GB1363640A – Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
– Google Patents
GB1363640A – Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
– Google Patents
Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
Info
Publication number
GB1363640A
GB1363640A
GB6202470A
GB6202470A
GB1363640A
GB 1363640 A
GB1363640 A
GB 1363640A
GB 6202470 A
GB6202470 A
GB 6202470A
GB 6202470 A
GB6202470 A
GB 6202470A
GB 1363640 A
GB1363640 A
GB 1363640A
Authority
GB
United Kingdom
Prior art keywords
esters
formula
compound
halogen
atom
Prior art date
1970-12-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6202470A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexachimie SA
Original Assignee
Hexachimie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-12-31
Filing date
1970-12-31
Publication date
1974-08-14
1970-12-31
Application filed by Hexachimie SA
filed
Critical
Hexachimie SA
1970-12-31
Priority to GB6202470A
priority
Critical
patent/GB1363640A/en
1971-12-24
Priority to AU37410/71A
priority
patent/AU3741071A/en
1971-12-27
Priority to CH1897171A
priority
patent/CH537362A/en
1971-12-27
Priority to FR7146813A
priority
patent/FR2120035B1/fr
1971-12-27
Priority to NO4848/71A
priority
patent/NO135982C/no
1971-12-28
Priority to JP398672A
priority
patent/JPS541700B1/ja
1971-12-28
Priority to DE2164988A
priority
patent/DE2164988C3/en
1971-12-28
Priority to BE777347A
priority
patent/BE777347A/en
1971-12-28
Priority to ZA718629A
priority
patent/ZA718629B/en
1971-12-29
Priority to SE7116817A
priority
patent/SE380793B/en
1971-12-30
Priority to AT1125171A
priority
patent/AT315141B/en
1971-12-30
Priority to ES398495A
priority
patent/ES398495A1/en
1971-12-30
Priority to DK645671AA
priority
patent/DK134155B/en
1971-12-30
Priority to US00214473A
priority
patent/US3846436A/en
1971-12-30
Priority to NLAANVRAGE7118162,A
priority
patent/NL177491C/en
1974-03-04
Priority to US05/448,033
priority
patent/US3937832A/en
1974-08-14
Publication of GB1363640A
publication
Critical
patent/GB1363640A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Abstract
1363640 Basic esters of 2,2-diphenylcyclopropane carboxylic acids HEXACHIMIE 30 Dec 1971 [31 Dec 1970] 62024/70 Heading C2C Novel compounds of Formula I in which R is hydrogen, halogen, C 1-4 alkyl or C 1-4 alkoxy, n is zero or 1, and R 1 and R 2 which may be the same or different each denote an alkyl radical or R 1 and R 2 are joined together and, with the nitrogen atom to which they are attached, form a 5- to 7-membered heterocyclic ring which can contain another hetero-atom in addition to the nitrogen and may be optionally substituted by one or more alkyl groups, provided that, if n is 0, R 1 and R 2 are not ethyl, and the salts of these esters with non-toxic acids are prepared by reacting a compound of Formula IV with a compound of formula wherein Z is halogen when Y is OM where M is a metal cation or Z is OH when Y is a halogen atom. Pharmaceutical compositions in conventional forms for oral, rectal or parenteral administration and having anti-tussive activity comprise an above novel compound and a carrier therefor.
GB6202470A
1970-12-31
1970-12-31
Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
Expired
GB1363640A
(en)
Priority Applications (16)
Application Number
Priority Date
Filing Date
Title
GB6202470A
GB1363640A
(en)
1970-12-31
1970-12-31
Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
AU37410/71A
AU3741071A
(en)
1970-12-31
1971-12-24
Esters of 2,2-diaryl-cyclopropane-carboxylic acids
CH1897171A
CH537362A
(en)
1970-12-31
1971-12-27
Process for preparing esters of diaryl-2,2-cyclopropane carboxylic acids
FR7146813A
FR2120035B1
(en)
1970-12-31
1971-12-27
NO4848/71A
NO135982C
(en)
1970-12-31
1971-12-27
JP398672A
JPS541700B1
(en)
1970-12-31
1971-12-28
DE2164988A
DE2164988C3
(en)
1970-12-31
1971-12-28
2,2-Diphenylcyclopropanecarboxylic acid ester derivatives, processes for their preparation and pharmaceuticals containing them
BE777347A
BE777347A
(en)
1970-12-31
1971-12-28
NEW ESTERS OF DIARYL-2,2-CYCLOPROPANE CARBOXYLIC ACIDS
ZA718629A
ZA718629B
(en)
1970-12-31
1971-12-28
Esters of 2.2-diphenyl-cyclopropanecarboxylic acids
SE7116817A
SE380793B
(en)
1970-12-31
1971-12-29
PROCEDURE FOR THE PREPARATION OF 2,2-DIARYLCYCLOPROPANCARBONIC ACID ESTERS
AT1125171A
AT315141B
(en)
1970-12-31
1971-12-30
Process for the preparation of new basic 2,2-diphenylcyclopropanecarboxylic acid esters and their acid addition salts
ES398495A
ES398495A1
(en)
1970-12-31
1971-12-30
Piperidinoethyl and piperidinoethoxyethyl esters of 2,2-diaryl-cyclopropane-carboxylic acids
DK645671AA
DK134155B
(en)
1970-12-31
1971-12-30
Analogous process for the preparation of 2,2-diaryl-cyclopropanecarboxylic acid esters.
US00214473A
US3846436A
(en)
1970-12-31
1971-12-30
Piperidinoethyl and piperidinoethoxyethyl esters of 2,2-diaryl-cyclopropane-carboxylic acids
NLAANVRAGE7118162,A
NL177491C
(en)
1970-12-31
1971-12-30
METHOD FOR PREPARING A PHARMACEUTICAL COMPOSITION WITH ANTI-COUGHT EFFECT AND METHOD FOR PREPARING COMPOUNDS THEREFOR
US05/448,033
US3937832A
(en)
1970-12-31
1974-03-04
Esters of 2,2-diphenyl-cyclopropane-carboxylic acids as cough suppressants
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB6202470A
GB1363640A
(en)
1970-12-31
1970-12-31
Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
Publications (1)
Publication Number
Publication Date
GB1363640A
true
GB1363640A
(en)
1974-08-14
Family
ID=10487788
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB6202470A
Expired
GB1363640A
(en)
1970-12-31
1970-12-31
Esters of 2,2-diphenyl – cyclopropane – carboxylic acids
Country Status (15)
Country
Link
US
(1)
US3846436A
(en)
JP
(1)
JPS541700B1
(en)
AT
(1)
AT315141B
(en)
AU
(1)
AU3741071A
(en)
BE
(1)
BE777347A
(en)
CH
(1)
CH537362A
(en)
DE
(1)
DE2164988C3
(en)
DK
(1)
DK134155B
(en)
ES
(1)
ES398495A1
(en)
FR
(1)
FR2120035B1
(en)
GB
(1)
GB1363640A
(en)
NL
(1)
NL177491C
(en)
NO
(1)
NO135982C
(en)
SE
(1)
SE380793B
(en)
ZA
(1)
ZA718629B
(en)
Families Citing this family (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS604170B2
(en)
*
1974-03-29
1985-02-01
大日本製薬株式会社
Method for producing 1,2-diphenylethanolamine derivative
DE3735712A1
(en)
*
1987-10-22
1989-05-03
Robert Wolff
VICE
Family Cites Families (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FR1313850A
(en)
*
1961-11-09
1963-01-04
Rolland Lab A
New process for the preparation of amino esters derived from propionic acid
US3317526A
(en)
*
1964-07-16
1967-05-02
Astra Ab
Omega-tertiaryamino butynol-1-phenylcycloalkane carboxylates
1970
1970-12-31
GB
GB6202470A
patent/GB1363640A/en
not_active
Expired
1971
1971-12-24
AU
AU37410/71A
patent/AU3741071A/en
not_active
Expired
1971-12-27
CH
CH1897171A
patent/CH537362A/en
not_active
IP Right Cessation
1971-12-27
FR
FR7146813A
patent/FR2120035B1/fr
not_active
Expired
1971-12-27
NO
NO4848/71A
patent/NO135982C/no
unknown
1971-12-28
JP
JP398672A
patent/JPS541700B1/ja
active
Pending
1971-12-28
BE
BE777347A
patent/BE777347A/en
not_active
IP Right Cessation
1971-12-28
DE
DE2164988A
patent/DE2164988C3/en
not_active
Expired
1971-12-28
ZA
ZA718629A
patent/ZA718629B/en
unknown
1971-12-29
SE
SE7116817A
patent/SE380793B/en
unknown
1971-12-30
US
US00214473A
patent/US3846436A/en
not_active
Expired – Lifetime
1971-12-30
DK
DK645671AA
patent/DK134155B/en
not_active
IP Right Cessation
1971-12-30
ES
ES398495A
patent/ES398495A1/en
not_active
Expired
1971-12-30
AT
AT1125171A
patent/AT315141B/en
not_active
IP Right Cessation
1971-12-30
NL
NLAANVRAGE7118162,A
patent/NL177491C/en
not_active
IP Right Cessation
Also Published As
Publication number
Publication date
AT315141B
(en)
1974-05-10
DK134155C
(en)
1977-02-21
BE777347A
(en)
1972-04-17
JPS541700B1
(en)
1979-01-27
NO135982C
(en)
1977-07-06
ZA718629B
(en)
1972-10-25
DE2164988C3
(en)
1982-01-14
DE2164988A1
(en)
1972-07-20
NL7118162A
(en)
1972-07-04
FR2120035B1
(en)
1974-11-15
CH537362A
(en)
1973-05-31
US3846436A
(en)
1974-11-05
NL177491C
(en)
1985-10-01
SE380793B
(en)
1975-11-17
AU3741071A
(en)
1973-06-28
DK134155B
(en)
1976-09-20
FR2120035A1
(en)
1972-08-11
NO135982B
(en)
1977-03-28
DE2164988B2
(en)
1981-03-12
AU465421B2
(en)
1975-09-25
ES398495A1
(en)
1974-08-01
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Legal Events
Date
Code
Title
Description
1974-12-27
PS
Patent sealed [section 19, patents act 1949]
1977-12-30
435
Patent endorsed ‘licences of right’ on the date specified (sect. 35/1949)
1986-08-13
PCNP
Patent ceased through non-payment of renewal fee
