AU612665B2 – 3-demethyl-4-fluoromevalonic acid derivatives, a process for the preparation thereof, pharmaceutical products based on compounds, the use thereof, and intermediates
– Google Patents
AU612665B2 – 3-demethyl-4-fluoromevalonic acid derivatives, a process for the preparation thereof, pharmaceutical products based on compounds, the use thereof, and intermediates
– Google Patents
3-demethyl-4-fluoromevalonic acid derivatives, a process for the preparation thereof, pharmaceutical products based on compounds, the use thereof, and intermediates
Info
Publication number
AU612665B2
AU612665B2
AU18883/88A
AU1888388A
AU612665B2
AU 612665 B2
AU612665 B2
AU 612665B2
AU 18883/88 A
AU18883/88 A
AU 18883/88A
AU 1888388 A
AU1888388 A
AU 1888388A
AU 612665 B2
AU612665 B2
AU 612665B2
Authority
AU
Australia
Prior art keywords
compounds
preparation
acid derivatives
intermediates
demethyl
Prior art date
1987-07-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU18883/88A
Other versions
AU1888388A
(en
Inventor
Wilhelm Bartmann
Gerhard Beck
Andreas Bergmann
Hans-Hermann Lau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1987-07-10
Filing date
1988-07-08
Publication date
1991-07-18
1988-07-08
Application filed by Hoechst AG
filed
Critical
Hoechst AG
1989-01-12
Publication of AU1888388A
publication
Critical
patent/AU1888388A/en
1991-07-18
Application granted
granted
Critical
1991-07-18
Publication of AU612665B2
publication
Critical
patent/AU612665B2/en
2008-07-08
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
150000001875
compounds
Chemical class
0.000
title
abstract
3
238000002360
preparation method
Methods
0.000
title
abstract
3
239000002253
acid
Substances
0.000
title
abstract
2
239000000543
intermediate
Substances
0.000
title
abstract
2
238000000034
method
Methods
0.000
title
abstract
2
239000000825
pharmaceutical preparation
Substances
0.000
title
abstract
2
229940127557
pharmaceutical product
Drugs
0.000
title
1
MMCOUVMKNAHQOY-UHFFFAOYSA-N
carbonoperoxoic acid
Chemical class
OOC(O)=O
MMCOUVMKNAHQOY-UHFFFAOYSA-N
0.000
abstract
1
239000003814
drug
Substances
0.000
abstract
1
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/06—Antihyperlipidemics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C47/00—Compounds having —CHO groups
C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
C07C59/40—Unsaturated compounds
C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
C07C59/40—Unsaturated compounds
C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D309/10—Oxygen atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D309/30—Oxygen atoms, e.g. delta-lactones
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
C07F7/02—Silicon compounds
C07F7/08—Compounds having one or more C—Si linkages
C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
C07F7/1804—Compounds having Si-O-C linkages
Abstract
3-Desmethyl-4-fluoromevalonic acid derivatives of the formula I and the corresponding dihydroxycarboxylic acid derivatives of the formula II
in which R, X and Y have the meanings given, processes for the preparation of these compounds, their use as medicaments and pharmaceutical preparations are described. Novel intermediates for the preparation of the compounds of the formula I or formula II are additionally described.
AU18883/88A
1987-07-10
1988-07-08
3-demethyl-4-fluoromevalonic acid derivatives, a process for the preparation thereof, pharmaceutical products based on compounds, the use thereof, and intermediates
Ceased
AU612665B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19873722809
DE3722809A1
(en)
1987-07-10
1987-07-10
3-DESMETHYL-4-FLUOR-MEVALONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS, THEIR USE AND INTERMEDIATE PRODUCTS
DE3722809
1987-07-10
Publications (2)
Publication Number
Publication Date
AU1888388A
AU1888388A
(en)
1989-01-12
AU612665B2
true
AU612665B2
(en)
1991-07-18
Family
ID=6331294
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU18883/88A
Ceased
AU612665B2
(en)
1987-07-10
1988-07-08
3-demethyl-4-fluoromevalonic acid derivatives, a process for the preparation thereof, pharmaceutical products based on compounds, the use thereof, and intermediates
Country Status (19)
Country
Link
US
(1)
US4898868A
(en)
EP
(1)
EP0302253B1
(en)
JP
(1)
JPS6438086A
(en)
KR
(1)
KR890002084A
(en)
AT
(1)
ATE87916T1
(en)
AU
(1)
AU612665B2
(en)
CA
(1)
CA1319363C
(en)
DE
(2)
DE3722809A1
(en)
DK
(1)
DK383388A
(en)
ES
(1)
ES2054738T3
(en)
FI
(1)
FI883250A
(en)
HU
(1)
HU205071B
(en)
IE
(1)
IE62528B1
(en)
IL
(1)
IL87037A
(en)
NO
(1)
NO172537C
(en)
NZ
(1)
NZ225345A
(en)
PH
(1)
PH26770A
(en)
PT
(1)
PT87930B
(en)
ZA
(1)
ZA884922B
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU622342B2
(en)
*
1989-08-03
1992-04-02
Bayer Aktiengesellschaft
Imino-substituted pyridines
AU629977B2
(en)
*
1989-09-08
1992-10-15
Hoechst Aktiengesellschaft
4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, process for their preparation, their use as pharmaceuticals, and pharmaceutical preparations and precursors
Families Citing this family (11)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4681893A
(en)
*
1986-05-30
1987-07-21
Warner-Lambert Company
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
DE3826814A1
(en)
*
1988-08-06
1990-02-08
Hoechst Ag
NEW 6-FLUORO-3,5-DIHYDROXYCARBONSAEURES AND THEIR DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL PREPARATES AND INTERMEDIATE PRODUCTS
FI94339C
(en)
*
1989-07-21
1995-08-25
Warner Lambert Co
Process for the preparation of pharmaceutically acceptable [R- (R *, R *)] – 2- (4-fluorophenyl) -, – dihydroxy-5- (1-methylethyl) -3-phenyl-4 – [(phenylamino) carbonyl] -1H- for the preparation of pyrrole-1-heptanoic acid and its pharmaceutically acceptable salts
US5093363A
(en)
*
1989-08-22
1992-03-03
Shionogi & Co., Ltd.
2,4,6-substituted phenol derivatives
IT1237792B
(en)
*
1989-12-21
1993-06-17
Zambon Spa
ACTIVE COMPOUNDS AS INHIBITORS OF THE HMG-COA REDUCTASE ENZYME
DE69122284T2
(en)
*
1990-03-07
1997-02-06
Fujirebio Kk
4-hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid lowering agents
GB9013699D0
(en)
*
1990-06-20
1990-08-08
Rhone Poulenc Sante
New process
CN102086184A
(en)
*
2011-03-03
2011-06-08
上海应用技术学院
5-fluorine-substituted 4-hydroxyl-3,4,5,6-tetrahydro-2H-pyrane-2-ketone compound and preparation method thereof
CN102153463A
(en)
*
2011-03-03
2011-08-17
上海应用技术学院
4-subsititued 3,5-dihydroxy carboxylic acid compound and preparation method thereof
CN104262248A
(en)
*
2014-09-03
2015-01-07
上海应用技术学院
Method for preparing 5-substituted 4,4-difluoro-3,5-dihydrocarboxylic acid and metal salts thereof
CN104351190A
(en)
*
2014-10-23
2015-02-18
上海应用技术学院
Application of 4 gem-Gem-difluoromethylene substituted 3, 5 dyhydroxyl polycarboxylic compound to pest control
Citations (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU1888288A
(en)
*
1987-07-10
1989-01-12
Hoechst Aktiengesellschaft
3-demthylmevalonic acid derivatives, a process for their preparation pharmaceutical products based on these compounds, their use and intermediates
AU3929789A
(en)
*
1988-08-06
1990-02-08
Hoechst Aktiengesellschaft
New 6-fluoro-3,5-dihydroxy carboxylic acids and derivatives thereof, a process for the preparation thereof, the use thereof as medicinal agents, pharmaceutical products and intermediates
AU4161589A
(en)
*
1988-09-24
1990-03-29
Hoechst Aktiengesellschaft
7-substituted derivatives of 3,5-dihydroxyhept-6-ynoic acid, a process for the preparation thereof, the use thereof as pharmaceuticals, and intermediates
Family Cites Families (10)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS53147073A
(en)
*
1977-05-24
1978-12-21
Sankyo Co Ltd
Mevalonolactone derivatives
US4562258A
(en)
*
1982-02-04
1985-12-31
Findlay John W A
6-[3-Amino-1-(4-tolyl)prop-1E-enyl]pyridine-2-carboxylic acid derivatives having antihistaminic activity
US4647576A
(en)
*
1984-09-24
1987-03-03
Warner-Lambert Company
Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
DE3530798A1
(en)
*
1985-08-29
1987-03-05
Hoechst Ag
6-Phenoxymethyl-4-hydroxytetrahydropyran-2-ones, processes for their preparation, their use as medicaments, pharmaceutical preparations and intermediates
EP0216127B1
(en)
*
1985-08-29
1990-09-26
Hoechst Aktiengesellschaft
6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones, process for their preparation, their use as medicines, pharmaceutical compositions and intermediates
DE3530797A1
(en)
*
1985-08-29
1987-03-05
Hoechst Ag
3-Desmethylmevalonic acid derivatives, processes for their preparation, pharmaceutical preparations based on these compounds, their use and their intermediates
DE3669874D1
(en)
*
1985-08-29
1990-05-03
Hoechst Ag
3-DESMETHYL MEVALONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS, THEIR USE AND INTERMEDIATE PRODUCTS.
US4812460A
(en)
*
1986-03-25
1989-03-14
Boehringer Ingelheim Pharmaceutical, Inc.
3-[2-(3′,5′-di-t-butyl-4′-hydroxyphenyl)ethenyl]pyridine
DE3632893A1
(en)
*
1986-09-27
1988-04-07
Hoechst Ag
4-(R)-Hydroxy-6-(S)-arylthiomethyltetrahydropyran-2-ones, their corresponding sulphoxides and sulphones, processes for their preparation, their use as medicaments, pharmaceutical preparations and intermediates
US6622253B2
(en)
*
2001-08-02
2003-09-16
Scientific-Atlanta, Inc.
Controlling processor clock rate based on thread priority
1987
1987-07-10
DE
DE19873722809
patent/DE3722809A1/en
not_active
Withdrawn
1988
1988-07-07
FI
FI883250A
patent/FI883250A/en
not_active
Application Discontinuation
1988-07-07
ES
ES88110834T
patent/ES2054738T3/en
not_active
Expired – Lifetime
1988-07-07
AT
AT88110834T
patent/ATE87916T1/en
not_active
IP Right Cessation
1988-07-07
PT
PT87930A
patent/PT87930B/en
not_active
IP Right Cessation
1988-07-07
DE
DE8888110834T
patent/DE3880041D1/en
not_active
Expired – Fee Related
1988-07-07
EP
EP88110834A
patent/EP0302253B1/en
not_active
Expired – Lifetime
1988-07-08
NZ
NZ225345A
patent/NZ225345A/en
unknown
1988-07-08
DK
DK383388A
patent/DK383388A/en
not_active
Application Discontinuation
1988-07-08
US
US07/216,752
patent/US4898868A/en
not_active
Expired – Fee Related
1988-07-08
AU
AU18883/88A
patent/AU612665B2/en
not_active
Ceased
1988-07-08
JP
JP63169164A
patent/JPS6438086A/en
active
Pending
1988-07-08
ZA
ZA884922A
patent/ZA884922B/en
unknown
1988-07-08
HU
HU883595A
patent/HU205071B/en
not_active
IP Right Cessation
1988-07-08
IL
IL8703788A
patent/IL87037A/en
not_active
IP Right Cessation
1988-07-08
PH
PH37203A
patent/PH26770A/en
unknown
1988-07-08
NO
NO883074A
patent/NO172537C/en
unknown
1988-07-08
IE
IE210088A
patent/IE62528B1/en
not_active
IP Right Cessation
1988-07-08
CA
CA000571559A
patent/CA1319363C/en
not_active
Expired – Fee Related
1988-07-09
KR
KR1019880008549A
patent/KR890002084A/en
not_active
Application Discontinuation
Patent Citations (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU1888288A
(en)
*
1987-07-10
1989-01-12
Hoechst Aktiengesellschaft
3-demthylmevalonic acid derivatives, a process for their preparation pharmaceutical products based on these compounds, their use and intermediates
AU3929789A
(en)
*
1988-08-06
1990-02-08
Hoechst Aktiengesellschaft
New 6-fluoro-3,5-dihydroxy carboxylic acids and derivatives thereof, a process for the preparation thereof, the use thereof as medicinal agents, pharmaceutical products and intermediates
AU4161589A
(en)
*
1988-09-24
1990-03-29
Hoechst Aktiengesellschaft
7-substituted derivatives of 3,5-dihydroxyhept-6-ynoic acid, a process for the preparation thereof, the use thereof as pharmaceuticals, and intermediates
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU622342B2
(en)
*
1989-08-03
1992-04-02
Bayer Aktiengesellschaft
Imino-substituted pyridines
AU629977B2
(en)
*
1989-09-08
1992-10-15
Hoechst Aktiengesellschaft
4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, process for their preparation, their use as pharmaceuticals, and pharmaceutical preparations and precursors
Also Published As
Publication number
Publication date
PT87930B
(en)
1995-03-01
NZ225345A
(en)
1991-05-28
DE3880041D1
(en)
1993-05-13
IE62528B1
(en)
1995-02-08
DK383388A
(en)
1989-01-11
CA1319363C
(en)
1993-06-22
NO172537C
(en)
1993-08-04
KR890002084A
(en)
1989-04-08
AU1888388A
(en)
1989-01-12
PH26770A
(en)
1992-09-28
JPS6438086A
(en)
1989-02-08
NO883074D0
(en)
1988-07-08
DK383388D0
(en)
1988-07-08
HU205071B
(en)
1992-03-30
NO172537B
(en)
1993-04-26
NO883074L
(en)
1989-01-11
HUT51221A
(en)
1990-04-28
US4898868A
(en)
1990-02-06
ZA884922B
(en)
1989-01-17
IL87037A0
(en)
1988-12-30
EP0302253A1
(en)
1989-02-08
PT87930A
(en)
1989-06-30
IL87037A
(en)
1995-03-30
FI883250A0
(en)
1988-07-07
ES2054738T3
(en)
1994-08-16
ATE87916T1
(en)
1993-04-15
DE3722809A1
(en)
1989-01-19
IE882100L
(en)
1989-01-10
EP0302253B1
(en)
1993-04-07
FI883250A
(en)
1989-01-11
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None