AU4783685A – Diarylacetylenes, their preparation and their use
– Google Patents
AU4783685A – Diarylacetylenes, their preparation and their use
– Google Patents
Diarylacetylenes, their preparation and their use
Info
Publication number
AU4783685A
AU4783685A
AU47836/85A
AU4783685A
AU4783685A
AU 4783685 A
AU4783685 A
AU 4783685A
AU 47836/85 A
AU47836/85 A
AU 47836/85A
AU 4783685 A
AU4783685 A
AU 4783685A
AU 4783685 A
AU4783685 A
AU 4783685A
Authority
AU
Australia
Prior art keywords
diarylacetylenes
preparation
disorders
novel
useful
Prior art date
1984-09-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU47836/85A
Other versions
AU584124B2
(en
Inventor
Fritz Frieder Frickel
Axel Nuerrenbach
Hans-Heiner Wuest
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1984-09-22
Filing date
1985-09-24
Publication date
1986-04-24
1985-09-24
Application filed by BASF SE
filed
Critical
BASF SE
1986-04-24
Publication of AU4783685A
publication
Critical
patent/AU4783685A/en
1989-05-18
Application granted
granted
Critical
1989-05-18
Publication of AU584124B2
publication
Critical
patent/AU584124B2/en
2005-09-24
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
C07D257/04—Five-membered rings
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P17/00—Drugs for dermatological disorders
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P35/00—Antineoplastic agents
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C255/00—Carboxylic acid nitriles
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C43/00—Ethers; Compounds having groups, groups or groups
C07C43/02—Ethers
C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
C07C43/14—Unsaturated ethers
C07C43/164—Unsaturated ethers containing six-membered aromatic rings
C07C43/168—Unsaturated ethers containing six-membered aromatic rings containing six-membered aromatic rings and other rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C43/00—Ethers; Compounds having groups, groups or groups
C07C43/02—Ethers
C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C47/00—Compounds having —CHO groups
C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
C07C47/548—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C47/00—Compounds having —CHO groups
C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
C07C47/57—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups polycyclic
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C47/00—Compounds having —CHO groups
C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
C07C49/757—Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
C07C49/798—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring containing rings other than six-membered aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
C07C63/74—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen having unsaturation outside the aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
C07C65/38—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups having unsaturation outside the aromatic rings
Abstract
Novel diarylacetylenes of the formula I
AU47836/85A
1984-09-22
1985-09-24
Diarylacetylenes, their preparation and their use
Ceased
AU584124B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19843434946
DE3434946A1
(en)
1984-09-22
1984-09-22
DIARYLACETYLENE, THEIR PRODUCTION AND USE
DE3434946
1984-09-22
Publications (2)
Publication Number
Publication Date
AU4783685A
true
AU4783685A
(en)
1986-04-24
AU584124B2
AU584124B2
(en)
1989-05-18
Family
ID=6246162
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU47836/85A
Ceased
AU584124B2
(en)
1984-09-22
1985-09-24
Diarylacetylenes, their preparation and their use
Country Status (12)
Country
Link
US
(3)
US4806558A
(en)
EP
(1)
EP0176034B1
(en)
JP
(1)
JPS61155340A
(en)
AT
(1)
ATE45942T1
(en)
AU
(1)
AU584124B2
(en)
CA
(1)
CA1266672A
(en)
DE
(2)
DE3434946A1
(en)
FI
(1)
FI84908C
(en)
HU
(1)
HU193816B
(en)
IL
(1)
IL76454A
(en)
NO
(1)
NO162613C
(en)
ZA
(1)
ZA857274B
(en)
Cited By (4)
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Title
US4870219A
(en)
*
1986-05-23
1989-09-26
Hoffmann-La Roche Inc.
Novel tetrahydronaphthalene and indane derivatives
US4990703A
(en)
*
1987-03-17
1991-02-05
Hoffmann-La Roche Inc.
Novel tetrahydronaphthalene and indane derivatives
US5030765A
(en)
*
1986-05-23
1991-07-09
Hoffmann-La Roche Inc.
Novel tetrahydronaphthalene and indane derivatives
US5030764A
(en)
*
1986-05-23
1991-07-09
Hoffmann-La Roche Inc.
Novel tetrahydronaphthalene and indane derivatives
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US5256694A
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*
1984-09-22
1993-10-26
Basf Aktiengesellschaft
Diarylacetylenes, their preparation and their use
DE3434946A1
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*
1984-09-22
1986-04-03
Basf Ag, 6700 Ludwigshafen
DIARYLACETYLENE, THEIR PRODUCTION AND USE
FR2605626B1
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1986-10-27
1989-06-02
Oreal
NOVEL BICYCLIC AROMATIC DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE IN COSMETICS AND IN HUMAN AND VETERINARY MEDICINE
NZ222968A
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1986-12-24
1990-05-28
Allergan Inc
Ethynylheteroaromatic derivatives and medicaments
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1987-03-05
1992-05-27
Takasago Perfumery Co. Ltd.
Perfume composition
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1987-03-13
1992-09-22
Allergan, Inc.
Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid like activity
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1987-03-20
1993-08-10
Allergan, Inc.
Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
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1987-03-20
1997-02-11
Allergan
Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
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1987-03-20
1993-11-23
Allergan, Inc.
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1992-02-18
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Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
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1987-03-26
1989-03-07
Allergan, Inc.
Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
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1987-11-11
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Merck Patent Gesellschaft Mit Beschrankter Haftung
Naphthylacetylenes
DE3903993A1
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1989-02-10
1990-08-16
Basf Ag
DIARYL SUBSTITUTED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND MEDICINAL PRODUCTS THEREOF
US5196532A
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1989-02-08
1993-03-23
Basf Aktiengesellschaft
Diaryl-substituted heterocyclic compounds, their preparation and drugs and cosmetics obtained therefrom
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1989-07-26
1991-02-12
Allergan, Inc.
Phenylethenyl compounds having retinoid-like activity
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1989-08-08
1991-02-28
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DIARYLACETYLENE, THEIR MANUFACTURE AND USE
US5053523A
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1989-09-19
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Allergan, Inc.
Ethynyl-chroman compounds
US5248777A
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1989-09-19
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Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
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Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
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Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
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1989-09-19
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Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-oxochromanyl, 2-oxothiochromanyl or 2-oxo-1,2,3,4-tetrahydro-quinolinyl group having retinoid-like biological activity
US5162546A
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1992-11-10
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Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5272156A
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1993-12-21
Allergan, Inc.
Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5175185A
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US5206217A
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US5426118A
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US5618943A
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Also Published As
Publication number
Publication date
HU193816B
(en)
1987-12-28
US4806558A
(en)
1989-02-21
NO853696L
(en)
1986-03-24
EP0176034A3
(en)
1987-09-16
NO162613B
(en)
1989-10-16
DE3434946A1
(en)
1986-04-03
FI84908C
(en)
1992-02-10
US4994489A
(en)
1991-02-19
FI84908B
(en)
1991-10-31
US5126371A
(en)
1992-06-30
EP0176034A2
(en)
1986-04-02
AU584124B2
(en)
1989-05-18
CA1266672A
(en)
1990-03-13
JPH0372210B2
(en)
1991-11-18
FI853622A0
(en)
1985-09-20
HUT39151A
(en)
1986-08-28
NO162613C
(en)
1990-01-24
DE3572653D1
(en)
1989-10-05
ATE45942T1
(en)
1989-09-15
EP0176034B1
(en)
1989-08-30
IL76454A
(en)
1989-01-31
ZA857274B
(en)
1986-05-28
JPS61155340A
(en)
1986-07-15
FI853622L
(en)
1986-03-23
IL76454A0
(en)
1986-01-31
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Patent ceased section 143(a) (annual fees not paid) or expired
