AU2769689A

AU2769689A – Pharmaceutical preparation for the treatment of hypertension using a potassium channel activator and a B-blocker antihypertensive agent
– Google Patents

AU2769689A – Pharmaceutical preparation for the treatment of hypertension using a potassium channel activator and a B-blocker antihypertensive agent
– Google Patents
Pharmaceutical preparation for the treatment of hypertension using a potassium channel activator and a B-blocker antihypertensive agent

Info

Publication number
AU2769689A

AU2769689A
AU27696/89A
AU2769689A
AU2769689A
AU 2769689 A
AU2769689 A
AU 2769689A
AU 27696/89 A
AU27696/89 A
AU 27696/89A
AU 2769689 A
AU2769689 A
AU 2769689A
AU 2769689 A
AU2769689 A
AU 2769689A
Authority
AU
Australia
Prior art keywords
hypertension
antihypertensive agent
potassium channel
treatment
pharmaceutical preparation
Prior art date
1988-01-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU27696/89A
Other versions

AU614008B2
(en

Inventor
Robin Edwin Buckingham
John Morris Evans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Beecham Group PLC

Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1988-01-06
Filing date
1989-01-04
Publication date
1989-07-06
Family has litigation

First worldwide family litigation filed
litigation
Critical
https://patents.darts-ip.com/?family=10629550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2769689(A)
«Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1989-01-04
Application filed by Beecham Group PLC
filed
Critical
Beecham Group PLC

1989-07-06
Publication of AU2769689A
publication
Critical
patent/AU2769689A/en

1991-08-15
Application granted
granted
Critical

1991-08-15
Publication of AU614008B2
publication
Critical
patent/AU614008B2/en

2009-01-04
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 – A61K41/00

A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin

A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/12—Antihypertensives

Abstract

A pharmaceutical product comprising a potassium channel activator antihypertensive agent and a beta -blocker antihypertensive agent as a combined preparation for simultaneous, separate or sequential use in therapy of hypertension.

AU27696/89A
1988-01-06
1989-01-04
Pharmaceutical preparation for the treatment of hypertension using a potassium channel activator and a b-blocker antihypertensive agent

Ceased

AU614008B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

GB888800199A

GB8800199D0
(en)

1988-01-06
1988-01-06
Pharmaceutical preparation

GB8800199

1988-01-06

Publications (2)

Publication Number
Publication Date

AU2769689A
true

AU2769689A
(en)

1989-07-06

AU614008B2

AU614008B2
(en)

1991-08-15

Family
ID=10629550
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU27696/89A
Ceased

AU614008B2
(en)

1988-01-06
1989-01-04
Pharmaceutical preparation for the treatment of hypertension using a potassium channel activator and a b-blocker antihypertensive agent

Country Status (15)

Country
Link

US
(1)

US5032591A
(en)

EP
(1)

EP0323745B1
(en)

JP
(1)

JPH01224316A
(en)

KR
(1)

KR890011591A
(en)

AT
(1)

ATE83375T1
(en)

AU
(1)

AU614008B2
(en)

CA
(1)

CA1317228C
(en)

DE
(1)

DE3876773T2
(en)

DK
(1)

DK2689A
(en)

ES
(1)

ES2042776T3
(en)

GB
(1)

GB8800199D0
(en)

GR
(1)

GR3006857T3
(en)

NZ
(1)

NZ227518A
(en)

PT
(1)

PT89388B
(en)

ZA
(1)

ZA8944B
(en)

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU642961B2
(en)

*

1990-02-13
1993-11-04
Merck Patent Gesellschaft Mit Beschrankter Haftung
Pharmaceutical composition

US5552443A
(en)

*

1990-08-30
1996-09-03
Oregon Health Sciences University
Substituted amidines having high binding to the sigma receptor and the use thereof

Families Citing this family (21)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

EP0633256A1
(en)

*

1988-12-13
1995-01-11
Beecham Group Plc
Benzopyran and related compounds

FR2645021A1
(en)

*

1989-03-30
1990-10-05
Sanofi Sa

USE OF A POTASSIC AGONIST IN THE TREATMENT OF GLAUCOMA

FR2653662B1
(en)

*

1989-10-31
1994-05-13
Rhone Poulenc Sante

APPLICATION OF N-METHYL (PYRIDYL-3) -2 TETRAHYDROTHIOPYRANNE-CARBOTHIOAMIDE-2-OXIDE-1 TO THE PREPARATION OF MEDICINES FOR THE TREATMENT OF CORONARY INSUFFICIENCY.

FR2657872B2
(en)

*

1989-11-06
1992-06-12
Sanofi Sa

AMIDINO-4 CHROMAN DERIVATIVE, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.

TW224941B
(en)

*

1989-11-08
1994-06-11
Yamanouchi Pharma Co Ltd

US5643921A
(en)

*

1990-09-26
1997-07-01
E.R. Squibb & Sons, Inc.
Cardiopulmonary bypass and organ transplant using a potassium channel activator

GB9124754D0
(en)

*

1991-11-21
1992-01-15
Smithkline Beecham Plc
Pharmaceuticals

GB9807779D0
(en)

1998-04-09
1998-06-10
Ciba Geigy Ag
Organic compounds

US6417207B1
(en)

1999-05-12
2002-07-09
Nitromed, Inc.
Nitrosated and nitrosylated potassium channel activators, compositions and methods of use

US20050089559A1
(en)

*

2003-10-23
2005-04-28
Istvan Szelenyi
Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains

JP2008523145A
(en)

*

2004-12-13
2008-07-03
イーライ リリー アンド カンパニー

Spiro derivatives as lipoxygenase inhibitors

US7960436B2
(en)

*

2006-06-05
2011-06-14
Valeant Pharmaceuticals International
Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators

US20080045534A1
(en)

*

2006-08-18
2008-02-21
Valeant Pharmaceuticals North America
Derivatives of 1,3-diamino benzene as potassium channel modulators

BRPI0716715B1
(en)

*

2006-08-23
2021-07-06
Xenon Pharmaceuticals, Inc

4-(N-AZACICLOALKYL) DERIVATIVES AS POTASSIUM CHANNEL MODULATORS, THEIR USES, PRODUCT, COMPOSITION, TABLET AND CAPSULE

US8993593B2
(en)

*

2006-08-23
2015-03-31
Valeant Pharmaceuticals International
N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators

US8722929B2
(en)

*

2006-10-10
2014-05-13
Valeant Pharmaceuticals International
N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators

CA2670966A1
(en)

*

2006-11-28
2008-06-05
Valeant Pharmaceuticals International
1,4 diamino bicyclic retigabine analogues as potassium channel modulators

US20080207073A1
(en)

*

2007-02-22
2008-08-28
David Michael Jones
Coated multi-purpose fabric

US8367684B2
(en)

*

2007-06-13
2013-02-05
Valeant Pharmaceuticals International
Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators

US8563566B2
(en)

2007-08-01
2013-10-22
Valeant Pharmaceuticals International
Naphthyridine derivatives as potassium channel modulators

US7786146B2
(en)

*

2007-08-13
2010-08-31
Valeant Pharmaceuticals International
Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators

Family Cites Families (25)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB1489879A
(en)

*

1974-12-20
1977-10-26
Leo Pharm Prod Ltd
N’-cyano-n’-3-pyridylguanidines

ATE23718T1
(en)

*

1981-09-25
1986-12-15
Beecham Group Plc

BENZOPYRAN COMPOUNDS WITH PHARMACEUTICAL ACTIVITY.

DE3364145D1
(en)

*

1982-04-08
1986-07-24
Beecham Group Plc

ANTI-HYPERTENSIVE BENZOPYRANOLS

EP0093535B1
(en)

*

1982-04-28
1986-12-30
Beecham Group Plc
Novel chromenes and chromans

EP0095316B1
(en)

*

1982-05-21
1986-12-03
Beecham Group Plc
Pharmaceutically active aminobenzopyrans

EP0107423B1
(en)

*

1982-10-19
1986-07-23
Beecham Group Plc
Novel chromans and chromenes

GB8308063D0
(en)

*

1983-03-24
1983-05-05
Beecham Group Plc
Active compounds

GB8308064D0
(en)

*

1983-03-24
1983-05-05
Beecham Group Plc
Active compounds

DE3479726D1
(en)

*

1983-05-18
1989-10-19
Beecham Group Plc

BENZOPYRAN DERIVATIVES.

DE3486354T2
(en)

*

1983-05-18
1995-03-30
Beecham Group Plc

Chromium and chromium derivatives.

GB8313679D0
(en)

*

1983-05-18
1983-06-22
Beecham Group Plc
Active compounds

EP0139992B1
(en)

*

1983-09-01
1988-12-28
Beecham Group Plc
Chromanol derivatives

EP0138134B1
(en)

*

1983-10-13
1989-04-19
Beecham Group Plc
Chroman derivatives

GB8419516D0
(en)

*

1984-07-31
1984-09-05
Beecham Group Plc
Treatment

GB8419515D0
(en)

*

1984-07-31
1984-09-05
Beecham Group Plc
Treatment

GB8513369D0
(en)

*

1985-05-28
1985-07-03
Beecham Group Plc
Treatment

EP0205292B1
(en)

*

1985-06-08
1991-11-06
Beecham Group Plc
Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them

GB8521857D0
(en)

*

1985-09-03
1985-10-09
Beecham Group Plc
Active compounds

PT84806B
(en)

*

1986-05-03
1989-12-29
Beecham Group Plc

PROCESS FOR THE PREPARATION OF BENZOPYRANES

GB8613786D0
(en)

*

1986-06-06
1986-07-09
Beecham Group Plc
Active compounds

GB8625185D0
(en)

*

1986-10-21
1986-11-26
Beecham Group Plc
Active compounds

ATE71535T1
(en)

*

1986-12-06
1992-02-15
Beecham Group Plc

PHARMACEUTICAL PREPARATIONS.

DE3726261A1
(en)

*

1986-12-23
1988-07-07
Merck Patent Gmbh

CHROME DERIVATIVES

EP0277611B1
(en)

*

1987-02-04
1993-06-16
Hoechst Aktiengesellschaft
Alkyl-substituted n-benzopyranyl lactames, process for their preparation, their use and pharmaceutical preparations on the basis of these compounds

DE3703227A1
(en)

*

1987-02-04
1988-08-18
Hoechst Ag

SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS

1988

1988-01-06
GB
GB888800199A
patent/GB8800199D0/en
active
Pending

1988-12-23
ES
ES88312287T
patent/ES2042776T3/en
not_active
Expired – Lifetime

1988-12-23
AT
AT88312287T
patent/ATE83375T1/en
active

1988-12-23
EP
EP88312287A
patent/EP0323745B1/en
not_active
Expired – Lifetime

1988-12-23
DE
DE8888312287T
patent/DE3876773T2/en
not_active
Revoked

1989

1989-01-04
CA
CA000587532A
patent/CA1317228C/en
not_active
Expired – Fee Related

1989-01-04
US
US07/293,209
patent/US5032591A/en
not_active
Expired – Fee Related

1989-01-04
AU
AU27696/89A
patent/AU614008B2/en
not_active
Ceased

1989-01-04
PT
PT89388A
patent/PT89388B/en
not_active
IP Right Cessation

1989-01-04
DK
DK002689A
patent/DK2689A/en
not_active
Application Discontinuation

1989-01-04
ZA
ZA8944A
patent/ZA8944B/en
unknown

1989-01-05
JP
JP64000827A
patent/JPH01224316A/en
active
Pending

1989-01-05
KR
KR1019890000134A
patent/KR890011591A/en
not_active
Application Discontinuation

1989-01-05
NZ
NZ227518A
patent/NZ227518A/en
unknown

1993

1993-01-21
GR
GR930400109T
patent/GR3006857T3/el
unknown

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU642961B2
(en)

*

1990-02-13
1993-11-04
Merck Patent Gesellschaft Mit Beschrankter Haftung
Pharmaceutical composition

US5552443A
(en)

*

1990-08-30
1996-09-03
Oregon Health Sciences University
Substituted amidines having high binding to the sigma receptor and the use thereof

Also Published As

Publication number
Publication date

EP0323745A3
(en)

1990-03-21

ES2042776T3
(en)

1993-12-16

KR890011591A
(en)

1989-08-21

DK2689A
(en)

1989-07-07

DE3876773T2
(en)

1993-04-29

EP0323745A2
(en)

1989-07-12

PT89388B
(en)

1993-09-30

DK2689D0
(en)

1989-01-04

EP0323745B1
(en)

1992-12-16

ATE83375T1
(en)

1993-01-15

NZ227518A
(en)

1991-08-27

ZA8944B
(en)

1990-09-26

JPH01224316A
(en)

1989-09-07

US5032591A
(en)

1991-07-16

DE3876773D1
(en)

1993-01-28

GB8800199D0
(en)

1988-02-10

CA1317228C
(en)

1993-05-04

PT89388A
(en)

1990-02-08

GR3006857T3
(en)

1993-06-30

AU614008B2
(en)

1991-08-15

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