AU569072B2 – Ultrasound contrasting agent containing microparticles and gas micro bubbles
– Google Patents
AU569072B2 – Ultrasound contrasting agent containing microparticles and gas micro bubbles
– Google Patents
Ultrasound contrasting agent containing microparticles and gas micro bubbles
Info
Publication number
AU569072B2
AU569072B2
AU26806/84A
AU2680684A
AU569072B2
AU 569072 B2
AU569072 B2
AU 569072B2
AU 26806/84 A
AU26806/84 A
AU 26806/84A
AU 2680684 A
AU2680684 A
AU 2680684A
AU 569072 B2
AU569072 B2
AU 569072B2
Authority
AU
Australia
Prior art keywords
agent containing
containing microparticles
micro bubbles
contrasting agent
gas micro
Prior art date
1983-04-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU26806/84A
Other versions
AU2680684A
(en
Inventor
Jurgen Hilmann
Lothar Lange
Ingfried Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1983-04-15
Filing date
1984-04-13
Publication date
1988-01-21
1984-04-13
Application filed by Schering AG
filed
Critical
Schering AG
1984-10-18
Publication of AU2680684A
publication
Critical
patent/AU2680684A/en
1988-01-21
Application granted
granted
Critical
1988-01-21
Publication of AU569072B2
publication
Critical
patent/AU569072B2/en
2004-04-13
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/22—Echographic preparations; Ultrasound imaging preparation Optoacoustic imaging preparations
A61K49/222—Echographic preparations; Ultrasound imaging preparation Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
A61B2017/22089—Gas-bubbles
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 – A61B50/00, e.g. for luxation treatment or for protecting wound edges
A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
A61B2090/3925—Markers, e.g. radio-opaque or breast lesions markers ultrasonic
Abstract
1. Contrast medium containing microparticles and gas bubbles for ultrasound diagnostics, characterised in that it contains microparticles of a mixture of a semi-solid or liquid surface-active substance and a non-surface-active solid in a liquid carrier.
AU26806/84A
1983-04-15
1984-04-13
Ultrasound contrasting agent containing microparticles and gas micro bubbles
Ceased
AU569072B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE3313947A
DE3313947A1
(en)
1983-04-15
1983-04-15
MICROPARTICLES AND GAS BUBBLES CONTAINING ULTRASONIC CONTRASTING AGENTS
DE3313947
1983-04-15
Publications (2)
Publication Number
Publication Date
AU2680684A
AU2680684A
(en)
1984-10-18
AU569072B2
true
AU569072B2
(en)
1988-01-21
Family
ID=6196666
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU26806/84A
Ceased
AU569072B2
(en)
1983-04-15
1984-04-13
Ultrasound contrasting agent containing microparticles and gas micro bubbles
Country Status (12)
Country
Link
EP
(1)
EP0123235B1
(en)
JP
(1)
JPS59205329A
(en)
AT
(1)
ATE36959T1
(en)
AU
(1)
AU569072B2
(en)
CA
(1)
CA1232837A
(en)
DE
(2)
DE3313947A1
(en)
DK
(1)
DK165622C
(en)
FI
(1)
FI81265C
(en)
IE
(1)
IE57197B1
(en)
NO
(1)
NO163669C
(en)
NZ
(1)
NZ207854A
(en)
ZA
(1)
ZA842800B
(en)
Families Citing this family (84)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
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(en)
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1983-04-15
1992-08-25
Schering Aktiengesellschaft
Ultrasonic contrast medium comprising gas bubbles and solid lipophilic surfactant-containing microparticles and use thereof
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(en)
*
1988-10-07
1990-04-12
Schering Ag
ULTRASONIC CONTRASTING AGENTS FROM GAS BUBBLES AND MICROPARTICLES CONTAINING FATTY ACID
DE3529195A1
(en)
*
1985-08-14
1987-02-26
Max Planck Gesellschaft
CONTRAST AGENTS FOR ULTRASONIC EXAMINATIONS AND METHOD FOR THE PRODUCTION THEREOF
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*
1986-11-05
1987-11-26
Schering Ag
Ultrasonic manometry in a liquid using microbubbles
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*
1987-12-02
1989-08-17
Schering Ag
USE OF ULTRASONIC CONTRASTING AGENTS FOR ULTRASONIC LITHOTRIPSY
DE3741201A1
(en)
*
1987-12-02
1989-06-15
Schering Ag
ULTRASONIC PROCESS AND METHOD FOR IMPLEMENTING IT
US5425366A
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1988-02-05
1995-06-20
Schering Aktiengesellschaft
Ultrasonic contrast agents for color Doppler imaging
DE3803972A1
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*
1988-02-05
1989-08-10
Schering Ag
Ultrasound contrast media
DE3803971C2
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1988-02-05
1997-09-18
Schering Ag
Ultrasound contrast media
ATE109663T1
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1988-02-05
1994-08-15
Schering Ag
ULTRASONIC CONTRAST AGENT, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DIAGNOSTICS AND THERAPEUTICS.
FR2643252B1
(en)
*
1989-02-21
1991-06-07
Technomed Int Sa
APPARATUS FOR THE SELECTIVE DESTRUCTION OF CELLS INCLUDING SOFT TISSUES AND BONES WITHIN THE BODY OF A LIVING BODY BY IMPLOSION OF GAS BUBBLES
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(en)
1991-05-03
2006-08-01
Bracco International B.V.
Ultrasound contrast agents and methods of making and using them
US6613306B1
(en)
1990-04-02
2003-09-02
Bracco International B.V.
Ultrasound contrast agents and methods of making and using them
USRE39146E1
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1990-04-02
2006-06-27
Bracco International B.V.
Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
IN172208B
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1990-04-02
1993-05-01
Sint Sa
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1992-11-02
1995-08-29
Bracco International B.V.
Stable microbubble suspensions as enhancement agents for ultrasound echography
US5578292A
(en)
1991-11-20
1996-11-26
Bracco International B.V.
Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US6989141B2
(en)
1990-05-18
2006-01-24
Bracco International B.V.
Ultrasound contrast agents and methods of making and using them
US5205287A
(en)
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1990-04-26
1993-04-27
Hoechst Aktiengesellschaft
Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5190982A
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1990-04-26
1993-03-02
Hoechst Aktiengesellschaft
Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5137928A
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1990-04-26
1992-08-11
Hoechst Aktiengesellschaft
Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
AU636481B2
(en)
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1990-05-18
1993-04-29
Bracco International B.V.
Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
JP3247374B2
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1990-10-05
2002-01-15
ブラッコ インターナショナル ベスローテン フェンノートシャップ
A method for the production of stable suspensions of hollow gas-encapsulated microspheres suitable for ultrasound ecology
ATE151992T1
(en)
†
1991-06-03
1997-05-15
Nycomed Imaging As
IMPROVEMENTS REGARDING CONTRAST AGENTS
GB9200388D0
(en)
*
1992-01-09
1992-02-26
Nycomed As
Improvements in or relating to contrast agents
GB9200387D0
(en)
*
1992-01-09
1992-02-26
Nycomed As
Improvements in or relating to contrast agents
GB9200391D0
(en)
*
1992-01-09
1992-02-26
Nycomed As
Improvements in or relating to contrast agents
IL104084A
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1992-01-24
1996-09-12
Bracco Int Bv
Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
ES2068151B1
(en)
1993-06-23
1995-11-16
Cabrera Garrido Juan
INJECTABLE MICROS FOAM FOR SCLEROSIS.
WO1995003835A1
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1993-07-30
1995-02-09
Alliance Pharmaceutical Corp.
Stabilized microbubble compositions for ultrasound
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1993-07-30
1998-08-25
Alliance Pharmaceutical Corp.
Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
ATE234638T1
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1993-12-15
2003-04-15
Bracco Research Sa
GAS MIXTURES USABLE AS ULTRASONIC CONTRAST AGENTS
DE4406474A1
(en)
*
1994-02-23
1995-08-24
Schering Ag
Gas-containing microparticles, agents containing them, their use in ultrasound diagnostics, and methods for producing the particles and agents
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1994-09-28
1996-07-30
Alliance Pharmaceutical Corp.
Harmonic ultrasound imaging with microbubbles
DE19510690A1
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1995-03-14
1996-09-19
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Polymeric nano- and / or microparticles, processes for their production, and use in medical diagnostics and therapy
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1995-06-07
1998-09-08
Alliance Pharmaceutical Corp.
Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
DE19602930A1
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1996-01-18
1997-07-24
Schering Ag
Porous matrices made of low molecular weight substances for the generation of stable gas bubble suspensions, their use as ultrasound contrast agents and processes for their production
DE19813174A1
(en)
*
1998-03-25
1999-05-27
Schering Ag
Gas-filled microparticles, used for administering biologically active substances
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1998-10-12
2000-04-20
Mallinckrodt Inc.
Novel ultrasound contrast agents
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Btg Int Ltd
Generation of microfoam
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Bracco Suisse SA
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Method for improved measurement of local physical parameters in afluid-filled cavity
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Injectables in foam, new pharmaceutical applications
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2002-03-01
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Dyax Corp.
Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
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2002-03-01
2007-05-01
Bracco International B.V.
Multivalent constructs for therapeutic and diagnostic applications
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2014-10-13
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KDR and VEGF / KDR binding peptides and their use in diagnosis
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2002-03-01
2007-08-28
Bracco International Bv
Multivalent constructs for therapeutic and diagnostic applications
US7462366B2
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2008-12-09
Boston Scientific Scimed, Inc.
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2003-08-08
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Boston Scientific Scimed, Inc.
Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
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2011-09-06
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Mixing and delivery of therapeutic compositions
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ダイアックス、コープ
Peptides that specifically bind the HGF receptor (cMet) and uses thereof
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* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0052575A2
(en)
*
1980-11-17
1982-05-26
Schering Aktiengesellschaft
Composition generating microbubbles
AU8916382A
(en)
*
1981-10-16
1983-04-21
Schering Aktiengesellschaft
Contrast medium for ultrasonic diagnosis
AU2680584A
(en)
*
1983-04-15
1984-10-18
Schering Aktiengesellschaft
Ultrasound contrast agent containing microparticles and gas micro-bubbles
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Assignee
Title
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(en)
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Wisconsin Alumni Research Foundation
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Method of determining pressure within liquid containing vessel
1983
1983-04-15
DE
DE3313947A
patent/DE3313947A1/en
not_active
Withdrawn
1984
1984-02-20
DK
DK079084A
patent/DK165622C/en
not_active
IP Right Cessation
1984-04-05
IE
IE836/84A
patent/IE57197B1/en
not_active
IP Right Cessation
1984-04-11
CA
CA000451729A
patent/CA1232837A/en
not_active
Expired
1984-04-12
FI
FI841463A
patent/FI81265C/en
not_active
IP Right Cessation
1984-04-12
JP
JP59071940A
patent/JPS59205329A/en
active
Granted
1984-04-13
ZA
ZA842800A
patent/ZA842800B/en
unknown
1984-04-13
EP
EP84104211A
patent/EP0123235B1/en
not_active
Expired
1984-04-13
AT
AT84104211T
patent/ATE36959T1/en
not_active
IP Right Cessation
1984-04-13
NZ
NZ207854A
patent/NZ207854A/en
unknown
1984-04-13
DE
DE8484104211T
patent/DE3473829D1/en
not_active
Expired
1984-04-13
AU
AU26806/84A
patent/AU569072B2/en
not_active
Ceased
1984-04-13
NO
NO841490A
patent/NO163669C/en
not_active
IP Right Cessation
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Assignee
Title
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(en)
*
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1982-05-26
Schering Aktiengesellschaft
Composition generating microbubbles
AU8916382A
(en)
*
1981-10-16
1983-04-21
Schering Aktiengesellschaft
Contrast medium for ultrasonic diagnosis
AU2680584A
(en)
*
1983-04-15
1984-10-18
Schering Aktiengesellschaft
Ultrasound contrast agent containing microparticles and gas micro-bubbles
Also Published As
Publication number
Publication date
IE57197B1
(en)
1992-06-03
NZ207854A
(en)
1988-01-08
ATE36959T1
(en)
1988-09-15
DK165622B
(en)
1992-12-28
JPH0417164B2
(en)
1992-03-25
EP0123235B1
(en)
1988-09-07
DK79084A
(en)
1984-10-16
DK79084D0
(en)
1984-02-20
CA1232837A
(en)
1988-02-16
EP0123235A2
(en)
1984-10-31
NO163669B
(en)
1990-03-26
NO163669C
(en)
1990-07-04
DK165622C
(en)
1993-06-01
FI81265B
(en)
1990-06-29
ZA842800B
(en)
1984-11-28
DE3313947A1
(en)
1984-10-18
DE3473829D1
(en)
1988-10-13
AU2680684A
(en)
1984-10-18
NO841490L
(en)
1984-10-16
FI841463A
(en)
1984-10-16
FI81265C
(en)
1990-10-10
FI841463A0
(en)
1984-04-12
IE840836L
(en)
1984-10-15
EP0123235A3
(en)
1986-11-20
JPS59205329A
(en)
1984-11-20
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Legal Events
Date
Code
Title
Description
2003-11-13
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
