patent/KR830001932A/en
unknown
1980-01-22
IE
IE121/80A
patent/IE49500B1/en
unknown
1980-01-22
FR
FR8001301A
patent/FR2447379A1/en
active
Granted
1980-01-22
DK
DK25580A
patent/DK25580A/en
not_active
Application Discontinuation
1980-01-22
FI
FI800179A
patent/FI800179A/en
not_active
Application Discontinuation
1980-01-22
DD
DD80218578A
patent/DD149071A5/en
unknown
1980-01-23
PT
PT70724A
patent/PT70724A/en
unknown
1980-01-23
DE
DE19803002367
patent/DE3002367A1/en
not_active
Ceased
1980-05-16
JP
JP6515580A
patent/JPS5636487A/en
active
Pending
1980-05-16
JP
JP55065153A
patent/JPS5855151B2/en
not_active
Expired
1980-05-16
JP
JP6515480A
patent/JPS5636475A/en
active
Pending
1980-05-28
FR
FR8011816A
patent/FR2453175A1/en
active
Granted
1980-05-28
FR
FR8011815A
patent/FR2453174A1/en
active
Granted
1980-06-17
PH
PH24155A
patent/PH15086A/en
unknown
1980-06-17
PH
PH24153A
patent/PH15072A/en
unknown
1980-06-17
PH
PH24154A
patent/PH17773A/en
unknown
1981
1981-01-22
DD
DD22761181A
patent/DD156369A5/en
unknown
1981-01-26
SU
SU813233005A
patent/SU1080746A3/en
active
1981-01-26
SU
SU813233012A
patent/SU1333239A3/en
active
1983
1983-12-13
YU
YU02421/83A
patent/YU242183A/en
unknown
1984
1984-07-27
NO
NO843041A
patent/NO843041L/en
unknown
1984-09-11
SE
SE8404554A
patent/SE8404554D0/en
unknown
1984-09-11
SE
SE8404555A
patent/SE8404555D0/en
not_active
Application Discontinuation
Also Published As
Publication number
Publication date
IN153300B
(en)
1984-06-30
SE8000329L
(en)
1980-07-24
BE881283A
(en)
1980-07-22
CH648314A5
(en)
1985-03-15
SE8404555L
(en)
1984-09-11
NL8000385A
(en)
1980-07-25
FR2447379A1
(en)
1980-08-22
NO151895B
(en)
1985-03-18
JPS5636486A
(en)
1981-04-09
FR2453174B1
(en)
1983-07-29
PL126532B1
(en)
1983-08-31
FI800179A
(en)
1980-07-24
FR2453174A1
(en)
1980-10-31
PL221248A1
(en)
1980-12-01
YU242183A
(en)
1984-06-30
DD156369A5
(en)
1982-08-18
PT70724A
(en)
1980-02-01
NO794317L
(en)
1980-07-24
LU82105A1
(en)
1980-08-08
SU1333239A3
(en)
1987-08-23
EG14767A
(en)
1985-12-31
PH15736A
(en)
1983-03-18
DK25580A
(en)
1980-07-24
HU184712B
(en)
1984-10-29
JPS55100386A
(en)
1980-07-31
IT1149927B
(en)
1986-12-10
ZA796374B
(en)
1980-11-26
IE49500B1
(en)
1985-10-16
JPS5740151B2
(en)
1982-08-25
NZ192175A
(en)
1984-05-31
GB2041925B
(en)
1982-10-20
YU269379A
(en)
1984-04-30
US4224329A
(en)
1980-09-23
DD149071A5
(en)
1981-06-24
ATA33380A
(en)
1984-05-15
CA1144168A
(en)
1983-04-05
SU1168094A3
(en)
1985-07-15
NO151895C
(en)
1985-06-26
SE8404554L
(en)
1984-09-11
DE3002367A1
(en)
1980-07-24
NO843041L
(en)
1980-07-24
CH651040A5
(en)
1985-08-30
AT376674B
(en)
1984-12-27
CS221809B2
(en)
1983-04-29
JPS5636487A
(en)
1981-04-09
JPS5636475A
(en)
1981-04-09
FR2447379B1
(en)
1983-08-19
IT8019373D0
(en)
1980-01-22
IE800121L
(en)
1980-07-23
AU521986B2
(en)
1982-05-13
CS221808B2
(en)
1983-04-29
SE8404554D0
(en)
1984-09-11
HU189174B
(en)
1986-06-30
PL126032B1
(en)
1983-07-30
IL59189A0
(en)
1980-05-30
SE8404555D0
(en)
1984-09-11
PH15072A
(en)
1982-06-03
SE441358B
(en)
1985-09-30
NZ197582A
(en)
1984-05-31
FR2453175B1
(en)
1983-07-29
IL59189A
(en)
1984-01-31
PL126867B1
(en)
1983-09-30
KR830001932A
(en)
1983-05-19
PL120774B1
(en)
1982-03-31
AR231291A1
(en)
1984-10-31
PH15086A
(en)
1982-07-02
FR2453175A1
(en)
1980-10-31
GB2041925A
(en)
1980-09-17
SU1080746A3
(en)
1984-03-15
HU188201B
(en)
1986-03-28
CS221806B2
(en)
1983-04-29
CS221807B2
(en)
1983-04-29
JPS5855151B2
(en)
1983-12-08
PH17773A
(en)
1984-12-11
GR73567B
(en)
1984-03-16
NZ197581A
(en)
1984-05-31
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(en)
1983-09-08
Indole derivatives
AU536316B2
(en)
1984-05-03
2,3-dihydro-1h-indole derivatives
AU534288B2
(en)
1984-01-19
Naphthyridine derivatives
AU6151380A
(en)
1981-03-05
Phthalimidine derivatives
AU533566B2
(en)
1983-12-01
Aminoalkylbenzene derivatives
AU531348B2
(en)
1983-08-18
1,8 naphthyridine derivatives
AU521986B2
(en)
1982-05-13
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
AU516325B2
(en)
1981-05-28
Spiro-imidazolidinedione derivatives
AU529742B2
(en)
1983-06-16
Alkyl-ketohexopyranoside derivatives
AU534806B2
(en)
1984-02-16
3-vinyl-cephalosporin derivatives
AU527185B2
(en)
1983-02-17
Indole derivatives
AU533797B2
(en)
1983-12-08
Thioethylamide derivatives
AU4847179A
(en)
1980-01-03
Indole derivatives
AU526214B2
(en)
1982-12-23
Pteridin derivatives
AU520245B2
(en)
1982-01-21
Glycerylphosphoryl derivatives
AU6080680A
(en)
1981-02-05
10-oco-benzo(5,6) cyclohepta-(1,2-6) pyrrole derivatives
AU8378182A
(en)
1982-11-25
Substituted tryptamine derivatives of thienyloxy- propanolamines
AU540977B2
(en)
1984-12-13
Preparation of vincamine derivatives
AU530761B2
(en)
1983-07-28
Halo-vincamone derivatives
AU522699B2
(en)
1982-06-24
Tetrahydrothiopyrano(2,3-b)indole derivatives
AU533484B2
(en)
1983-11-24
Tetrahydrochinoline derivatives
AU534271B2
(en)
1984-01-12
S-triazolo(3,4-c)benzo-as-triazine derivatives
AU534308B2
(en)
1984-01-19
15-hydroxyimino-e-homo-eburnane derivatives
AU518068B2
(en)
1981-09-10
15-sulfonamidoprostaglandin derivatives
AU538185B2
(en)
1984-08-02
Tetrahydrothiopyrano(3,2-b)indole derivatives
None