AU589371B2 – Purine derivatives and use as therapeutic agent
– Google Patents
AU589371B2 – Purine derivatives and use as therapeutic agent
– Google Patents
Purine derivatives and use as therapeutic agent
Info
Publication number
AU589371B2
AU589371B2
AU47560/85A
AU4756085A
AU589371B2
AU 589371 B2
AU589371 B2
AU 589371B2
AU 47560/85 A
AU47560/85 A
AU 47560/85A
AU 4756085 A
AU4756085 A
AU 4756085A
AU 589371 B2
AU589371 B2
AU 589371B2
Authority
AU
Australia
Prior art keywords
therapeutic agent
purine derivatives
purine
derivatives
therapeutic
Prior art date
1984-09-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires 2010-05-16
Application number
AU47560/85A
Other versions
AU4756085A
(en
Inventor
Michael Raymond Harnden
Richard Lewis Jarvest
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis International Pharmaceutical Ltd
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1984-09-20
Filing date
1985-09-18
Publication date
1989-10-12
1984-09-20
Priority claimed from GB848423833A
external-priority
patent/GB8423833D0/en
1985-04-23
Priority claimed from GB858510331A
external-priority
patent/GB8510331D0/en
1985-08-16
Priority claimed from GB858520618A
external-priority
patent/GB8520618D0/en
1985-09-18
Application filed by Beecham Group PLC
filed
Critical
Beecham Group PLC
1986-03-27
Publication of AU4756085A
publication
Critical
patent/AU4756085A/en
1989-10-12
Application granted
granted
Critical
1989-10-12
Publication of AU589371B2
publication
Critical
patent/AU589371B2/en
2001-11-15
Assigned to NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD
reassignment
NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD
Alteration of Name(s) in Register under S187
Assignors: BEECHAM GROUP PLC
2010-05-16
Adjusted expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D473/00—Heterocyclic compounds containing purine ring systems
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/12—Antivirals
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/12—Antivirals
A61P31/20—Antivirals for DNA viruses
A61P31/22—Antivirals for DNA viruses for herpes viruses
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
C07F9/02—Phosphorus compounds
C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
AU47560/85A
1984-09-20
1985-09-18
Purine derivatives and use as therapeutic agent
Expired
AU589371B2
(en)
Applications Claiming Priority (6)
Application Number
Priority Date
Filing Date
Title
GB848423833A
GB8423833D0
(en)
1984-09-20
1984-09-20
Compounds
GB8423833
1984-09-20
GB8510331
1985-04-23
GB858510331A
GB8510331D0
(en)
1985-04-23
1985-04-23
Compounds
GB858520618A
GB8520618D0
(en)
1985-08-16
1985-08-16
Compounds
GB8520618
1985-08-16
Publications (2)
Publication Number
Publication Date
AU4756085A
AU4756085A
(en)
1986-03-27
AU589371B2
true
AU589371B2
(en)
1989-10-12
Family
ID=27262464
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU47560/85A
Expired
AU589371B2
(en)
1984-09-20
1985-09-18
Purine derivatives and use as therapeutic agent
Country Status (24)
Country
Link
EP
(1)
EP0182024B1
(en)
JP
(2)
JPS6185388A
(en)
KR
(1)
KR930006349B1
(en)
AT
(1)
AT389118B
(en)
AU
(1)
AU589371B2
(en)
BG
(1)
BG61493B2
(en)
CA
(1)
CA1262899A
(en)
CY
(1)
CY1747A
(en)
CZ
(1)
CZ283721B6
(en)
DE
(1)
DE3582399D1
(en)
DK
(1)
DK167019B1
(en)
ES
(1)
ES8703876A1
(en)
FI
(1)
FI87564C
(en)
GR
(1)
GR852272B
(en)
HK
(1)
HK128693A
(en)
HU
(1)
HU198934B
(en)
IE
(1)
IE58141B1
(en)
MX
(1)
MX165116B
(en)
MY
(1)
MY102473A
(en)
NL
(1)
NL960006I2
(en)
NO
(1)
NO167572C
(en)
NZ
(1)
NZ213528A
(en)
PT
(1)
PT81160B
(en)
WO
(1)
WO1987005604A1
(en)
Families Citing this family (44)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
SE8406538D0
(en)
*
1984-12-21
1984-12-21
Astra Laekemedel Ab
NOVEL DERIVATIVES OF PURINE
GB8628826D0
(en)
*
1986-12-02
1987-01-07
Beecham Group Plc
Pharmaceutical products
DE3855774T2
(en)
*
1987-08-01
1997-06-12
Beecham Group Plc
Purine compounds and their production
US5175288A
(en)
*
1987-08-01
1992-12-29
Beecham Group P.L.C.
Process for preparing purine derivatives and intermediates thereof
GB8817270D0
(en)
*
1988-07-20
1988-08-24
Beecham Group Plc
Novel process
GB8817607D0
(en)
*
1988-07-23
1988-09-01
Beecham Group Plc
Novel process
GB8822236D0
(en)
*
1988-09-21
1988-10-26
Beecham Group Plc
Chemical process
CA2009109A1
(en)
*
1989-02-02
1990-08-02
John Hannah
Antiviral acyclonucleosides and acyclonucleotides
JPH02247191A
(en)
*
1989-02-02
1990-10-02
Merck & Co Inc
Cyclic monophosphates of purine and pyrimidine noncyclic nucleoside as antiretroviral agent
GB8904855D0
(en)
*
1989-03-03
1989-04-12
Beecham Group Plc
Pharmaceutical treatment
GB8922076D0
(en)
*
1989-09-28
1989-11-15
Beecham Group Plc
Novel process
GB9004647D0
(en)
*
1990-03-01
1990-04-25
Beecham Group Plc
Pharmaceuticals
GB9102127D0
(en)
*
1991-01-31
1991-03-13
Smithkline Beecham Plc
Pharmaceuticals
GB9201961D0
(en)
1992-01-30
1992-03-18
Smithkline Beecham Plc
Pharmaceuticals
IL111138A
(en)
*
1993-10-05
1997-04-15
Smithkline Beecham Plc
Pharmaceutical compositions comprising penciclovir and/or its bioprecursor and/or its derivatives for the treatment and prophylaxis of post-herpetic neuralgia
GB9326177D0
(en)
*
1993-12-22
1994-02-23
Smithkline Beecham Plc
Pharmaceuticals
US6124304A
(en)
*
1993-10-05
2000-09-26
Smithkline Beecham Plc
Penciclovir for the treatment of zoster associated pain
US6683084B1
(en)
1993-11-12
2004-01-27
Novartis International Pharmaceutical Ltd.
Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 6 infections
GB9323404D0
(en)
*
1993-11-12
1994-01-05
Smithkline Beecham Plc
Pharmaceuticals
GB9323403D0
(en)
*
1993-11-12
1994-01-05
Smithkline Beecham Plc
Pharmaceuticals
GB9402161D0
(en)
1994-02-04
1994-03-30
Wellcome Found
Chloropyrimidine intermediates
GB9407698D0
(en)
1994-04-19
1994-06-15
Smithkline Beecham Plc
Pharmaceuticals
DE4420751A1
(en)
*
1994-06-15
1995-12-21
Basf Ag
Process for the preparation of enantiomerically pure lactams
HUT77436A
(en)
*
1994-10-05
1998-04-28
Darwin Discovery Limited
Purine and guanine compounds, process for producing them, pharmaceutical compositions containing them and their use for producing pharmaceutical compositions
GB9504497D0
(en)
1995-03-07
1995-04-26
Smithkline Beecham Plc
Pharmaceuticals
GB9600847D0
(en)
1996-01-16
1996-03-20
Smithkline Beecham Plc
Pharmaceuticals
US7279483B2
(en)
1996-02-07
2007-10-09
Novartis Ag
Famciclovir monohydrate
EP0885223B1
(en)
*
1996-02-07
2001-09-19
Novartis International Pharmaceutical Ltd.
Pharmaceutical compositions comprising famciclovir monohydrate
GB9615276D0
(en)
*
1996-07-20
1996-09-04
Smithkline Beecham Plc
Pharmaceuticals
GB9615253D0
(en)
*
1996-07-20
1996-09-04
Smithkline Beecham Plc
Pharmaceuticals
PT102030B
(en)
*
1996-07-20
1999-04-30
Smithkline Beecham Plc
PROCESS FOR THE PRESENTATION OF PENCICLOVIR OR FAMCICLOVIR COMPOUNDS WHICH IS UTESI AS ANTI-AGING AGENTS
CA2251481A1
(en)
*
1997-11-12
1999-05-12
Junichi Yasuoka
Purine derivatives having cyclopropane ring
GB9807116D0
(en)
1998-04-02
1998-06-03
Smithkline Beecham Plc
Novel process
SI20022A
(en)
*
1998-07-29
2000-02-29
Kemijski inštitut
Alkyl substituted purine derivatives and their preparation
KR20040088519A
(en)
2002-02-22
2004-10-16
뉴 리버 파마슈티칼스, 인크.
Active Agent Delivery Systems and Methods for Protecting and Administering Active Agents
US20040097528A1
(en)
2002-08-26
2004-05-20
Ben-Zion Dolitzky
Crystalline solid famciclovir forms I, II, III and preparation thereof
WO2004064845A1
(en)
2003-01-14
2004-08-05
Gilead Sciences, Inc.
Compositions and methods for combination antiviral therapy
AU2006230269A1
(en)
2005-03-30
2006-10-05
Novartis Ag
Penciclovir or famciclovir for the treatment of recurrent genital herpes with a one-day application
GB2426247A
(en)
*
2005-05-20
2006-11-22
Arrow Int Ltd
Methods of preparing purine derivatives such as famciclovir
TWI471145B
(en)
2005-06-13
2015-02-01
Bristol Myers Squibb & Gilead Sciences Llc
Unitary pharmaceutical dosage form
TWI375560B
(en)
2005-06-13
2012-11-01
Gilead Sciences Inc
Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
WO2017029298A1
(en)
2015-08-17
2017-02-23
Sanovel Ilac Sanayi Ve Ticaret A.S.
A topical antiviral composition
JP2019504000A
(en)
*
2015-12-08
2019-02-14
レトロフィン， インコーポレイテッド
Cyclic phosphates and cyclic phosphoramidates for the treatment of neurological disorders
WO2021209563A1
(en)
2020-04-16
2021-10-21
Som Innovation Biotech, S.A.
Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
Citations (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU3197384A
(en)
*
1983-08-18
1985-02-21
Novartis International Pharmaceutical Ltd
9-substituted-2-amino purines
EP0152316A1
(en)
*
1984-01-26
1985-08-21
Merck & Co. Inc.
Substituted butyl guanines and their utilization in antiviral compositions
Family Cites Families (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS5989682A
(en)
*
1982-10-14
1984-05-23
ザ・ウエルカム・フアウンデ−シヨン
Purine derivatives, manufacture and medicine
DE3485225D1
(en)
*
1983-08-18
1991-12-05
Beecham Group Plc
ANTIVIRAL GUANINE DERIVATIVES.
1985
1985-09-09
EP
EP85111354A
patent/EP0182024B1/en
not_active
Expired – Lifetime
1985-09-09
DE
DE8585111354T
patent/DE3582399D1/en
not_active
Expired – Lifetime
1985-09-18
PT
PT81160A
patent/PT81160B/en
unknown
1985-09-18
AU
AU47560/85A
patent/AU589371B2/en
not_active
Expired
1985-09-18
DK
DK424685A
patent/DK167019B1/en
not_active
IP Right Cessation
1985-09-18
GR
GR852272A
patent/GR852272B/el
unknown
1985-09-18
IE
IE230785A
patent/IE58141B1/en
not_active
IP Right Cessation
1985-09-18
NZ
NZ213528A
patent/NZ213528A/en
unknown
1985-09-18
CA
CA000491028A
patent/CA1262899A/en
not_active
Expired
1985-09-19
JP
JP60207693A
patent/JPS6185388A/en
active
Granted
1985-09-19
ES
ES547128A
patent/ES8703876A1/en
not_active
Expired
1985-10-01
MX
MX9010A
patent/MX165116B/en
unknown
1986
1986-03-17
AT
AT0904286A
patent/AT389118B/en
not_active
IP Right Cessation
1986-03-17
WO
PCT/GB1986/000153
patent/WO1987005604A1/en
active
IP Right Grant
1986-03-17
HU
HU863048A
patent/HU198934B/en
unknown
1986-03-17
KR
KR1019870701056A
patent/KR930006349B1/en
not_active
IP Right Cessation
1987
1987-09-29
MY
MYPI87002221A
patent/MY102473A/en
unknown
1987-11-16
FI
FI875059A
patent/FI87564C/en
not_active
IP Right Cessation
1987-11-16
NO
NO87874764A
patent/NO167572C/en
unknown
1991
1991-12-19
CZ
CS913915A
patent/CZ283721B6/en
not_active
IP Right Cessation
1993
1993-05-07
JP
JP5130044A
patent/JPH0826021B2/en
not_active
Expired – Lifetime
1993-11-10
BG
BG98209A
patent/BG61493B2/en
unknown
1993-11-18
HK
HK1286/93A
patent/HK128693A/en
not_active
IP Right Cessation
1994
1994-06-03
CY
CY174794A
patent/CY1747A/en
unknown
1996
1996-04-09
NL
NL960006C
patent/NL960006I2/en
unknown
Patent Citations (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU3197384A
(en)
*
1983-08-18
1985-02-21
Novartis International Pharmaceutical Ltd
9-substituted-2-amino purines
EP0152316A1
(en)
*
1984-01-26
1985-08-21
Merck & Co. Inc.
Substituted butyl guanines and their utilization in antiviral compositions
Also Published As
Publication number
Publication date
MX165116B
(en)
1992-10-27
EP0182024A3
(en)
1989-03-08
PT81160A
(en)
1985-10-01
DK167019B1
(en)
1993-08-16
ES8703876A1
(en)
1987-03-01
AT389118B
(en)
1989-10-25
JPS6185388A
(en)
1986-04-30
NO167572C
(en)
1991-11-20
HK128693A
(en)
1993-11-26
KR930006349B1
(en)
1993-07-14
IE58141B1
(en)
1993-07-14
CZ283721B6
(en)
1998-06-17
NZ213528A
(en)
1989-03-29
HUT47576A
(en)
1989-03-28
DK424685D0
(en)
1985-09-18
EP0182024A2
(en)
1986-05-28
NO874764L
(en)
1987-11-16
NL960006I1
(en)
1996-09-02
JPH0625241A
(en)
1994-02-01
FI875059A0
(en)
1987-11-16
FI87564C
(en)
1993-01-25
JPH0826021B2
(en)
1996-03-13
NO874764D0
(en)
1987-11-16
IE852307L
(en)
1986-03-20
DK424685A
(en)
1986-03-21
MY102473A
(en)
1992-06-30
AU4756085A
(en)
1986-03-27
NO167572B
(en)
1991-08-12
NL960006I2
(en)
1996-09-02
BG61493B2
(en)
1997-09-30
ATA904286A
(en)
1989-03-15
DE3582399D1
(en)
1991-05-08
PT81160B
(en)
1988-01-22
FI875059A
(en)
1987-11-16
CY1747A
(en)
1994-06-03
FI87564B
(en)
1992-10-15
WO1987005604A1
(en)
1987-09-24
JPH0586792B2
(en)
1993-12-14
HU198934B
(en)
1989-12-28
CA1262899A
(en)
1989-11-14
EP0182024B1
(en)
1991-04-03
GR852272B
(en)
1986-01-21
CS391591A3
(en)
1992-05-13
ES547128A0
(en)
1987-03-01
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Legal Events
Date
Code
Title
Description
2001-11-15
PC
Assignment registered
Owner name:
NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD
Free format text:
FORMER OWNER WAS: BEECHAM GROUP P.L.C.
