AU4986285A – Preparation of 7-amino-3-triazolyl or tetrazolylmethylcephem -4- carboxylic acid derivatives
– Google Patents
AU4986285A – Preparation of 7-amino-3-triazolyl or tetrazolylmethylcephem -4- carboxylic acid derivatives
– Google Patents
Preparation of 7-amino-3-triazolyl or tetrazolylmethylcephem -4- carboxylic acid derivatives
Info
Publication number
AU4986285A
AU4986285A
AU49862/85A
AU4986285A
AU4986285A
AU 4986285 A
AU4986285 A
AU 4986285A
AU 49862/85 A
AU49862/85 A
AU 49862/85A
AU 4986285 A
AU4986285 A
AU 4986285A
AU 4986285 A
AU4986285 A
AU 4986285A
Authority
AU
Australia
Prior art keywords
tetrazolylmethylcephem
triazolyl
amino
preparation
carboxylic acid
Prior art date
1980-09-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU49862/85A
Other versions
AU558649B2
(en
Inventor
Tatsuo Hirakawa
Hiroyuki Imaizumi
Takihiro Inaba
Yoshinori Konishi
Hirokazu Narita
Hiroshi Sadaki
Isamu Saikawa
Masaru Tai
Hideo Taki
Yasuo Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1980-09-25
Filing date
1985-11-13
Publication date
1986-04-24
1980-09-25
Priority claimed from JP55132253A
external-priority
patent/JPS5758689A/en
1980-11-12
Priority claimed from JP55158184A
external-priority
patent/JPS5782393A/en
1980-12-13
Priority claimed from JP55175263A
external-priority
patent/JPS6052755B2/en
1985-11-13
Application filed by Toyama Chemical Co Ltd
filed
Critical
Toyama Chemical Co Ltd
1986-04-24
Publication of AU4986285A
publication
Critical
patent/AU4986285A/en
1987-02-05
Application granted
granted
Critical
1987-02-05
Publication of AU558649B2
publication
Critical
patent/AU558649B2/en
2001-09-17
Anticipated expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/33—Heterocyclic compounds
A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
C07D501/48—Methylene radicals, substituted by hetero rings
C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
AU49862/85A
1980-09-25
1985-11-13
Preparation of 7-amino-3-triazolyl or tetrazolylmethylcephem -4- carboxylic acid derivatives
Expired
AU558649B2
(en)
Applications Claiming Priority (6)
Application Number
Priority Date
Filing Date
Title
JP55132253A
JPS5758689A
(en)
1980-09-25
1980-09-25
Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids
JP55-132253
1980-09-25
JP55158184A
JPS5782393A
(en)
1980-11-12
1980-11-12
7-amino-3-(2-(1,2,3,4-tetrazolyl)methyl)cephem-4-carboxylic acid
JP55-158184
1980-11-12
JP55-175263
1980-12-13
JP55175263A
JPS6052755B2
(en)
1980-12-13
1980-12-13
New cephalosporins
Related Parent Applications (1)
Application Number
Title
Priority Date
Filing Date
AU75438/81A
Division
AU550330B2
(en)
1980-09-25
1981-09-17
Cephalosporin derivatives with a broad antibacterial spectrum 276
Publications (2)
Publication Number
Publication Date
AU4986285A
true
AU4986285A
(en)
1986-04-24
AU558649B2
AU558649B2
(en)
1987-02-05
Family
ID=27316463
Family Applications (3)
Application Number
Title
Priority Date
Filing Date
AU75438/81A
Expired
AU550330B2
(en)
1980-09-25
1981-09-17
Cephalosporin derivatives with a broad antibacterial spectrum 276
AU49862/85A
Expired
AU558649B2
(en)
1980-09-25
1985-11-13
Preparation of 7-amino-3-triazolyl or tetrazolylmethylcephem -4- carboxylic acid derivatives
AU49861/85A
Expired
AU568033B2
(en)
1980-09-25
1985-11-13
3-((1,2,4-triazolyl or 2 (1,2,3,4-tetrazolyl) methyl) cephalosporins
Family Applications Before (1)
Application Number
Title
Priority Date
Filing Date
AU75438/81A
Expired
AU550330B2
(en)
1980-09-25
1981-09-17
Cephalosporin derivatives with a broad antibacterial spectrum 276
Family Applications After (1)
Application Number
Title
Priority Date
Filing Date
AU49861/85A
Expired
AU568033B2
(en)
1980-09-25
1985-11-13
3-((1,2,4-triazolyl or 2 (1,2,3,4-tetrazolyl) methyl) cephalosporins
Country Status (27)
Country
Link
US
(4)
US4489072A
(en)
KR
(1)
KR860000932B1
(en)
AR
(1)
AR240645A1
(en)
AT
(4)
AT375082B
(en)
AU
(3)
AU550330B2
(en)
CA
(2)
CA1204735A
(en)
CH
(4)
CH652130A5
(en)
DD
(2)
DD208351A5
(en)
DE
(5)
DE3152935C2
(en)
DK
(1)
DK163877C
(en)
EG
(1)
EG17373A
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ES
(4)
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(en)
FI
(2)
FI75575C
(en)
FR
(2)
FR2509310B1
(en)
GB
(3)
GB2089339B
(en)
HU
(1)
HU185850B
(en)
IN
(4)
IN155375B
(en)
IT
(1)
IT1172201B
(en)
LU
(1)
LU83650A1
(en)
MX
(1)
MX155025A
(en)
NL
(1)
NL8104386A
(en)
NO
(1)
NO161117C
(en)
NZ
(1)
NZ198350A
(en)
PH
(5)
PH18072A
(en)
PT
(1)
PT73727B
(en)
RO
(4)
RO86823B
(en)
SE
(5)
SE453090B
(en)
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patent/NZ198350A/en
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CA
CA000386066A
patent/CA1204735A/en
not_active
Expired
1981-09-16
GB
GB8128011A
patent/GB2089339B/en
not_active
Expired
1981-09-16
PH
PH26215A
patent/PH18072A/en
unknown
1981-09-17
AU
AU75438/81A
patent/AU550330B2/en
not_active
Expired
1981-09-19
IN
IN1045/CAL/81A
patent/IN155375B/en
unknown
1981-09-23
DE
DE3152935A
patent/DE3152935C2/de
not_active
Expired – Lifetime
1981-09-23
DE
DE3152932A
patent/DE3152932C2/de
not_active
Expired – Lifetime
1981-09-23
NL
NL8104386A
patent/NL8104386A/en
not_active
Application Discontinuation
1981-09-23
DE
DE3152934A
patent/DE3152934C2/de
not_active
Expired – Lifetime
1981-09-23
DE
DE19813137854
patent/DE3137854A1/en
active
Granted
1981-09-23
IT
IT49348/81A
patent/IT1172201B/en
active
1981-09-23
US
US06/304,912
patent/US4489072A/en
not_active
Expired – Lifetime
1981-09-23
DE
DE3152931A
patent/DE3152931C2/de
not_active
Expired
1981-09-24
FI
FI812980A
patent/FI75575C/en
not_active
IP Right Cessation
1981-09-24
MX
MX7609A
patent/MX155025A/en
unknown
1981-09-24
AT
AT0410981A
patent/AT375082B/en
not_active
IP Right Cessation
1981-09-24
ES
ES505760A
patent/ES8301998A1/en
not_active
Expired
1981-09-24
LU
LU83650A
patent/LU83650A1/en
unknown
1981-09-24
NO
NO813252A
patent/NO161117C/en
unknown
1981-09-24
PT
PT73727A
patent/PT73727B/en
unknown
1981-09-24
DK
DK421881A
patent/DK163877C/en
active
1981-09-24
SE
SE8105658A
patent/SE453090B/en
not_active
IP Right Cessation
1981-09-24
HU
HU812759A
patent/HU185850B/en
unknown
1981-09-25
FR
FR8118156A
patent/FR2509310B1/en
not_active
Expired
1981-09-25
RO
RO112111A
patent/RO86823B/en
unknown
1981-09-25
CH
CH4520/84A
patent/CH652130A5/en
not_active
IP Right Cessation
1981-09-25
DD
DD81247292A
patent/DD208351A5/en
unknown
1981-09-25
RO
RO81105405A
patent/RO82689A/en
unknown
1981-09-25
CH
CH6202/81A
patent/CH652129A5/en
not_active
IP Right Cessation
1981-09-25
CH
CH4519/84A
patent/CH651837A5/en
not_active
IP Right Cessation
1981-09-25
RO
RO112113A
patent/RO86825B/en
unknown
1981-09-25
CH
CH4521/84A
patent/CH652128A5/en
not_active
IP Right Cessation
1981-09-25
RO
RO112112A
patent/RO86824B/en
unknown
1981-09-25
DD
DD81233599A
patent/DD202436A5/en
unknown
1981-09-26
EG
EG543/81A
patent/EG17373A/en
active
1982
1982-08-02
ES
ES514671A
patent/ES8306157A1/en
not_active
Expired
1982-08-02
ES
ES514670A
patent/ES514670A0/en
active
Granted
1982-08-02
ES
ES514669A
patent/ES514669A0/en
active
Granted
1982-09-22
FR
FR8215992A
patent/FR2511377B1/en
not_active
Expired
1983
1983-01-07
AR
AR29180883A
patent/AR240645A1/en
active
1983-02-18
AT
AT0055483A
patent/AT378961B/en
not_active
IP Right Cessation
1983-02-18
AT
AT0055683A
patent/AT378193B/en
not_active
IP Right Cessation
1983-02-18
AT
AT0055583A
patent/AT378962B/en
not_active
IP Right Cessation
1983-06-17
PH
PH29075A
patent/PH19251A/en
unknown
1983-06-17
PH
PH29076A
patent/PH19147A/en
unknown
1983-06-17
PH
PH29077A
patent/PH20221A/en
unknown
1983-06-17
PH
PH29078A
patent/PH18484A/en
unknown
1983-09-01
CA
CA000435930A
patent/CA1200541A/en
not_active
Expired
1984
1984-01-27
GB
GB08402250A
patent/GB2136420B/en
not_active
Expired
1984-01-27
GB
GB08402249A
patent/GB2135304B/en
not_active
Expired
1984-08-29
IN
IN602/CAL/84A
patent/IN158590B/en
unknown
1984-08-29
IN
IN601/CAL/84A
patent/IN158589B/en
unknown
1984-08-29
IN
IN603/CAL/84A
patent/IN159126B/en
unknown
1984-09-26
US
US06/654,681
patent/US4673738A/en
not_active
Expired – Lifetime
1985
1985-11-13
AU
AU49862/85A
patent/AU558649B2/en
not_active
Expired
1985-11-13
AU
AU49861/85A
patent/AU568033B2/en
not_active
Expired
1986
1986-01-16
SE
SE8600193A
patent/SE468479B/en
not_active
IP Right Cessation
1986-01-16
SE
SE8600192A
patent/SE468478B/en
not_active
IP Right Cessation
1986-01-16
SE
SE8600195A
patent/SE468477B/en
not_active
IP Right Cessation
1986-01-16
SE
SE8600194A
patent/SE468476B/en
not_active
IP Right Cessation
1986-03-29
KR
KR1019860002383A
patent/KR860000932B1/en
not_active
IP Right Cessation
1987
1987-01-15
FI
FI870153A
patent/FI80041C/en
not_active
IP Right Cessation
1987-03-06
US
US07/022,433
patent/US4879381A/en
not_active
Expired – Lifetime
1991
1991-05-24
US
US07/707,221
patent/US5144027A/en
not_active
Expired – Fee Related
Also Published As
Publication number
Publication date
SE8600192L
(en)
1986-01-16
US4489072A
(en)
1984-12-18
FI812980L
(en)
1982-03-26
PH20221A
(en)
1986-10-23
IT1172201B
(en)
1987-06-18
MX155025A
(en)
1988-01-20
SE468477B
(en)
1993-01-25
NL8104386A
(en)
1982-04-16
FI80041C
(en)
1990-04-10
DE3137854A1
(en)
1982-04-15
NO813252L
(en)
1982-03-26
ES505760A0
(en)
1983-01-01
FR2509310A1
(en)
1983-01-14
DE3152935C2
(en)
1992-07-16
RO82689B
(en)
1983-10-30
DD208351A5
(en)
1984-05-02
AT375082B
(en)
1984-06-25
ES514671A0
(en)
1983-05-01
FI80041B
(en)
1989-12-29
SE468479B
(en)
1993-01-25
FR2511377B1
(en)
1985-12-13
ES8306157A1
(en)
1983-05-01
CH652128A5
(en)
1985-10-31
SE8600194L
(en)
1986-01-16
IT8149348D0
(en)
1981-09-23
DE3152932C2
(en)
1990-02-08
US4879381A
(en)
1989-11-07
SE8600193D0
(en)
1986-01-16
DE3152934C2
(en)
1990-01-18
FR2509310B1
(en)
1985-08-02
RO82689A
(en)
1983-11-01
NO161117C
(en)
1989-07-05
CA1204735A
(en)
1986-05-20
DK163877C
(en)
1992-09-14
AU7543881A
(en)
1982-04-01
GB8402249D0
(en)
1984-02-29
LU83650A1
(en)
1982-01-21
RO86824B
(en)
1985-05-31
ATA410981A
(en)
1983-11-15
GB2089339A
(en)
1982-06-23
SE8600195D0
(en)
1986-01-16
RO86825A
(en)
1985-05-20
NO161117B
(en)
1989-03-28
IN159126B
(en)
1987-03-28
US5144027A
(en)
1992-09-01
GB2136420A
(en)
1984-09-19
IN158590B
(en)
1986-12-13
EG17373A
(en)
1990-12-30
PH18072A
(en)
1985-03-18
SE8600195L
(en)
1986-01-16
SE468476B
(en)
1993-01-25
GB2089339B
(en)
1985-04-24
PH19147A
(en)
1986-01-15
RO86823B
(en)
1985-05-31
GB2135304A
(en)
1984-08-30
DK163877B
(en)
1992-04-13
CH652129A5
(en)
1985-10-31
RO86825B
(en)
1985-05-31
KR860000932B1
(en)
1986-07-19
PH19251A
(en)
1986-02-17
US4673738A
(en)
1987-06-16
SE468478B
(en)
1993-01-25
DE3152931C2
(en)
1989-10-05
NZ198350A
(en)
1985-02-28
ATA55683A
(en)
1984-11-15
ES8306156A1
(en)
1983-05-01
FR2511377A1
(en)
1983-02-18
SE8600194D0
(en)
1986-01-16
HU185850B
(en)
1985-04-28
AT378961B
(en)
1985-10-25
SE8600192D0
(en)
1986-01-16
SE8600193L
(en)
1986-01-16
GB2136420B
(en)
1985-05-01
ATA55483A
(en)
1985-03-15
GB2135304B
(en)
1985-03-27
AR240645A1
(en)
1990-07-31
DD202436A5
(en)
1983-09-14
ES8306155A1
(en)
1983-05-01
IN158589B
(en)
1986-12-13
PT73727B
(en)
1982-12-30
FI870153A
(en)
1987-01-15
AT378962B
(en)
1985-10-25
RO86823A
(en)
1985-05-20
DE3137854C2
(en)
1987-06-19
AT378193B
(en)
1985-06-25
AU4986185A
(en)
1986-03-20
FI870153A0
(en)
1987-01-15
SE453090B
(en)
1988-01-11
ATA55583A
(en)
1985-03-15
FI75575B
(en)
1988-03-31
SE8105658L
(en)
1982-05-05
CA1200541A
(en)
1986-02-11
ES514670A0
(en)
1983-05-01
IN155375B
(en)
1985-01-19
FI75575C
(en)
1988-07-11
ES514669A0
(en)
1983-05-01
AU558649B2
(en)
1987-02-05
PT73727A
(en)
1981-10-01
GB8402250D0
(en)
1984-02-29
DK421881A
(en)
1982-04-15
RO86824A
(en)
1985-05-20
ES8301998A1
(en)
1983-01-01
PH18484A
(en)
1985-08-02
CH652130A5
(en)
1985-10-31
CH651837A5
(en)
1985-10-15
AU568033B2
(en)
1987-12-10
AU550330B2
(en)
1986-03-20
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2002-04-18
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Patent ceased section 143(a) (annual fees not paid) or expired