AU2123797A – 2-thioxotetrahydropyrimidin-4-one derivatives
– Google Patents
AU2123797A – 2-thioxotetrahydropyrimidin-4-one derivatives
– Google Patents
2-thioxotetrahydropyrimidin-4-one derivatives
Info
Publication number
AU2123797A
AU2123797A
AU21237/97A
AU2123797A
AU2123797A
AU 2123797 A
AU2123797 A
AU 2123797A
AU 21237/97 A
AU21237/97 A
AU 21237/97A
AU 2123797 A
AU2123797 A
AU 2123797A
AU 2123797 A
AU2123797 A
AU 2123797A
Authority
AU
Australia
Prior art keywords
thioxotetrahydropyrimidin
derivatives
Prior art date
1996-03-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU21237/97A
Other versions
AU707732B2
(en
Inventor
Sie-Yearl Chai
Hassan Mahmoud Elokdah
Theodore Sylvester Sulkowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1996-03-07
Filing date
1997-02-12
Publication date
1997-09-22
1997-02-12
Application filed by American Home Products Corp
filed
Critical
American Home Products Corp
1997-09-22
Publication of AU2123797A
publication
Critical
patent/AU2123797A/en
1999-07-15
Application granted
granted
Critical
1999-07-15
Publication of AU707732B2
publication
Critical
patent/AU707732B2/en
2017-02-12
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/33—Heterocyclic compounds
A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
AU21237/97A
1996-03-07
1997-02-12
2-thioxotetrahydropyrimidin-4-one derivatives
Ceased
AU707732B2
(en)
Applications Claiming Priority (3)
Application Number
Priority Date
Filing Date
Title
US1299396P
1996-03-07
1996-03-07
US60/012993
1996-03-07
PCT/US1997/002281
WO1997032855A1
(en)
1996-03-07
1997-02-12
2-thioxotetrahydropyrimidin-4-one derivatives
Publications (2)
Publication Number
Publication Date
AU2123797A
true
AU2123797A
(en)
1997-09-22
AU707732B2
AU707732B2
(en)
1999-07-15
Family
ID=21757747
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU21237/97A
Ceased
AU707732B2
(en)
1996-03-07
1997-02-12
2-thioxotetrahydropyrimidin-4-one derivatives
Country Status (15)
Country
Link
US
(1)
US5807864A
(en)
EP
(1)
EP0885197A1
(en)
JP
(1)
JP2000507926A
(en)
KR
(1)
KR19990087582A
(en)
CN
(1)
CN1217715A
(en)
AR
(1)
AR005986A1
(en)
AU
(1)
AU707732B2
(en)
BR
(1)
BR9708310A
(en)
CA
(1)
CA2247933A1
(en)
HU
(1)
HU9901968A3
(en)
IL
(1)
IL125974A0
(en)
NZ
(1)
NZ332199A
(en)
TW
(1)
TW422840B
(en)
WO
(1)
WO1997032855A1
(en)
ZA
(1)
ZA971911B
(en)
Families Citing this family (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
WO1998021190A1
(en)
*
1996-11-14
1998-05-22
American Home Products Corporation
Substituted tetrahydro-1,3,5-triazin-2[1h]-thiones as anti-atherosclerotic agents
WO2002028845A1
(en)
*
2000-10-02
2002-04-11
Wyeth
3-thioxo-[1,2,4]-oxadiazinan-5-one and their use as anti-antherosclerotic agents
US20050096319A1
(en)
*
2003-02-21
2005-05-05
Balzarini Jan M.R.
Identification of compounds that inhibit replication of human immunodeficiency virus
CN102423314A
(en)
*
2011-11-26
2012-04-25
济南环肽医药科技有限公司
Medicine for treating immunological liver injury or immunological liver fibrosis
Family Cites Families (7)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS55108858A
(en)
*
1979-02-14
1980-08-21
Kyowa Hakko Kogyo Co Ltd
Novel dihydrouracil derivative and herbicide
JPS5939875A
(en)
*
1982-08-31
1984-03-05
Sagami Chem Res Center
Preparation of 5-trifluoromethyldihydrouracils
JPS60243017A
(en)
*
1984-05-16
1985-12-03
Kyowa Hakko Kogyo Co Ltd
Antispasmodic composition
JPH0651682B2
(en)
*
1986-09-05
1994-07-06
株式会社上野製薬応用研究所
Method for producing uracil derivative
US4927451A
(en)
*
1988-12-30
1990-05-22
Uniroyal Chemical Company, Inc.
3-aryldihydrouracils
DE4318550A1
(en)
*
1993-06-04
1994-12-08
Boehringer Mannheim Gmbh
Arylidene-4-oxo-2-thioxo-3-thiazolidinecarboxylic acids, process for their preparation and pharmaceutical compositions containing them
US5554607A
(en)
*
1995-11-28
1996-09-10
American Home Products Corporation
Use of 2-thioxo-imidazolin-4-one derivatives in the treatment of atherosclerosis
1997
1997-02-12
WO
PCT/US1997/002281
patent/WO1997032855A1/en
not_active
Application Discontinuation
1997-02-12
NZ
NZ332199A
patent/NZ332199A/en
unknown
1997-02-12
IL
IL12597497A
patent/IL125974A0/en
unknown
1997-02-12
EP
EP97906583A
patent/EP0885197A1/en
not_active
Withdrawn
1997-02-12
JP
JP9531771A
patent/JP2000507926A/en
active
Pending
1997-02-12
HU
HU9901968A
patent/HU9901968A3/en
unknown
1997-02-12
CA
CA002247933A
patent/CA2247933A1/en
not_active
Abandoned
1997-02-12
BR
BR9708310A
patent/BR9708310A/en
not_active
Application Discontinuation
1997-02-12
CN
CN97194335A
patent/CN1217715A/en
active
Pending
1997-02-12
KR
KR1019980707023A
patent/KR19990087582A/en
not_active
Application Discontinuation
1997-02-12
AU
AU21237/97A
patent/AU707732B2/en
not_active
Ceased
1997-02-20
TW
TW086102010A
patent/TW422840B/en
active
1997-02-24
AR
ARP970100745A
patent/AR005986A1/en
unknown
1997-02-27
US
US08/807,164
patent/US5807864A/en
not_active
Expired – Lifetime
1997-03-05
ZA
ZA971911A
patent/ZA971911B/en
unknown
Also Published As
Publication number
Publication date
KR19990087582A
(en)
1999-12-27
US5807864A
(en)
1998-09-15
NZ332199A
(en)
1999-03-29
JP2000507926A
(en)
2000-06-27
EP0885197A1
(en)
1998-12-23
TW422840B
(en)
2001-02-21
WO1997032855A1
(en)
1997-09-12
ZA971911B
(en)
1998-09-07
CA2247933A1
(en)
1997-09-12
IL125974A0
(en)
1999-04-11
BR9708310A
(en)
1999-08-03
HU9901968A2
(en)
1999-10-28
AU707732B2
(en)
1999-07-15
HU9901968A3
(en)
2000-01-28
CN1217715A
(en)
1999-05-26
AR005986A1
(en)
1999-07-21
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Legal Events
Date
Code
Title
Description
2002-09-12
MK14
Patent ceased section 143(a) (annual fees not paid) or expired