AU4067795A – Squalene synthetase inhibitors
– Google Patents
AU4067795A – Squalene synthetase inhibitors
– Google Patents
Squalene synthetase inhibitors
Info
Publication number
AU4067795A
AU4067795A
AU40677/95A
AU4067795A
AU4067795A
AU 4067795 A
AU4067795 A
AU 4067795A
AU 40677/95 A
AU40677/95 A
AU 40677/95A
AU 4067795 A
AU4067795 A
AU 4067795A
AU 4067795 A
AU4067795 A
AU 4067795A
Authority
AU
Australia
Prior art keywords
synthetase inhibitors
squalene synthetase
squalene
inhibitors
synthetase
Prior art date
1994-12-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU40677/95A
Inventor
Ernest S Hamanaka
Joel M. Hawkins
Cheryl M. Hayward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1994-12-23
Filing date
1995-12-22
Publication date
1996-07-04
1995-12-22
Application filed by Pfizer Inc
filed
Critical
Pfizer Inc
1996-07-04
Publication of AU4067795A
publication
Critical
patent/AU4067795A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P17/00—Drugs for dermatological disorders
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer’s disease or other forms of dementia
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/06—Antihyperlipidemics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/04—Antibacterial agents
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
C07D267/02—Seven-membered rings
C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
C07D267/02—Seven-membered rings
C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
C07D281/02—Seven-membered rings
C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
AU40677/95A
1994-12-23
1995-12-22
Squalene synthetase inhibitors
Abandoned
AU4067795A
(en)
Applications Claiming Priority (4)
Application Number
Priority Date
Filing Date
Title
US36271394A
1994-12-23
1994-12-23
US362713
1994-12-23
WOIB9500424
1995-06-02
PCT/IB1995/000424
WO1996020184A1
(en)
1994-12-23
1995-06-02
Naphthyl-benzoxazepines or -benzothiazepines as squalene synthetase inhibitors
Publications (1)
Publication Number
Publication Date
AU4067795A
true
AU4067795A
(en)
1996-07-04
Family
ID=23427229
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU40677/95A
Abandoned
AU4067795A
(en)
1994-12-23
1995-12-22
Squalene synthetase inhibitors
Country Status (26)
Country
Link
US
(1)
US5770594A
(en)
JP
(1)
JPH10500702A
(en)
KR
(1)
KR960022510A
(en)
CN
(1)
CN1133287A
(en)
AU
(1)
AU4067795A
(en)
BG
(1)
BG100248A
(en)
BR
(1)
BR9505995A
(en)
CA
(1)
CA2207772A1
(en)
CZ
(1)
CZ344795A3
(en)
FI
(1)
FI972696A
(en)
GT
(1)
GT199500058A
(en)
HU
(1)
HUT74672A
(en)
IL
(1)
IL116399A0
(en)
IS
(1)
IS4312A
(en)
LV
(1)
LV11325B
(en)
MA
(1)
MA23746A1
(en)
MX
(1)
MX9704683A
(en)
NO
(1)
NO955288L
(en)
OA
(1)
OA10204A
(en)
PE
(1)
PE60096A1
(en)
PL
(1)
PL311997A1
(en)
SI
(1)
SI9500393A
(en)
SK
(1)
SK158795A3
(en)
TN
(1)
TNSN95133A1
(en)
TR
(1)
TR199501644A2
(en)
WO
(1)
WO1996020184A1
(en)
Families Citing this family (11)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
WO1997048701A1
(en)
*
1996-06-20
1997-12-24
Pfizer Inc.
4,1-benzoxazepines or 4,1-benzothiazepines and their use as squalene synthetase inhibitors
US5965553A
(en)
*
1996-06-20
1999-10-12
Pfizer Inc.
Squalene synthetase inhibitors
DE19716120A1
(en)
*
1997-04-17
1998-10-22
Europ Lab Molekularbiolog
Use of cholesterol-lowering agents
US20060141036A1
(en)
*
1997-12-12
2006-06-29
Andrx Labs Llc
HMG-CoA reductase inhibitor extended release formulation
US6403576B1
(en)
*
1998-08-24
2002-06-11
The United States Of America As Represented By The Secretary Of The Navy
Antifungal and antiparasitic compounds
US20020054871A1
(en)
*
1999-04-12
2002-05-09
Yadong Huang
Methods and compositions for use in the treatment of hyperlipidemia
JP2003523948A
(en)
*
1999-11-04
2003-08-12
アンドルクス コーポレーション
Treatment of amyloid β precursor disorder
US20020107173A1
(en)
*
1999-11-04
2002-08-08
Lawrence Friedhoff
Method of treating amyloid beta precursor disorders
WO2002042296A1
(en)
*
2000-11-21
2002-05-30
Janssen Pharmaceutica N.V.
Farnesyl transferase inhibiting benzoheterocyclic derivatives
WO2008121602A1
(en)
*
2007-03-29
2008-10-09
Smithkline Beecham Corporation
Chemical compounds
GB0803747D0
(en)
*
2008-02-29
2008-04-09
Martin
Enzyme and receptor modulation
Family Cites Families (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
SG48855A1
(en)
*
1992-04-20
1998-05-18
Takeda Chemical Industries Ltd
4,1-benzoxazepin derivatives and their use
AU678503B2
(en)
*
1993-09-24
1997-05-29
Takeda Chemical Industries Ltd.
Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
WO1996009827A2
(en)
*
1994-09-20
1996-04-04
Pfizer Inc.
Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor
1995
1995-06-02
US
US08/860,155
patent/US5770594A/en
not_active
Expired – Fee Related
1995-06-02
BR
BR9505995A
patent/BR9505995A/en
not_active
Application Discontinuation
1995-06-02
SK
SK1587-95A
patent/SK158795A3/en
unknown
1995-06-02
CA
CA002207772A
patent/CA2207772A1/en
not_active
Abandoned
1995-06-02
MX
MX9704683A
patent/MX9704683A/en
not_active
IP Right Cessation
1995-06-02
JP
JP8520314A
patent/JPH10500702A/en
active
Pending
1995-06-02
WO
PCT/IB1995/000424
patent/WO1996020184A1/en
active
Application Filing
1995-12-13
GT
GT199500058A
patent/GT199500058A/en
unknown
1995-12-14
IL
IL11639995A
patent/IL116399A0/en
unknown
1995-12-18
PE
PE1995287390A
patent/PE60096A1/en
not_active
Application Discontinuation
1995-12-18
MA
MA24097A
patent/MA23746A1/en
unknown
1995-12-19
IS
IS4312A
patent/IS4312A/en
unknown
1995-12-21
LV
LVP-95-379A
patent/LV11325B/en
unknown
1995-12-21
BG
BG100248A
patent/BG100248A/en
unknown
1995-12-21
TN
TNTNSN95133A
patent/TNSN95133A1/en
unknown
1995-12-21
PL
PL95311997A
patent/PL311997A1/en
unknown
1995-12-22
HU
HU9503783A
patent/HUT74672A/en
unknown
1995-12-22
NO
NO955288A
patent/NO955288L/en
unknown
1995-12-22
KR
KR1019950054933A
patent/KR960022510A/en
not_active
Application Discontinuation
1995-12-22
TR
TR95/01644A
patent/TR199501644A2/en
unknown
1995-12-22
SI
SI9500393A
patent/SI9500393A/en
unknown
1995-12-22
CZ
CZ953447A
patent/CZ344795A3/en
unknown
1995-12-22
CN
CN95120143A
patent/CN1133287A/en
active
Pending
1995-12-22
OA
OA60759A
patent/OA10204A/en
unknown
1995-12-22
AU
AU40677/95A
patent/AU4067795A/en
not_active
Abandoned
1997
1997-06-23
FI
FI972696A
patent/FI972696A/en
not_active
Application Discontinuation
Also Published As
Publication number
Publication date
GT199500058A
(en)
1997-06-05
PL311997A1
(en)
1996-06-24
IS4312A
(en)
1996-06-24
TNSN95133A1
(en)
1996-02-06
WO1996020184A1
(en)
1996-07-04
FI972696A0
(en)
1997-06-23
LV11325A
(en)
1996-06-20
KR960022510A
(en)
1996-07-18
BG100248A
(en)
1996-07-31
SK158795A3
(en)
1997-01-08
NO955288L
(en)
1996-06-24
OA10204A
(en)
1996-12-18
CN1133287A
(en)
1996-10-16
JPH10500702A
(en)
1998-01-20
MX9704683A
(en)
1997-09-30
HUT74672A
(en)
1997-01-28
BR9505995A
(en)
1997-12-23
CZ344795A3
(en)
1996-09-11
HU9503783D0
(en)
1996-04-29
CA2207772A1
(en)
1996-07-04
FI972696A
(en)
1997-06-23
MA23746A1
(en)
1996-07-01
LV11325B
(en)
1997-02-20
NO955288D0
(en)
1995-12-22
SI9500393A
(en)
1997-04-30
TR199501644A2
(en)
1996-11-21
IL116399A0
(en)
1996-03-31
PE60096A1
(en)
1996-12-28
US5770594A
(en)
1998-06-23
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