AU2553384A

AU2553384A – Benzidene derivatives as peroxidase indicator
– Google Patents

AU2553384A – Benzidene derivatives as peroxidase indicator
– Google Patents
Benzidene derivatives as peroxidase indicator

Info

Publication number
AU2553384A

AU2553384A
AU25533/84A
AU2553384A
AU2553384A
AU 2553384 A
AU2553384 A
AU 2553384A
AU 25533/84 A
AU25533/84 A
AU 25533/84A
AU 2553384 A
AU2553384 A
AU 2553384A
AU 2553384 A
AU2553384 A
AU 2553384A
Authority
AU
Australia
Prior art keywords
group
alkyl
chromogenic
stands
chem
Prior art date
1983-03-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU25533/84A
Other versions

AU569065B2
(en

Inventor
Dierck Lentfer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mallinckrodt Diagnostica Germany GmbH

Original Assignee
Byk Mallinckrodt Chemische Produkte GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1983-03-31
Filing date
1984-03-09
Publication date
1984-10-04

1984-03-09
Application filed by Byk Mallinckrodt Chemische Produkte GmbH
filed
Critical
Byk Mallinckrodt Chemische Produkte GmbH

1984-10-04
Publication of AU2553384A
publication
Critical
patent/AU2553384A/en

1988-01-21
Application granted
granted
Critical

1988-01-21
Publication of AU569065B2
publication
Critical
patent/AU569065B2/en

2004-03-09
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES

C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions

C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase

C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES

C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes

C12Q2326/10—Benzidines

C12Q2326/12—3,3′,5,5′-Tetramethylbenzidine, i.e. TMB

Abstract

An improved determination of peroxidase activity by end dilution titration is carried out with a benzidine derivative of the general formula I where R1 stands for a hydrogen atom, a halogen atom, an amino group, a (C1-C4) alkyl group, a (C1-C4) alkoxy group, a carboxy group, a sulfo group or a carboxypropyloxy group and where R2 stands for a hydrogen atom, a halogen atom, a (C1-C4) alkyl group, or a salt of this benzidine compound, in the presence of a non-chromogenic or low-chromogenic phenylene derivative of the general formula II where R3 and R4 are equal or different and stand for a hydroxy group or an amino group, a (C1-C4) alkyl amino group or a benzylamino group.

AU25533/84A
1983-03-31
1984-03-09
Benzidene derivatives as peroxidase indicator

Ceased

AU569065B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

DE19833311887

DE3311887A1
(en)

1983-03-31
1983-03-31

METHOD FOR DETERMINING PEROXIDASE ACTIVITY BY FINAL DILUTION TITRATION AND MEANS FOR CARRYING OUT THE METHOD

DE3311887

1983-03-31

Publications (2)

Publication Number
Publication Date

AU2553384A
true

AU2553384A
(en)

1984-10-04

AU569065B2

AU569065B2
(en)

1988-01-21

Family
ID=6195285
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU25533/84A
Ceased

AU569065B2
(en)

1983-03-31
1984-03-09
Benzidene derivatives as peroxidase indicator

Country Status (6)

Country
Link

EP
(1)

EP0123902B1
(en)

AT
(1)

ATE67519T1
(en)

AU
(1)

AU569065B2
(en)

CA
(1)

CA1216216A
(en)

DE
(2)

DE3311887A1
(en)

ES
(1)

ES8501800A1
(en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS6152300A
(en)

*

1984-08-22
1986-03-14
Eiken Kagaku Kk
Composition for measuring hydrogen peroxide

EP0196743A3
(en)

*

1985-01-31
1988-10-19
Savyon Diagnostics Ltd.
Stable chemical compositions containing chromogenic materials and peroxides, and method for obtaining them

IL74205A
(en)

*

1985-01-31
1990-01-18
Savyon Diagnostics Ltd
Method for carrying out enzyme assays utilizing stable chemical compositions containing hydrogen peroxide and a chromogen

GB8505899D0
(en)

*

1985-03-07
1985-04-11
Boots Celltech Diagnostics
Assay reagents

US4837395A
(en)

*

1985-05-10
1989-06-06
Syntex (U.S.A.) Inc.
Single step heterogeneous assay

EP0210863A1
(en)

*

1985-07-29
1987-02-04
Modern Diagnostics, Inc.
Immunoassay

US5017475A
(en)

*

1985-11-25
1991-05-21
Microbiological Associates, Inc.
Fluorescent detection method based on enzyme activated conversion of a fluorophore precursor substrate

EP0243126B1
(en)

*

1986-04-19
1992-08-12
Sanwa Kagaku Kenkyusho Co., Ltd.
Method of measuring hydrogen peroxide or of measuring an enzyme or biochemical substrate liberating the peroxide

EP0243125B1
(en)

*

1986-04-19
1992-08-12
Sanwa Kagaku Kenkyusho Co., Ltd.
Method of measuring phenol and alpha-naphthol, and method of measuring the activity of enzymes

US4828983A
(en)

*

1986-07-10
1989-05-09
Eastman Kodak Company
Use of phenols and anilines to increase the rate of peroxidase catalyzed oxidation of leuco dyes

IL82840A0
(en)

*

1986-07-15
1987-12-20
Savyon Diagnostics Ltd
Method and compositions for the determination of occult blood

US5532138A
(en)

*

1990-04-26
1996-07-02
Behringwerke Ag
Method and kits for determining peroxidatively active catalysts

US5332662A
(en)

*

1992-07-31
1994-07-26
Syntex (U.S.A.) Inc.
Methods for determining peroxidatively active substances

GB9512994D0
(en)

*

1995-06-26
1995-08-30
Brf International
Method for quantitative measurement of an enzyme linked immunosorbent assay

US5846754A
(en)

*

1996-05-28
1998-12-08
Bayer Corporation
Enzyme determination with protease inactivation

Family Cites Families (7)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US2905594A
(en)

*

1956-04-25
1959-09-22
Herman J Morris
Means for detecting enzyme activity

NL277911A
(en)

*

1961-05-04

DE2460903C3
(en)

*

1974-12-21
1981-12-24
Boehringer Mannheim Gmbh, 6800 Mannheim

New 3,3 ‘, 5,5’-Tetraalkylbenzidines

IL51668A
(en)

*

1977-03-16
1981-12-31
Israel State
Analytical method for the quantitative determination of immunogens and antibodies and a kit therefor

US4279993A
(en)

*

1979-11-13
1981-07-21
Magers Thomas A
Indicator composition and test device containing amine oxide, and method of use

DE3311889A1
(en)

*

1983-03-31
1984-10-11
Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach

METHOD FOR IRREVERSIBLE BINDING OF PROTEIN TO POLYSTYROL SURFACES WITH THE PRESERVATION OF BIOLOGICAL ACTIVITY, POLYSTYROL SURFACES OBTAINED AND THEIR USE

EP0121191A2
(en)

*

1983-04-04
1984-10-10
Miles Laboratories, Inc.
Analytical test composition, device, method for its preparation and method for the determination of peroxidatively active substances

1983

1983-03-31
DE
DE19833311887
patent/DE3311887A1/en
not_active
Ceased

1984

1984-03-08
CA
CA000449175A
patent/CA1216216A/en
not_active
Expired

1984-03-09
AU
AU25533/84A
patent/AU569065B2/en
not_active
Ceased

1984-03-27
AT
AT84103368T
patent/ATE67519T1/en
not_active
IP Right Cessation

1984-03-27
EP
EP84103368A
patent/EP0123902B1/en
not_active
Expired – Lifetime

1984-03-27
DE
DE8484103368T
patent/DE3485068D1/en
not_active
Expired – Fee Related

1984-03-30
ES
ES531183A
patent/ES8501800A1/en
not_active
Expired

Also Published As

Publication number
Publication date

EP0123902A2
(en)

1984-11-07

ATE67519T1
(en)

1991-10-15

DE3311887A1
(en)

1984-12-20

EP0123902B1
(en)

1991-09-18

ES531183A0
(en)

1984-12-01

CA1216216A
(en)

1987-01-06

DE3485068D1
(en)

1991-10-24

ES8501800A1
(en)

1984-12-01

EP0123902A3
(en)

1987-06-16

AU569065B2
(en)

1988-01-21

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