AU570973B2 - Creación de Inventos y Patentes con Inteligencia Artificial

AU570973B2 – Aminothiazolyl(oxyimino) cephalosporins
– Google Patents

AU570973B2 – Aminothiazolyl(oxyimino) cephalosporins
– Google Patents
Aminothiazolyl(oxyimino) cephalosporins

Info

Publication number
AU570973B2

AU570973B2
AU28582/84A
AU2858284A
AU570973B2
AU 570973 B2
AU570973 B2
AU 570973B2
AU 28582/84 A
AU28582/84 A
AU 28582/84A
AU 2858284 A
AU2858284 A
AU 2858284A
AU 570973 B2
AU570973 B2
AU 570973B2
Authority
AU
Australia
Prior art keywords
alkaline
group
aminothiazolyl
oxyimino
cephalosporins
Prior art date
1983-05-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU28582/84A
Other versions

AU2858284A
(en

Inventor
Dominique Olliero
Ali Salhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi SA

Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1983-05-27
Filing date
1984-05-24
Publication date
1988-03-31

1984-05-24
Application filed by Sanofi SA
filed
Critical
Sanofi SA

1984-11-29
Publication of AU2858284A
publication
Critical
patent/AU2858284A/en

1988-03-31
Application granted
granted
Critical

1988-03-31
Publication of AU570973B2
publication
Critical
patent/AU570973B2/en

2004-05-24
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

C07D501/14—Compounds having a nitrogen atom directly attached in position 7

C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

C07D501/36—Methylene radicals, substituted by sulfur atoms

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D501/14—Compounds having a nitrogen atom directly attached in position 7

C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Abstract

The compounds according to the invention correspond to the formula: (I) in which: The COOA group at the 4 position is an acid radical, or an alkaline or alkaline-earth salt, or an amino acid or amine salt, for example triethylamine or ethanolamines, or an easily hydrolyzable or metabolically labile and pharmaceutically acceptable ester radical. X denotes an oxygen atom or a sulfur atom n is zero or 1 R1 and R2 each denote independently hydrogen or a lower alkyl group, preferably a methyl group, or R1 and R2 taken together with the carbon atom to which they are linked form a cyclobutyl or cyclopentyl nucleus. B is the residue of a primary or secondary amine.

AU28582/84A
1983-05-27
1984-05-24
Aminothiazolyl(oxyimino) cephalosporins

Ceased

AU570973B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

FR8308862A

FR2546520B1
(en)

1983-05-27
1983-05-27

NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS

FR8308862

1983-05-27

Publications (2)

Publication Number
Publication Date

AU2858284A

AU2858284A
(en)

1984-11-29

AU570973B2
true

AU570973B2
(en)

1988-03-31

Family
ID=9289271
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU28582/84A
Ceased

AU570973B2
(en)

1983-05-27
1984-05-24
Aminothiazolyl(oxyimino) cephalosporins

Country Status (27)

Country
Link

US
(1)

US4656166A
(en)

EP
(1)

EP0127543B1
(en)

JP
(1)

JPS59227886A
(en)

KR
(1)

KR910004302B1
(en)

AT
(1)

ATE46339T1
(en)

AU
(1)

AU570973B2
(en)

CA
(1)

CA1247596A
(en)

CS
(1)

CS241546B2
(en)

DD
(1)

DD219773A5
(en)

DE
(1)

DE3479733D1
(en)

DK
(1)

DK255684A
(en)

ES
(1)

ES532805A0
(en)

FI
(1)

FI842042A
(en)

FR
(1)

FR2546520B1
(en)

GR
(1)

GR82042B
(en)

HU
(1)

HU191658B
(en)

IL
(1)

IL71933A
(en)

MA
(1)

MA20126A1
(en)

NO
(1)

NO163408C
(en)

NZ
(1)

NZ208275A
(en)

OA
(1)

OA07777A
(en)

PH
(1)

PH20389A
(en)

PL
(1)

PL144003B1
(en)

PT
(1)

PT78635B
(en)

SU
(1)

SU1282817A3
(en)

YU
(1)

YU90684A
(en)

ZA
(1)

ZA843995B
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU573034B2
(en)

1984-09-27
1988-05-26
Sanofi
Thiazolyl linked cephalosporin derivatives

Families Citing this family (11)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2546520B1
(en)

1983-05-27
1985-08-30
Sanofi Sa

NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS

JPS61207822A
(en)

1985-03-12
1986-09-16
Toyota Motor Corp
Control of suction control valve of variable suction pipe length type suction apparatus

US4783443A
(en)

1986-03-03
1988-11-08
The University Of Chicago
Amino acyl cephalosporin derivatives

US5147871A
(en)

1986-07-03
1992-09-15
Hoffmann La-Roche, Inc.
Anti-bacterial cephalosporin compounds

FR2621589B1
(en)

1987-10-08
1990-03-02
Sanofi Sa

CEPHALOSPORIN DERIVATIVES WITH IMPROVED PHARMACOKINETICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

FR2607135B1
(en)

1986-11-20
1989-04-28
Sanofi Sa

NOVEL CEPHALOSPORINS DERIVATIVES WITH IMPROVED PHARMACOKINETICS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

US5189157A
(en)

1987-06-16
1993-02-23
Hoffmann La Roche Inc.
Antibacterial cephalosporin compounds

CS273349B2
(en)

1988-03-31
1991-03-12
Hoffmann La Roche
Method of cephalosporin’s new derivatives production

US5336768A
(en)

1988-05-24
1994-08-09
Hoffmann-La Roche Inc.
Antibacterial cephalosporin compounds

DE10134478B4
(en)

2001-07-16
2007-10-31
Priaton Gmbh

Process for the preparation of thiazole-substituted β-lactams

FR2842523A1
(en)

2002-07-17
2004-01-23
Sanofi Synthelabo

ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Citations (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU8106182A
(en)

1981-03-03
1982-09-09

Societe Anonyme Dite: Sanofi

Cephalosporin derivatives

Family Cites Families (15)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4338438A
(en)

1970-06-16
1982-07-06
Merck & Co., Inc.
Cephalosporin antibiotics

BE768844A
(en)

1971-06-22
1971-12-22
Fujisawa Pharmaceutical Co
7-(2-acyloxy-acetamido)-3-cephem-4-carboxylic acid derivs – – antibacterials

GB1425933A
(en)

1972-03-13
1976-02-25
Astra Laekemedel Ab
Cephalosporins

OA05033A
(en)

1974-07-01
1980-12-31
Rhone Poulenc Ind

New cephalosporin derivatives and their preparation.

FR2342733A1
(en)

1976-01-14
1977-09-30
Roussel Uclaf

7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS

DE2760123C2
(en)

1976-01-23
1986-04-30
Roussel-Uclaf, Paris

7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporanic acids, their preparation and pharmaceutical compositions containing them

GR63088B
(en)

1976-04-14
1979-08-09
Takeda Chemical Industries Ltd
Preparation process of novel cephalosporins

DE2716677C2
(en)

1977-04-15
1985-10-10
Hoechst Ag, 6230 Frankfurt

Cephem derivatives and processes for their preparation

US4341775A
(en)

1978-09-11
1982-07-27
Fujisawa Pharmaceutical Co., Ltd.
Cephem compounds

US4409215A
(en)

1979-11-19
1983-10-11
Fujisawa Pharmaceutical Co., Ltd.
7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof

FR2485540A1
(en)

1980-06-30
1981-12-31
Sanofi Sa
Cephalosporin(s) active against gram-negative bacteria – are 7- 2-2-amino-4-thiazolyl 2-methoxy-imino acetamido 3 hydroxy-1,2,4-triazinyl-thiomethyl 3-cephem 4-carboxylic acid 1-S-oxide(s)

EP0055465B1
(en)

1980-12-31
1989-08-23
Fujisawa Pharmaceutical Co., Ltd.
7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof

FR2506307A1
(en)

1981-05-22
1982-11-26
Roussel Uclaf
7-thiazolyl-acetamido-cephalosporin oxime derivs. – useful as broad spectrum antibacterials and disinfectants (BE 1.10.79)

US4396619A
(en)

1981-09-08
1983-08-02
Eli Lilly And Company
Cephalosporin betaines

FR2546520B1
(en)

1983-05-27
1985-08-30
Sanofi Sa

NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS

1983

1983-05-27
FR
FR8308862A
patent/FR2546520B1/en
not_active
Expired

1984

1984-05-22
FI
FI842042A
patent/FI842042A/en
not_active
Application Discontinuation

1984-05-22
CA
CA000454824A
patent/CA1247596A/en
not_active
Expired

1984-05-22
US
US06/612,896
patent/US4656166A/en
not_active
Ceased

1984-05-24
PH
PH30714A
patent/PH20389A/en
unknown

1984-05-24
DK
DK255684A
patent/DK255684A/en
not_active
Application Discontinuation

1984-05-24
DD
DD84263344A
patent/DD219773A5/en
not_active
IP Right Cessation

1984-05-24
AU
AU28582/84A
patent/AU570973B2/en
not_active
Ceased

1984-05-24
PT
PT78635A
patent/PT78635B/en
not_active
IP Right Cessation

1984-05-24
GR
GR74812A
patent/GR82042B/el
unknown

1984-05-25
DE
DE8484401080T
patent/DE3479733D1/en
not_active
Expired

1984-05-25
SU
SU843749939A
patent/SU1282817A3/en
active

1984-05-25
HU
HU842045A
patent/HU191658B/en
not_active
IP Right Cessation

1984-05-25
IL
IL71933A
patent/IL71933A/en
unknown

1984-05-25
EP
EP84401080A
patent/EP0127543B1/en
not_active
Expired

1984-05-25
OA
OA58304A
patent/OA07777A/en
unknown

1984-05-25
NZ
NZ208275A
patent/NZ208275A/en
unknown

1984-05-25
ES
ES532805A
patent/ES532805A0/en
active
Granted

1984-05-25
YU
YU00906/84A
patent/YU90684A/en
unknown

1984-05-25
ZA
ZA843995A
patent/ZA843995B/en
unknown

1984-05-25
NO
NO842091A
patent/NO163408C/en
unknown

1984-05-25
MA
MA20348A
patent/MA20126A1/en
unknown

1984-05-25
AT
AT84401080T
patent/ATE46339T1/en
not_active
IP Right Cessation

1984-05-25
PL
PL1984247843A
patent/PL144003B1/en
unknown

1984-05-26
KR
KR1019840002913A
patent/KR910004302B1/en
active
IP Right Grant

1984-05-28
JP
JP59108253A
patent/JPS59227886A/en
active
Pending

1984-05-28
CS
CS843997A
patent/CS241546B2/en
unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU8106182A
(en)

1981-03-03
1982-09-09
Societe Anonyme Dite: Sanofi
Cephalosporin derivatives

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU573034B2
(en)

1984-09-27
1988-05-26
Sanofi
Thiazolyl linked cephalosporin derivatives

Also Published As

Publication number
Publication date

CS399784A2
(en)

1985-07-16

DK255684D0
(en)

1984-05-24

PH20389A
(en)

1986-12-10

NO842091L
(en)

1984-11-28

NZ208275A
(en)

1986-11-12

KR910004302B1
(en)

1991-06-25

US4656166A
(en)

1987-04-07

PL144003B1
(en)

1988-04-30

CA1247596A
(en)

1988-12-28

FR2546520A1
(en)

1984-11-30

DD219773A5
(en)

1985-03-13

YU90684A
(en)

1986-12-31

DE3479733D1
(en)

1989-10-19

FR2546520B1
(en)

1985-08-30

CS241546B2
(en)

1986-03-13

PL247843A1
(en)

1985-03-26

NO163408B
(en)

1990-02-12

ZA843995B
(en)

1984-12-24

MA20126A1
(en)

1984-12-31

PT78635A
(en)

1984-06-01

EP0127543B1
(en)

1989-09-13

JPS59227886A
(en)

1984-12-21

HU191658B
(en)

1987-03-30

IL71933A
(en)

1987-11-30

HUT34500A
(en)

1985-03-28

NO163408C
(en)

1990-05-23

EP0127543A2
(en)

1984-12-05

EP0127543A3
(en)

1985-11-27

FI842042A
(en)

1984-11-28

FI842042A0
(en)

1984-05-22

ES8502706A1
(en)

1985-01-16

KR840009114A
(en)

1984-12-24

DK255684A
(en)

1984-11-28

GR82042B
(en)

1984-12-12

PT78635B
(en)

1986-06-18

OA07777A
(en)

1985-08-30

AU2858284A
(en)

1984-11-29

ATE46339T1
(en)

1989-09-15

IL71933A0
(en)

1984-09-30

SU1282817A3
(en)

1987-01-07

ES532805A0
(en)

1985-01-16

Información de contacto