AU569097B2 – Insulin derivatives
– Google Patents
AU569097B2 – Insulin derivatives
– Google Patents
Insulin derivatives
Info
Publication number
AU569097B2
AU569097B2
AU30922/84A
AU3092284A
AU569097B2
AU 569097 B2
AU569097 B2
AU 569097B2
AU 30922/84 A
AU30922/84 A
AU 30922/84A
AU 3092284 A
AU3092284 A
AU 3092284A
AU 569097 B2
AU569097 B2
AU 569097B2
Authority
AU
Australia
Prior art keywords
insulin derivatives
insulin
derivatives
Prior art date
1983-07-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU30922/84A
Other versions
AU3092284A
(en
Inventor
Ulrich Grau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1983-07-22
Filing date
1984-07-20
Publication date
1988-01-21
1984-07-20
Application filed by Hoechst AG
filed
Critical
Hoechst AG
1985-01-24
Publication of AU3092284A
publication
Critical
patent/AU3092284A/en
1988-01-21
Application granted
granted
Critical
1988-01-21
Publication of AU569097B2
publication
Critical
patent/AU569097B2/en
2004-07-20
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
C07K14/575—Hormones
C07K14/62—Insulins
C07K14/622—Insulins at least 1 amino acid in D-form
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
C07K14/575—Hormones
C07K14/62—Insulins
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K38/00—Medicinal preparations containing peptides
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S930/00—Peptide or protein sequence
Y10S930/01—Peptide or protein sequence
Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
AU30922/84A
1983-07-22
1984-07-20
Insulin derivatives
Ceased
AU569097B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19833326472
DE3326472A1
(en)
1983-07-22
1983-07-22
NEW INSULIN DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AND PHARMACEUTICAL AGENTS FOR TREATING THE DIABETES MELLITUS
DE3326472
1983-07-22
Publications (2)
Publication Number
Publication Date
AU3092284A
AU3092284A
(en)
1985-01-24
AU569097B2
true
AU569097B2
(en)
1988-01-21
Family
ID=6204660
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU30922/84A
Ceased
AU569097B2
(en)
1983-07-22
1984-07-20
Insulin derivatives
Country Status (20)
Country
Link
US
(1)
US4701440A
(en)
EP
(1)
EP0132770B1
(en)
JP
(2)
JPS6042397A
(en)
AR
(1)
AR241864A1
(en)
AT
(1)
ATE29729T1
(en)
AU
(1)
AU569097B2
(en)
CA
(1)
CA1246548A
(en)
DE
(2)
DE3326472A1
(en)
DK
(2)
DK172211B1
(en)
ES
(2)
ES534487A0
(en)
FI
(1)
FI79854C
(en)
GR
(1)
GR81551B
(en)
HU
(1)
HUT37805A
(en)
IE
(1)
IE57709B1
(en)
IL
(1)
IL72469A
(en)
NO
(1)
NO167810C
(en)
NZ
(1)
NZ208959A
(en)
PH
(1)
PH23014A
(en)
PT
(1)
PT78940A
(en)
ZA
(1)
ZA845620B
(en)
Families Citing this family (44)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE3327928A1
(en)
*
1983-08-03
1985-02-21
Hoechst Ag, 6230 Frankfurt
METHOD FOR PRODUCING INSULIN DERIVATIVES
DE3333640A1
(en)
*
1983-09-17
1985-04-25
Hoechst Ag, 6230 Frankfurt
METHOD FOR THE PRODUCTION OF INSULIN DERIVATIVES, THE B-CHAIN C-TERMINAL EXTENDED, NEW BASICALLY MODIFIED INSULIN DERIVATIVES, THE MEANS CONTAINING THEM AND THEIR USE
DE3501641A1
(en)
*
1985-01-19
1986-07-24
Hoechst Ag, 6230 Frankfurt
METHOD FOR OBTAINING INSULIN PRECURSORS FROM REACTION MIXTURES WHICH ARE INCLUDED IN THE FOLDING OF INSULIN PRECURSORS FROM THE CORRESPONDING S-SULPHONATES
US4946828A
(en)
*
1985-03-12
1990-08-07
Novo Nordisk A/S
Novel insulin peptides
DK113585D0
(en)
*
1985-03-12
1985-03-12
Novo Industri As
NEW PEPTIDES
US4764592A
(en)
*
1987-04-23
1988-08-16
Eli Lilly And Company
Crystalline human proinsulin and process for its production
DE3717370A1
(en)
*
1987-05-22
1988-12-01
Hoechst Ag
MIXED CRYSTALS FROM INSULIN AND INSULINE DERIVATIVES, METHOD FOR THE PRODUCTION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS AND THEIR USE FOR TREATING DIABETES MELLITUS
US4789660A
(en)
*
1987-09-10
1988-12-06
American Home Products Corporation
Insulin administration using methyl and propyl paraben
DE3827533A1
(en)
*
1988-08-13
1990-02-15
Hoechst Ag
PHARMACEUTICAL PREPARATION FOR TREATING THE DIABETES MELLITUS
DE3837825A1
(en)
*
1988-11-08
1990-05-10
Hoechst Ag
NEW INSULIN DERIVATIVES, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THEM
HUT56857A
(en)
*
1988-12-23
1991-10-28
Novo Nordisk As
Human insulin analogues
US5716927A
(en)
*
1988-12-23
1998-02-10
Novo Nordisk A/S
Insulin analogs having a modified B-chain
DK134189D0
(en)
*
1989-03-20
1989-03-20
Nordisk Gentofte
INSULIN COMPOUNDS
DE3936876A1
(en)
*
1989-11-06
1991-05-23
Hoechst Ag
NEW INSULINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THE SAME
WO1992010284A2
(en)
1990-12-07
1992-06-25
Cnc Development, Inc.
Catalytic chemical reactor
YU66892A
(en)
*
1991-08-20
1995-10-24
Hoechst Ag.
PHOSPHOINOSYTOLGLICAN – A PEPTID WITH ACTION AS INSULIN
ZA928916B
(en)
*
1991-11-26
1994-05-18
Lilly Co Eli
Tri-arginine insulins
DE59209745D1
(en)
*
1991-11-29
1999-10-21
Hoechst Ag
Peptides with an insulin-like effect
US5504188A
(en)
*
1994-06-16
1996-04-02
Eli Lilly And Company
Preparation of stable zinc insulin analog crystals
DE59711533D1
(en)
1996-07-26
2004-05-27
Aventis Pharma Gmbh
Insulin derivatives with increased zinc binding
DE19649350A1
(en)
*
1996-11-28
1998-06-04
Hoechst Ag
Inositol glycans with an insulin-like effect
US6444641B1
(en)
1997-10-24
2002-09-03
Eli Lilly Company
Fatty acid-acylated insulin analogs
DE19825447A1
(en)
1998-06-06
1999-12-09
Hoechst Marion Roussel De Gmbh
New insulin analogues with increased zinc formation
WO2000075365A2
(en)
1999-06-08
2000-12-14
University Of Iowa Research Foundation
Compounds and methods to enhance raav transduction
US6852694B2
(en)
2001-02-21
2005-02-08
Medtronic Minimed, Inc.
Stabilized insulin formulations
WO2002066385A1
(en)
*
2001-02-21
2002-08-29
Seiwa Pro Co., Ltd.
Remover for scale deposited on titanium material
DE10114178A1
(en)
2001-03-23
2002-10-10
Aventis Pharma Gmbh
Zinc-free and low-zinc insulin preparations with improved stability
DE10227232A1
(en)
*
2002-06-18
2004-01-15
Aventis Pharma Deutschland Gmbh
Sour insulin preparations with improved stability
WO2004090145A2
(en)
2003-03-31
2004-10-21
University Of Iowa Research Foundation
Compounds and methods to enhance raav transduction
WO2004104026A1
(en)
*
2003-05-21
2004-12-02
Biotech Tools S.A.
Peptide complex
US7833513B2
(en)
2004-12-03
2010-11-16
Rhode Island Hospital
Treatment of Alzheimer’s Disease
CR20170369A
(en)
2008-10-17
2017-11-01
Sanofi Aventis Deutschland
COMBINATION OF AN INSULIN AND A GLP-1 AGONIST (Divisional 2011-0188)
JP5973918B2
(en)
2009-11-13
2016-08-23
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Pharmaceutical composition comprising a GLP-1 agonist and methionine
CN102711805A
(en)
2009-11-13
2012-10-03
赛诺菲-安万特德国有限公司
Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
CA2809321C
(en)
2010-08-30
2018-08-14
Sanofi-Aventis Deutschland Gmbh
Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2
(en)
2011-05-13
2017-11-21
Sanofi-Aventis Deutschland Gmbh
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
ES2550357T3
(en)
2011-08-29
2015-11-06
Sanofi-Aventis Deutschland Gmbh
Pharmaceutical combination for use in glycemic control in type 2 diabetes patients
TWI559929B
(en)
2011-09-01
2016-12-01
Sanofi Aventis Deutschland
Pharmaceutical composition for use in the treatment of a neurodegenerative disease
FI3229828T3
(en)
2014-12-12
2023-05-29
Sanofi Aventis Deutschland
Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B
(en)
2015-03-13
2021-12-11
德商賽諾菲阿凡提斯德意志有限公司
Treatment type 2 diabetes mellitus patients
TW201705975A
(en)
2015-03-18
2017-02-16
賽諾菲阿凡提斯德意志有限公司
Treatment of type 2 diabetes mellitus patients
WO2017139381A1
(en)
2016-02-08
2017-08-17
University Of Iowa Research Foundation
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
AU2017229347A1
(en)
2016-03-07
2018-11-01
University Of Iowa Research Foundation
AAV-mediated expression using a synthetic promoter and enhancer
CN113164764A
(en)
2018-09-19
2021-07-23
兹洛有限公司
Glucose-sensitive insulin and use thereof
Citations (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU3146084A
(en)
*
1983-08-03
1985-02-07
Hoechst A.G.
Preparation of insulin derivatives
AU3307284A
(en)
*
1983-09-17
1985-03-21
Hoechst Aktiengesellschaft
Preparation of insulm derivatives, the b chain of which is lengthened c-terminally
AU3341984A
(en)
*
1983-09-23
1985-03-28
Hoechst A.G.
Insulin derivatives modified in the b30 position
Family Cites Families (7)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE2256215C3
(en)
*
1972-11-16
1981-01-08
Hoechst Ag, 6000 Frankfurt
Insulin preparation containing crystalline insulin and amorphous desphenylalanine8 ‘-insulin
DE2460753A1
(en)
*
1974-12-21
1976-06-24
Hoechst Ag
METHOD FOR MANUFACTURING HUMAN INSULIN
DK146482C
(en)
*
1979-04-13
1986-10-06
Shionogi & Co
METHOD FOR PREPARING A B30-THREONINE INSULIN
DK319780A
(en)
*
1980-07-24
1982-01-25
Forenede Bryggerier As
PROCEDURE FOR ENZYMATIC REPLACEMENT OF B-30 AMINO ACID IN INSULINES
DE3209184A1
(en)
*
1982-03-13
1983-09-15
Hoechst Ag, 6230 Frankfurt
METHOD FOR CONVERTING PRAEPROINSULIN ANALOGS TO INSULINES
NL8201650A
(en)
*
1982-04-21
1983-11-16
Akzo Nv
SEMISYNTHETIC PREPARATION OF HUMANE INSULIN.
JPH118546A
(en)
*
1997-04-24
1999-01-12
Hitachi Ltd
Cmos circuit
1983
1983-07-22
DE
DE19833326472
patent/DE3326472A1/en
not_active
Withdrawn
1984
1984-07-16
HU
HU842766A
patent/HUT37805A/en
unknown
1984-07-17
AR
AR84297267A
patent/AR241864A1/en
active
1984-07-18
DE
DE8484108442T
patent/DE3466227D1/en
not_active
Expired
1984-07-18
AT
AT84108442T
patent/ATE29729T1/en
not_active
IP Right Cessation
1984-07-18
EP
EP84108442A
patent/EP0132770B1/en
not_active
Expired
1984-07-18
GR
GR75343A
patent/GR81551B/el
unknown
1984-07-19
PT
PT78940A
patent/PT78940A/en
not_active
IP Right Cessation
1984-07-19
FI
FI842914A
patent/FI79854C/en
not_active
IP Right Cessation
1984-07-20
AU
AU30922/84A
patent/AU569097B2/en
not_active
Ceased
1984-07-20
NO
NO842977A
patent/NO167810C/en
not_active
IP Right Cessation
1984-07-20
NZ
NZ208959A
patent/NZ208959A/en
unknown
1984-07-20
DK
DK358284A
patent/DK172211B1/en
not_active
IP Right Cessation
1984-07-20
JP
JP59149784A
patent/JPS6042397A/en
active
Granted
1984-07-20
ES
ES534487A
patent/ES534487A0/en
active
Granted
1984-07-20
IE
IE1889/84A
patent/IE57709B1/en
not_active
IP Right Cessation
1984-07-20
ZA
ZA845620A
patent/ZA845620B/en
unknown
1984-07-20
CA
CA000459386A
patent/CA1246548A/en
not_active
Expired
1984-07-20
PH
PH31009A
patent/PH23014A/en
unknown
1984-07-20
IL
IL72469A
patent/IL72469A/en
not_active
IP Right Cessation
1984-09-06
ES
ES535706A
patent/ES8505646A1/en
not_active
Expired
1986
1986-06-06
US
US06/873,456
patent/US4701440A/en
not_active
Expired – Lifetime
1989
1989-02-22
JP
JP1040427A
patent/JPH01294634A/en
active
Granted
1990
1990-01-04
DK
DK001790A
patent/DK172209B1/en
not_active
IP Right Cessation
Patent Citations (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU3146084A
(en)
*
1983-08-03
1985-02-07
Hoechst A.G.
Preparation of insulin derivatives
AU3307284A
(en)
*
1983-09-17
1985-03-21
Hoechst Aktiengesellschaft
Preparation of insulm derivatives, the b chain of which is lengthened c-terminally
AU3341984A
(en)
*
1983-09-23
1985-03-28
Hoechst A.G.
Insulin derivatives modified in the b30 position
Also Published As
Publication number
Publication date
DK1790A
(en)
1990-01-04
IE57709B1
(en)
1993-03-10
NO842977L
(en)
1985-01-23
JPH01294634A
(en)
1989-11-28
PH23014A
(en)
1989-03-03
GR81551B
(en)
1984-12-11
JPH052654B2
(en)
1993-01-13
FI842914A0
(en)
1984-07-19
FI79854B
(en)
1989-11-30
ATE29729T1
(en)
1987-10-15
HUT37805A
(en)
1986-02-28
NO167810B
(en)
1991-09-02
DK358284A
(en)
1985-01-23
FI842914A
(en)
1985-01-23
ES8504678A1
(en)
1985-04-16
DE3326472A1
(en)
1985-02-14
EP0132770B1
(en)
1987-09-16
DK1790D0
(en)
1990-01-04
ES535706A0
(en)
1985-06-01
DK172211B1
(en)
1998-01-05
JPH0357119B2
(en)
1991-08-30
PT78940A
(en)
1984-08-01
NO167810C
(en)
1991-12-18
DK358284D0
(en)
1984-07-20
ES534487A0
(en)
1985-04-16
US4701440A
(en)
1987-10-20
DE3466227D1
(en)
1987-10-22
IL72469A
(en)
1989-07-31
ZA845620B
(en)
1985-02-27
DK172209B1
(en)
1998-01-05
ES8505646A1
(en)
1985-06-01
NZ208959A
(en)
1989-02-24
AR241864A1
(en)
1993-01-29
EP0132770A1
(en)
1985-02-13
FI79854C
(en)
1990-03-12
IE841889L
(en)
1985-01-22
JPS6042397A
(en)
1985-03-06
AU3092284A
(en)
1985-01-24
IL72469A0
(en)
1984-11-30
CA1246548A
(en)
1988-12-13
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Legal Events
Date
Code
Title
Description
2003-02-20
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
