GB2018248A

GB2018248A – Antihypertensive 4 thiazolidine carboxylic acids
– Google Patents

GB2018248A – Antihypertensive 4 thiazolidine carboxylic acids
– Google Patents
Antihypertensive 4 thiazolidine carboxylic acids

Info

Publication number
GB2018248A

GB2018248A
GB7911642A
GB7911642A
GB2018248A
GB 2018248 A
GB2018248 A
GB 2018248A
GB 7911642 A
GB7911642 A
GB 7911642A
GB 7911642 A
GB7911642 A
GB 7911642A
GB 2018248 A
GB2018248 A
GB 2018248A
Authority
GB
United Kingdom
Prior art keywords
antihypertensive
carboxylic acids
thiazolidine carboxylic
thiazolidine
acids
Prior art date
1978-04-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
GB7911642A
Other versions

GB2018248B
(en

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Santen Pharmaceutical Co Ltd

Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1978-04-08
Filing date
1979-04-03
Publication date
1979-10-17

1978-04-08
Priority claimed from JP4163278A
external-priority
patent/JPS54135768A/en

1978-04-25
Priority claimed from JP4965778A
external-priority
patent/JPS54148783A/en

1978-07-03
Priority claimed from JP8111678A
external-priority
patent/JPS557255A/en

1979-04-03
Application filed by Santen Pharmaceutical Co Ltd
filed
Critical
Santen Pharmaceutical Co Ltd

1979-10-17
Publication of GB2018248A
publication
Critical
patent/GB2018248A/en

1982-10-27
Application granted
granted
Critical

1982-10-27
Publication of GB2018248B
publication
Critical
patent/GB2018248B/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

GB7911642A
1978-04-08
1979-04-03
Antihypertensive 4 thiazolidine carboxylic acids

Expired

GB2018248B
(en)

Applications Claiming Priority (3)

Application Number
Priority Date
Filing Date
Title

JP4163278A

JPS54135768A
(en)

1978-04-08
1978-04-08
Thiazolidine derivative

JP4965778A

JPS54148783A
(en)

1978-04-25
1978-04-25
Thiazolidine derivative

JP8111678A

JPS557255A
(en)

1978-07-03
1978-07-03
Thiazolidine derivative

Publications (2)

Publication Number
Publication Date

GB2018248A
true

GB2018248A
(en)

1979-10-17

GB2018248B

GB2018248B
(en)

1982-10-27

Family
ID=27290900
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB7911642A
Expired

GB2018248B
(en)

1978-04-08
1979-04-03
Antihypertensive 4 thiazolidine carboxylic acids

Country Status (11)

Country
Link

US
(5)

US4430344A
(en)

AU
(1)

AU528115B2
(en)

CA
(1)

CA1127157A
(en)

CH
(1)

CH649293A5
(en)

DE
(1)

DE2914059C2
(en)

ES
(1)

ES479410A1
(en)

FR
(1)

FR2421889A1
(en)

GB
(1)

GB2018248B
(en)

IT
(1)

IT1115158B
(en)

NL
(1)

NL7902710A
(en)

SE
(1)

SE434943B
(en)

Cited By (5)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2440365A1
(en)

*

1978-10-31
1980-05-30
Santen Pharmaceutical Co Ltd

NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS

EP0072868A1
(en)

*

1981-02-28
1983-03-02
Santen Pharmaceutical Co., Ltd.
Cyclodextrin clathrate compounds of sulfur-containing compounds

EP0110484A1
(en)

*

1982-12-03
1984-06-13
Simes S.p.A.
Derivatives of aminopyridinecarboxylic acids, methods for their preparation and pharmaceutical compositions containing them

US4745124A
(en)

*

1978-09-11
1988-05-17
University Of Miami
Orally effective anti-hypertensive agents

WO1991013883A1
(en)

*

1990-03-05
1991-09-19
Yason S.R.L.
S-(2-thenoyl)-thiolactic acid derivative having pharmacological activity

Families Citing this family (22)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS56139455A
(en)

*

1980-04-02
1981-10-30
Santen Pharmaceut Co Ltd
Sulfur-containing acylaminoacid

JPS5756425A
(en)

*

1980-09-20
1982-04-05
Santen Pharmaceut Co Ltd
Hypotensor

JPS57112381A
(en)

*

1980-12-29
1982-07-13
Santen Pharmaceut Co Ltd
Five-membered heterocyclic compound

DE3152643A1
(en)

*

1980-12-29
1982-12-16
Santen Pharmaceutical Co Ltd

HETEROCYCLIC 5-MEMBERED RING COMPOUNDS

DE3134933A1
(en)

*

1981-09-03
1983-03-31
Hoechst Ag, 6230 Frankfurt

«UREA DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINES THEREOF AND THE USE THEREOF»

IT1153963B
(en)

*

1982-03-22
1987-01-21
Montedison Spa

ACID DERIVATIVES 2 0 4-THIAZOLIDIN-CARBOXYL 3-ACYL SUBSTITUTED FOR FITOREGULATING AND BIOSTIMULANT ACTION

US4631343A
(en)

*

1983-11-07
1986-12-23
Eli Lilly And Company
Cyanopyrazole intermediates

GB2164333B
(en)

*

1984-07-27
1988-11-16
Boehringer Biochemia Srl
Antitussive and mucus regulating 2-substituted thiazolidines

IT1196485B
(en)

*

1986-07-14
1988-11-16
Zambon Spa

THIAZOLIDIN-4-CARBOXYLIC ACID DERIVATIVES FOR PHARMACEUTICAL ACTIVITIES

CN1030415A
(en)

*

1987-02-20
1989-01-18
山之内制药株式会社
Saturated heterocycle carboxamide derivatives and its preparation method

US5714613A
(en)

*

1995-06-05
1998-02-03
Fujirebio Inc.
Method of producing 2-naphthamide derivative, and compounds for producing 2-naphthamide derivative

US6083966A
(en)

*

1998-08-31
2000-07-04
University Of Florida
Thiazoline acid derivatives

WO2000016763A2
(en)

*

1998-09-21
2000-03-30
University Of Florida Research Foundation, Inc.
Antimalarial agents

US20040132789A1
(en)

*

2002-08-22
2004-07-08
University Of Florida
Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin

US20040044220A1
(en)

*

2002-08-22
2004-03-04
University Of Florida
Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin

US7687468B2
(en)

*

2003-05-14
2010-03-30
Viacell, LLC.
Rejuvenation of stored blood

WO2005034949A1
(en)

*

2003-09-09
2005-04-21
University Of Florida
Desferrithiocin derivatives and their use as iron chelators

AU2006232929B9
(en)

2005-04-04
2009-12-17
University Of Florida Research Foundation, Inc.
Desferrithiocin polyether analogues

CN104003955A
(en)

2007-03-15
2014-08-27
佛罗里达大学研究基金公司
Desferrithiocin polyether analogues

RU2526619C2
(en)

*

2012-12-12
2014-08-27
Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук
Method of obtaining (2r,4r)-2-alkyl-3-(2-mercaptobenzoyl)-1,3-thiazolidine-4-carboxylic acids

AU2014352780A1
(en)

2013-11-22
2016-06-09
University Of Florida Research Foundation, Inc.
Desferrithiocin analogs and uses thereof

WO2016176343A1
(en)

2015-04-27
2016-11-03
University Of Florida Research Foundation, Incorporated
Metabolically programmed metal chelators and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3592905A
(en)

*

1969-10-30
1971-07-13
Merck & Co Inc
Therapeutic methods

FR2356423A1
(en)

*

1976-07-01
1978-01-27
Oeriu Simion
Stone-removing (N)-acyl-(2)-pyridyl-thiazolidine-(4)-carboxylic acids – prepd. by (N)-acylating the (N)-unsubstd. cpds.

AU518147B2
(en)

*

1976-12-03
1981-09-17
E.R. Squibb & Sons, Inc.
Derivatives of thiazolidine, thiazine and morpholine carboxylic acids

US4192878A
(en)

1976-12-03
1980-03-11
E. R. Squibb & Sons, Inc.
Derivatives of thiazolidinecarboxylic acids and related acids

IT1105731B
(en)

*

1977-06-29
1985-11-04
Yoshitomi Pharmaceutical

THIAZOLIDINE COMPOUNDS

JPS5834474B2
(en)

*

1977-06-29
1983-07-27
ウェルファイド株式会社

Method for producing thiazolidine derivatives

JPS6047264B2
(en)

*

1977-08-15
1985-10-21
ウェルファイド株式会社

Thiazolidine derivatives

FR2404635A1
(en)

*

1977-09-28
1979-04-27
Science Union & Cie

NEW THIOPROPRIONYLAMIDES, THEIR OBTAINING PROCEDURES AND THEIR USE IN THERAPEUTICS

US4282235A
(en)

*

1978-05-22
1981-08-04
E. R. Squibb & Sons, Inc.
Derivatives of thiazolidinecarboxylic acids and related acids

US4347371A
(en)

*

1978-12-30
1982-08-31
Santen Pharmaceutical Co., Ltd.
Disulfide compounds

US4374249A
(en)

*

1980-12-23
1983-02-15
American Cyanamid Company
[4R]-3-(ω-Aroylpropionyl)-4-thiazolidinecarboxylic acids and esters

1979

1979-03-23
US
US05/023,397
patent/US4430344A/en
not_active
Expired – Lifetime

1979-03-23
AU
AU45444/79A
patent/AU528115B2/en
not_active
Ceased

1979-04-02
SE
SE7902910A
patent/SE434943B/en
not_active
IP Right Cessation

1979-04-03
GB
GB7911642A
patent/GB2018248B/en
not_active
Expired

1979-04-05
CH
CH3226/79A
patent/CH649293A5/en
not_active
IP Right Cessation

1979-04-06
NL
NL7902710A
patent/NL7902710A/en
not_active
Application Discontinuation

1979-04-06
IT
IT21666/79A
patent/IT1115158B/en
active

1979-04-06
DE
DE2914059A
patent/DE2914059C2/en
not_active
Expired

1979-04-06
ES
ES479410A
patent/ES479410A1/en
not_active
Expired

1979-04-06
FR
FR7908829A
patent/FR2421889A1/en
active
Granted

1979-04-06
CA
CA325,022A
patent/CA1127157A/en
not_active
Expired

1981

1981-03-02
US
US06/239,599
patent/US4457935A/en
not_active
Expired – Fee Related

1981-03-02
US
US06/239,601
patent/US4386096A/en
not_active
Expired – Fee Related

1981-03-02
US
US06/239,602
patent/US4356183A/en
not_active
Expired – Fee Related

1981-03-02
US
US06/239,600
patent/US4423054A/en
not_active
Expired – Fee Related

Cited By (7)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4745124A
(en)

*

1978-09-11
1988-05-17
University Of Miami
Orally effective anti-hypertensive agents

FR2440365A1
(en)

*

1978-10-31
1980-05-30
Santen Pharmaceutical Co Ltd

NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS

EP0072868A1
(en)

*

1981-02-28
1983-03-02
Santen Pharmaceutical Co., Ltd.
Cyclodextrin clathrate compounds of sulfur-containing compounds

EP0072868A4
(en)

*

1981-02-28
1983-07-04
Santen Pharmaceutical Co Ltd
Cyclodextrin clathrate compounds of sulfur-containing compounds.

EP0110484A1
(en)

*

1982-12-03
1984-06-13
Simes S.p.A.
Derivatives of aminopyridinecarboxylic acids, methods for their preparation and pharmaceutical compositions containing them

US4528296A
(en)

*

1982-12-03
1985-07-09
Simes, Societa Italiana Medicinalle Sintetici
Derivatives of aminopyridinecarboxylic acids and pharmaceutical compositions containing them

WO1991013883A1
(en)

*

1990-03-05
1991-09-19
Yason S.R.L.
S-(2-thenoyl)-thiolactic acid derivative having pharmacological activity

Also Published As

Publication number
Publication date

DE2914059C2
(en)

1984-09-06

CA1127157A
(en)

1982-07-06

US4423054A
(en)

1983-12-27

IT1115158B
(en)

1986-02-03

AU4544479A
(en)

1979-10-18

US4356183A
(en)

1982-10-26

US4457935A
(en)

1984-07-03

CH649293A5
(en)

1985-05-15

FR2421889A1
(en)

1979-11-02

FR2421889B1
(en)

1982-11-19

IT7921666D0
(en)

1979-04-06

SE434943B
(en)

1984-08-27

DE2914059A1
(en)

1979-10-25

GB2018248B
(en)

1982-10-27

US4430344A
(en)

1984-02-07

US4386096A
(en)

1983-05-31

ES479410A1
(en)

1980-08-16

SE7902910L
(en)

1979-10-09

AU528115B2
(en)

1983-04-14

NL7902710A
(en)

1979-10-10

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Legal Events

Date
Code
Title
Description

1995-11-29
PCNP
Patent ceased through non-payment of renewal fee

Effective date:
19950403

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