AU4061085A – Composition useful for obtaining vaccines containing particles carrying the surface antigene of hepatitis b virus and the receptor of polymerized human serum albumin, animal cells capable of producing such particles and method for the obtention thereof
– Google Patents
AU4061085A – Composition useful for obtaining vaccines containing particles carrying the surface antigene of hepatitis b virus and the receptor of polymerized human serum albumin, animal cells capable of producing such particles and method for the obtention thereof
– Google Patents
Composition useful for obtaining vaccines containing particles carrying the surface antigene of hepatitis b virus and the receptor of polymerized human serum albumin, animal cells capable of producing such particles and method for the obtention thereof
Info
Publication number
AU4061085A
AU4061085A
AU40610/85A
AU4061085A
AU4061085A
AU 4061085 A
AU4061085 A
AU 4061085A
AU 40610/85 A
AU40610/85 A
AU 40610/85A
AU 4061085 A
AU4061085 A
AU 4061085A
AU 4061085 A
AU4061085 A
AU 4061085A
Authority
AU
Australia
Prior art keywords
particles
hepatitis
receptor
antigene
obtention
Prior art date
1984-03-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU40610/85A
Other versions
AU598181B2
(en
Inventor
Yves Malpiece
Marie-Louise Michel
Elaine Sobczak
Rolf E. Streeck
Pierre Tiollais
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GROUPEMENT DE GENIE GENETIQUE
Centre National de la Recherche Scientifique CNRS
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
GROUPEMENT DE GENIE GENETIQUE
Centre National de la Recherche Scientifique CNRS
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1984-03-07
Filing date
1985-03-07
Publication date
1985-09-24
1985-03-07
Application filed by GROUPEMENT DE GENIE GENETIQUE, Centre National de la Recherche Scientifique CNRS, Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM
filed
Critical
GROUPEMENT DE GENIE GENETIQUE
1985-09-24
Publication of AU4061085A
publication
Critical
patent/AU4061085A/en
1990-06-21
Application granted
granted
Critical
1990-06-21
Publication of AU598181B2
publication
Critical
patent/AU598181B2/en
2005-03-07
Anticipated expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K39/00—Medicinal preparations containing antigens or antibodies
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
C12N2730/00—Reverse transcribing DNA viruses
C12N2730/00011—Details
C12N2730/10011—Hepadnaviridae
C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Abstract
Compsn. for vaccine prodn. comprises (or contains) polypeptide particles which are practically spherical (at least those having immunogenic and immunological characteristics of hepatitis B surface antigen) with diam. 18-25 (pref. 20-22)nm and density allowing sepn. in a density region 1.2-1.22 g/ml in a CsCl gradient. The compsn. is totally free of Dane particles and of envelope antigen (including core antigen), and the particles also contain a receptor for polymerised human albumin. Also new are (1) vectors for transforming eucaryotic cells contg. a DNA sequence coding for the S and pre-S regions of HBV under direct control of an exogenous promoter which is very efficient for expression in the intended animal host cells and (2) animal cell lines transformed with these vectors.
AU40610/85A
1984-03-07
1985-03-07
Composition useful for obtaining vaccines containing particles carrying the surface antigene of hepatitis b virus and the receptor of polymerized human serum albumin, animal cells capable of producing such particles and method for the obtention thereof
Expired
AU598181B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
FR8403564
1984-03-07
FR8403564A
FR2560890B1
(en)
1984-03-07
1984-03-07
COMPOSITION USEFUL FOR THE MANUFACTURE OF VACCINES CONTAINING PARTICLES CARRYING THE SURFACE ANTIGEN OF HEPATITIS B VIRUS AND THE POLYMERIZED HUMAN SERUM ALBUMIN RECEPTOR, ANIMAL CELLS CAPABLE OF PRODUCING SUCH PARTICLES
Publications (2)
Publication Number
Publication Date
AU4061085A
true
AU4061085A
(en)
1985-09-24
AU598181B2
AU598181B2
(en)
1990-06-21
Family
ID=9301807
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU40610/85A
Expired
AU598181B2
(en)
1984-03-07
1985-03-07
Composition useful for obtaining vaccines containing particles carrying the surface antigene of hepatitis b virus and the receptor of polymerized human serum albumin, animal cells capable of producing such particles and method for the obtention thereof
Country Status (10)
Country
Link
EP
(2)
EP0732104A1
(en)
JP
(1)
JPH08839B2
(en)
KR
(1)
KR930003609B1
(en)
AT
(1)
ATE141168T1
(en)
AU
(1)
AU598181B2
(en)
CA
(1)
CA1262532A
(en)
DE
(1)
DE3588117T2
(en)
FR
(1)
FR2560890B1
(en)
SU
(1)
SU1625332A3
(en)
WO
(1)
WO1985003876A1
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU619753B2
(en)
*
1987-06-22
1992-02-06
Medeva Holdings B.V.
Hepatitis b surface antigen vaccine
Families Citing this family (8)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
IL79740A0
(en)
*
1986-08-17
1986-11-30
Yeda Res & Dev
Hepatitis vaccine
FR2608052B1
(en)
*
1986-12-10
1990-04-13
Pasteur Vaccins
PROCESS FOR THE PREPARATION OF A HEPATITIS B VACCINE AND VACCINE OBTAINED
JP2758184B2
(en)
1987-06-22
1998-05-28
メデバ ホールディングス ベスローテン ベノートスハップ
Hepatitis B surface antigen vaccine
EP0304578B1
(en)
*
1987-06-22
2001-10-24
Medeva Holdings Bv
Peptide comprising hepatitis B surface antigen
EP0328123A1
(en)
*
1988-02-09
1989-08-16
Eugene Tech International, Inc.
Heterogeneous, pre-S rich hepatitis B surface antigen
EP0491077A1
(en)
*
1990-12-19
1992-06-24
Medeva Holdings B.V.
A composition used as a therapeutic agent against chronic viral hepatic diseases
FR2711670B1
(en)
1993-10-22
1996-01-12
Pasteur Institut
Nucleotide vector, composition containing it and vaccine for immunization against hepatitis.
JP4085231B2
(en)
*
2000-02-28
2008-05-14
株式会社ビークル
Protein hollow nanoparticles, substance carrier using the same, and method for introducing substance into cells
Family Cites Families (11)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4113712A
(en)
*
1976-03-08
1978-09-12
The Green Cross Corporation
HBsAG Particle composed of single polypeptide subunits and the preparation procedure
CA1100037A
(en)
*
1977-03-11
1981-04-28
Chung-Mei Ling
Hb.sub.c ag coated on solid phase
NO794196L
(en)
*
1978-12-22
1980-06-24
Biogen Nv
PROCEDURE FOR PREPARING A RECOMBINED DNA MOLECULE
JPS5610119A
(en)
*
1979-07-05
1981-02-02
Alpha Therapeutic Corp
Manufacture of b type hepatitis infection preventive vaccine
FR2480780B1
(en)
*
1980-04-22
1985-12-06
Pasteur Institut
PROCESS FOR THE TRANSFORMATION OF CELLS, ESPECIALLY EUKARYOTES, BY CIRCULAR DNA SUCH AS THAT OF HEPATITIS B VIRUS AND PREPARATIONS CONTAINING THE EXPRESSION PRODUCTS OF SAID DNA
EP0038765B1
(en)
*
1980-04-22
1987-09-02
Institut Pasteur
Vaccine against viral hepatitis b, method and transformed eucaryotic cells for the preparation of this vaccine
ZW18282A1
(en)
*
1981-08-31
1983-03-23
Genentech Inc
Preparation of polypeptides in vertebrate cell culture
JPS5936698A
(en)
*
1982-08-20
1984-02-28
Science & Tech Agency
Recombinant dna recombined with gene of virus of hepatitis b, transformed animal cell, and preparation of protein of virus of hepatitis b
US4847080A
(en)
*
1984-03-07
1989-07-11
New York Blood Center, Inc.
Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipide vesicle carriers
WO1985004103A1
(en)
*
1984-03-09
1985-09-26
Scripps Clinic And Research Foundation
Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
NL8401066A
(en)
*
1984-04-04
1985-11-01
Stichting Centraal Lab
PROCESS FOR PREPARING PREPARATIONS INCREASING HUMORAL AND CELLULAR IMMUNE ACTIVITY
1984
1984-03-07
FR
FR8403564A
patent/FR2560890B1/en
not_active
Expired
1985
1985-03-07
WO
PCT/FR1985/000044
patent/WO1985003876A1/en
unknown
1985-03-07
AU
AU40610/85A
patent/AU598181B2/en
not_active
Expired
1985-03-07
EP
EP95120494A
patent/EP0732104A1/en
not_active
Withdrawn
1985-03-07
DE
DE3588117T
patent/DE3588117T2/en
not_active
Expired – Lifetime
1985-03-07
JP
JP60501078A
patent/JPH08839B2/en
not_active
Expired – Lifetime
1985-03-07
CA
CA000475890A
patent/CA1262532A/en
not_active
Expired
1985-03-07
AT
AT85400444T
patent/ATE141168T1/en
not_active
IP Right Cessation
1985-03-07
EP
EP85400444A
patent/EP0156712B1/en
not_active
Expired – Lifetime
1985-11-06
SU
SU854011814A
patent/SU1625332A3/en
active
1985-11-06
KR
KR1019850700290A
patent/KR930003609B1/en
not_active
IP Right Cessation
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU619753B2
(en)
*
1987-06-22
1992-02-06
Medeva Holdings B.V.
Hepatitis b surface antigen vaccine
Also Published As
Publication number
Publication date
KR850700214A
(en)
1985-12-26
KR930003609B1
(en)
1993-05-08
EP0732104A1
(en)
1996-09-18
DE3588117T2
(en)
1997-03-20
FR2560890B1
(en)
1987-10-16
FR2560890A1
(en)
1985-09-13
ATE141168T1
(en)
1996-08-15
AU598181B2
(en)
1990-06-21
JPH08839B2
(en)
1996-01-10
JPS61500971A
(en)
1986-05-15
WO1985003876A1
(en)
1985-09-12
EP0156712B1
(en)
1996-08-14
CA1262532A
(en)
1989-10-31
SU1625332A3
(en)
1991-01-30
EP0156712A1
(en)
1985-10-02
DE3588117D1
(en)
1996-09-19
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