GB1318562A - Creación de Inventos y Patentes con Inteligencia Artificial

GB1318562A – Manufacture of derivatives of 7-aminocephalosporanic acid
– Google Patents

GB1318562A – Manufacture of derivatives of 7-aminocephalosporanic acid
– Google Patents
Manufacture of derivatives of 7-aminocephalosporanic acid

Info

Publication number
GB1318562A

GB1318562A
GB2677970A
GB2677970A
GB1318562A
GB 1318562 A
GB1318562 A
GB 1318562A
GB 2677970 A
GB2677970 A
GB 2677970A
GB 2677970 A
GB2677970 A
GB 2677970A
GB 1318562 A
GB1318562 A
GB 1318562A
Authority
GB
United Kingdom
Prior art keywords
group
compound
replaced
formula
ester
Prior art date
1969-06-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB2677970A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1969-06-06
Filing date
1970-06-03
Publication date
1973-05-31

1970-06-03
Application filed by Ciba Geigy AG
filed
Critical
Ciba Geigy AG

1973-05-31
Publication of GB1318562A
publication
Critical
patent/GB1318562A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

C07D501/14—Compounds having a nitrogen atom directly attached in position 7

C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE

Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS

Y02P20/00—Technologies relating to chemical industry

Y02P20/50—Improvements relating to the production of bulk chemicals

Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

1318562 7 – Azidoacetylaminocephalosporanic acid derivatives CIBA-GEIBY AG 3 June 1970 [6 June 1969] 26779/70 Heading C2A The invention comprises 7 – azidoacetylaminocephalosporanic acid derivatives of Formula I in which R is H, hydroxyl esterified by a carboxylic acid in which ester O may be replaced by S (except the acetoxy group), an unsubstituted or N-substituted carbamoyloxy group in which oxygen may be replaced by sulphur, or a quaternary amino group, or a salt thereof. The compounds are prepared by (a) reacting a compound of Formula II in which Z is a reactive esterified hydroxyacetyl residue and R1 is H, OH or esterified OH (in which the ester oxygen may be replaced by a sulphur atom), with a metal azide, (b) acylating a compound of Formula II in which Z is H and R1 is H, OH or an esterified OH (in which ester O may be replaced by S) with the group N 3 -CH 2 -CO- and (c) a resulting compound obtained according to (a) or (b), and in which R1 represents the acetoxy group is converted to a compound in which R1 is a free hydroxyl group or into a compound of Formula I in which R is a quaternary amino group, or a compound in which R1 is a free OH group is converted into a compound of Formula I containing an ester group other than acetory (in which oxygen atoms may be replaced by sulphur atoms) or an unsubstituted or N-substituted carbamyloxy group in which O may be replaced by S atoms. The carboxyl group of process (a) or (b) may be protected by an eliminable protective group and, in a final step, this group is split off in known manner to produce the compounds of Formula I. Salts are formed with alkali metals, alkaline earth metals, ammonia or organic bases such as procaine. The 7 – azidoacetylaminocephalosporanic acid or salts thereof may be incorporated in veterinary or pharmaceutical preparations and animal feed stuffs.

GB2677970A
1969-06-06
1970-06-03
Manufacture of derivatives of 7-aminocephalosporanic acid

Expired

GB1318562A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

CH865669A

CH524633A
(en)

1969-06-06
1969-06-06

Process for the preparation of new derivatives of 7-aminocephalosporanic acid

Publications (1)

Publication Number
Publication Date

GB1318562A
true

GB1318562A
(en)

1973-05-31

Family
ID=4343150
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB2677970A
Expired

GB1318562A
(en)

1969-06-06
1970-06-03
Manufacture of derivatives of 7-aminocephalosporanic acid

Country Status (11)

Country
Link

US
(1)

US3726865A
(en)

AT
(2)

AT302529B
(en)

AU
(1)

AU1601370A
(en)

BE
(1)

BE751526A
(en)

BR
(1)

BR7019548D0
(en)

CH
(2)

CH524634A
(en)

DE
(1)

DE2025838A1
(en)

FR
(1)

FR2052938A1
(en)

GB
(1)

GB1318562A
(en)

NL
(1)

NL7008237A
(en)

SU
(1)

SU425400A3
(en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4210750A
(en)

1972-07-27
1980-07-01
Merck & Co., Inc.
Process for the preparation of 3-carbamoyl cephalosporins using isocyanates

US4292427A
(en)

1976-11-17
1981-09-29
Merck & Co., Inc.
Cephalosporin compounds

DE3143993A1
(en)

1981-11-05
1983-05-11
Bayer Ag, 5090 Leverkusen

MOLECULAR SCREEN ZEOLITE FOR THE EXTRACTION OF HYDROGEN WITH THE PRESSURE CHANGE ADSORPTION TECHNOLOGY

1969

1969-06-06
CH
CH917071A
patent/CH524634A/en
not_active
IP Right Cessation

1969-06-06
CH
CH865669A
patent/CH524633A/en
not_active
IP Right Cessation

1970

1970-05-27
DE
DE19702025838
patent/DE2025838A1/de
active
Pending

1970-06-02
FR
FR7020214A
patent/FR2052938A1/fr
active
Pending

1970-06-02
US
US00042887A
patent/US3726865A/en
not_active
Expired – Lifetime

1970-06-03
GB
GB2677970A
patent/GB1318562A/en
not_active
Expired

1970-06-05
BR
BR219548/70A
patent/BR7019548D0/en
unknown

1970-06-05
AT
AT793571A
patent/AT302529B/en
not_active
IP Right Cessation

1970-06-05
AT
AT506070A
patent/AT301024B/en
not_active
IP Right Cessation

1970-06-05
BE
BE751526D
patent/BE751526A/en
unknown

1970-06-05
NL
NL7008237A
patent/NL7008237A/xx
unknown

1970-06-05
AU
AU16013/70A
patent/AU1601370A/en
not_active
Expired

1970-06-05
SU
SU1445801A
patent/SU425400A3/ru
active

Also Published As

Publication number
Publication date

AU1601370A
(en)

1971-12-09

DE2025838A1
(en)

1970-12-17

AT301024B
(en)

1972-08-25

CH524633A
(en)

1972-06-30

FR2052938A1
(en)

1971-04-16

SU425400A3
(en)

1974-04-25

BE751526A
(en)

1970-12-07

US3726865A
(en)

1973-04-10

AT302529B
(en)

1972-10-25

CH524634A
(en)

1972-06-30

NL7008237A
(en)

1970-12-08

BR7019548D0
(en)

1973-03-20

Información de contacto