AU2913589A – Method to solubilize tissue plasminogen activator
– Google Patents
AU2913589A – Method to solubilize tissue plasminogen activator
– Google Patents
Method to solubilize tissue plasminogen activator
Info
Publication number
AU2913589A
AU2913589A
AU29135/89A
AU2913589A
AU2913589A
AU 2913589 A
AU2913589 A
AU 2913589A
AU 29135/89 A
AU29135/89 A
AU 29135/89A
AU 2913589 A
AU2913589 A
AU 2913589A
AU 2913589 A
AU2913589 A
AU 2913589A
Authority
AU
Australia
Prior art keywords
plasminogen activator
tissue plasminogen
solubilize
solubilize tissue
activator
Prior art date
1987-12-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU29135/89A
Inventor
Stephen A. Duffy
Christopher P. Prior
Randal W. Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invitron Corp
Original Assignee
Invitron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1987-12-10
Filing date
1988-12-09
Publication date
1989-07-05
1988-12-09
Application filed by Invitron Corp
filed
Critical
Invitron Corp
1989-07-05
Publication of AU2913589A
publication
Critical
patent/AU2913589A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
C12N9/14—Hydrolases (3)
C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
C12N9/6424—Serine endopeptidases (3.4.21)
C12N9/6456—Plasminogen activators
C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
A61K47/12—Carboxylic acids; Salts or anhydrides thereof
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/0012—Galenical forms characterised by the site of application
A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
B—PERFORMING OPERATIONS; TRANSPORTING
B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
B01D—SEPARATION
B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
B01D15/08—Selective adsorption, e.g. chromatography
B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12Y—ENZYMES
C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
C12Y304/21—Serine endopeptidases (3.4.21)
C12Y304/21069—Protein C activated (3.4.21.69)
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K38/00—Medicinal preparations containing peptides
B—PERFORMING OPERATIONS; TRANSPORTING
B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
B01D—SEPARATION
B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
B01D15/08—Selective adsorption, e.g. chromatography
B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
AU29135/89A
1987-12-10
1988-12-09
Method to solubilize tissue plasminogen activator
Abandoned
AU2913589A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
US130901
1987-12-10
US07/130,901
US4898826A
(en)
1987-12-10
1987-12-10
Method to solubilize tissue plasminogen activator
Publications (1)
Publication Number
Publication Date
AU2913589A
true
AU2913589A
(en)
1989-07-05
Family
ID=22446886
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU29135/89A
Abandoned
AU2913589A
(en)
1987-12-10
1988-12-09
Method to solubilize tissue plasminogen activator
Country Status (3)
Country
Link
US
(1)
US4898826A
(en)
AU
(1)
AU2913589A
(en)
WO
(1)
WO1989005347A1
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU625307B2
(en)
*
1989-12-20
1992-07-09
Boehringer Mannheim Gmbh
Stabilization of k2p pro
AU625831B2
(en)
*
1989-12-20
1992-07-16
Boehringer Mannheim Gmbh
Solubilization of t-pa
Families Citing this family (14)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JP2708749B2
(en)
*
1987-08-10
1998-02-04
エーザイ株式会社
Injectable composition containing modified tPA
US4980165A
(en)
*
1989-01-27
1990-12-25
Genetics Institute, Inc.
Pharmaceutical formulations of plasminogen activator proteins
US5676947A
(en)
*
1989-02-07
1997-10-14
Boehringer Manneheim Gmbh
Method for treating thromboembolic conditions using thrombolytically active proteins
JP2520975B2
(en)
*
1989-09-21
1996-07-31
三井東圧化学株式会社
Thrombolytic agent containing tissue plasminogen activator or its derivative
IT1240314B
(en)
*
1989-09-28
1993-12-07
Immunobiology Research Institutes, Inc.
STABILIZED AQUEOUS FORMULATIONS OF SMALL PEPTIDES.
US5366730A
(en)
*
1989-12-20
1994-11-22
Boehringer Mannheim Gmbh
Stabilized compositions having human tissue type plasminogen activator enzymatic activity
ATE193301T1
(en)
*
1993-03-09
2000-06-15
Genzyme Corp
METHOD FOR ISOLATION OF PROTEINS FROM MILK
US5776498A
(en)
*
1995-11-06
1998-07-07
Nutrition 21
Magnesium taurate as an adjuvant to rapid thrombolytic therapy
DE69719265T2
(en)
*
1996-09-06
2003-12-04
Chemo Sero Therapeut Res Inst
Medicinal composition containing tissue plasminogen activator and nicotinamide
US20060019234A1
(en)
*
2004-07-22
2006-01-26
Shanbrom Technologies, Llc
Modern blood banking employing improved cell preservation composition
CN100337684C
(en)
*
2005-05-11
2007-09-19
北京双鹭药业股份有限公司
Thymic pentapeptide aqua prepn and its prepn process and application
WO2007149343A2
(en)
*
2006-06-16
2007-12-27
The Board Of Trustees Of The Leland Stanford Junior University
Proteases for treatment of venomous bites
GB0704488D0
(en)
*
2007-03-08
2007-04-18
Univ Nottingham
Platelet viability kit
US20090130714A1
(en)
*
2007-09-24
2009-05-21
Reliance Life Sciences Pvt.Ltd.
Process for purifying recombinanat tissue plasminogen activator (TPA)
Family Cites Families (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0156169B1
(en)
*
1984-02-29
1991-12-18
Asahi Kasei Kogyo Kabushiki Kaisha
An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method
JPH0672105B2
(en)
*
1985-10-02
1994-09-14
持田製薬株式会社
Thrombolytic agent and manufacturing method thereof
US4777043A
(en)
*
1985-12-17
1988-10-11
Genentech, Inc.
Stabilized human tissue plasminogen activator compositions
US4898825A
(en)
*
1986-05-07
1990-02-06
Mitsui Toatsu Chemicals, Incorporated
Methods for purification of single-chain and double-chain tissue plasminogen activator
1987
1987-12-10
US
US07/130,901
patent/US4898826A/en
not_active
Expired – Fee Related
1988
1988-12-09
WO
PCT/US1988/004402
patent/WO1989005347A1/en
unknown
1988-12-09
AU
AU29135/89A
patent/AU2913589A/en
not_active
Abandoned
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU625307B2
(en)
*
1989-12-20
1992-07-09
Boehringer Mannheim Gmbh
Stabilization of k2p pro
AU625831B2
(en)
*
1989-12-20
1992-07-16
Boehringer Mannheim Gmbh
Solubilization of t-pa
Also Published As
Publication number
Publication date
US4898826A
(en)
1990-02-06
WO1989005347A1
(en)
1989-06-15
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None