AU5139490A – Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)- en-20-yn-3-one
– Google Patents
AU5139490A – Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)- en-20-yn-3-one
– Google Patents
Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)- en-20-yn-3-one
Info
Publication number
AU5139490A
AU5139490A
AU51394/90A
AU5139490A
AU5139490A
AU 5139490 A
AU5139490 A
AU 5139490A
AU 51394/90 A
AU51394/90 A
AU 51394/90A
AU 5139490 A
AU5139490 A
AU 5139490A
AU 5139490 A
AU5139490 A
AU 5139490A
Authority
AU
Australia
Prior art keywords
compound
pregn
hydroxy
methyl
pharmaceutical composition
Prior art date
1989-03-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU51394/90A
Other versions
AU625083B2
(en
Inventor
Gerard Arnoud Jozef Maria Theresia Sas
Emile Martin Van Doornum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme BV
Original Assignee
Merck Sharp and Dohme BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1989-03-18
Filing date
1990-03-16
Publication date
1990-09-20
Family has litigation
First worldwide family litigation filed
litigation
Critical
https://patents.darts-ip.com/?family=19854317&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU5139490(A)
«Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
1990-03-16
Application filed by Merck Sharp and Dohme BV
filed
Critical
Merck Sharp and Dohme BV
1990-09-20
Publication of AU5139490A
publication
Critical
patent/AU5139490A/en
1992-07-02
Application granted
granted
Critical
1992-07-02
Publication of AU625083B2
publication
Critical
patent/AU625083B2/en
2007-09-13
Assigned to N.V. ORGANON
reassignment
N.V. ORGANON
Alteration of Name(s) in Register under S187
Assignors: AKZO N.V.
2012-01-12
Assigned to MSD OSS B.V.
reassignment
MSD OSS B.V.
Request to Amend Deed and Register
Assignors: N.V. ORGANON
2013-06-13
Assigned to MERCK SHARP & DOHME B.V.
reassignment
MERCK SHARP & DOHME B.V.
Request to Amend Deed and Register
Assignors: MSD OSS B.V.
2015-03-16
Adjusted expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P15/00—Drugs for genital or sexual disorders; Contraceptives
A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P15/00—Drugs for genital or sexual disorders; Contraceptives
A61P15/18—Feminine contraceptives
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P19/00—Drugs for skeletal disorders
A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget’s disease
A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget’s disease for osteoporosis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P37/00—Drugs for immunological or allergic disorders
A61P37/02—Immunomodulators
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P5/00—Drugs for disorders of the endocrine system
Abstract
A pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7 alpha ,17 alpha )-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-one, characterized in that the said compound is crystalline pure and completely or virtually completely free from the other crystalline form.
AU51394/90A
1989-03-18
1990-03-16
Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)- en-20-yn-3-one
Expired
AU625083B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
NL8900673
1989-03-18
NL8900673
1989-03-18
Publications (2)
Publication Number
Publication Date
AU5139490A
true
AU5139490A
(en)
1990-09-20
AU625083B2
AU625083B2
(en)
1992-07-02
Family
ID=19854317
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU51394/90A
Expired
AU625083B2
(en)
1989-03-18
1990-03-16
Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)- en-20-yn-3-one
Country Status (17)
Country
Link
US
(1)
US5037817A
(en)
EP
(1)
EP0389035B1
(en)
JP
(2)
JP3139709B2
(en)
KR
(1)
KR0183401B1
(en)
AT
(1)
ATE98490T1
(en)
AU
(1)
AU625083B2
(en)
CA
(1)
CA2011452C
(en)
DE
(1)
DE69005165T2
(en)
DK
(1)
DK0389035T3
(en)
ES
(1)
ES2062292T3
(en)
FI
(1)
FI94865C
(en)
HK
(1)
HK1002019A1
(en)
IE
(1)
IE63051B1
(en)
MX
(1)
MX9203787A
(en)
NZ
(1)
NZ232946A
(en)
PT
(1)
PT93488B
(en)
ZA
(1)
ZA901674B
(en)
Families Citing this family (18)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DK0613687T3
(en)
*
1993-03-05
1999-12-06
Akzo Nobel Nv
Use of pregnancy derivative for the treatment of tumors
US6242434B1
(en)
*
1997-08-08
2001-06-05
Bone Care International, Inc.
24-hydroxyvitamin D, analogs and uses thereof
IL123984A
(en)
*
1997-04-22
2004-09-27
Akzo Nobel Nv
Pharmaceutical dosage units comprising tibolone and a pharmaceutically acceptable carrier
WO2000023460A1
(en)
*
1998-10-16
2000-04-27
Akzo Nobel N.V.
HIGH PURITY COMPOSITION COMPRISING (7α,17α)- 17-HYDROXY- 7-METHYL- 19-NOR-17-PREGN- 5(10)-EN-20-YN-3-ONE
US7045513B1
(en)
1999-03-18
2006-05-16
Genelabs Technologies, Inc.
DHEA composition and method
IL139386A
(en)
*
1999-03-18
2006-08-01
Genelabs Tech Inc
Dhea composition and method
TWI265167B
(en)
*
1999-11-29
2006-11-01
Akzo Nobel Nv
3-methylene steroid derivatives
US20040229854A1
(en)
*
2000-11-28
2004-11-18
Pieter Haan De
Immediate release dosage form for HRT
DK1444247T3
(en)
*
2001-10-18
2007-09-24
Norton Healthcare Ltd
tibolone formulations
GB0125061D0
(en)
*
2001-10-18
2001-12-12
Norton Healthcare Ltd
Pharmaceutical composition
BR0306789A
(en)
*
2002-01-22
2004-12-28
Akzo Nobel Nv
Tibolone use and method of treating estrogen deficiency complaints in female patients
GB0304927D0
(en)
2003-03-04
2003-04-09
Resolution Chemicals Ltd
Process for the production of tibolone
CN1324041C
(en)
*
2003-04-01
2007-07-04
上海迪赛诺医药科技开发有限公司
Preparation method of tibolong crystal type I
WO2004103378A1
(en)
*
2003-05-23
2004-12-02
Akzo Nobel N.V.
Immediate-release pharmaceutical dosage form comprising polymorphous tibolone
EP1883648A1
(en)
*
2005-05-23
2008-02-06
Newchem S.p.A.
Process for the preparation of pure crystalline tibolone
EP1821571A1
(en)
*
2006-02-15
2007-08-22
Oticon A/S
Loop antenna for in the ear audio device
ITMI20130120A1
(en)
*
2013-01-25
2014-07-26
Ind Chimica Srl
PROCESS FOR PREPARATION IN THE CRYSTAL FORM OF TIBOLONE, (7ALFA, 17ALFA) -17-HYDROSSI-7-METHYL-19-NORPREGN-5 (10) -EN-20-IN-3-ONE
BR112018072371A2
(en)
2016-05-04
2019-02-19
Mithra Pharmaceuticals S A
mannitol use, pharmaceutical composition or use, method for preparing a solid dosage form comprising tibolone
Family Cites Families (6)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
BE665514A
(en)
*
1964-06-16
US4933168A
(en)
*
1975-05-27
1990-06-12
Syntex Pharmaceuticals International Limited
Stable, crystalline flunisolide
US4273710A
(en)
*
1979-05-21
1981-06-16
Syntex Corporation
Process for preparing flunisolide
US4391755A
(en)
*
1982-01-18
1983-07-05
E. R. Squibb & Sons, Inc.
Steroid monohydrates, formulations containing same and method
US4447426A
(en)
*
1982-01-18
1984-05-08
E. R. Squibb & Sons, Inc.
Steroid monohydrates, formulations containing same and method
US4701450A
(en)
*
1984-03-21
1987-10-20
Akzo N.V.
Steroids for use as immunomodulators
1990
1990-02-27
IE
IE70990A
patent/IE63051B1/en
not_active
IP Right Cessation
1990-03-05
CA
CA002011452A
patent/CA2011452C/en
not_active
Expired – Lifetime
1990-03-05
ZA
ZA901674A
patent/ZA901674B/en
unknown
1990-03-12
DE
DE90200574T
patent/DE69005165T2/en
not_active
Expired – Lifetime
1990-03-12
ES
ES90200574T
patent/ES2062292T3/en
not_active
Expired – Lifetime
1990-03-12
AT
AT90200574T
patent/ATE98490T1/en
not_active
IP Right Cessation
1990-03-12
DK
DK90200574.3T
patent/DK0389035T3/en
active
1990-03-12
EP
EP90200574A
patent/EP0389035B1/en
not_active
Expired – Lifetime
1990-03-14
JP
JP02063921A
patent/JP3139709B2/en
not_active
Expired – Lifetime
1990-03-15
US
US07/494,089
patent/US5037817A/en
not_active
Expired – Lifetime
1990-03-16
PT
PT93488A
patent/PT93488B/en
not_active
IP Right Cessation
1990-03-16
NZ
NZ232946A
patent/NZ232946A/en
unknown
1990-03-16
AU
AU51394/90A
patent/AU625083B2/en
not_active
Expired
1990-03-16
FI
FI901328A
patent/FI94865C/en
active
IP Right Grant
1990-03-17
KR
KR1019900003574A
patent/KR0183401B1/en
not_active
IP Right Cessation
1992
1992-06-29
MX
MX9203787A
patent/MX9203787A/en
unknown
1998
1998-02-11
HK
HK98101031A
patent/HK1002019A1/en
not_active
IP Right Cessation
2000
2000-10-17
JP
JP2000316716A
patent/JP2001139473A/en
active
Pending
Also Published As
Publication number
Publication date
PT93488B
(en)
1996-02-29
JP2001139473A
(en)
2001-05-22
US5037817A
(en)
1991-08-06
KR900013950A
(en)
1990-10-22
FI94865C
(en)
1995-11-10
FI94865B
(en)
1995-07-31
EP0389035A1
(en)
1990-09-26
CA2011452C
(en)
1999-05-25
DE69005165T2
(en)
1994-05-05
ES2062292T3
(en)
1994-12-16
JP3139709B2
(en)
2001-03-05
PT93488A
(en)
1990-11-07
IE63051B1
(en)
1995-03-22
NZ232946A
(en)
1991-08-27
ATE98490T1
(en)
1994-01-15
JPH0347195A
(en)
1991-02-28
KR0183401B1
(en)
1999-05-01
DK0389035T3
(en)
1994-02-14
MX9203787A
(en)
1992-07-01
FI901328A0
(en)
1990-03-16
ZA901674B
(en)
1990-12-28
IE900709L
(en)
1990-09-18
CA2011452A1
(en)
1990-09-18
HK1002019A1
(en)
1998-07-24
AU625083B2
(en)
1992-07-02
DE69005165D1
(en)
1994-01-27
EP0389035B1
(en)
1993-12-15
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Title
AU625083B2
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1992-07-02
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Legal Events
Date
Code
Title
Description
2000-08-24
NC
Extension of term for standard patent requested (sect. 70)
Free format text:
PRODUCT NAME: LIVIAL CONTAINING THE COMPOUND TIBOLONE
2000-08-31
NDA
Extension of term for standard patent accepted (sect.70)
Free format text:
PRODUCT NAME: LIVIAL CONTAINING THE COMPOUND TIBOLONE
Extension date:
20150316
2001-01-25
NDB
Extension of term for standard patent granted (sect.76)
Free format text:
PRODUCT NAME: LIVIAL CONTAINING THE COMPOUND TIBOLONE
Extension date:
20150316
