AU2094697A – Polychelants, their complexes with metal ions, their preparation and their uses
– Google Patents
AU2094697A – Polychelants, their complexes with metal ions, their preparation and their uses
– Google Patents
Polychelants, their complexes with metal ions, their preparation and their uses
Info
Publication number
AU2094697A
AU2094697A
AU20946/97A
AU2094697A
AU2094697A
AU 2094697 A
AU2094697 A
AU 2094697A
AU 20946/97 A
AU20946/97 A
AU 20946/97A
AU 2094697 A
AU2094697 A
AU 2094697A
AU 2094697 A
AU2094697 A
AU 2094697A
Authority
AU
Australia
Prior art keywords
polychelants
complexes
preparation
metal ions
ions
Prior art date
1996-03-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU20946/97A
Inventor
Federico Maisano
Marcella Murru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dibra SpA
Original Assignee
Dibra SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1996-03-08
Filing date
1997-03-03
Publication date
1997-09-22
1997-03-03
Application filed by Dibra SpA
filed
Critical
Dibra SpA
1997-09-22
Publication of AU2094697A
publication
Critical
patent/AU2094697A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
A61K51/04—Organic compounds
A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
A61K49/10—Organic compounds
A61K49/12—Macromolecular compounds
A61K49/122—Macromolecular compounds dimers of complexes or complex-forming compounds
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
A61K49/10—Organic compounds
A61K49/12—Macromolecular compounds
A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
A61K49/10—Organic compounds
A61K49/14—Peptides, e.g. proteins
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K49/00—Preparations for testing in vivo
A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
A61K49/10—Organic compounds
A61K49/14—Peptides, e.g. proteins
A61K49/146—Peptides, e.g. proteins the peptide being a polyamino acid, e.g. poly-lysine
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
A61K51/04—Organic compounds
A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
A61K51/04—Organic compounds
A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
C07C229/76—Metal complexes of amino carboxylic acids
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K2123/00—Preparations for testing in vivo
AU20946/97A
1996-03-08
1997-03-03
Polychelants, their complexes with metal ions, their preparation and their uses
Abandoned
AU2094697A
(en)
Applications Claiming Priority (3)
Application Number
Priority Date
Filing Date
Title
ITMI96A0458
1996-03-08
IT96MI000458A
IT1283218B1
(en)
1996-03-08
1996-03-08
POLYKELANTS, THEIR COMPLEXES WITH METALLIC IONS, THEIR PREPARATION AND THEIR USES
PCT/EP1997/001048
WO1997032862A1
(en)
1996-03-08
1997-03-03
Polychelants, their complexes with metal ions, their preparation and their uses
Publications (1)
Publication Number
Publication Date
AU2094697A
true
AU2094697A
(en)
1997-09-22
Family
ID=11373558
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU20946/97A
Abandoned
AU2094697A
(en)
1996-03-08
1997-03-03
Polychelants, their complexes with metal ions, their preparation and their uses
Country Status (7)
Country
Link
US
(1)
US6719958B1
(en)
EP
(2)
EP0885202A1
(en)
JP
(1)
JP2000506152A
(en)
AU
(1)
AU2094697A
(en)
IT
(1)
IT1283218B1
(en)
WO
(1)
WO1997032862A1
(en)
ZA
(1)
ZA971995B
(en)
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Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
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1997-04-18
1999-01-11
Bracco Spa
COMPLEX CHELATES OF PARAMAGNETIC METALS WITH LOW TOXICITY
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1997-04-18
1999-01-11
Bracco Spa
PROCEDURE FOR CONJUGATION OF CHELANTS WITH MOLECULES CONTAINING AMINE GROUPS
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1997-10-27
2004-03-30
Research Corporation Technologies
Magnetic resonance imaging agents for the delivery of therapeutic agents
JP4163381B2
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1997-11-17
2008-10-08
カリフォルニア・インスティテュート・オブ・テクノロジー
Magnetic resonance contrast agents for the detection of physiological agents
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1999-01-15
2000-08-01
Light Sciences Corporation
Noninvasive vascular therapy
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1999-07-29
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Targeting multimeric imaging agents through multilocus binding.
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CONJUGATES OF BILIARY ACIDS WITH COMPLEX CHELATES OF METAL IONS AND THEIR USE.
US6565828B2
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2000-04-07
2003-05-20
Bristol-Myers Squibb Company
Macrocyclic chelants for metallopharmaceuticals
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2000-05-04
2004-01-06
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Functional MRI agents for cancer imaging
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2000-07-17
2002-01-24
California Institute Of Technology
Macrocyclic mri contrast agents
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2000-10-04
2002-04-15
California Institute Of Technology
Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits
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2001-01-09
2003-02-11
Bristol-Myers Squibb Pharma Company
Macrocyclic chelants useful for metallopharmaceuticals
AU2002254000A1
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2001-02-23
2002-09-12
Bristol-Myers Squibb Pharma Company
Labeled macrophage scavenger receptor antagonists for imaging atherosclerosis and vulnerable plaque
TWI221406B
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2001-07-30
2004-10-01
Epix Medical Inc
Systems and methods for targeted magnetic resonance imaging of the vascular system
WO2003024388A2
(en)
2001-09-20
2003-03-27
Cornell Research Foundation, Inc.
Methods and compositions for treating and preventing skin disorders using binding agents specific for psma
EP1369134A1
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2002-06-05
2003-12-10
Bracco Imaging S.p.A.
New agents for magnetic imaging method
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2003-01-10
2010-08-10
Millenium Pharmaceuticals, Inc.
Methods of diagnosing and treating cancer
FR2857967B1
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2003-07-25
2015-04-24
Centre Nat Rech Scient
LANTHANIDE COMPLEXES, THEIR PREPARATION AND USES THEREOF
JP2008508333A
(en)
*
2004-08-05
2008-03-21
ヨハン ウォルフガング ゲーテ−ウニベルジテート フランクフルト アム マイン
Multivalent chelators for modification and organization of target molecules
DE102004038134B4
(en)
2004-08-05
2013-07-25
Johann Wolfgang Goethe-Universität Frankfurt am Main
Multivalent chelators for modifying and organizing target molecules, methods for their preparation and their use
FR2883562B1
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2005-03-24
2009-02-27
Guerbet Sa
LIPOPHILIC CHELATES AND THEIR USE IN IMAGING
JP5064761B2
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2005-12-21
2012-10-31
富士フイルム株式会社
Higher fatty acid triesters and amide derivatives having diethylenetriamine type metal chelate structure
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2009-04-13
2012-05-30
法国健康和医学研究院
Hpv particles and uses thereof
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2009-12-16
2011-06-29
Bracco Imaging S.p.A
Process for the preparation of chelated compounds
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Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
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2013-08-01
2017-06-07
Rochester Institute of Technology
Modular imaging agents containing amino acids and peptides
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Virus-like particle conjugates for treatment of tumors
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Bayer Pharma Aktiengesellschaft
New gadolinium chelate compounds for use in magnetic resonance imaging
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Aleta Biotherapeutics, Inc.
Targeted cancer therapy
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2016-09-07
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Compositions and methods for treatment of insulin resistance
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2016-11-28
2018-05-31
Bayer Pharma Aktiengesellschaft
High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
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テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイションＴｅｍｐｌｅ Ｕｎｉｖｅｒｓｉｔｙ−Ｏｆ Ｔｈｅ Ｃｏｍｍｏｎｗｅａｌｔｈ Ｓｙｓｔｅｍ Ｏｆ Ｈｉｇｈｅｒ Ｅｄｕｃａｔｉｏｎ
Compositions and Methods for Treating Insulin Resistance
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コリア アトミック エナジー リサーチ インスティテュートＫｏｒｅａ Ａｔｏｍｉｃ Ｅｎｅｒｇｙ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ
Radioactive element labeling method, radioactive labeling compound, and radioactive element labeling kit containing it
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2022-09-21
Bayer Aktiengesellschaft
New contrast agent for use in magnetic resonance imaging
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(en)
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1986-04-11
1988-12-16
Guerbet Sa
GYSOLINIUM-DOTA COMPLEX LYSINE SALT AND ITS APPLICATIONS TO DIAGNOSIS
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Macrocyclic polyaza dichelates linked through ring nitrogens via an amide or ester functionality
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Aromatic amide compounds and their chelates
1996
1996-03-08
IT
IT96MI000458A
patent/IT1283218B1/en
active
IP Right Grant
1997
1997-03-03
EP
EP97906153A
patent/EP0885202A1/en
not_active
Ceased
1997-03-03
WO
PCT/EP1997/001048
patent/WO1997032862A1/en
not_active
Application Discontinuation
1997-03-03
JP
JP9531441A
patent/JP2000506152A/en
active
Pending
1997-03-03
EP
EP01118591A
patent/EP1151997A1/en
not_active
Withdrawn
1997-03-03
AU
AU20946/97A
patent/AU2094697A/en
not_active
Abandoned
1997-03-07
ZA
ZA9701995A
patent/ZA971995B/en
unknown
2000
2000-09-11
US
US09/659,593
patent/US6719958B1/en
not_active
Expired – Fee Related
Also Published As
Publication number
Publication date
ITMI960458D0
(en)
1996-03-08
EP1151997A1
(en)
2001-11-07
US6719958B1
(en)
2004-04-13
EP0885202A1
(en)
1998-12-23
WO1997032862A1
(en)
1997-09-12
ITMI960458A1
(en)
1997-09-08
JP2000506152A
(en)
2000-05-23
IT1283218B1
(en)
1998-04-16
ZA971995B
(en)
1998-06-23
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