AU4061478A

AU4061478A – Azetidine derivatives
– Google Patents

AU4061478A – Azetidine derivatives
– Google Patents
Azetidine derivatives

Info

Publication number
AU4061478A

AU4061478A
AU40614/78A
AU4061478A
AU4061478A
AU 4061478 A
AU4061478 A
AU 4061478A
AU 40614/78 A
AU40614/78 A
AU 40614/78A
AU 4061478 A
AU4061478 A
AU 4061478A
AU 4061478 A
AU4061478 A
AU 4061478A
Authority
AU
Australia
Prior art keywords
azetidine derivatives
azetidine
derivatives
Prior art date
1977-10-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU40614/78A
Other versions

AU531084B2
(en

Inventor
DAVID BRUCE RANDOLPH JOHNSTON and SUSAN MARGARET SCHMITT BURTON GRANT CHRISTENSEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1977-10-19
Filing date
1978-10-11
Publication date
1980-04-17

1978-10-11
Application filed by Merck and Co Inc
filed
Critical
Merck and Co Inc

1980-04-17
Publication of AU4061478A
publication
Critical
patent/AU4061478A/en

1983-08-11
Application granted
granted
Critical

1983-08-11
Publication of AU531084B2
publication
Critical
patent/AU531084B2/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring

C07D477/26—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 4

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings

C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring

C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2

C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6

C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3

C07D477/20—Sulfur atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM

C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System

C07F7/02—Silicon compounds

C07F7/08—Compounds having one or more C—Si linkages

C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

AU40614/78A
1977-10-19
1978-10-11
Azetidine derivatives

Expired

AU531084B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US84337877A

1977-10-19
1977-10-19

USUS843378

1977-10-19

Related Child Applications (1)

Application Number
Title
Priority Date
Filing Date

AU15244/83A
Division

AU542222B2
(en)

1977-10-19
1983-05-31
Azetidine derivatives

Publications (2)

Publication Number
Publication Date

AU4061478A
true

AU4061478A
(en)

1980-04-17

AU531084B2

AU531084B2
(en)

1983-08-11

Family
ID=25289794
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU40614/78A
Expired

AU531084B2
(en)

1977-10-19
1978-10-11
Azetidine derivatives

Country Status (9)

Country
Link

EP
(1)

EP0001628B1
(en)

JP
(1)

JPS5466697A
(en)

AU
(1)

AU531084B2
(en)

DE
(1)

DE2862364D1
(en)

DK
(1)

DK464578A
(en)

ES
(1)

ES474288A1
(en)

IE
(1)

IE47958B1
(en)

IT
(1)

IT1109318B
(en)

ZA
(1)

ZA785858B
(en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU4061378A
(en)

*

1977-10-19
1980-04-17
Merck & Co., Inc.
1-azabicyclo (3.2.0) hept-2-enes

US4263314A
(en)

*

1978-01-19
1981-04-21
Beecham Group Limited
β-Lactam antibiotics, a process for their preparation and their use in pharmaceutical compositions

EP0008888B1
(en)

*

1978-08-23
1983-09-21
Beecham Group Plc
Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them

DE2961882D1
(en)

*

1978-08-25
1982-03-04
Beecham Group Plc
Beta-lactam anti-bacterials, compositions containing them and a process for their preparation

EP0010317B1
(en)

*

1978-10-24
1983-12-21
Merck & Co. Inc.
6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds

JPS5622787A
(en)

*

1979-07-27
1981-03-03
Sanraku Inc
Beta-lactam compound

DE2965394D1
(en)

*

1978-11-01
1983-06-16
Sanraku Ocean Co
Process for producing antibiotic beta-lactam compounds

JPS55136282A
(en)

*

1979-04-06
1980-10-23
Shionogi & Co Ltd
Novel antibiotic pa-31088-4

DK165280A
(en)

*

1979-04-19
1980-10-20
Merck & Co Inc

PROCEDURE FOR PREPARING 2- AND 6-SUBSTITUTED 1-CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACIDS AND INTERMEDIATES FOR USE IN THE PRESENTATION OF THE PROCEDURE

JPS5610165A
(en)

*

1979-07-05
1981-02-02
Sumitomo Chem Co Ltd
Novel beta-lactam compound and its production

DE3164021D1
(en)

*

1980-01-25
1984-07-19
Beecham Group Plc
Beta-lactam containing compounds, their preparation and use

US4409147A
(en)

*

1980-03-10
1983-10-11
Takeda Chemical Industries, Ltd.
Carbapenem compounds and their production

JPS56145271A
(en)

*

1980-04-11
1981-11-11
Dai Ichi Seiyaku Co Ltd
2-azetidinone derivative

JPS56161393A
(en)

*

1980-05-16
1981-12-11
Sanraku Inc
Beta-lactam compound

PT73791B
(en)

*

1980-10-17
1983-10-14
Merck & Co Inc
Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids

EP0050927B1
(en)

*

1980-10-25
1985-03-27
Beecham Group Plc
The preparation of beta-lactam antibiotics

US4361512A
(en)

*

1980-11-26
1982-11-30
Merck & Co., Inc.
2-Substituted thio-6-substituted-carbapen-2-em-3-carboxylic acids

WO1982001871A1
(en)

*

1980-12-03
1982-06-10
Ochiai Michihiko
Process for preparing a 1-sulfo-2-oxoazetidine derivative

EP0059554A3
(en)

*

1981-02-27
1982-10-20
Beecham Group Plc
Beta-lactam antibiotics, a process for their preparation and their use in pharmaceutical compositions

US4683301A
(en)

*

1982-04-08
1987-07-28
Bristol-Myers Company
Carbapenem antibiotics

CA1198440A
(en)

*

1982-04-08
1985-12-24
Choung U. Kim
Carbapenem antibiotics

US4710568A
(en)

*

1982-04-09
1987-12-01
Bristol-Myers Company
Carbapenem antibiotics

US4642341A
(en)

*

1982-04-09
1987-02-10
Bristol-Myers Company
Carbapenem antibiotics

EP0093915A1
(en)

*

1982-05-10
1983-11-16
Gruppo Lepetit S.P.A.
Novel beta-lactam derivatives

US4665170A
(en)

*

1982-06-18
1987-05-12
Bristol-Myers Company
Carbapenem antibiotics

US4536335A
(en)

*

1982-06-18
1985-08-20
Bristol-Myers Company
Carbapenem antibiotics

US4640799A
(en)

*

1982-06-18
1987-02-03
Bristol-Myers Company
Carbapenem antibiotics

US4746736A
(en)

*

1982-09-28
1988-05-24
Bristol-Myers Company
Carbapenem antibiotics

EP0105658A1
(en)

*

1982-09-28
1984-04-18
Beecham Group Plc
Beta-lactam compounds

US4732977A
(en)

*

1982-09-28
1988-03-22
Bristol Myers Company
Carbapenem antibiotics

US4665169A
(en)

*

1985-09-11
1987-05-12
Bristol-Myers Company
Carbapenem antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3950357A
(en)

*

1974-11-25
1976-04-13
Merck & Co., Inc.
Antibiotics

GB1570988A
(en)

*

1975-11-21
1980-07-09
Merck & Co Inc
Antibiotics of the thienamycin class

GB1593524A
(en)

*

1976-11-19
1981-07-15
Merck & Co Inc
1-carba-2-penem-3-carboxylic acids

NL7712093A
(en)

*

1976-11-19
1978-05-23
Merck & Co Inc

PROCESS FOR PREPARING ISOMERIC THIENAMYCINS.

DE2862198D1
(en)

*

1977-08-06
1983-04-14
Beecham Group Plc
Synthetic beta-lactam compounds, a process for their preparation and compositions containing them

AU4061378A
(en)

*

1977-10-19
1980-04-17
Merck & Co., Inc.
1-azabicyclo (3.2.0) hept-2-enes

1978

1978-10-11
AU
AU40614/78A
patent/AU531084B2/en
not_active
Expired

1978-10-16
EP
EP78101157A
patent/EP0001628B1/en
not_active
Expired

1978-10-16
DE
DE7878101157T
patent/DE2862364D1/en
not_active
Expired

1978-10-17
ES
ES474288A
patent/ES474288A1/en
not_active
Expired

1978-10-18
IE
IE2070/78A
patent/IE47958B1/en
not_active
IP Right Cessation

1978-10-18
DK
DK464578A
patent/DK464578A/en
not_active
Application Discontinuation

1978-10-18
IT
IT51567/78A
patent/IT1109318B/en
active

1978-10-18
ZA
ZA785858A
patent/ZA785858B/en
unknown

1978-10-19
JP
JP12792778A
patent/JPS5466697A/en
active
Granted

Also Published As

Publication number
Publication date

ES474288A1
(en)

1980-01-16

IT7851567D0
(en)

1978-10-18

JPH0215552B2
(en)

1990-04-12

IT1109318B
(en)

1985-12-16

JPS5466697A
(en)

1979-05-29

AU531084B2
(en)

1983-08-11

EP0001628A1
(en)

1979-05-02

IE782070L
(en)

1979-04-19

DK464578A
(en)

1979-06-28

DE2862364D1
(en)

1984-02-23

EP0001628B1
(en)

1984-01-18

ZA785858B
(en)

1980-05-28

IE47958B1
(en)

1984-08-08

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