AU3015289A – 2′-deoxy-5-fluorouridine derivatives
– Google Patents
AU3015289A – 2′-deoxy-5-fluorouridine derivatives
– Google Patents
2′-deoxy-5-fluorouridine derivatives
Info
Publication number
AU3015289A
AU3015289A
AU30152/89A
AU3015289A
AU3015289A
AU 3015289 A
AU3015289 A
AU 3015289A
AU 30152/89 A
AU30152/89 A
AU 30152/89A
AU 3015289 A
AU3015289 A
AU 3015289A
AU 3015289 A
AU3015289 A
AU 3015289A
Authority
AU
Australia
Prior art keywords
group
deoxy
chem
formula
acyl
Prior art date
1988-02-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU30152/89A
Other versions
AU610344B2
(en
Inventor
Tsutomu Kawai
Fumio Mori
Hitoshi Saito
Setsuo Takeda
Norio Unemi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1988-02-29
Filing date
1989-02-21
Publication date
1989-08-31
1989-02-21
Application filed by Taiho Pharmaceutical Co Ltd
filed
Critical
Taiho Pharmaceutical Co Ltd
1989-08-31
Publication of AU3015289A
publication
Critical
patent/AU3015289A/en
1991-05-16
Application granted
granted
Critical
1991-05-16
Publication of AU610344B2
publication
Critical
patent/AU610344B2/en
1993-02-18
Assigned to TAIHO PHARMACEUTICAL CO., LTD.
reassignment
TAIHO PHARMACEUTICAL CO., LTD.
Alteration of Name(s) in Register under S187
Assignors: KURARAY CO., LTD., TAIHO PHARMACEUTICAL CO., LTD.
2009-02-21
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
C07H19/06—Pyrimidine radicals
C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
C07H19/06—Pyrimidine radicals
C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Abstract
2 min -Deoxy-5-fluorouridine derivatives of the formula
AU30152/89A
1988-02-29
1989-02-21
2′-deoxy-5-fluorouridine derivatives
Ceased
AU610344B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
JP63-47864
1988-02-29
JP4786488
1988-02-29
Publications (2)
Publication Number
Publication Date
AU3015289A
true
AU3015289A
(en)
1989-08-31
AU610344B2
AU610344B2
(en)
1991-05-16
Family
ID=12787236
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU30152/89A
Ceased
AU610344B2
(en)
1988-02-29
1989-02-21
2′-deoxy-5-fluorouridine derivatives
Country Status (9)
Country
Link
US
(1)
US5032680A
(en)
EP
(1)
EP0331032B1
(en)
KR
(1)
KR890013009A
(en)
CN
(1)
CN1024349C
(en)
AT
(1)
ATE88714T1
(en)
AU
(1)
AU610344B2
(en)
CA
(1)
CA1313661C
(en)
DE
(1)
DE68906183T2
(en)
ES
(1)
ES2054899T3
(en)
Families Citing this family (26)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US5250673A
(en)
*
1983-05-23
1993-10-05
Taiho Pharmaceutical Company, Ltd.
2′-deoxy-5-substituted uridine derivatives
GB8823319D0
(en)
*
1988-10-05
1988-11-09
Nycomed As
Chemical compounds
DE4015715A1
(en)
*
1990-05-16
1991-11-21
Bayer Ag
NEW OLIGOPHOSPHATES WITH ANTIVIRAL EFFECT
US5627165A
(en)
*
1990-06-13
1997-05-06
Drug Innovation & Design, Inc.
Phosphorous prodrugs and therapeutic delivery systems using same
DK0533833T3
(en)
*
1990-06-13
1996-04-22
Arnold Glazier
Phosphorus prodrugs
US5272152A
(en)
*
1990-07-02
1993-12-21
E. R. Squibb & Sons, Inc.
Purinyl and pyrimidinyl tetrahydrofurans
EP0481214B1
(en)
*
1990-09-14
1998-06-24
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic
Prodrugs of phosphonates
US5233031A
(en)
*
1991-09-23
1993-08-03
University Of Rochester
Phosphoramidate analogs of 2′-deoxyuridine
US5314893A
(en)
*
1993-01-25
1994-05-24
Bristol-Myers Squibb Co.
Antiviral tetrahydropyrans
JP2526414B2
(en)
*
1994-05-20
1996-08-21
工業技術院長
Anticancer drug ester compound and method for producing the same
US6232465B1
(en)
1994-09-02
2001-05-15
Andrew C. Hiatt
Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides
US5990300A
(en)
*
1994-09-02
1999-11-23
Andrew C. Hiatt
Enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides
US6214987B1
(en)
1994-09-02
2001-04-10
Andrew C. Hiatt
Compositions for enzyme catalyzed template-independent formation of phosphodiester bonds using protected nucleotides
US5808045A
(en)
*
1994-09-02
1998-09-15
Andrew C. Hiatt
Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides
US5872244A
(en)
*
1994-09-02
1999-02-16
Andrew C. Hiatt
3′ protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
US5763594A
(en)
*
1994-09-02
1998-06-09
Andrew C. Hiatt
3′ protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
US6319908B1
(en)
*
1996-07-03
2001-11-20
Inspire Pharmaceuticals, Inc.
Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof
TW593331B
(en)
*
1997-07-25
2004-06-21
Inspire Pharmaceuticals Inc
Method for large-scale production of di(uridine 5′)-tetraphosphate and salts thereof
US6872710B2
(en)
*
1997-07-25
2005-03-29
Inspire Pharmaceuticals, Inc.
Di(uridine 5′)-tetraphosphate and salts thereof
AU5107600A
(en)
*
1999-06-11
2001-01-02
Fuji Photo Film Co., Ltd.
Aryl phosphates
DE10313035A1
(en)
*
2003-03-24
2004-10-07
Resprotect Gmbh
Method to increase the apoptotic effect of cytostatics without increasing toxic side effects
CN101765369A
(en)
*
2007-03-19
2010-06-30
俄勒冈州由俄勒冈州立大学代表州高等教育委员会行使
Mannich base N-oxide drugs
WO2009042064A2
(en)
2007-09-21
2009-04-02
Nektar Therapeutics Al, Corporation
Oligomer-nucleoside phosphate conjugates
CN101440111B
(en)
*
2008-12-22
2011-06-22
西安交通大学
Anti-tumor compound and preparation thereof
CN104151360B
(en)
*
2013-05-14
2019-02-22
北京美倍他药物研究有限公司
Phosphoric acid/phosphonate derivative and its medical usage
CN110678473A
(en)
*
2017-04-25
2020-01-10
大原药品工业株式会社
5′ -dibenzyl monophosphate derivatives of nucleoside anticancer or antiviral drugs
Family Cites Families (12)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS5535057A
(en)
*
1978-09-05
1980-03-11
Funai Corp
2′-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it
JPS56115799A
(en)
*
1980-02-15
1981-09-11
Funai Corp
2′-deoxy-3′,5′-di-o-alkylcarbonyl-5-fluorouridine derivative, its preparation, and antitumor agnet containing the same
JPS57128699A
(en)
*
1981-02-03
1982-08-10
Tokyo Kinzoku Kogyo Kk
5-fluorouracil derivative and its medical composition
JPS5899499A
(en)
*
1981-12-09
1983-06-13
Teijin Ltd
5-fluoro-2′-deoxyuridine derivative and its preparation
JPS5970699A
(en)
*
1982-10-13
1984-04-21
Teijin Ltd
5-fluoro-2′-deoxyuridine derivative and its preparation
DE3263939D1
(en)
*
1981-12-09
1985-07-04
Teijin Ltd
5-fluoro-2′-deoxyuridine derivatives and a process for the preparation thereof
JPS5993096A
(en)
*
1982-11-19
1984-05-29
Teijin Ltd
5-fluoro-2′-deoxyuridine derivative and its preparation
US4684631A
(en)
*
1984-10-09
1987-08-04
Toyama Chemical Co., Ltd.
Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same
JPS6191196A
(en)
*
1984-10-09
1986-05-09
Toyama Chem Co Ltd
Novel 5-fluoro-2′-deoxyuridine 5′-phosphate derivative and its salt
JPS6191195A
(en)
*
1984-10-12
1986-05-09
Toyama Chem Co Ltd
Novel 5-fluoro-2′-deoxyuridine-5′-phosphate derivative and its salt
JPS61152694A
(en)
*
1984-12-27
1986-07-11
Toyama Chem Co Ltd
Novel 5-fluoro-2′-deoxyuridine-5′-phosphate derivative and its salt
JPS61236793A
(en)
*
1985-04-15
1986-10-22
Toyo Jozo Co Ltd
Novel phospholipid nucleoside derivative
1989
1989-02-21
AU
AU30152/89A
patent/AU610344B2/en
not_active
Ceased
1989-02-24
EP
EP89103261A
patent/EP0331032B1/en
not_active
Expired – Lifetime
1989-02-24
US
US07/314,924
patent/US5032680A/en
not_active
Expired – Fee Related
1989-02-24
ES
ES89103261T
patent/ES2054899T3/en
not_active
Expired – Lifetime
1989-02-24
AT
AT89103261T
patent/ATE88714T1/en
not_active
IP Right Cessation
1989-02-24
DE
DE8989103261T
patent/DE68906183T2/en
not_active
Expired – Fee Related
1989-02-27
CA
CA000592229A
patent/CA1313661C/en
not_active
Expired – Fee Related
1989-02-28
CN
CN89101035A
patent/CN1024349C/en
not_active
Expired – Fee Related
1989-02-28
KR
KR1019890002397A
patent/KR890013009A/en
not_active
Application Discontinuation
Also Published As
Publication number
Publication date
CN1045395A
(en)
1990-09-19
DE68906183T2
(en)
1993-09-02
CA1313661C
(en)
1993-02-16
AU610344B2
(en)
1991-05-16
US5032680A
(en)
1991-07-16
CN1024349C
(en)
1994-04-27
EP0331032A1
(en)
1989-09-06
EP0331032B1
(en)
1993-04-28
ES2054899T3
(en)
1994-08-16
KR890013009A
(en)
1989-09-20
DE68906183D1
(en)
1993-06-03
ATE88714T1
(en)
1993-05-15
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