GB1421280A – 3-heterocyclicthiomethylcephalosporins
– Google Patents
GB1421280A – 3-heterocyclicthiomethylcephalosporins
– Google Patents
3-heterocyclicthiomethylcephalosporins
Info
Publication number
GB1421280A
GB1421280A
GB1212575A
GB1212575A
GB1421280A
GB 1421280 A
GB1421280 A
GB 1421280A
GB 1212575 A
GB1212575 A
GB 1212575A
GB 1212575 A
GB1212575 A
GB 1212575A
GB 1421280 A
GB1421280 A
GB 1421280A
Authority
GB
United Kingdom
Prior art keywords
triazolinyl
thiadiazolinyl
thioxo
oxo
nov
Prior art date
1972-11-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1212575A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1972-11-14
Filing date
1973-11-13
Publication date
1976-01-14
1973-11-13
Application filed by SmithKline Corp
filed
Critical
SmithKline Corp
1976-01-14
Publication of GB1421280A
publication
Critical
patent/GB1421280A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
C07D501/36—Methylene radicals, substituted by sulfur atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
Abstract
1421280 3-Heterocyclic-thiomethyl-cephalosporins SMITHKLINE CORP 13 Nov 1973 [14 Nov 1972] 12125/75 Divided out of 1421279 Heading C2C Novel compounds I in which R is H or C 1-4 alkyl, Z is NR or S, A is O or S and M is H, CH 2 -CCl 3 , t-butyl, benzhydryl, benzyloxymethyl, p-nitrophenyl, p-methoxyphenyl or p-methoxybenzyl are prepared by reacting 7-amino-cephalosporanic acid or the corresponding ester thereof with a compound II The heterocyclic substituent in compounds I is 5 – oxo – #
GB1212575A
1972-11-14
1973-11-13
3-heterocyclicthiomethylcephalosporins
Expired
GB1421280A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US306507A
US3868369A
(en)
1972-11-14
1972-11-14
3-heterocyclicthiomethylcephalosporins
Publications (1)
Publication Number
Publication Date
GB1421280A
true
GB1421280A
(en)
1976-01-14
Family
ID=23185613
Family Applications (2)
Application Number
Title
Priority Date
Filing Date
GB1212575A
Expired
GB1421280A
(en)
1972-11-14
1973-11-13
3-heterocyclicthiomethylcephalosporins
GB5265973A
Expired
GB1421279A
(en)
1972-11-14
1973-11-13
3-heterocyclicthiomethylcephalosporins
Family Applications After (1)
Application Number
Title
Priority Date
Filing Date
GB5265973A
Expired
GB1421279A
(en)
1972-11-14
1973-11-13
3-heterocyclicthiomethylcephalosporins
Country Status (6)
Country
Link
US
(1)
US3868369A
(en)
JP
(1)
JPS49133393A
(en)
BE
(1)
BE807011A
(en)
DE
(1)
DE2356704A1
(en)
FR
(1)
FR2206086B1
(en)
GB
(2)
GB1421280A
(en)
Families Citing this family (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4348518A
(en)
1974-05-05
1982-09-07
Hoffmann-La Roche Inc.
Cephalosporins
CH609989A5
(en)
*
1974-06-21
1979-03-30
Hoffmann La Roche
Process for the preparation of acyl derivatives
GB1476981A
(en)
*
1974-06-05
1977-06-16
Bristol Myers Co
Substituted penicillanic acids
PT87616B
(en)
1987-06-24
1992-09-30
Smithkline Beecham Corp
PREPARATION PROCESS OF LEUCOTYREN ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS
Family Cites Families (5)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE1953861C2
(en)
*
1969-10-25
1982-12-23
Fujisawa Pharmaceutical Co., Ltd., Osaka
7-tetrazolylacetamido-3-thiomethyl-3-cephem-4-carboxylic acids
US3766176A
(en)
*
1971-05-11
1973-10-16
R & L Molecular Research Ltd
Certain 7 – (o-aminomethylphenyl-thioacetamido) – 3 – ((heterocyclylthio)methyl)ceph-3-em-4-carboxylic acids
FR2165762A1
(en)
*
1971-12-29
1973-08-10
Fujisawa Pharmaceutical Co
3-(5-mercapto-thiadiazolyl thiomethyl)-7-tetrazolylalkanamido – -3-cephem-4-carboxylic acids – useful as antibacterial agents
US3780032A
(en)
*
1972-02-25
1973-12-18
Bristol Myers Co
7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienylacetamido)-3-(s-(1-methyl-1,2,3-triazol-4-yl)carbonyl)thiomethyl-3-cephem-4-carboxylic acids
US3776906A
(en)
*
1972-03-16
1973-12-04
Bristol Myers Co
7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-thienyl-acetamido))-3-(1,2,5-thiadiazol-3-yl)carbonylthiomethyl-3-cephem-4-carboxylic acids
1972
1972-11-14
US
US306507A
patent/US3868369A/en
not_active
Expired – Lifetime
1973
1973-11-07
BE
BE137487A
patent/BE807011A/en
not_active
IP Right Cessation
1973-11-13
DE
DE2356704A
patent/DE2356704A1/en
not_active
Withdrawn
1973-11-13
GB
GB1212575A
patent/GB1421280A/en
not_active
Expired
1973-11-13
GB
GB5265973A
patent/GB1421279A/en
not_active
Expired
1973-11-14
FR
FR7340542A
patent/FR2206086B1/fr
not_active
Expired
1973-11-14
JP
JP48128116A
patent/JPS49133393A/ja
active
Pending
Also Published As
Publication number
Publication date
FR2206086A1
(en)
1974-06-07
JPS49133393A
(en)
1974-12-21
US3868369A
(en)
1975-02-25
FR2206086B1
(en)
1977-02-18
DE2356704A1
(en)
1974-05-22
GB1421279A
(en)
1976-01-14
BE807011A
(en)
1974-05-07
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Legal Events
Date
Code
Title
Description
1976-05-26
PS
Patent sealed [section 19, patents act 1949]
1985-07-03
PCNP
Patent ceased through non-payment of renewal fee
