AU531232B2 - Creación de Inventos y Patentes con Inteligencia Artificial

AU531232B2 – Quinoxalinone and cyclobuteno- quinoxaline- dione derivatives
– Google Patents

AU531232B2 – Quinoxalinone and cyclobuteno- quinoxaline- dione derivatives
– Google Patents
Quinoxalinone and cyclobuteno- quinoxaline- dione derivatives

Info

Publication number
AU531232B2

AU531232B2
AU58786/80A
AU5878680A
AU531232B2
AU 531232 B2
AU531232 B2
AU 531232B2
AU 58786/80 A
AU58786/80 A
AU 58786/80A
AU 5878680 A
AU5878680 A
AU 5878680A
AU 531232 B2
AU531232 B2
AU 531232B2
Authority
AU
Australia
Prior art keywords
alkyl
hydroxyl
hydrogen
halogen
acyl
Prior art date
1979-05-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU58786/80A
Other versions

AU5878680A
(en

Inventor
Wolfgang Bartsch
Wolfgang Kampe
Egon Roesch
Carl Heinz Ross
Gisbert Sponer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Roche Diagnostics GmbH

Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1979-05-31
Filing date
1980-05-27
Publication date
1983-08-18

1980-05-27
Application filed by Boehringer Mannheim GmbH
filed
Critical
Boehringer Mannheim GmbH

1980-12-04
Publication of AU5878680A
publication
Critical
patent/AU5878680A/en

1983-08-18
Application granted
granted
Critical

1983-08-18
Publication of AU531232B2
publication
Critical
patent/AU531232B2/en

2000-05-27
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems

C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems

C07D241/40—Benzopyrazines

C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Abstract

An aminopropanol compound of the formula wherein R1 and R2 are individually selected from hydrogen and lower alkyl; or R1 and R2 together represent an alkylene radical; R3 is hydrogen or acyl; A is one of the following structures wherein R4 is hydrogen or lower alkyl optionally substituted by hydroxyl halogen and lower alkylthio; and R5 and R6 are individually selected from lower alkyl; B is alkylamino which optionally carries a phenyl and a phenoxy radical optionally substituted by at at least one of halogen, hydroxyl or lower alkyl, lower acyl, lower alkylthio, acylamino, aminocarbonyl, lower alkoxy, lower alkenyloxy, phenoxy, lower alkenyl, lower alkylsulphonyl, lower alkylsulphinyl or haloalkyl; or B is an aryl- or heteroaryloxymethylpiperidine radical optionally substituted by at least one of halogen hydroxyl or lower alkyl, hydroxyl alkyl or carboxamido alkyl, or by lower alkoxy, lower acyl, amino, carboxamido, lower alkylcarbonylamido or lower alkylsulphonylamino; and the pharmacologically acceptable salts thereof, are outstandingly effective beta blockers and blood-pressure depressants.

AU58786/80A
1979-05-31
1980-05-27
Quinoxalinone and cyclobuteno- quinoxaline- dione derivatives

Ceased

AU531232B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

DE29220846

1979-05-31

DE19792922084

DE2922084A1
(en)

1979-05-31
1979-05-31

NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number
Publication Date

AU5878680A

AU5878680A
(en)

1980-12-04

AU531232B2
true

AU531232B2
(en)

1983-08-18

Family
ID=6072095
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU58786/80A
Ceased

AU531232B2
(en)

1979-05-31
1980-05-27
Quinoxalinone and cyclobuteno- quinoxaline- dione derivatives

Country Status (11)

Country
Link

US
(1)

US4438116A
(en)

EP
(1)

EP0019918B1
(en)

JP
(1)

JPS55162783A
(en)

AT
(1)

ATE4595T1
(en)

AU
(1)

AU531232B2
(en)

CA
(1)

CA1145338A
(en)

DD
(1)

DD151165A5
(en)

DE
(2)

DE2922084A1
(en)

ES
(1)

ES491914A0
(en)

FI
(1)

FI801689A
(en)

ZA
(1)

ZA803243B
(en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPH0276860A
(en)

1987-10-05
1990-03-16
Toyo Jozo Co Ltd
6-substituted-alkoxy-2-oxo-1,2-dihydroquinoxaline derivative

JPH09502166A
(en)

1993-07-31
1997-03-04
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー

2-Benzoheterocyclyloxy or thiopropanolamine derivatives having adrenergic receptor agonist activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AT242150B
(en)

1963-07-10
1965-08-25
Donau Pharmazie Gmbh

Process for the preparation of new, substituted dihydroquinoxalones (2) and their salts and quaternary ammonium compounds

US3366628A
(en)

1966-06-23
1968-01-30
American Home Prod
1, 2-dihydro-1-polyhydroxyalkyl-2-quinoxalinones

DE1670919A1
(en)

1967-09-09
1971-04-08
Bayer Ag

Process for the production of novel polycyclic, heterocyclic compounds

US3635971A
(en)

1970-06-18
1972-01-18
Abbott Lab
3 (3 4-dihydro-3-oxo-2-quinoxalinyl) propionamides

CH624395A5
(en)

1976-01-08
1981-07-31
Ciba Geigy Ag

US4146630A
(en)

1976-11-12
1979-03-27
Boehringer Mannheim Gmbh
Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers

1979

1979-05-31
DE
DE19792922084
patent/DE2922084A1/en
not_active
Withdrawn

1980

1980-05-16
CA
CA000352092A
patent/CA1145338A/en
not_active
Expired

1980-05-26
FI
FI801689A
patent/FI801689A/en
not_active
Application Discontinuation

1980-05-27
AU
AU58786/80A
patent/AU531232B2/en
not_active
Ceased

1980-05-28
ES
ES491914A
patent/ES491914A0/en
active
Granted

1980-05-29
DD
DD80221448A
patent/DD151165A5/en
unknown

1980-05-29
EP
EP80103001A
patent/EP0019918B1/en
not_active
Expired

1980-05-29
DE
DE8080103001T
patent/DE3064744D1/en
not_active
Expired

1980-05-29
AT
AT80103001T
patent/ATE4595T1/en
not_active
IP Right Cessation

1980-05-30
ZA
ZA00803243A
patent/ZA803243B/en
unknown

1980-05-30
JP
JP7164680A
patent/JPS55162783A/en
active
Pending

1981

1981-09-16
US
US06/302,894
patent/US4438116A/en
not_active
Expired – Fee Related

Also Published As

Publication number
Publication date

JPS55162783A
(en)

1980-12-18

EP0019918B1
(en)

1983-09-07

ATE4595T1
(en)

1983-09-15

EP0019918A1
(en)

1980-12-10

US4438116A
(en)

1984-03-20

ES8101054A1
(en)

1980-12-16

CA1145338A
(en)

1983-04-26

ZA803243B
(en)

1981-06-24

AU5878680A
(en)

1980-12-04

ES491914A0
(en)

1980-12-16

DE3064744D1
(en)

1983-10-13

DE2922084A1
(en)

1980-12-11

DD151165A5
(en)

1981-10-08

FI801689A
(en)

1980-12-01

Información de contacto