GB1525372A – 4-deacetoxyvincristine
– Google Patents
GB1525372A – 4-deacetoxyvincristine
– Google Patents
4-deacetoxyvincristine
Info
Publication number
GB1525372A
GB1525372A
GB7677/77A
GB767777A
GB1525372A
GB 1525372 A
GB1525372 A
GB 1525372A
GB 7677/77 A
GB7677/77 A
GB 7677/77A
GB 767777 A
GB767777 A
GB 767777A
GB 1525372 A
GB1525372 A
GB 1525372A
Authority
GB
United Kingdom
Prior art keywords
compound
deacetoxyvincristine
acid addition
addition salts
deacetoxyvinblastine
Prior art date
1976-02-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7677/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1976-02-24
Filing date
1977-02-23
Publication date
1978-09-20
1977-02-23
Application filed by Richter Gedeon Vegyeszeti Gyar RT
filed
Critical
Richter Gedeon Vegyeszeti Gyar RT
1978-09-20
Publication of GB1525372A
publication
Critical
patent/GB1525372A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P35/00—Antineoplastic agents
Abstract
4-Deacetoxyvincristine and acid addition salts of this compound are obtained by subjecting 4-deacetoxyvinblastine to oxydative formylation and converting the resulting compound where appropriate into its acid addition salts. This compound which can be prepared according to the invention has, for example, excellent cytostatic properties and is less toxic than vincristine, which has similar actions.
GB7677/77A
1976-02-24
1977-02-23
4-deacetoxyvincristine
Expired
GB1525372A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
HU76RI00000586A
HU172183B
(en)
1976-02-24
1976-02-24
Process for producing 4-deacetoxy-vinchristine and acid additional salts
Publications (1)
Publication Number
Publication Date
GB1525372A
true
GB1525372A
(en)
1978-09-20
Family
ID=11000995
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB7677/77A
Expired
GB1525372A
(en)
1976-02-24
1977-02-23
4-deacetoxyvincristine
Country Status (15)
Country
Link
JP
(1)
JPS52102300A
(en)
AT
(1)
AT353429B
(en)
AU
(1)
AU506508B2
(en)
BE
(1)
BE851697A
(en)
CA
(1)
CA1094551A
(en)
CH
(1)
CH627185A5
(en)
DE
(1)
DE2706366A1
(en)
DK
(1)
DK142815B
(en)
FR
(1)
FR2342295A1
(en)
GB
(1)
GB1525372A
(en)
HU
(1)
HU172183B
(en)
IL
(1)
IL51486A
(en)
NL
(1)
NL7701948A
(en)
SE
(1)
SE430694B
(en)
SU
(1)
SU673174A3
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
CN112521408A
(en)
*
2020-12-16
2021-03-19
广州白云山汉方现代药业有限公司
Bisindole alkaloid compound and preparation method and application thereof
CN114933604A
(en)
*
2021-12-10
2022-08-23
广州白云山汉方现代药业有限公司
Vincristine chiral compound impurity and preparation method and application thereof
Families Citing this family (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS5891011A
(en)
*
1981-11-25
1983-05-30
Toshiba Ceramics Co Ltd
Manufacture of silicon nitride powder with high alpha-phase content
1976
1976-02-24
HU
HU76RI00000586A
patent/HU172183B/en
unknown
1977
1977-02-08
SE
SE7701377A
patent/SE430694B/en
not_active
IP Right Cessation
1977-02-09
AT
AT84177A
patent/AT353429B/en
not_active
IP Right Cessation
1977-02-10
AU
AU22173/77A
patent/AU506508B2/en
not_active
Expired
1977-02-10
CH
CH162477A
patent/CH627185A5/en
not_active
IP Right Cessation
1977-02-15
DE
DE19772706366
patent/DE2706366A1/en
not_active
Withdrawn
1977-02-17
IL
IL51486A
patent/IL51486A/en
unknown
1977-02-22
SU
SU772453504A
patent/SU673174A3/en
active
1977-02-22
FR
FR7705059A
patent/FR2342295A1/en
active
Granted
1977-02-22
BE
BE175146A
patent/BE851697A/en
not_active
IP Right Cessation
1977-02-23
JP
JP1824577A
patent/JPS52102300A/en
active
Pending
1977-02-23
CA
CA272,431A
patent/CA1094551A/en
not_active
Expired
1977-02-23
GB
GB7677/77A
patent/GB1525372A/en
not_active
Expired
1977-02-23
NL
NL7701948A
patent/NL7701948A/en
not_active
Application Discontinuation
1977-02-23
DK
DK78777AA
patent/DK142815B/en
not_active
IP Right Cessation
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
CN112521408A
(en)
*
2020-12-16
2021-03-19
广州白云山汉方现代药业有限公司
Bisindole alkaloid compound and preparation method and application thereof
CN114933604A
(en)
*
2021-12-10
2022-08-23
广州白云山汉方现代药业有限公司
Vincristine chiral compound impurity and preparation method and application thereof
Also Published As
Publication number
Publication date
SE7701377L
(en)
1977-08-25
SU673174A3
(en)
1979-07-05
NL7701948A
(en)
1977-08-26
BE851697A
(en)
1977-06-16
IL51486A
(en)
1979-10-31
FR2342295A1
(en)
1977-09-23
CH627185A5
(en)
1981-12-31
DK142815C
(en)
1981-08-24
FR2342295B1
(en)
1980-09-05
AT353429B
(en)
1979-11-12
IL51486A0
(en)
1977-04-29
HU172183B
(en)
1978-06-28
ATA84177A
(en)
1979-04-15
DE2706366A1
(en)
1977-08-25
SE430694B
(en)
1983-12-05
AU506508B2
(en)
1980-01-10
AU2217377A
(en)
1978-08-17
DK78777A
(en)
1977-08-25
DK142815B
(en)
1981-02-02
JPS52102300A
(en)
1977-08-27
CA1094551A
(en)
1981-01-27
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Legal Events
Date
Code
Title
Description
1979-01-10
PS
Patent sealed [section 19, patents act 1949]
1985-10-16
PCNP
Patent ceased through non-payment of renewal fee
