AU540147B2

AU540147B2 – Cyclopentanonealkenoic acid derivatives
– Google Patents

AU540147B2 – Cyclopentanonealkenoic acid derivatives
– Google Patents
Cyclopentanonealkenoic acid derivatives

Info

Publication number
AU540147B2

AU540147B2
AU69957/81A
AU6995781A
AU540147B2
AU 540147 B2
AU540147 B2
AU 540147B2
AU 69957/81 A
AU69957/81 A
AU 69957/81A
AU 6995781 A
AU6995781 A
AU 6995781A
AU 540147 B2
AU540147 B2
AU 540147B2
Authority
AU
Australia
Prior art keywords
cyclopentanonealkenoic
acid derivatives
derivatives
acid
cyclopentanonealkenoic acid
Prior art date
1980-04-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU69957/81A
Other versions

AU6995781A
(en

Inventor
John Bradshaw
Eric William Collington
Peter Hallett
Norman Frank Hayes
John Wallis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Glaxo Group Ltd

Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1980-04-30
Filing date
1981-04-29
Publication date
1984-11-01

1981-04-29
Application filed by Glaxo Group Ltd
filed
Critical
Glaxo Group Ltd

1981-11-05
Publication of AU6995781A
publication
Critical
patent/AU6995781A/en

1984-11-01
Application granted
granted
Critical

1984-11-01
Publication of AU540147B2
publication
Critical
patent/AU540147B2/en

2001-04-29
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

239000002253
acid
Substances

0.000
title
1

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms

C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms

C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A61P11/08—Bronchodilators

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P27/00—Drugs for disorders of the senses

A61P27/02—Ophthalmic agents

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P7/00—Drugs for disorders of the blood or the extracellular fluid

A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/08—Vasodilators for multiple indications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C17/00—Preparation of halogenated hydrocarbons

C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens

C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups

C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups

C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds

C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation

C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms

C07D267/02—Seven-membered rings

C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4

C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms

C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms

C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms

C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems

C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings

C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D309/10—Oxygen atoms

C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom

C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms

C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom

C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms

C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen

C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom

C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms

C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom

C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms

C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings

C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

D—TEXTILES; PAPER

D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING

D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS

D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof

D01F6/58—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products

D01F6/62—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters

D01F6/625—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters derived from hydroxy-carboxylic acids, e.g. lactones

AU69957/81A
1980-04-30
1981-04-29
Cyclopentanonealkenoic acid derivatives

Ceased

AU540147B2
(en)

Applications Claiming Priority (4)

Application Number
Priority Date
Filing Date
Title

GB8014256

1980-04-30

GB8014256

1980-04-30

GB8100326

1981-01-07

GB8100326

1981-01-07

Publications (2)

Publication Number
Publication Date

AU6995781A

AU6995781A
(en)

1981-11-05

AU540147B2
true

AU540147B2
(en)

1984-11-01

Family
ID=26275368
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU69957/81A
Ceased

AU540147B2
(en)

1980-04-30
1981-04-29
Cyclopentanonealkenoic acid derivatives

Country Status (21)

Country
Link

US
(2)

US4342756A
(en)

JP
(2)

JPS5718671A
(en)

KR
(1)

KR850000214B1
(en)

AT
(1)

ATA191781A
(en)

AU
(1)

AU540147B2
(en)

BE
(1)

BE888645A
(en)

CH
(1)

CH646965A5
(en)

DE
(1)

DE3117087A1
(en)

DK
(1)

DK189881A
(en)

ES
(2)

ES501740A0
(en)

FI
(1)

FI78293C
(en)

FR
(1)

FR2481703B1
(en)

GB
(1)

GB2075503B
(en)

IE
(1)

IE51241B1
(en)

IL
(1)

IL62734A
(en)

IT
(1)

IT1170929B
(en)

NL
(1)

NL8102116A
(en)

NO
(1)

NO811470L
(en)

NZ
(1)

NZ196966A
(en)

PT
(1)

PT72951B
(en)

SE
(1)

SE8102731L
(en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

ES482357A1
(en)

*

1978-07-11
1980-08-16
Glaxo Group Ltd
Prostanoid compounds and compositions

US4438111A
(en)

1980-01-09
1984-03-20
Glaxo Group Limited
Prostanoid compounds and pharmaceutical formulations

ZA81114B
(en)

1980-01-09
1982-01-27
Glaxo Group Ltd
Prostanoid compounds and their preparation and pharmaceutical formalation

CA1191134A
(en)

*

1981-04-29
1985-07-30
Eric W. Collington
Aminocyclopentanol acids and esters and their preparation and pharmaceutical formulation

CA1190926A
(en)

*

1981-09-16
1985-07-23
Christopher J. Wallis
Aminocyclopentane esters and their preparation and pharmaceutical formulation

US4410521A
(en)

*

1981-09-16
1983-10-18
Glaxo Group Limited
Aminocyclopentane esters and pharmaceutical formulations

IL67041A
(en)

*

1981-10-29
1988-03-31
Glaxo Group Ltd
2-aminocyclopentane alkanoic and alkenoic acid esters,process for their preparation and pharmaceutical compositions containing them

GR77727B
(en)

*

1981-10-29
1984-09-25
Glaxo Group Ltd

US4837234A
(en)

*

1981-12-23
1989-06-06
National Research Development Corporation
Prostaglandins

GB2113678B
(en)

*

1981-12-23
1985-06-19
Nat Res Dev
Prostaglandins

GB2127406B
(en)

*

1982-09-16
1986-03-05
Glaxo Group Ltd
Piperidinlycyclopentanolheptenoic acid salt

AU576476B2
(en)

*

1982-09-16
1988-09-01
Glaxo Group Limited
Piperidinylcyclopentanol heptenoic acid salt

AT387220B
(en)

*

1982-10-28
1988-12-27
Glaxo Group Ltd

METHOD FOR PRODUCING AMINOCYCLOPENTANE ACIDS

GB8307099D0
(en)

*

1983-03-15
1983-04-20
Glaxo Group Ltd
Carbocyclic compounds

LU85528A1
(en)

*

1983-09-06
1985-04-29
Glaxo Group Ltd

AMINOCYCLOPENTANS AND THEIR PREPARATION PROCESS

GB2167404A
(en)

*

1984-10-26
1986-05-29
Glaxo Group Ltd
Prostanoid aminocyclopentane alkenoic acids and esters, their preparation and pharmaceutical formulation

GB8601985D0
(en)

*

1986-01-28
1986-03-05
Glaxo Group Ltd
Chemical process

GB8625326D0
(en)

*

1986-10-22
1986-11-26
Glaxo Group Ltd
Medicaments

GB8715333D0
(en)

*

1987-06-30
1987-08-05
Glaxo Group Ltd
Process

GB9720270D0
(en)

*

1997-09-25
1997-11-26
Pharmagene Lab Limited
Medicaments for the treatment of migraine

GB2330307A
(en)

*

1998-02-07
1999-04-21
Glaxo Group Ltd
EP4 Receptor antagonists as bone resorption inhibitors

US6414006B1
(en)

1998-10-15
2002-07-02
Merck Frosst Canada & Co.
Methods for inhibiting bone resorption

EP1442744B1
(en)

1999-08-10
2006-12-20
Glaxo Group Limited
EP4 receptor ligand and use against neuropathic pain, colon cancer, HIV and migrane

GB0124124D0
(en)

*

2001-10-08
2001-11-28
Medical Res Council
Methods of treatment

WO2003089002A1
(en)

*

2002-04-17
2003-10-30
Medical Research Council
Fp receptor antagonists or pgf2 alpha antagonists for treating menorrhagia

GB0208785D0
(en)

*

2002-04-17
2002-05-29
Medical Res Council
Treatment methtods

WO2004071508A1
(en)

*

2003-02-14
2004-08-26
Medical Research Council
Ip receptor antagonists for the treatment of pathological uterine conditions

EP1924553A1
(en)

2005-08-08
2008-05-28
Argenta Discovery Limited
Bicyclo[2.2.]hept-7-ylamine derivatives and their uses

JP2008193940A
(en)

*

2007-02-13
2008-08-28
Honda Motor Co Ltd
Method for purifying polyhydroxybutyrate

EP3686181A1
(en)

2013-01-30
2020-07-29
Ecolab USA Inc.
Hydrogen sulfide scavengers

US10308886B2
(en)

2015-04-22
2019-06-04
Ecolab Usa Inc.
Development of a novel high temperature stable scavenger for removal of hydrogen sulfide

CA2997083C
(en)

2015-09-08
2023-06-13
Ecolab Usa Inc.
Hydrocarbon soluble/dispersible hemiformals as hydrogen sulfide scavengers

US10584286B2
(en)

2015-09-08
2020-03-10
Ecolab Usa Inc.
Hydrogen sulfide scavengers

US10336950B2
(en)

2016-07-29
2019-07-02
Ecolab Usa Inc.
Antifouling and hydrogen sulfide scavenging compositions and methods

US10538710B2
(en)

2017-07-13
2020-01-21
Ecolab Usa Inc.
Hydrogen sulfide scavengers

WO2020154251A1
(en)

2019-01-23
2020-07-30
Ecolab Usa Inc.
Complete removal of solids during hydrogen sulfide scavenging operations using a scavenger and a michael acceptor

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* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB1553293A
(en)

1976-02-23
1979-09-26
Lepetit Spa
Azaprostaglandins

US4189606A
(en)

*

1976-02-23
1980-02-19
Gruppo Lepetit S.P.A.
13-Azaprostaglandins

ES482357A1
(en)

*

1978-07-11
1980-08-16
Glaxo Group Ltd
Prostanoid compounds and compositions

GB2028805B
(en)

*

1978-07-11
1982-11-03
Glaxo Group Ltd
Prostanoid compounds

US4239778A
(en)

*

1978-09-12
1980-12-16
The University Of Illinois Foundation
Azaprostanoic acid analogs and their use as inhibitors of platelet aggregation

1981

1981-04-28
IL
IL62734A
patent/IL62734A/en
unknown

1981-04-28
JP
JP6353781A
patent/JPS5718671A/en
active
Granted

1981-04-29
US
US06/258,721
patent/US4342756A/en
not_active
Expired – Fee Related

1981-04-29
AU
AU69957/81A
patent/AU540147B2/en
not_active
Ceased

1981-04-29
DK
DK189881A
patent/DK189881A/en
not_active
Application Discontinuation

1981-04-29
FI
FI811350A
patent/FI78293C/en
not_active
IP Right Cessation

1981-04-29
NZ
NZ196966A
patent/NZ196966A/en
unknown

1981-04-29
CH
CH280181A
patent/CH646965A5/en
not_active
IP Right Cessation

1981-04-29
KR
KR1019810001478A
patent/KR850000214B1/en
active
IP Right Grant

1981-04-29
GB
GB8113239A
patent/GB2075503B/en
not_active
Expired

1981-04-29
US
US06/258,737
patent/US4327092A/en
not_active
Expired – Fee Related

1981-04-29
NO
NO811470A
patent/NO811470L/en
unknown

1981-04-29
ES
ES501740A
patent/ES501740A0/en
active
Granted

1981-04-29
IT
IT48367/81A
patent/IT1170929B/en
active

1981-04-29
SE
SE8102731A
patent/SE8102731L/en
not_active
Application Discontinuation

1981-04-29
DE
DE19813117087
patent/DE3117087A1/en
active
Granted

1981-04-29
PT
PT72951A
patent/PT72951B/en
unknown

1981-04-29
AT
AT0191781A
patent/ATA191781A/en
not_active
IP Right Cessation

1981-04-29
NL
NL8102116A
patent/NL8102116A/en
not_active
Application Discontinuation

1981-04-29
IE
IE957/81A
patent/IE51241B1/en
unknown

1981-04-30
FR
FR8108660A
patent/FR2481703B1/en
not_active
Expired

1981-04-30
BE
BE0/204664A
patent/BE888645A/en
not_active
IP Right Cessation

1982

1982-03-26
ES
ES510838A
patent/ES510838A0/en
active
Granted

1982-10-29
JP
JP57190702A
patent/JPS5882723A/en
active
Granted

Also Published As

Publication number
Publication date

GB2075503B
(en)

1984-03-28

NL8102116A
(en)

1981-11-16

US4342756A
(en)

1982-08-03

IE810957L
(en)

1981-10-30

US4327092A
(en)

1982-04-27

IL62734A
(en)

1985-10-31

SE8102731L
(en)

1981-12-21

ES8207498A1
(en)

1982-09-16

DK189881A
(en)

1981-10-31

PT72951A
(en)

1981-05-01

JPH0314028B2
(en)

1991-02-25

FR2481703A1
(en)

1981-11-06

IT1170929B
(en)

1987-06-03

KR850000214B1
(en)

1985-03-06

DE3117087A1
(en)

1982-03-11

IT8148367D0
(en)

1981-04-29

JPS5718671A
(en)

1982-01-30

NZ196966A
(en)

1984-05-31

FI811350L
(en)

1981-10-31

BE888645A
(en)

1981-10-30

PT72951B
(en)

1983-06-15

KR830005187A
(en)

1983-08-03

JPS5882723A
(en)

1983-05-18

IE51241B1
(en)

1986-11-12

JPH0263054B2
(en)

1990-12-27

NO811470L
(en)

1981-11-02

GB2075503A
(en)

1981-11-18

ES501740A0
(en)

1982-09-16

ES8303386A1
(en)

1983-02-01

FI78293B
(en)

1989-03-31

IL62734A0
(en)

1981-06-29

FI78293C
(en)

1989-07-10

AU6995781A
(en)

1981-11-05

ATA191781A
(en)

1985-11-15

ES510838A0
(en)

1983-02-01

FR2481703B1
(en)

1985-08-02

CH646965A5
(en)

1984-12-28

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