AU4815699A – Liposomal formulations of busulphan
– Google Patents
AU4815699A – Liposomal formulations of busulphan
– Google Patents
Liposomal formulations of busulphan
Info
Publication number
AU4815699A
AU4815699A
AU48156/99A
AU4815699A
AU4815699A
AU 4815699 A
AU4815699 A
AU 4815699A
AU 48156/99 A
AU48156/99 A
AU 48156/99A
AU 4815699 A
AU4815699 A
AU 4815699A
AU 4815699 A
AU4815699 A
AU 4815699A
Authority
AU
Australia
Prior art keywords
formulations
busulphan
parenteral administration
liposomal formulations
encapsulated
Prior art date
1998-06-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU48156/99A
Inventor
Moustapha Hassan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Karolinska Innovations AB
Original Assignee
Karolinska Innovations AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1998-06-18
Filing date
1999-06-17
Publication date
2000-01-05
1998-06-18
Priority claimed from SE9802197A
external-priority
patent/SE9802197D0/en
1999-06-17
Application filed by Karolinska Innovations AB
filed
Critical
Karolinska Innovations AB
2000-01-05
Publication of AU4815699A
publication
Critical
patent/AU4815699A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/10—Dispersions; Emulsions
A61K9/127—Liposomes
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P35/00—Antineoplastic agents
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Pharmaceutically acceptable liposome-encapsulated busulphan formulations for parenteral administration are provided, as well as a process for their manufacture. The formulations are stable, have improved biodistribution and significantly reduced side effects over those produced by oral administration or parenteral administration of free drug. The formulations are useful as part of bone marrow transplant conditioning regimens.
AU48156/99A
1998-06-18
1999-06-17
Liposomal formulations of busulphan
Abandoned
AU4815699A
(en)
Applications Claiming Priority (5)
Application Number
Priority Date
Filing Date
Title
US8975998P
1998-06-18
1998-06-18
SE9802197A
SE9802197D0
(en)
1998-06-18
1998-06-18
Formulations of busulphan
US60089759
1998-06-18
SE9802197
1998-06-18
PCT/SE1999/001093
WO1999065481A1
(en)
1998-06-18
1999-06-17
Liposomal formulations of busulphan
Publications (1)
Publication Number
Publication Date
AU4815699A
true
AU4815699A
(en)
2000-01-05
Family
ID=26663332
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU48156/99A
Abandoned
AU4815699A
(en)
1998-06-18
1999-06-17
Liposomal formulations of busulphan
Country Status (6)
Country
Link
EP
(1)
EP1089727B8
(en)
JP
(1)
JP2002518322A
(en)
AT
(1)
ATE311870T1
(en)
AU
(1)
AU4815699A
(en)
DE
(1)
DE69928805T2
(en)
WO
(1)
WO1999065481A1
(en)
Family Cites Families (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
CA1338702C
(en)
*
1987-03-05
1996-11-12
Lawrence D. Mayer
High drug:lipid formulations of liposomal- antineoplastic agents
WO1992022298A1
(en)
*
1991-06-18
1992-12-23
Unger Evan C
Novel liposomal drug delivery systems
EP0546951A1
(en)
*
1991-12-13
1993-06-16
The Liposome Company, Inc.
Combination of liposome encapsulated antineoplastic agents, such as doxorubicin with colony stimulating factors
US5430057A
(en)
*
1993-09-30
1995-07-04
Board Of Regents, The University Of Texas System
Parenteral busulfan for treatment of malignant disease
1999
1999-06-17
JP
JP2000554361A
patent/JP2002518322A/en
active
Pending
1999-06-17
AT
AT99931721T
patent/ATE311870T1/en
not_active
IP Right Cessation
1999-06-17
DE
DE69928805T
patent/DE69928805T2/en
not_active
Expired – Lifetime
1999-06-17
AU
AU48156/99A
patent/AU4815699A/en
not_active
Abandoned
1999-06-17
EP
EP99931721A
patent/EP1089727B8/en
not_active
Expired – Lifetime
1999-06-17
WO
PCT/SE1999/001093
patent/WO1999065481A1/en
active
IP Right Grant
Also Published As
Publication number
Publication date
EP1089727B1
(en)
2005-12-07
WO1999065481A1
(en)
1999-12-23
ATE311870T1
(en)
2005-12-15
EP1089727B8
(en)
2006-03-08
DE69928805T2
(en)
2006-08-31
JP2002518322A
(en)
2002-06-25
DE69928805D1
(en)
2006-01-12
EP1089727A1
(en)
2001-04-11
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Legal Events
Date
Code
Title
Description
2001-03-08
MK6
Application lapsed section 142(2)(f)/reg. 8.3(3) – pct applic. not entering national phase
