GB1087729A – Novel pharmacologically active steroid compounds of the pregnane series, processes for their preparation, and pharmaceutical compositions containing them
– Google Patents
GB1087729A – Novel pharmacologically active steroid compounds of the pregnane series, processes for their preparation, and pharmaceutical compositions containing them
– Google Patents
Novel pharmacologically active steroid compounds of the pregnane series, processes for their preparation, and pharmaceutical compositions containing them
Info
Publication number
GB1087729A
GB1087729A
GB51833/64A
GB5183364A
GB1087729A
GB 1087729 A
GB1087729 A
GB 1087729A
GB 51833/64 A
GB51833/64 A
GB 51833/64A
GB 5183364 A
GB5183364 A
GB 5183364A
GB 1087729 A
GB1087729 A
GB 1087729A
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical compositions
compositions containing
processes
preparation
pharmacologically active
Prior art date
1964-01-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB51833/64A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1964-01-02
Filing date
1964-12-21
Publication date
1967-10-18
1964-12-21
Application filed by Roussel Uclaf SA
filed
Critical
Roussel Uclaf SA
1967-10-18
Publication of GB1087729A
publication
Critical
patent/GB1087729A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J75/00—Processes for the preparation of steroids in general
Abstract
Novel 21 – (apocamphane – 1 – carbonyloxy)-20 – oxo – steroids of the pregnane series are obtained in a process in which a functional derivative of apocamphane-1-carboxylic acid is reacted with a 21-hydroxy-20-oxo steroid of the partial general formula St-CO-CH2OH (wherein St represents a steroid nucleus), in the presence of a tertiary base, e.g. pyridine, N,N-dimethylaniline or triethylamine, to give the corresponding 21 – (apocamphane – 1 – carbonyloxy)-20-oxo-steroid Pharmaceutical compositions containing the above compounds and having anti-inflammatory activity are administered parenterally, topically or rectally.
GB51833/64A
1964-01-02
1964-12-21
Novel pharmacologically active steroid compounds of the pregnane series, processes for their preparation, and pharmaceutical compositions containing them
Expired
GB1087729A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
FR959163A
FR3316M
(en)
1964-01-02
1964-01-02
New drug in particular for the treatment of inflammatory manifestations of rheumatic, arthritic or infectious origin.
FR966962A
FR1512324A
(en)
1964-01-02
1964-03-11
New esters in 21 of cortisone derivatives and method of preparation
Publications (1)
Publication Number
Publication Date
GB1087729A
true
GB1087729A
(en)
1967-10-18
Family
ID=26205184
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB51833/64A
Expired
GB1087729A
(en)
1964-01-02
1964-12-21
Novel pharmacologically active steroid compounds of the pregnane series, processes for their preparation, and pharmaceutical compositions containing them
Country Status (10)
Country
Link
BE
(1)
BE657319A
(en)
BR
(1)
BR6465428D0
(en)
CH
(1)
CH436282A
(en)
DE
(1)
DE1468892B1
(en)
DK
(1)
DK112236B
(en)
FR
(2)
FR3316M
(en)
GB
(1)
GB1087729A
(en)
IL
(1)
IL22709A
(en)
NL
(2)
NL6414704A
(en)
SE
(1)
SE318274B
(en)
Families Citing this family (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB1439605A
(en)
*
1972-07-14
1976-06-16
Akzo Nv
2beta-hydroxy-3-alpha-amino-steroids and derivatives thereof and the processes for their preparation
0
BE
BE657319D
patent/BE657319A/xx
unknown
NL
NL122978D
patent/NL122978C/xx
active
1964
1964-01-02
FR
FR959163A
patent/FR3316M/en
active
Active
1964-03-11
FR
FR966962A
patent/FR1512324A/en
not_active
Expired
1964-12-15
DE
DE19641468892
patent/DE1468892B1/en
not_active
Withdrawn
1964-12-17
NL
NL6414704A
patent/NL6414704A/xx
unknown
1964-12-17
BR
BR16542864A
patent/BR6465428D0/en
unknown
1964-12-18
DK
DK622064A
patent/DK112236B/en
unknown
1964-12-18
SE
SE1542164A
patent/SE318274B/xx
unknown
1964-12-18
CH
CH1636164A
patent/CH436282A/en
unknown
1964-12-21
GB
GB51833/64A
patent/GB1087729A/en
not_active
Expired
1964-12-31
IL
IL2270964A
patent/IL22709A/en
unknown
Also Published As
Publication number
Publication date
IL22709A
(en)
1969-02-27
FR3316M
(en)
1965-05-17
CH436282A
(en)
1967-05-31
SE318274B
(en)
1969-12-08
NL122978C
(en)
FR1512324A
(en)
1968-02-09
DE1468892B1
(en)
1970-03-12
NL6414704A
(en)
1965-07-05
BE657319A
(en)
BR6465428D0
(en)
1973-08-07
DK112236B
(en)
1968-11-25
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