AU2332188A – Compounds having antiprogestational and anti-estrogenic activities for the treatment of hormone-dependent tumors
– Google Patents
AU2332188A – Compounds having antiprogestational and anti-estrogenic activities for the treatment of hormone-dependent tumors
– Google Patents
Compounds having antiprogestational and anti-estrogenic activities for the treatment of hormone-dependent tumors
Info
Publication number
AU2332188A
AU2332188A
AU23321/88A
AU2332188A
AU2332188A
AU 2332188 A
AU2332188 A
AU 2332188A
AU 23321/88 A
AU23321/88 A
AU 23321/88A
AU 2332188 A
AU2332188 A
AU 2332188A
AU 2332188 A
AU2332188 A
AU 2332188A
Authority
AU
Australia
Prior art keywords
hormone
treatment
antiprogestational
compounds
dependent tumors
Prior art date
1987-10-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU23321/88A
Other versions
AU624082B2
(en
Inventor
Sybille Dr. Beier
Krysztof Dr. Chwalisz
Walter Dr. Elger
Marianne Fahnrich
Syed Hamiduddin Dr. Hasan
Beate Kosub
Martin Dr. Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1987-10-01
Filing date
1988-09-30
Publication date
1989-04-20
1988-09-30
Application filed by Schering AG
filed
Critical
Schering AG
1989-04-20
Publication of AU2332188A
publication
Critical
patent/AU2332188A/en
1992-06-04
Application granted
granted
Critical
1992-06-04
Publication of AU624082B2
publication
Critical
patent/AU624082B2/en
2008-09-30
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P13/00—Drugs for disorders of the urinary system
A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P15/00—Drugs for genital or sexual disorders; Contraceptives
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P35/00—Antineoplastic agents
Abstract
Agents, containing at least one compound having antiprogestational activity and at least one compound having anti-estrogenic activity, are suitable for the treatment of hormone-dependent tumors.
AU23321/88A
1987-10-01
1988-09-30
Compounds having antiprogestational and anti-estrogenic activities for the treatment of hormone-dependent tumors
Ceased
AU624082B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19873733478
DE3733478A1
(en)
1987-10-01
1987-10-01
ANTIGESTAGEN AND ANTIOOTROGENIC COMPOUNDS FOR THE INTRODUCTION OF BIRTH AND PREGNANCY, AND THE TREATMENT OF GYNAECOLOGICAL DISORDER AND HORMONE-RELATED TUMORS
DE3733478
1987-10-01
Publications (2)
Publication Number
Publication Date
AU2332188A
true
AU2332188A
(en)
1989-04-20
AU624082B2
AU624082B2
(en)
1992-06-04
Family
ID=6337559
Family Applications (2)
Application Number
Title
Priority Date
Filing Date
AU23322/88A
Ceased
AU616208B2
(en)
1987-10-01
1988-09-30
Compounds having antiprogestational and anti-estrogenic activities for induction of labor and for termination of pregnancy, as well as for the treatment of gynaecological disorders
AU23321/88A
Ceased
AU624082B2
(en)
1987-10-01
1988-09-30
Compounds having antiprogestational and anti-estrogenic activities for the treatment of hormone-dependent tumors
Family Applications Before (1)
Application Number
Title
Priority Date
Filing Date
AU23322/88A
Ceased
AU616208B2
(en)
1987-10-01
1988-09-30
Compounds having antiprogestational and anti-estrogenic activities for induction of labor and for termination of pregnancy, as well as for the treatment of gynaecological disorders
Country Status (14)
Country
Link
US
(2)
US4888331A
(en)
EP
(1)
EP0310541B1
(en)
JP
(2)
JP2656958B2
(en)
AT
(2)
ATE83149T1
(en)
AU
(2)
AU616208B2
(en)
CA
(2)
CA1329126C
(en)
DE
(3)
DE3733478A1
(en)
DK
(2)
DK550088A
(en)
ES
(2)
ES2055745T3
(en)
GR
(1)
GR3007225T3
(en)
IE
(2)
IE65165B1
(en)
IL
(2)
IL87886A
(en)
PH
(1)
PH26774A
(en)
ZA
(2)
ZA887379B
(en)
Families Citing this family (47)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FR2654337B1
(en)
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1989-11-15
1994-08-05
Roussel Uclaf
NOVEL BIODEGRADABLE INJECTABLE MICROSPHERES PREPARATION METHOD AND INJECTABLE SUSPENSIONS CONTAINING THEM.
DE4329344A1
(en)
*
1993-08-27
1995-03-02
Schering Ag
Progesterone antagonist and anti-estrogenic compounds for the treatment of Leiomyomata uteri
DE4335876A1
(en)
*
1993-10-17
1995-04-20
Schering Ag
Combination of progesterone antagonists and partial agonist antiestrogens for hormone replacement therapy for peri- and postmenopausal women
GB9410533D0
(en)
*
1994-05-26
1994-07-13
Lynxvale Ltd
In situ hybridisation and immuno-Chemical localisation of a growth factor
DE4426601A1
(en)
*
1994-07-27
1996-02-01
Schering Ag
Use of a combination product containing a competitive progesterone antagonist and a progestogen for the manufacture of a medicament for the treatment of endometriosis or Leiomyomata uteri
ZA9510926B
(en)
1994-12-23
1996-07-03
Schering Ag
Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
DE19706061A1
(en)
1997-02-07
1998-08-13
Schering Ag
Anti-gestagen effective steroids with fluorinated 17alpha alkyl chain
US6653297B1
(en)
*
1997-07-03
2003-11-25
Medical College Of Hampton Roads
Control of selective estrogen receptor modulators
DE19739916C2
(en)
*
1997-09-11
2001-09-13
Hesch Rolf Dieter
Use of a combination of a progestogen and an estrogen for the continuous inhibition of ovulation and possibly simultaneous treatment and / or prophylaxis of tumors of the mammary glands
US6355648B1
(en)
*
1999-05-04
2002-03-12
American Home Products Corporation
Thio-oxindole derivatives
US6462032B1
(en)
1999-05-04
2002-10-08
Wyeth
Cyclic regimens utilizing indoline derivatives
US6369056B1
(en)
1999-05-04
2002-04-09
American Home Products Corporation
Cyclic urea and cyclic amide derivatives
US6417214B1
(en)
*
1999-05-04
2002-07-09
Wyeth
3,3-substituted indoline derivatives
JP5005127B2
(en)
1999-05-04
2012-08-22
ストラカン・インターナショナル・リミテッド
Androgenic glycosides and their androgenic activity
US6380178B1
(en)
*
1999-05-04
2002-04-30
American Home Products Corporation
Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6380235B1
(en)
1999-05-04
2002-04-30
American Home Products Corporation
Benzimidazolones and analogues
US6339098B1
(en)
1999-05-04
2002-01-15
American Home Products Corporation
2,1-benzisothiazoline 2,2-dioxides
US6329416B1
(en)
1999-05-04
2001-12-11
American Home Products Corporation
Combination regimens using 3,3-substituted indoline derivatives
US6319912B1
(en)
*
1999-05-04
2001-11-20
American Home Products Corporation
Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6391907B1
(en)
1999-05-04
2002-05-21
American Home Products Corporation
Indoline derivatives
US6509334B1
(en)
1999-05-04
2003-01-21
American Home Products Corporation
Cyclocarbamate derivatives as progesterone receptor modulators
AU4980100A
(en)
*
1999-05-04
2000-11-17
American Home Products Corporation
Compositions containing benzimidazolones and progestogens
US6498154B1
(en)
1999-05-04
2002-12-24
Wyeth
Cyclic regimens using quinazolinone and benzoxazine derivatives
US6399593B1
(en)
*
1999-05-04
2002-06-04
Wyeth
Cyclic regimens using cyclic urea and cyclic amide derivatives
CA2372773A1
(en)
*
1999-05-04
2000-11-09
American Home Products Corporation
Contraceptive compositions containing antiprogestinic and progestinic
US6444668B1
(en)
1999-05-04
2002-09-03
Wyeth
Combination regimens using progesterone receptor modulators
US6407101B1
(en)
*
1999-05-04
2002-06-18
American Home Products Corporation
Cyanopyrroles
US6358948B1
(en)
1999-05-04
2002-03-19
American Home Products Corporation
Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6436929B1
(en)
*
1999-05-04
2002-08-20
Wyeth
Cyclothiocarbamate derivatives as progesterone receptor modulators
US6423699B1
(en)
1999-05-04
2002-07-23
American Home Products Corporation
Combination therapies using benzimidazolones
US6358947B1
(en)
1999-05-04
2002-03-19
American Home Products Corporation
Tetracyclic progesterone receptor modulator compounds and methods
US6306851B1
(en)
1999-05-04
2001-10-23
American Home Products Corporation
Cyclocarbamate and cyclic amide derivatives
GB0000313D0
(en)
2000-01-10
2000-03-01
Astrazeneca Uk Ltd
Formulation
HU0301276A2
(en)
*
2000-10-06
2003-11-28
Biomedicines, Inc.
Combination therapy for the treatment of estrogen-sensitive disease
CZ299942B6
(en)
*
2000-10-18
2008-12-29
Schering Aktiengesellschaft
Pharmaceutical compositions containing antiprogestin for prevention and treatment of hormone-dependent diseases
US6599921B2
(en)
2001-02-22
2003-07-29
Nanodesign, Inc.
Non-steroidal estrogen receptor ligands
US20030013694A1
(en)
*
2001-05-25
2003-01-16
Jens Hoffmann
Use and compositions of antiprogestins for treatment of prostate diseases
UY27301A1
(en)
*
2001-05-25
2003-02-28
Schering Ag
USE AND COMPOSITIONS OF ANTIPROGESTINES FOR THE TREATMENT OF PROSTATE DISEASES
GB0120147D0
(en)
*
2001-08-17
2001-10-10
Metris Therapeutics Ltd
Treatment method
DE10159217A1
(en)
*
2001-11-27
2003-06-05
Schering Ag
17alpha-alkyl-17ß-oxy-estratrienes and intermediates for their preparation, use of 17alpha-alkyl-17ß-oxy-estratriene for the preparation of medicaments and pharmaceutical preparations
JP2006521381A
(en)
*
2003-02-28
2006-09-21
デック−テク インコーポレーティッド
Resonance modulators for diagnosis and treatment
US20040242551A1
(en)
*
2003-05-28
2004-12-02
Schering Ag
Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
CA2582669A1
(en)
*
2004-10-04
2006-04-20
Wayne State University
Use of aromatase inhibitors for the treatment of ectopic pregnancy
US20100087407A1
(en)
*
2006-08-04
2010-04-08
James Symons
use of aromatase inhibitors
US7694688B2
(en)
2007-01-05
2010-04-13
Applied Materials, Inc.
Wet clean system design
US20100292150A1
(en)
*
2007-12-10
2010-11-18
Meditrina Pharmaceuticals, Inc.
Treatment of Menorrhagia with Aromatase Inhibitor
US20100087402A1
(en)
*
2008-09-29
2010-04-08
Vivus, Inc.
Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders
Family Cites Families (13)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4656187A
(en)
*
1981-08-03
1987-04-07
Eli Lilly And Company
Treatment of mammary cancer
IL68222A
(en)
*
1983-03-24
1987-02-27
Yeda Res & Dev
Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
DE3323321A1
(en)
*
1983-06-24
1985-01-03
Schering AG, 1000 Berlin und 4709 Bergkamen
PROPHYLAXIS AND THERAPY OF CORONARY HEART DISEASES BY LOWERING THE OESTROGEN LEVEL
GB8327256D0
(en)
*
1983-10-12
1983-11-16
Ici Plc
Steroid derivatives
DE3337450A1
(en)
*
1983-10-12
1985-04-25
Schering AG, 1000 Berlin und 4709 Bergkamen
PROSTAGLANDINE AND ANTIGESTAGE FOR PREGNANCY ABORT
US4666885A
(en)
*
1985-02-08
1987-05-19
Fernand Labrie
Combination therapy for treatment of female breast cancer
US4760053A
(en)
*
1984-08-02
1988-07-26
Fernand Labrie
Combination therapy for selected sex steroid dependent cancers
US4775660A
(en)
*
1984-08-02
1988-10-04
Fernand Labrie
Treatment of breast cancer by combination therapy
DE3586053D1
(en)
*
1984-08-02
1992-06-17
Labrie
PHARMACEUTICAL COMPOSITION FOR THE COMBINATION THERAPY OF HORMONE-DEPENDENT CANCER.
US4732904A
(en)
*
1984-12-24
1988-03-22
Morgan Lee R
Antiestrogenic hydrazones
DE3533175A1
(en)
*
1985-09-13
1987-03-19
Schering Ag
ANTIGESTAGES TO SHIFT ENDOMETRIAL MATURATION
FR2598083B1
(en)
*
1986-05-05
1989-12-29
Theramex Laboratoire
NOVEL PHARMACEUTICAL COMPOSITIONS WITH ANTIPROGESTERONIC ACTION AND PROCESS FOR OBTAINING SAME
DE3633244A1
(en)
*
1986-09-26
1988-03-31
Schering Ag
ANTIGESTAGE FOR INHIBITING UTERINE PROSTAGLAND INSYNTHESIS
1987
1987-10-01
DE
DE19873733478
patent/DE3733478A1/en
not_active
Withdrawn
1988
1988-09-28
JP
JP63241208A
patent/JP2656958B2/en
not_active
Expired – Fee Related
1988-09-28
JP
JP63241207A
patent/JP2620333B2/en
not_active
Expired – Fee Related
1988-09-30
DK
DK550088A
patent/DK550088A/en
not_active
Application Discontinuation
1988-09-30
PH
PH37621A
patent/PH26774A/en
unknown
1988-09-30
IE
IE295388A
patent/IE65165B1/en
not_active
IP Right Cessation
1988-09-30
EP
EP88730221A
patent/EP0310541B1/en
not_active
Expired – Lifetime
1988-09-30
ZA
ZA887379A
patent/ZA887379B/en
unknown
1988-09-30
DE
DE8888730221T
patent/DE3876582D1/en
not_active
Expired – Lifetime
1988-09-30
ES
ES88730222T
patent/ES2055745T3/en
not_active
Expired – Lifetime
1988-09-30
AU
AU23322/88A
patent/AU616208B2/en
not_active
Ceased
1988-09-30
ZA
ZA887378A
patent/ZA887378B/en
unknown
1988-09-30
IL
IL87886A
patent/IL87886A/en
active
Protection Beyond IP Right Term
1988-09-30
CA
CA000579023A
patent/CA1329126C/en
not_active
Expired – Fee Related
1988-09-30
IL
IL87885A
patent/IL87885A/en
active
Protection Beyond IP Right Term
1988-09-30
IE
IE295488A
patent/IE66335B1/en
not_active
IP Right Cessation
1988-09-30
AT
AT88730221T
patent/ATE83149T1/en
not_active
IP Right Cessation
1988-09-30
DK
DK550188A
patent/DK550188A/en
not_active
Application Discontinuation
1988-09-30
DE
DE3850026T
patent/DE3850026D1/en
not_active
Expired – Lifetime
1988-09-30
CA
CA000579022A
patent/CA1330039C/en
not_active
Expired – Fee Related
1988-09-30
AU
AU23321/88A
patent/AU624082B2/en
not_active
Ceased
1988-09-30
AT
AT88730222T
patent/ATE106730T1/en
not_active
IP Right Cessation
1988-09-30
ES
ES88730221T
patent/ES2053795T3/en
not_active
Expired – Lifetime
1988-10-03
US
US07/252,299
patent/US4888331A/en
not_active
Expired – Lifetime
1993
1993-03-05
GR
GR920402867T
patent/GR3007225T3/el
unknown
1994
1994-02-14
US
US08/195,046
patent/US5733902A/en
not_active
Expired – Fee Related
Also Published As
Publication number
Publication date
IE882954L
(en)
1989-04-01
CA1330039C
(en)
1994-06-07
ES2053795T3
(en)
1994-08-01
PH26774A
(en)
1992-09-28
DK550188A
(en)
1989-04-02
AU616208B2
(en)
1991-10-24
IL87885A
(en)
1993-06-10
ATE83149T1
(en)
1992-12-15
DK550088A
(en)
1989-04-02
ZA887378B
(en)
1989-05-30
ZA887379B
(en)
1989-05-30
AU624082B2
(en)
1992-06-04
IE66335B1
(en)
1995-12-27
AU2332288A
(en)
1989-06-08
US4888331A
(en)
1989-12-19
DK550188D0
(en)
1988-09-30
DK550088D0
(en)
1988-09-30
IL87886A
(en)
1993-06-10
CA1329126C
(en)
1994-05-03
IE65165B1
(en)
1995-10-04
GR3007225T3
(en)
1993-07-30
US5733902A
(en)
1998-03-31
DE3876582D1
(en)
1993-01-21
DE3850026D1
(en)
1995-07-06
EP0310541A1
(en)
1989-04-05
DE3733478A1
(en)
1989-04-13
ES2055745T3
(en)
1994-09-01
IL87886A0
(en)
1989-03-31
EP0310541B1
(en)
1992-12-09
ATE106730T1
(en)
1994-06-15
IE882953L
(en)
1989-04-01
JP2620333B2
(en)
1997-06-11
IL87885A0
(en)
1989-03-31
JP2656958B2
(en)
1997-09-24
JPH01106823A
(en)
1989-04-24
JPH01106822A
(en)
1989-04-24
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Legal Events
Date
Code
Title
Description
2004-04-29
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
