GB1249490A – New sulphamyl-benzoic acid derivatives
– Google Patents
GB1249490A – New sulphamyl-benzoic acid derivatives
– Google Patents
New sulphamyl-benzoic acid derivatives
Info
Publication number
GB1249490A
GB1249490A
GB38038/69A
GB6133968A
GB1249490A
GB 1249490 A
GB1249490 A
GB 1249490A
GB 38038/69 A
GB38038/69 A
GB 38038/69A
GB 6133968 A
GB6133968 A
GB 6133968A
GB 1249490 A
GB1249490 A
GB 1249490A
Authority
GB
United Kingdom
Prior art keywords
radicals
signify
preparations
benzoic acid
dec
Prior art date
1968-12-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB38038/69A
Inventor
Peter Werner Feit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1968-12-24
Filing date
1968-12-24
Publication date
1971-10-13
1968-12-24
Application filed by Leo Pharmaceutical Products Ltd AS
filed
Critical
Leo Pharmaceutical Products Ltd AS
1968-12-24
Priority to GB38038/69A
priority
Critical
patent/GB1249490A/en
1969-12-08
Priority to IE1644/69A
priority
patent/IE33874B1/en
1969-12-12
Priority to IL33526A
priority
patent/IL33526A/en
1969-12-15
Priority to IS1894A
priority
patent/IS985B6/en
1969-12-16
Priority to BR21520069A
priority
patent/BR6915200D0/en
1969-12-17
Priority to FI693661A
priority
patent/FI51587C/en
1969-12-18
Priority to ES374688A
priority
patent/ES374688A1/en
1969-12-22
Priority to CH1916169A
priority
patent/CH532559A/en
1969-12-22
Priority to AT1192669A
priority
patent/AT308069B/en
1969-12-22
Priority to DK677369AA
priority
patent/DK134548B/en
1969-12-22
Priority to US00887409A
priority
patent/US3806534A/en
1969-12-22
Priority to YU3190/69A
priority
patent/YU34983B/en
1969-12-22
Priority to PL17333969A
priority
patent/PL84447B1/pl
1969-12-23
Priority to FR6944650A
priority
patent/FR2027043B1/fr
1969-12-23
Priority to IT54483/69A
priority
patent/IT1143801B/en
1969-12-23
Priority to LU60092D
priority
patent/LU60092A1/xx
1969-12-23
Priority to NO5119/69A
priority
patent/NO132234C/no
1969-12-23
Priority to SE6917917A
priority
patent/SE380013B/xx
1969-12-23
Priority to DE19691966878
priority
patent/DE1966878C3/en
1969-12-23
Priority to DE1964504A
priority
patent/DE1964504C3/en
1969-12-23
Priority to DE19691964503
priority
patent/DE1964503A1/en
1969-12-24
Priority to JP10372669A
priority
patent/JPS5420483B1/ja
1969-12-24
Priority to NL696919391A
priority
patent/NL154727B/en
1969-12-24
Priority to RO6195569A
priority
patent/RO62015A/en
1969-12-24
Priority to BG13606A
priority
patent/BG17812A3/xx
1969-12-24
Priority to BE743744D
priority
patent/BE743744A/xx
1969-12-24
Priority to SU1389768A
priority
patent/SU512700A3/en
1971-10-13
Publication of GB1249490A
publication
Critical
patent/GB1249490A/en
1973-08-14
Priority to CY69773A
priority
patent/CY697A/en
1973-11-15
Priority to US05/416,163
priority
patent/US3971819A/en
1973-11-15
Priority to US05/416,164
priority
patent/US3985777A/en
1973-12-26
Priority to JP48144149A
priority
patent/JPS5024299B1/ja
1974-12-31
Priority to MY7400239A
priority
patent/MY7400239A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
A61K31/19—Carboxylic acids, e.g. valproic acid
A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D213/72—Nitrogen atoms
C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
Abstract
1,249,490. Antihypertensive &c. medicines. LOVENS KEMISKE FABRIK PRODUKTION SAKTIESEL SKAB. 22 Dec., 1969 [24 Dec., 1968; 18 June, 1969; 29 July, 1969], Nos. 61339/68, 30898/68 and 38038/69. Heading A5B. [Also in Division C2] Pharmaceutical preparations, especially suitable for treating hypertension and oedematous conditions, contain I (including salts, esters, amides and hydrates thereof) as active ingredient where A signifies NR 1 R 2 , OR 2 , SR 2 , SOR 2 or SO 2 R 2 , R 1 to R 4 are optionally substituted, saturated or unsaturated radicals and accordingly signify aliphatic or cycloaliphatic radicals or aromatically, cycloaliphatically or heterocyclically substituted aliphatic radicals, R 2 and R 3 can also be aromatic and heterocyclic radicals and NR 1 R 2 can also signify a heterocyclic ring system with 5 to 8 ring members, R 5 is alkyl, R 6 is alkyl or acyl and R 1 , R 3 , R 4 , R 5 and R 6 may also signify H; e.g. 3-butylamino- 4-phenoxy-5-sulphamoyl-benzoic acid and its derivatives. Other actives may also be incorporated in the preparations, e.g. other hypotensives, and/or tranquilizers, and/or potassiumsparing diuretics and/or saluretics, such as Rauwolfia and veratrum alkaloids, hydralazine, methyldopa, triamterene, 3,5-diamino-6- chloropyrazinoylguanidine, meprobamate, hydroflumethiazide and bendroflumethiazide; carboanhydrase inhibitors and aldosterone antagonists, e.g. spironolactone, may also be utilized in the preparations. Administration is, e.g. enterally or orally.
GB38038/69A
1968-12-24
1968-12-24
New sulphamyl-benzoic acid derivatives
Expired
GB1249490A
(en)
Priority Applications (32)
Application Number
Priority Date
Filing Date
Title
GB38038/69A
GB1249490A
(en)
1968-12-24
1968-12-24
New sulphamyl-benzoic acid derivatives
IE1644/69A
IE33874B1
(en)
1968-12-24
1969-12-08
New sulphamyl-benzoic acid derivatives
IL33526A
IL33526A
(en)
1968-12-24
1969-12-12
Sulphamyl-benzoic acid derivatives,their preparation and pharmaceutical compositions containing them
IS1894A
IS985B6
(en)
1968-12-24
1969-12-15
Process for the production of new sulphamyl-benzoic acid by-products
BR21520069A
BR6915200D0
(en)
1968-12-24
1969-12-16
CHEMICAL PROCESS
FI693661A
FI51587C
(en)
1968-12-24
1969-12-17
Process for the preparation of sulfamyl-m-aminobenzoic acids with therapeutic action.
ES374688A
ES374688A1
(en)
1968-12-24
1969-12-18
Sulphamyl-benzoic acid derivatives
CH1916169A
CH532559A
(en)
1968-12-24
1969-12-22
Process for the preparation of sulfamylbenzoic acid derivatives and their use
AT1192669A
AT308069B
(en)
1968-12-24
1969-12-22
Process for the preparation of new 3-amino-5-sulfamylbenzoic acids
DK677369AA
DK134548B
(en)
1968-12-24
1969-12-22
Analogous process for the preparation of sulfamyl-m-aminobenzoic acids or salts, esters or amides thereof.
US00887409A
US3806534A
(en)
1968-12-24
1969-12-22
Sulphamyl-benzoic acid derivatives
YU3190/69A
YU34983B
(en)
1968-12-24
1969-12-22
Process for preparing sulfamylbenzoic acid derivatives
PL17333969A
PL84447B1
(en)
1968-12-24
1969-12-22
LU60092D
LU60092A1
(en)
1968-12-24
1969-12-23
IT54483/69A
IT1143801B
(en)
1968-12-24
1969-12-23
PROCEDURE FOR THE PREPARATION OF ACID DERIVATIVES ON SULFAMYL BENZOIC
FR6944650A
FR2027043B1
(en)
1968-12-24
1969-12-23
NO5119/69A
NO132234C
(en)
1968-12-24
1969-12-23
SE6917917A
SE380013B
(en)
1968-12-24
1969-12-23
DE19691966878
DE1966878C3
(en)
1968-12-24
1969-12-23
S-Butylamine M-phenoxy-S-sulfamylbenzoic acid and its derivatives, processes for their preparation and compositions containing them
DE1964504A
DE1964504C3
(en)
1968-12-24
1969-12-23
Medicines for the treatment of edematous conditions and hypertension
DE19691964503
DE1964503A1
(en)
1968-12-24
1969-12-23
New sulfamylbenzoic acid derivatives
BG13606A
BG17812A3
(en)
1968-12-24
1969-12-24
NL696919391A
NL154727B
(en)
1968-12-24
1969-12-24
PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH DIURETIC ACTION AND THE PREPARED MEDICINAL PRODUCT THEREFORE OBTAINED, AND A PROCESS OF PREPARING AN AMMONA SUSTAINABLE FOR INCLUSION IN SUCH MEDICINAL 5-SONAMOUS-3-SONAMOUS-3-SOSOLA.
RO6195569A
RO62015A
(en)
1968-12-24
1969-12-24
PROCESS FOR OBTAINING SULFAMYLEBENZOIC ACID DERIVATIVES
JP10372669A
JPS5420483B1
(en)
1968-12-24
1969-12-24
BE743744D
BE743744A
(en)
1968-12-24
1969-12-24
SU1389768A
SU512700A3
(en)
1968-12-24
1969-12-24
The method of obtaining sulfamylbenzoic acid derivatives
CY69773A
CY697A
(en)
1968-12-24
1973-08-14
New sulphamyl-benzoic acid derivatives
US05/416,163
US3971819A
(en)
1968-12-24
1973-11-15
3-Amino, 4-thio-substituted, 5-sulphamyl-benzoic acid derivatives
US05/416,164
US3985777A
(en)
1968-12-24
1973-11-15
Sulphamyl-benzoic acid derivatives
JP48144149A
JPS5024299B1
(en)
1968-12-24
1973-12-26
MY7400239A
MY7400239A
(en)
1968-12-24
1974-12-31
New sulphamyl-benzoic acid derivatives
Applications Claiming Priority (3)
Application Number
Priority Date
Filing Date
Title
GB38038/69A
GB1249490A
(en)
1968-12-24
1968-12-24
New sulphamyl-benzoic acid derivatives
GB3089869
1969-06-18
GB3803869
1969-07-29
Publications (1)
Publication Number
Publication Date
GB1249490A
true
GB1249490A
(en)
1971-10-13
Family
ID=27258934
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB38038/69A
Expired
GB1249490A
(en)
1968-12-24
1968-12-24
New sulphamyl-benzoic acid derivatives
Country Status (7)
Country
Link
US
(1)
US3806534A
(en)
BG
(1)
BG17812A3
(en)
CY
(1)
CY697A
(en)
ES
(1)
ES374688A1
(en)
GB
(1)
GB1249490A
(en)
IL
(1)
IL33526A
(en)
LU
(1)
LU60092A1
(en)
Families Citing this family (19)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB1406882A
(en)
*
1972-04-28
1975-09-17
Leo Pharm Prod Ltd
Benzoic acid derivatives and benzisptjoaup’e 1.1 dopxode derovatoves
GB1399632A
(en)
*
1972-07-13
1975-07-02
Leo Pharm Prod Ltd
Sulphamoyl-benzoic acids
AR206507A1
(en)
*
1972-10-13
1976-07-30
Ciba Geigy Ag
PROCEDURE FOR THE OBTAINING OF NEW 4-ETHERS OF 3-AMINO-5-SULFAMOYLBENZOIC ACIDS
US3939267A
(en)
*
1972-10-13
1976-02-17
Ciba-Geigy Corporation
4-Ethers of 3-amino-5-sulfamoylbenzoic acids
US3982018A
(en)
*
1973-08-08
1976-09-21
Ciba-Geigy Corporation
4-Ethers of 3-amino-5-sulfamoylbenzoic acids
NL7411618A
(en)
*
1973-09-07
1975-03-11
Hoechst Ag
PROCESS FOR PREPARING SUBSTITUTED AMINOBENZOIC ACID DERIVATIVES.
GB1523631A
(en)
*
1975-07-08
1978-09-06
Leo Pharm Prod Ltd
Sulphonamide derivatives
DE2966048D1
(en)
*
1978-07-20
1983-09-15
Basf Ag
N-arylsulfonyl pyrroles, their preparation and medicaments containing them
DE2849646A1
(en)
*
1978-11-16
1980-06-04
Hoechst Ag
THIENYLBENZOESAE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
DE3208189A1
(en)
*
1982-03-06
1983-09-08
Hoechst Ag, 6230 Frankfurt
2-AMINOMETHYL-6-SULFAMOYLPHENOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
CA1294974C
(en)
*
1987-05-08
1992-01-28
Sanji Hagishita
Bicyclic sulfonamide derivatives and process therefor
IT1288123B1
(en)
*
1996-09-04
1998-09-10
Nicox Sa
USE OF NITRO-DERIVATIVES FOR URINARY INCONTINENCE
US8008283B2
(en)
*
1998-12-23
2011-08-30
Neurotherapeutics Pharma, Inc.
Methods and compositions for the treatment of neuropsychiatric disorders
US7214711B2
(en)
*
1998-12-23
2007-05-08
Neurotherapeutics Pharma Llc
Method of treating migraine headache without aura
US8722668B2
(en)
*
1998-12-23
2014-05-13
Daryl W. Hochman
Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
EA200500234A1
(en)
2002-08-19
2005-08-25
Пфайзер Продактс Инк.
COMBINED THERAPY OF HYPERPROLIFERATIVE DISEASES
US20080275093A1
(en)
*
2004-11-15
2008-11-06
Nitromed, Inc.
Diuretic Compounds Comprising Heterocyclic Nitric Oxide Donor Groups, Compositions and Methods of Use
JP2009511629A
(en)
*
2005-10-17
2009-03-19
ニューロセラピューティクス ファーマ， インコーポレイテッド
Analogues of diuretic-like compounds useful in the regulation of central nervous system diseases
EP2887806B1
(en)
2012-07-20
2019-11-13
University Of Rochester
Method of treating and preventing brain impairment using na+-k+ -2ci- cotransporter isoform 1 inhibitors
1968
1968-12-24
GB
GB38038/69A
patent/GB1249490A/en
not_active
Expired
1969
1969-12-12
IL
IL33526A
patent/IL33526A/en
unknown
1969-12-18
ES
ES374688A
patent/ES374688A1/en
not_active
Expired
1969-12-22
US
US00887409A
patent/US3806534A/en
not_active
Expired – Lifetime
1969-12-23
LU
LU60092D
patent/LU60092A1/xx
unknown
1969-12-24
BG
BG13606A
patent/BG17812A3/xx
unknown
1973
1973-08-14
CY
CY69773A
patent/CY697A/en
unknown
Also Published As
Publication number
Publication date
BG17812A3
(en)
1973-12-25
LU60092A1
(en)
1970-02-23
IL33526A0
(en)
1970-02-19
CY697A
(en)
1973-08-14
ES374688A1
(en)
1971-04-01
IL33526A
(en)
1973-11-28
US3806534A
(en)
1974-04-23
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Legal Events
Date
Code
Title
Description
1972-02-23
PS
Patent sealed [section 19, patents act 1949]
1986-12-31
746B
Proceeding under section 46(3) patents act 1977
1987-07-08
746B
Proceeding under section 46(3) patents act 1977
1987-12-02
746B
Proceeding under section 46(3) patents act 1977
1987-12-23
746B
Proceeding under section 46(3) patents act 1977
1988-07-20
746B
Proceeding under section 46(3) patents act 1977
1990-01-24
PE20
Patent expired after termination of 20 years
