AU574926B2

AU574926B2 – Anti-cancer treatment using imidazolyl or pyridyl alkoxyphenoxydimethylalkanoates
– Google Patents

AU574926B2 – Anti-cancer treatment using imidazolyl or pyridyl alkoxyphenoxydimethylalkanoates
– Google Patents
Anti-cancer treatment using imidazolyl or pyridyl alkoxyphenoxydimethylalkanoates

Info

Publication number
AU574926B2

AU574926B2
AU59305/86A
AU5930586A
AU574926B2
AU 574926 B2
AU574926 B2
AU 574926B2
AU 59305/86 A
AU59305/86 A
AU 59305/86A
AU 5930586 A
AU5930586 A
AU 5930586A
AU 574926 B2
AU574926 B2
AU 574926B2
Authority
AU
Australia
Prior art keywords
alkoxyphenoxydimethylalkanoates
imidazolyl
pyridyl
cancer treatment
cancer
Prior art date
1985-06-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU59305/86A
Other versions

AU5930586A
(en

Inventor
Yoso Numasaki
Isao Ohata
Koichiro Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Yamanouchi Pharmaceutical Co Ltd

Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-06-26
Filing date
1986-06-26
Publication date
1988-07-14

1986-06-26
Application filed by Yamanouchi Pharmaceutical Co Ltd
filed
Critical
Yamanouchi Pharmaceutical Co Ltd

1987-01-08
Publication of AU5930586A
publication
Critical
patent/AU5930586A/en

1988-07-14
Application granted
granted
Critical

1988-07-14
Publication of AU574926B2
publication
Critical
patent/AU574926B2/en

2006-06-26
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members

C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D213/62—Oxygen or sulfur atoms

C07D213/63—One oxygen atom

C07D213/64—One oxygen atom attached in position 2 or 6

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole

A61K31/415—1,2-Diazoles

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom

A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P35/00—Antineoplastic agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members

C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D213/62—Oxygen or sulfur atoms

C07D213/63—One oxygen atom

C07D213/65—One oxygen atom attached in position 3 or 5

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings

C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings

C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

AU59305/86A
1985-06-26
1986-06-26
Anti-cancer treatment using imidazolyl or pyridyl alkoxyphenoxydimethylalkanoates

Ceased

AU574926B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

JP60-140901

1985-06-26

JP14090185

1985-06-26

Publications (2)

Publication Number
Publication Date

AU5930586A

AU5930586A
(en)

1987-01-08

AU574926B2
true

AU574926B2
(en)

1988-07-14

Family
ID=15279431
Family Applications (2)

Application Number
Title
Priority Date
Filing Date

AU59128/86A
Withdrawn

AU5912886A
(en)

1985-06-26
1986-06-20
Tumor treatment in warm-blooded animals

AU59305/86A
Ceased

AU574926B2
(en)

1985-06-26
1986-06-26
Anti-cancer treatment using imidazolyl or pyridyl alkoxyphenoxydimethylalkanoates

Family Applications Before (1)

Application Number
Title
Priority Date
Filing Date

AU59128/86A
Withdrawn

AU5912886A
(en)

1985-06-26
1986-06-20
Tumor treatment in warm-blooded animals

Country Status (4)

Country
Link

US
(2)

US4758580A
(en)

EP
(1)

EP0210753A3
(en)

JP
(1)

JPS6289618A
(en)

AU
(2)

AU5912886A
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU604034B2
(en)

*

1986-07-24
1990-12-06
Yamanouchi Pharmaceutical Co., Ltd.
Novel phenoxy derivatives, their preparation and pharmaceutical composition containing them

Families Citing this family (11)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4758580A
(en)

*

1985-06-26
1988-07-19
Yamanouchi Pharmaceutical Co., Ltd.
Inhibiting growth of tumors with certain substituted phenoxy dimethyl alkanoic acids, esters or salts

US5389366A
(en)

*

1986-09-19
1995-02-14
Yamanouchi Pharmaceutical Co., Ltd.
Neocarzinostatin derivative composition for oral administration

US4851423A
(en)

*

1986-12-10
1989-07-25
Schering Corporation
Pharmaceutically active compounds

US5750532A
(en)

*

1986-12-10
1998-05-12
Schering Corporation
Pharmaceutically active compounds

WO1991000858A1
(en)

*

1989-07-07
1991-01-24
Schering Corporation
Pharmaceutically active compounds

US5633274A
(en)

*

1993-02-18
1997-05-27
President And Fellows Of Harvard College
Cancer treatments

US5512591A
(en)

*

1993-02-18
1996-04-30
President And Fellows Of Harvard College
Treatments for diseases characterized by neovascularization

US5556871A
(en)

*

1995-04-24
1996-09-17
President & Fellows Of Harvard College
Method for treating epithelial precancerous lesions with topical inidazoles

EP0986393B1
(en)

*

1997-05-27
2004-03-24
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
The use of a nitroxide or a prodrug thereof in the prophylactic and therapeutic treatment of cancer

JP4912875B2
(en)

*

2004-02-27
2012-04-11
不二製油株式会社

Composition for inhibiting cancer metastasis

AU2008263931A1
(en)

*

2007-06-13
2008-12-18
Ge Healthcare Bio-Sciences Corp
Polymerase stabilization

Family Cites Families (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS5951943B2
(en)

*

1978-08-21
1984-12-17
キツセイ薬品工業株式会社

Novel imidazole derivative

ES533668A0
(en)

*

1983-06-24
1985-10-01
Yamanouchi Pharma Co Ltd

A PHENOXI COMPOUND

JPS6013761A
(en)

*

1983-07-05
1985-01-24
Yamanouchi Pharmaceut Co Ltd
Novel pyridyl ether derivative

US4758580A
(en)

*

1985-06-26
1988-07-19
Yamanouchi Pharmaceutical Co., Ltd.
Inhibiting growth of tumors with certain substituted phenoxy dimethyl alkanoic acids, esters or salts

1986

1986-06-16
US
US06/874,547
patent/US4758580A/en
not_active
Expired – Fee Related

1986-06-20
AU
AU59128/86A
patent/AU5912886A/en
not_active
Withdrawn

1986-06-25
JP
JP61150078A
patent/JPS6289618A/en
active
Granted

1986-06-26
AU
AU59305/86A
patent/AU574926B2/en
not_active
Ceased

1986-06-26
EP
EP86304966A
patent/EP0210753A3/en
not_active
Ceased

1988

1988-05-24
US
US07/198,099
patent/US4886818A/en
not_active
Expired – Fee Related

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU604034B2
(en)

*

1986-07-24
1990-12-06
Yamanouchi Pharmaceutical Co., Ltd.
Novel phenoxy derivatives, their preparation and pharmaceutical composition containing them

Also Published As

Publication number
Publication date

EP0210753A3
(en)

1989-02-08

EP0210753A2
(en)

1987-02-04

US4886818A
(en)

1989-12-12

AU5930586A
(en)

1987-01-08

US4758580A
(en)

1988-07-19

JPS6289618A
(en)

1987-04-24

AU5912886A
(en)

1987-01-08

JPH0244810B2
(en)

1990-10-05

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