AU545467B2

AU545467B2 – Beta-lactamase inhibiting 6-(alkoxyaminomethyl) penicillanic acid 1,1-dioxide and derivatives thereof
– Google Patents

AU545467B2 – Beta-lactamase inhibiting 6-(alkoxyaminomethyl) penicillanic acid 1,1-dioxide and derivatives thereof
– Google Patents
Beta-lactamase inhibiting 6-(alkoxyaminomethyl) penicillanic acid 1,1-dioxide and derivatives thereof

Info

Publication number
AU545467B2

AU545467B2
AU29076/84A
AU2907684A
AU545467B2
AU 545467 B2
AU545467 B2
AU 545467B2
AU 29076/84 A
AU29076/84 A
AU 29076/84A
AU 2907684 A
AU2907684 A
AU 2907684A
AU 545467 B2
AU545467 B2
AU 545467B2
Authority
AU
Australia
Prior art keywords
beta
penicillanic acid
alkoxyaminomethyl
derivatives
dioxide
Prior art date
1983-06-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU29076/84A
Other versions

AU2907684A
(en

Inventor
Edward Fox Kleinman
Donald Klein Pirie
Robert Alfred Volkmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1983-06-06
Filing date
1984-06-05
Publication date
1985-07-18

1984-06-05
Application filed by Pfizer Inc
filed
Critical
Pfizer Inc

1984-12-13
Publication of AU2907684A
publication
Critical
patent/AU2907684A/en

1985-07-18
Application granted
granted
Critical

1985-07-18
Publication of AU545467B2
publication
Critical
patent/AU545467B2/en

2004-06-05
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE

Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS

Y02P20/00—Technologies relating to chemical industry

Y02P20/50—Improvements relating to the production of bulk chemicals

Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

6-alpha/beta-[(C1-C4)Alkoxyaminomethyl and benzyloxyaminomethyl]penicillanic acid 1,1-dioxides, pharmaceutically acceptable salts thereof and conventional esters thereof hydrolyzable under physiological conditions, all of which are useful in medicine as beta-lactamase inhibitors; intermediates and processes therefor; and a process for the conversion of the present compounds to 6-alpha- and 6-beta-(aminomethyl)penicillanic acid 1,1-dioxides and derivatives.

AU29076/84A
1983-06-06
1984-06-05
Beta-lactamase inhibiting 6-(alkoxyaminomethyl) penicillanic acid 1,1-dioxide and derivatives thereof

Ceased

AU545467B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US501475

1983-06-06

US06/501,475

US4499017A
(en)

1983-06-06
1983-06-06
Beta-lactamase inhibiting 6-(alkoxyamino-methyl) penicillanic acid 1,1-dioxide and derivatives

Publications (2)

Publication Number
Publication Date

AU2907684A

AU2907684A
(en)

1984-12-13

AU545467B2
true

AU545467B2
(en)

1985-07-18

Family
ID=23993709
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU29076/84A
Ceased

AU545467B2
(en)

1983-06-06
1984-06-05
Beta-lactamase inhibiting 6-(alkoxyaminomethyl) penicillanic acid 1,1-dioxide and derivatives thereof

Country Status (21)

Country
Link

US
(1)

US4499017A
(en)

EP
(1)

EP0128037B1
(en)

JP
(1)

JPS606693A
(en)

KR
(1)

KR870000312B1
(en)

AT
(1)

ATE24512T1
(en)

AU
(1)

AU545467B2
(en)

CA
(1)

CA1247597A
(en)

DE
(1)

DE3461800D1
(en)

DK
(1)

DK275884A
(en)

ES
(1)

ES8506720A1
(en)

FI
(1)

FI842255A
(en)

GR
(1)

GR82214B
(en)

HU
(1)

HU193573B
(en)

IL
(1)

IL72003A
(en)

NO
(1)

NO842248L
(en)

NZ
(1)

NZ208381A
(en)

PH
(2)

PH21372A
(en)

PL
(1)

PL144040B1
(en)

PT
(1)

PT78689A
(en)

YU
(1)

YU97084A
(en)

ZA
(1)

ZA844184B
(en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB8928373D0
(en)

*

1989-12-15
1990-02-21
Erba Carlo Spa
Beta-lactam derivatives

DK1313714T3
(en)

2000-07-19
2008-12-15
Novartis Ag

Valsartan salts

Family Cites Families (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4234579A
(en)

*

1977-06-07
1980-11-18
Pfizer Inc.
Penicillanic acid 1,1-dioxides as β-lactamase inhibitors

DE2927004A1
(en)

*

1979-07-04
1981-05-27
Bayer Ag, 5090 Leverkusen

PENICILLANIC ACID 1,1-DIOXIDES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS AS MEDICINAL PRODUCTS

US4287181A
(en)

*

1979-10-22
1981-09-01
Pfizer Inc.
Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors

RO84910B
(en)

*

1982-01-11
1984-09-30
Pfizer Inc.
Process for the preparation of 6-amino-alkylpenicillanic acid 1,1-dioxide derivatives

1983

1983-06-06
US
US06/501,475
patent/US4499017A/en
not_active
Expired – Lifetime

1984

1984-06-04
CA
CA000455812A
patent/CA1247597A/en
not_active
Expired

1984-06-04
DE
DE8484303734T
patent/DE3461800D1/en
not_active
Expired

1984-06-04
PL
PL1984248043A
patent/PL144040B1/en
unknown

1984-06-04
DK
DK275884A
patent/DK275884A/en
not_active
Application Discontinuation

1984-06-04
IL
IL72003A
patent/IL72003A/en
not_active
IP Right Cessation

1984-06-04
GR
GR74907A
patent/GR82214B/el
unknown

1984-06-04
AT
AT84303734T
patent/ATE24512T1/en
not_active
IP Right Cessation

1984-06-04
EP
EP84303734A
patent/EP0128037B1/en
not_active
Expired

1984-06-04
PT
PT78689A
patent/PT78689A/en
unknown

1984-06-05
JP
JP59115361A
patent/JPS606693A/en
active
Pending

1984-06-05
YU
YU00970/84A
patent/YU97084A/en
unknown

1984-06-05
FI
FI842255A
patent/FI842255A/en
not_active
Application Discontinuation

1984-06-05
AU
AU29076/84A
patent/AU545467B2/en
not_active
Ceased

1984-06-05
HU
HU842178A
patent/HU193573B/en
unknown

1984-06-05
NZ
NZ208381A
patent/NZ208381A/en
unknown

1984-06-05
KR
KR1019840003122A
patent/KR870000312B1/en
not_active
IP Right Cessation

1984-06-05
ES
ES533147A
patent/ES8506720A1/en
not_active
Expired

1984-06-05
ZA
ZA844184A
patent/ZA844184B/en
unknown

1984-06-05
NO
NO842248A
patent/NO842248L/en
unknown

1984-06-06
PH
PH30780A
patent/PH21372A/en
unknown

1986

1986-03-13
PH
PH33521A
patent/PH22842A/en
unknown

Also Published As

Publication number
Publication date

US4499017A
(en)

1985-02-12

HU193573B
(en)

1987-10-28

ZA844184B
(en)

1986-01-29

YU97084A
(en)

1986-10-31

DK275884D0
(en)

1984-06-04

PL248043A1
(en)

1985-07-30

GR82214B
(en)

1984-12-13

FI842255A0
(en)

1984-06-05

KR870000312B1
(en)

1987-02-26

EP0128037A1
(en)

1984-12-12

DK275884A
(en)

1985-01-09

KR850000446A
(en)

1985-02-27

IL72003A
(en)

1988-02-29

ATE24512T1
(en)

1987-01-15

NO842248L
(en)

1984-12-07

PH21372A
(en)

1987-10-15

NZ208381A
(en)

1987-05-29

ES533147A0
(en)

1985-08-01

CA1247597A
(en)

1988-12-28

FI842255A
(en)

1984-12-07

EP0128037B1
(en)

1986-12-30

DE3461800D1
(en)

1987-02-05

AU2907684A
(en)

1984-12-13

IL72003A0
(en)

1984-10-31

PT78689A
(en)

1984-07-01

ES8506720A1
(en)

1985-08-01

PL144040B1
(en)

1988-04-30

HUT35266A
(en)

1985-06-28

PH22842A
(en)

1989-01-19

JPS606693A
(en)

1985-01-14

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