AU4847185A

AU4847185A – 3,5-Di-tert-butyl-4-hydroxybenzophenone imine derivatives
– Google Patents

AU4847185A – 3,5-Di-tert-butyl-4-hydroxybenzophenone imine derivatives
– Google Patents
3,5-Di-tert-butyl-4-hydroxybenzophenone imine derivatives

Info

Publication number
AU4847185A

AU4847185A
AU48471/85A
AU4847185A
AU4847185A
AU 4847185 A
AU4847185 A
AU 4847185A
AU 48471/85 A
AU48471/85 A
AU 48471/85A
AU 4847185 A
AU4847185 A
AU 4847185A
AU 4847185 A
AU4847185 A
AU 4847185A
Authority
AU
Australia
Prior art keywords
group
sup
compound
salt
hydroxybenzophenone
Prior art date
1984-10-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU48471/85A
Other versions

AU578979B2
(en

Inventor
Yukio Hasegawa
Takashi Mikami
Katsuhiko Miyasaka
Katsuhiko Miyazawa
Morinobu Saito
Michitaka Sato
Yasushi Suzuki
Norio Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aska Pharmaceutical Co Ltd

Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1984-10-19
Filing date
1985-10-10
Publication date
1986-04-24

1985-10-10
Application filed by Teikoku Hormone Manufacturing Co Ltd
filed
Critical
Teikoku Hormone Manufacturing Co Ltd

1986-04-24
Publication of AU4847185A
publication
Critical
patent/AU4847185A/en

1988-11-10
Application granted
granted
Critical

1988-11-10
Publication of AU578979B2
publication
Critical
patent/AU578979B2/en

2005-10-10
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton

C07C251/72—Hydrazones

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P25/00—Drugs for disorders of the nervous system

A61P25/04—Centrally acting analgesics, e.g. opioids

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P35/00—Antineoplastic agents

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A61P37/08—Antiallergic agents

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/08—Vasodilators for multiple indications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton

C07C251/32—Oximes

C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals

C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups

Abstract

A compound represented by the formulawherein R’ represents a hydroxyl group, an alkanoyloxy group or a group of the formulain which R2 represents a hydrogen atom or a lower alkyl group, and R3 represents a hydrogen atom, a lower alkyl group, an alkanoyl group, a phenyl group, a carbamoyl group or a thiocarbamoyl group, or a salt thereof.The said compound can be prepared by reacting a compound represented by the formulawith a compound of the formulawherein R’ is as defined hereinabove, or a salt thereof, and as required, alkanoylating the resulting compound of formula (I) in which R’ represents a hydroxyl group or an amino group, and as required, converting the resulting compound of formula (I) in which R’ is the groupinto its salt, and is useful for the treatment of inflammation, pain or rheumatism.

AU48471/85A
1984-10-19
1985-10-10
3,5-Di-tert-butyl-4-hydroxybenzophenone imine derivatives

Ceased

AU578979B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

JP59218679A

JPS61100555A
(en)

1984-10-19
1984-10-19
Benzophenone oxime derivative

JP59-218679

1984-10-19

Publications (2)

Publication Number
Publication Date

AU4847185A
true

AU4847185A
(en)

1986-04-24

AU578979B2

AU578979B2
(en)

1988-11-10

Family
ID=16723718
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU48471/85A
Ceased

AU578979B2
(en)

1984-10-19
1985-10-10
3,5-Di-tert-butyl-4-hydroxybenzophenone imine derivatives

Country Status (10)

Country
Link

US
(1)

US4673692A
(en)

EP
(1)

EP0185158B1
(en)

JP
(1)

JPS61100555A
(en)

KR
(1)

KR910002372B1
(en)

AT
(1)

ATE32216T1
(en)

AU
(1)

AU578979B2
(en)

CA
(1)

CA1253871A
(en)

DE
(1)

DE3561512D1
(en)

ES
(1)

ES8609219A1
(en)

NZ
(1)

NZ213780A
(en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS6284051A
(en)

*

1985-10-07
1987-04-17
Teikoku Hormone Mfg Co Ltd
Diphenylmethylimine derivative

DE3856315T2
(en)

*

1987-10-22
1999-10-14
Procter & Gamble

Sunscreen containing chelating agents

WO1990011619A1
(en)

*

1989-03-23
1990-10-04
Grumman Aerospace Corporation
Single trench mosfet-capacitor cell for analog signal processing

US5288896A
(en)

*

1992-01-15
1994-02-22
Warner-Lambert Company
3,5-di-t-butyl-4-hydroxylphenylmethylhydroxylamines and their derivatives, pharmaceutical compositions, and methods of use therefor

WO1994005276A1
(en)

*

1992-09-08
1994-03-17
Morgan Lee R
Cytotoxic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3925472A
(en)

*

1968-03-01
1975-12-09
Gen Mills Chem Inc
Phenolic oximes

US4124725A
(en)

*

1977-05-16
1978-11-07
Riker Laboratories, Inc.
Anti-inflammatory method

US4472435A
(en)

*

1980-07-31
1984-09-18
Hoffman-La Roche Inc.
Benzophenone derivatives useful in treating heart failure

FR2540107B1
(en)

*

1983-01-28
1986-10-17
Inst Rech Chim Biolog

NOVEL HALOGENOBENZOPHENONE-OXIME DERIVATIVES, THERAPEUTIC USE AND PREPARATION METHOD

1984

1984-10-19
JP
JP59218679A
patent/JPS61100555A/en
active
Granted

1985

1985-10-09
DE
DE8585112791T
patent/DE3561512D1/en
not_active
Expired

1985-10-09
AT
AT85112791T
patent/ATE32216T1/en
not_active
IP Right Cessation

1985-10-09
EP
EP85112791A
patent/EP0185158B1/en
not_active
Expired

1985-10-10
CA
CA000492679A
patent/CA1253871A/en
not_active
Expired

1985-10-10
NZ
NZ213780A
patent/NZ213780A/en
unknown

1985-10-10
AU
AU48471/85A
patent/AU578979B2/en
not_active
Ceased

1985-10-18
ES
ES548004A
patent/ES8609219A1/en
not_active
Expired

1985-10-18
US
US06/789,275
patent/US4673692A/en
not_active
Expired – Fee Related

1985-10-19
KR
KR1019850007727A
patent/KR910002372B1/en
not_active
IP Right Cessation

Also Published As

Publication number
Publication date

NZ213780A
(en)

1989-08-29

KR860003204A
(en)

1986-05-21

CA1253871A
(en)

1989-05-09

ES548004A0
(en)

1986-09-01

EP0185158B1
(en)

1988-01-27

ATE32216T1
(en)

1988-02-15

DE3561512D1
(en)

1988-03-03

ES8609219A1
(en)

1986-09-01

JPH0477742B2
(en)

1992-12-09

AU578979B2
(en)

1988-11-10

EP0185158A1
(en)

1986-06-25

JPS61100555A
(en)

1986-05-19

US4673692A
(en)

1987-06-16

KR910002372B1
(en)

1991-04-20

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