AU3016189A – Antibody-therapeutic agent conjugate intermediates
– Google Patents
AU3016189A – Antibody-therapeutic agent conjugate intermediates
– Google Patents
Antibody-therapeutic agent conjugate intermediates
Info
Publication number
AU3016189A
AU3016189A
AU30161/89A
AU3016189A
AU3016189A
AU 3016189 A
AU3016189 A
AU 3016189A
AU 30161/89 A
AU30161/89 A
AU 30161/89A
AU 3016189 A
AU3016189 A
AU 3016189A
AU 3016189 A
AU3016189 A
AU 3016189A
Authority
AU
Australia
Prior art keywords
antibody
therapeutic agent
agent conjugate
conjugate intermediates
intermediates
Prior art date
1984-09-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU30161/89A
Inventor
Vernon Leon Alvarez
Daniel James Coughlin
John Walter Frank Goers
Hurley Dalton King
Chyi Lee
Thomas Joseph Mckearn
John Dennis Rodwell
Richard Charles Siegel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytogen Corp
Original Assignee
Cytogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1984-09-13
Filing date
1989-02-21
Publication date
1989-07-13
1984-09-13
Priority claimed from US06/650,375
external-priority
patent/US4867973A/en
1989-02-21
Application filed by Cytogen Corp
filed
Critical
Cytogen Corp
1989-07-13
Publication of AU3016189A
publication
Critical
patent/AU3016189A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
A61K51/04—Organic compounds
A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
A61K51/04—Organic compounds
A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K2121/00—Preparations for use in therapy
AU30161/89A
1984-09-13
1989-02-21
Antibody-therapeutic agent conjugate intermediates
Abandoned
AU3016189A
(en)
Applications Claiming Priority (4)
Application Number
Priority Date
Filing Date
Title
US65075484A
1984-09-13
1984-09-13
US650375
1984-09-13
US650754
1984-09-13
US06/650,375
US4867973A
(en)
1984-08-31
1984-09-13
Antibody-therapeutic agent conjugates
Related Parent Applications (1)
Application Number
Title
Priority Date
Filing Date
AU48071/85A
Division
AU583854B2
(en)
1984-09-13
1985-09-10
Antibody therapeutic agent conjugates
Publications (1)
Publication Number
Publication Date
AU3016189A
true
AU3016189A
(en)
1989-07-13
Family
ID=27095841
Family Applications (2)
Application Number
Title
Priority Date
Filing Date
AU48071/85A
Ceased
AU583854B2
(en)
1984-09-13
1985-09-10
Antibody therapeutic agent conjugates
AU30161/89A
Abandoned
AU3016189A
(en)
1984-09-13
1989-02-21
Antibody-therapeutic agent conjugate intermediates
Family Applications Before (1)
Application Number
Title
Priority Date
Filing Date
AU48071/85A
Ceased
AU583854B2
(en)
1984-09-13
1985-09-10
Antibody therapeutic agent conjugates
Country Status (7)
Country
Link
EP
(1)
EP0175617B1
(en)
AU
(2)
AU583854B2
(en)
CA
(1)
CA1326834C
(en)
DE
(1)
DE3584559D1
(en)
DK
(1)
DK218386A
(en)
GR
(1)
GR852217B
(en)
WO
(1)
WO1986001720A1
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU655942B2
(en)
*
1990-10-05
1995-01-19
Queen’s University At Kingston
Porphyrin derivatives
Families Citing this family (55)
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Publication date
Assignee
Title
US5140104A
(en)
*
1982-03-09
1992-08-18
Cytogen Corporation
Amine derivatives of folic acid analogs
US4831122A
(en)
*
1986-01-09
1989-05-16
Regents Of The University Of Minnesota
Radioimmunotoxins
CA1330378C
(en)
*
1986-05-08
1994-06-21
Daniel J. Coughlin
Amine derivatives of folic acid analogs
US4801688A
(en)
*
1986-05-27
1989-01-31
Eli Lilly And Company
Hydrazone immunoglobulin conjugates
GB8628398D0
(en)
*
1986-11-27
1986-12-31
Central Blood Lab Authority
Pharmaceutically-active conjugates
US4835258A
(en)
*
1986-12-24
1989-05-30
Northwestsern University
Conjugation of aromatic amines or nitro-containing compounds with proteins or polypeptides by photoirradiation of the azide derivatives with ultraviolet light in order to produce antibodies against the haptens
EP0298101A1
(en)
*
1987-01-15
1989-01-11
Celltech Limited
Thiol-reactive cross-linking reagents
US4883790A
(en)
*
1987-01-20
1989-11-28
University Of British Columbia
Wavelength-specific cytotoxic agents
US5283255A
(en)
*
1987-01-20
1994-02-01
The University Of British Columbia
Wavelength-specific cytotoxic agents
US4920143A
(en)
*
1987-04-23
1990-04-24
University Of British Columbia
Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US5171749A
(en)
*
1987-01-20
1992-12-15
University Of British Columbia
Wavelength-specific cytotoxic agents
US5095030A
(en)
*
1987-01-20
1992-03-10
University Of British Columbia
Wavelength-specific cytotoxic agents
FR2610198B1
(en)
*
1987-02-03
1990-06-15
Ire Celltarg Sa
IMMUNOGLOBULIN-BOUND VINCA ALKALOID HYDRAZIDE CONJUGATES, METHOD OF PREPARATION, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
FR2611141B1
(en)
*
1987-02-20
1991-02-01
Int Rech Cancer Centre
ASSEMBLY OR KIT FOR USE AS AN AGENT FOR THE SELECTIVE DESTRUCTION OF TRANSFORMED OR TUMOR CELLS
EP0282057A3
(en)
*
1987-03-11
1990-03-07
The Board Of Regents Of The University Of Michigan
Chemo-radio-immuno-conjugates
US4937183A
(en)
*
1988-02-03
1990-06-26
Cytogen Corporation
Method for the preparation of antibody-fragment conjugates
US5047227A
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*
1988-02-08
1991-09-10
Cytogen Corporation
Novel and improved antibodies for site specific attachment of compounds
EP0336383A3
(en)
*
1988-04-07
1990-08-16
Takeda Chemical Industries, Ltd.
Novel recombinant human lymphotoxin
USRE39094E1
(en)
1988-07-20
2006-05-09
Health Research, Inc.
Pyropheophorbides and their use in photodynamic therapy
USRE38994E1
(en)
1988-07-20
2006-02-28
Health Research, Inc.
Pyropheophorbides conjugates and their use in photodynamic therapy
DE3827940A1
(en)
*
1988-08-13
1990-03-01
Schering Ag
13,17-PROPIONIC ACID AND PROPIONIC ACID DERIVATIVE SUBSTITUTED PORPHYRINE COMPLEX COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THEM
EP0434765B1
(en)
*
1988-09-30
1995-11-08
Neorx Corporation
Targeting substance-diagnostic/therapeutic agent conjugates having schiff base linkages
US5066789A
(en)
*
1988-09-30
1991-11-19
Neorx Corporation
Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
GR890100827A
(en)
*
1988-12-21
1991-03-15
Abbott Lab
Derivatives of tetrapeptides as cck agonists.
US5270302A
(en)
*
1988-12-21
1993-12-14
Abbott Laboratories
Derivatives of tetrapeptides as CCK agonists
US5308608A
(en)
*
1989-06-07
1994-05-03
University Of British Columbia
Photosensitizing Diels-Alder porphyrin derivatives
CA2056431A1
(en)
*
1989-06-07
1990-12-08
David Dolphin
Photosensitizing diels-alder porphyrin derivatives
AU5732290A
(en)
*
1989-06-30
1991-01-17
Brunswick Corporation
Antibody-oxidase conjugates with non-systemic substrates
WO1991009134A1
(en)
*
1989-12-15
1991-06-27
Takeda Chemical Industries, Ltd.
Biospecific antibody to cancer cell and enzyme with prodrug-activating characteristics
JPH05508394A
(en)
*
1990-04-25
1993-11-25
ファルマシア・アンド・アップジョン・カンパニー
New CC-1065 analog
US5272253A
(en)
*
1991-07-01
1993-12-21
Eli Lilly And Company
Cluster conjugates of drugs with antibodies
GR1001459B
(en)
*
1992-10-08
1993-12-30
Lilly Co Eli
Optically active insoindoline derivatives, their production and use.
WO1997033620A2
(en)
*
1996-03-15
1997-09-18
Pulsion Verw. Gmbh & Co. Medical Systems Kg
Compounds for treating tumours
US6493570B1
(en)
*
1998-11-02
2002-12-10
Photogen, Inc.
Method for improved imaging and photodynamic therapy
US7390668B2
(en)
*
1996-10-30
2008-06-24
Provectus Pharmatech, Inc.
Intracorporeal medicaments for photodynamic treatment of disease
ITRM960808A1
(en)
*
1996-11-26
1998-05-26
Rossolini Gianmaria
IMMUNOCONUGHTS INCLUDING HUMAN MONOCLONAL ANTIBODIES OR FRAGMENTS OF THEM FOR IN VIVO DIAGNOSIS AND THERAPY
DE19717904A1
(en)
*
1997-04-23
1998-10-29
Diagnostikforschung Inst
Acid-labile and enzymatically cleavable dye constructs for diagnostics with near infrared light and for therapy
US7648695B2
(en)
1998-08-06
2010-01-19
Provectus Pharmatech, Inc.
Medicaments for chemotherapeutic treatment of disease
US8557298B2
(en)
1998-08-06
2013-10-15
Provectus Pharmatech, Inc.
Medicaments for chemotherapeutic treatment of disease
WO2000041726A2
(en)
*
1999-01-15
2000-07-20
Light Sciences Corporation
Noninvasive vascular therapy
US6602274B1
(en)
*
1999-01-15
2003-08-05
Light Sciences Corporation
Targeted transcutaneous cancer therapy
EP2020242B1
(en)
*
1999-08-13
2011-10-19
Provectus Pharmatech, Inc.
Improved Topical Medicaments and Methods for Photodynamic Treatment of Disease
JP2007501811A
(en)
*
2003-08-08
2007-02-01
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト
Use of galactose oxidase for selective chemical conjugation of a retarder molecule to a protein of therapeutic interest.
US20070258993A1
(en)
*
2003-11-12
2007-11-08
The Austin Research Institute
Dna-Carrier Conjugate
US7541330B2
(en)
2004-06-15
2009-06-02
Kosan Biosciences Incorporated
Conjugates with reduced adverse systemic effects
EP2380909A1
(en)
2010-04-26
2011-10-26
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
PTK-7 protein involved in breast cancer
US9850296B2
(en)
2010-08-10
2017-12-26
Ecole Polytechnique Federale De Lausanne (Epfl)
Erythrocyte-binding therapeutics
CA2807942C
(en)
2010-08-10
2021-07-27
Ecole Polytechnique Federale De Lausanne
Erythrocyte-binding therapeutics
US9517257B2
(en)
2010-08-10
2016-12-13
Ecole Polytechnique Federale De Lausanne (Epfl)
Erythrocyte-binding therapeutics
WO2015140648A2
(en)
2014-02-21
2015-09-24
Ecole Polytecnique Federale De Lausanne (Epfl) Epfl-Tto
Glycotargeting therapeutics
US10046056B2
(en)
2014-02-21
2018-08-14
École Polytechnique Fédérale De Lausanne (Epfl)
Glycotargeting therapeutics
US10946079B2
(en)
2014-02-21
2021-03-16
Ecole Polytechnique Federale De Lausanne
Glycotargeting therapeutics
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2014-02-21
2021-03-23
École Polytechnique Fédérale De Lausanne (Epfl)
Glycotargeting therapeutics
WO2018232176A1
(en)
2017-06-16
2018-12-20
The University Of Chicago
Compositions and methods for inducing immune tolerance
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*
2018-01-05
2019-07-11
Gencyte Therapeutics, Inc.
Precision molecular adaptor system for car-t immunotherapy
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Assignee
Title
US3970521A
(en)
*
1974-08-07
1976-07-20
Exxon Research And Engineering Company
Immobilized glycoenzymes
CA1083508A
(en)
*
1975-11-13
1980-08-12
Jacques Grange
Supports having lateral chains, process for obtaining such supports, process for the fixation of organic compounds comprising a glucidic residue on said supports, products and reactives from said chimical fixation
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(en)
*
1976-05-20
1977-11-26
Hidetoshi Tsuchida
Highhpolymeric complex of covalent type
CA1203164A
(en)
*
1982-03-09
1986-04-15
Thomas J. Mckearn
Antibody conjugates
1985
1985-09-10
WO
PCT/US1985/001700
patent/WO1986001720A1/en
unknown
1985-09-10
AU
AU48071/85A
patent/AU583854B2/en
not_active
Ceased
1985-09-11
CA
CA000490424A
patent/CA1326834C/en
not_active
Expired – Lifetime
1985-09-12
GR
GR852217A
patent/GR852217B/el
unknown
1985-09-13
DE
DE8585401776T
patent/DE3584559D1/en
not_active
Expired – Fee Related
1985-09-13
EP
EP85401776A
patent/EP0175617B1/en
not_active
Expired – Lifetime
1986
1986-05-12
DK
DK218386A
patent/DK218386A/en
not_active
Application Discontinuation
1989
1989-02-21
AU
AU30161/89A
patent/AU3016189A/en
not_active
Abandoned
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU655942B2
(en)
*
1990-10-05
1995-01-19
Queen’s University At Kingston
Porphyrin derivatives
Also Published As
Publication number
Publication date
DK218386D0
(en)
1986-05-12
AU583854B2
(en)
1989-05-11
AU4807185A
(en)
1986-04-08
EP0175617A2
(en)
1986-03-26
EP0175617B1
(en)
1991-10-30
WO1986001720A1
(en)
1986-03-27
CA1326834C
(en)
1994-02-08
DE3584559D1
(en)
1991-12-05
GR852217B
(en)
1986-01-14
EP0175617A3
(en)
1988-06-15
DK218386A
(en)
1986-07-11
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