GB1313539A – Sulphonyl-ureas
– Google Patents
GB1313539A – Sulphonyl-ureas
– Google Patents
Sulphonyl-ureas
Info
Publication number
GB1313539A
GB1313539A
GB3172270A
GB3172270A
GB1313539A
GB 1313539 A
GB1313539 A
GB 1313539A
GB 3172270 A
GB3172270 A
GB 3172270A
GB 3172270 A
GB3172270 A
GB 3172270A
GB 1313539 A
GB1313539 A
GB 1313539A
Authority
GB
United Kingdom
Prior art keywords
optionally substituted
compounds
june
alkyl
sulphonyl
Prior art date
1969-07-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3172270A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1969-07-01
Filing date
1970-06-30
Publication date
1973-04-11
1969-07-01
Priority claimed from DE19691933388
external-priority
patent/DE1933388A1/en
1970-06-04
Priority claimed from DE19702027436
external-priority
patent/DE2027436A1/en
1970-06-30
Application filed by Dr Karl Thomae GmbH
filed
Critical
Dr Karl Thomae GmbH
1973-04-11
Publication of GB1313539A
publication
Critical
patent/GB1313539A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
C07D223/16—Benzazepines; Hydrogenated benzazepines
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
Abstract
1313539 Sulphonyl-ureas DR KARL THOMAE GmbH 30 June 1970 [1 July 1969 4 June 1970] 31722/70 Heading C2C Novel compounds I (including salts thereof) where R 1 is C 1-4 alkyl, phenyl optionally substituted by C 1-3 alkoxy, Me or CF 3 , by one or two halogens or by 2-MeO and 5-Cl, or is biphenyl, α – naphthyl, 1,2,3,4 – tetrahydronaphthyl-(1), indanyl-(1) or benzoyl, R 2 is nbutyl, C 5-8 cycloalkyl optionally substituted by Me or Et, or is adamantyl-(1), A is a C 1-5 bivalent aliphatic hydrocarbon group optionally substituted by Ph or is a direct bond and n is 1 or 2, are made by standard methods utilizing compounds II and compounds VI (X signifies NH 2 or NHCO 2 alkyl; salts of II are also exemplified); N,N-bis-carbethoxy-2- (3 – phenylpropionyl) – 1,2,3,4 – tetrahydroisoquinoline-7-sulphonamide is also described. Pharmaceutical preparations showing, in particular, hypoglycaemic activity contain (I) as active ingredient; administration may be orally, rectally or parenterally.
GB3172270A
1969-07-01
1970-06-30
Sulphonyl-ureas
Expired
GB1313539A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19691933388
DE1933388A1
(en)
1969-07-01
1969-07-01
New sulfonylureas and processes for their preparation
DE19702027436
DE2027436A1
(en)
1970-06-04
1970-06-04
Sulphenylurea cpds, hypoglycaemics
Publications (1)
Publication Number
Publication Date
GB1313539A
true
GB1313539A
(en)
1973-04-11
Family
ID=25757577
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB3172270A
Expired
GB1313539A
(en)
1969-07-01
1970-06-30
Sulphonyl-ureas
Country Status (16)
Country
Link
AT
(1)
AT301568B
(en)
BE
(1)
BE752760A
(en)
BG
(1)
BG18181A1
(en)
CH
(1)
CH536842A
(en)
DK
(1)
DK127928B
(en)
ES
(2)
ES381248A1
(en)
FI
(1)
FI49828C
(en)
FR
(1)
FR2059465B1
(en)
GB
(1)
GB1313539A
(en)
IE
(1)
IE34359B1
(en)
IL
(1)
IL34820A
(en)
NL
(1)
NL7009704A
(en)
NO
(1)
NO132094C
(en)
PL
(1)
PL81112B1
(en)
RO
(1)
RO56857A
(en)
SE
(1)
SE357745B
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
WO2001087834A1
(en)
*
2000-05-16
2001-11-22
Takeda Chemical Industries, Ltd.
Melanin-concentrating hormone antagonist
1970
1970-06-17
FI
FI701712A
patent/FI49828C/en
active
1970-06-24
SE
SE08771/70A
patent/SE357745B/xx
unknown
1970-06-25
RO
RO63739A
patent/RO56857A/ro
unknown
1970-06-26
BG
BG16831A
patent/BG18181A1/xx
unknown
1970-06-27
ES
ES381248A
patent/ES381248A1/en
not_active
Expired
1970-06-29
CH
CH982470A
patent/CH536842A/en
not_active
IP Right Cessation
1970-06-30
PL
PL1970141708A
patent/PL81112B1/en
unknown
1970-06-30
IE
IE856/70A
patent/IE34359B1/en
unknown
1970-06-30
IL
IL34820A
patent/IL34820A/en
unknown
1970-06-30
DK
DK338970AA
patent/DK127928B/en
unknown
1970-06-30
NO
NO2575/70A
patent/NO132094C/no
unknown
1970-06-30
GB
GB3172270A
patent/GB1313539A/en
not_active
Expired
1970-06-30
AT
AT586870A
patent/AT301568B/en
not_active
IP Right Cessation
1970-06-30
BE
BE752760D
patent/BE752760A/en
unknown
1970-07-01
FR
FR7024368A
patent/FR2059465B1/fr
not_active
Expired
1970-07-01
NL
NL7009704A
patent/NL7009704A/xx
unknown
1971
1971-07-19
ES
ES393416A
patent/ES393416A1/en
not_active
Expired
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
WO2001087834A1
(en)
*
2000-05-16
2001-11-22
Takeda Chemical Industries, Ltd.
Melanin-concentrating hormone antagonist
US7229986B2
(en)
2000-05-16
2007-06-12
Takeda Pharmaceutical Company Ltd.
Melanin-concentrating hormone antagonist
Also Published As
Publication number
Publication date
AT301568B
(en)
1972-09-11
SE357745B
(en)
1973-07-09
NO132094B
(en)
1975-06-09
NL7009704A
(en)
1971-01-05
RO56857A
(en)
1974-12-15
IE34359B1
(en)
1975-04-16
FI49828B
(en)
1975-06-30
BG18181A1
(en)
1974-09-02
DK127928B
(en)
1974-02-04
ES393416A1
(en)
1974-06-01
CH536842A
(en)
1973-05-15
ES381248A1
(en)
1972-11-01
FI49828C
(en)
1975-10-10
NO132094C
(en)
1975-09-17
FR2059465B1
(en)
1974-03-22
FR2059465A1
(en)
1971-06-04
BE752760A
(en)
1970-12-30
IL34820A
(en)
1973-08-29
PL81112B1
(en)
1975-08-30
IE34359L
(en)
1971-01-01
IL34820A0
(en)
1970-09-17
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Legal Events
Date
Code
Title
Description
1973-08-22
PS
Patent sealed [section 19, patents act 1949]
1977-01-26
PLNP
Patent lapsed through nonpayment of renewal fees