AU5947180A

AU5947180A – Cephalosporin derivatives
– Google Patents

AU5947180A – Cephalosporin derivatives
– Google Patents
Cephalosporin derivatives

Info

Publication number
AU5947180A

AU5947180A
AU59471/80A
AU5947180A
AU5947180A
AU 5947180 A
AU5947180 A
AU 5947180A
AU 59471/80 A
AU59471/80 A
AU 59471/80A
AU 5947180 A
AU5947180 A
AU 5947180A
AU 5947180 A
AU5947180 A
AU 5947180A
Authority
AU
Australia
Prior art keywords
thiadiazol
methyl
hydrogen
thiomorpholino
methoxy
Prior art date
1979-06-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU59471/80A
Other versions

AU536982B2
(en

Inventor
Hans Goeth
Uwe Lechner
Roland Maier
Wolfgang Reuter
Bernd Wetzel
Eberhard Woitun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1979-06-21
Filing date
1980-06-20
Publication date
1981-01-08

1980-06-20
Application filed by Dr Karl Thomae GmbH
filed
Critical
Dr Karl Thomae GmbH

1981-01-08
Publication of AU5947180A
publication
Critical
patent/AU5947180A/en

1984-05-31
Application granted
granted
Critical

1984-05-31
Publication of AU536982B2
publication
Critical
patent/AU536982B2/en

2000-06-20
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings

C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members

C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

C07D239/46—Two or more oxygen, sulphur or nitrogen atoms

C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE

Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS

Y02P20/00—Technologies relating to chemical industry

Y02P20/50—Improvements relating to the production of bulk chemicals

Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Cephalosporins of the formula wherein A is phenyl, 4-hydroxyphenyl, cyclohexyl, cyclohexene-1-yl, cyclohexa-1,4-diene-1-yl, 2-thienyl, 3-thienyl, 2-furyl, 3-furyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy; Y is hydrogen or methoxy; D is hydrogen, hydroxyl, acetoxy, aminocarbonyloxy, pyridinium, aminocarbonyl-pyridinium or the group S-Het, where Het is 1-methyl-tetrazol-5-yl, tetrazol-5-yl, 3-methyl-1,2,4-thiadiazol-5-yl,1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 2-methylamino-1,3,4-thiadiazol-5-yl, 2-dimethylamino-1,3,4-thiadiazol-5-yl, 2-formylamino-1,3,4-thiadiazol-5-yl, 2-acetylamino-1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-oxadiazol-5-yl, 1,2,3-triazol-4-yl or 1,2,4-triazol-3-yl; R is hydrogen, methyl, cyclopropyl, hydroxyl, methoxy, ethoxy, mercapto, morpholino, thiomorpholino, thiomorpholino-S-oxide, thiomorpholino-S,S-dioxide, +TR E is hydrogen or a protective group which is easily removable in vitro or in vivo; and non-toxic, pharmacologically acceptable salts thereof.

AU59471/80A
1979-06-21
1980-06-20
Cephalosporin derivatives

Ceased

AU536982B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

DE19792924948

DE2924948A1
(en)

1979-06-21
1979-06-21

NEW CEPHALOSPORINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

DE29249487

1979-06-21

Publications (2)

Publication Number
Publication Date

AU5947180A
true

AU5947180A
(en)

1981-01-08

AU536982B2

AU536982B2
(en)

1984-05-31

Family
ID=6073715
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU59471/80A
Ceased

AU536982B2
(en)

1979-06-21
1980-06-20
Cephalosporin derivatives

Country Status (19)

Country
Link

US
(2)

US4316898A
(en)

EP
(1)

EP0021176B1
(en)

JP
(1)

JPS567791A
(en)

AT
(1)

ATE5886T1
(en)

AU
(1)

AU536982B2
(en)

CA
(1)

CA1146537A
(en)

DE
(2)

DE2924948A1
(en)

DK
(1)

DK261780A
(en)

ES
(4)

ES491775A0
(en)

FI
(1)

FI68840C
(en)

GR
(1)

GR68107B
(en)

HU
(1)

HU184793B
(en)

IE
(1)

IE49922B1
(en)

IL
(1)

IL60366A
(en)

NO
(1)

NO801848L
(en)

NZ
(1)

NZ194103A
(en)

PH
(1)

PH17717A
(en)

PT
(1)

PT71440B
(en)

ZA
(1)

ZA803710B
(en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS5643288A
(en)

*

1979-09-18
1981-04-21
Meiji Seika Kaisha Ltd
Cephalosporin derivative and its preparation

DE3007685A1
(en)

*

1980-02-29
1981-10-01
Dr. Karl Thomae Gmbh, 7950 Biberach

NEW CEPHYLOSPORINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

DE3038501A1
(en)

*

1980-10-11
1982-05-19
Dr. Karl Thomae Gmbh, 7950 Biberach

NEW CEPHALOSPORINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND

EP0053276A3
(en)

*

1980-12-02
1983-08-03
Dr. Karl Thomae GmbH
Cephalosporins, process for their preparation and pharmaceutical compositions containing them

DE3047082A1
(en)

*

1980-12-13
1982-07-29
Dr. Karl Thomae Gmbh, 7950 Biberach

NEW CEPHALOSPORINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

DE3134776A1
(en)

*

1981-09-02
1983-03-10
Dr. Karl Thomae Gmbh, 7950 Biberach

NEW 6 (ALPHA) METHOXY PENICILLINE, ITS SALTS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

CN102675342A
(en)

*

2011-03-15
2012-09-19
四平市精细化学品有限公司
Preparation method of 7 beta-amino-7 alpha-methoxy-3-((1-methyl-1H-tetrazole-5-group) sulfomethyl)-3-cephem-4-diphenylmethyl carboxylate

Family Cites Families (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AR208171A1
(en)

*

1972-09-29
1976-12-09
Ciba Geigy Ag

PROCEDURE FOR OBTAINING NEW DERIVATIVES OF CEF-3-EM-4-CARBOXYL ACID

DE2710979A1
(en)

*

1977-03-14
1978-09-21
Merck Patent Gmbh
Alpha-heterocyclyl-ureido-acetamido penicillin and cephalosporin cpds. – antibacterials for human and veterinary medicine active esp. against Pseudomonas

DE2650826A1
(en)

*

1976-11-06
1978-05-11
Merck Patent Gmbh
Alpha-heterocyclyl-ureido-acetamido penicillin and cephalosporin cpds. – antibacterials for human and veterinary medicine active esp. against Pseudomonas

DE2828261A1
(en)

*

1978-06-28
1980-01-10
Thomae Gmbh Dr K

NEW PENICILLINE, ITS SALTS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

1979

1979-06-21
DE
DE19792924948
patent/DE2924948A1/en
not_active
Withdrawn

1980

1980-04-28
GR
GR61798A
patent/GR68107B/el
unknown

1980-05-20
US
US06/151,694
patent/US4316898A/en
not_active
Expired – Lifetime

1980-05-23
ES
ES491775A
patent/ES491775A0/en
active
Granted

1980-06-06
EP
EP80103135A
patent/EP0021176B1/en
not_active
Expired

1980-06-06
AT
AT80103135T
patent/ATE5886T1/en
active

1980-06-06
DE
DE8080103135T
patent/DE3066148D1/en
not_active
Expired

1980-06-11
JP
JP7887580A
patent/JPS567791A/en
active
Pending

1980-06-17
PH
PH24152A
patent/PH17717A/en
unknown

1980-06-17
CA
CA000354162A
patent/CA1146537A/en
not_active
Expired

1980-06-19
FI
FI801979A
patent/FI68840C/en
not_active
IP Right Cessation

1980-06-19
DK
DK261780A
patent/DK261780A/en
not_active
Application Discontinuation

1980-06-20
AU
AU59471/80A
patent/AU536982B2/en
not_active
Ceased

1980-06-20
IE
IE1289/80A
patent/IE49922B1/en
unknown

1980-06-20
NZ
NZ194103A
patent/NZ194103A/en
unknown

1980-06-20
ZA
ZA00803710A
patent/ZA803710B/en
unknown

1980-06-20
PT
PT71440A
patent/PT71440B/en
unknown

1980-06-20
IL
IL60366A
patent/IL60366A/en
unknown

1980-06-20
NO
NO801848A
patent/NO801848L/en
unknown

1980-06-20
HU
HU801544A
patent/HU184793B/en
unknown

1981

1981-01-15
ES
ES498522A
patent/ES8200692A1/en
not_active
Expired

1981-01-15
ES
ES498520A
patent/ES498520A0/en
active
Granted

1981-01-15
ES
ES498521A
patent/ES498521A0/en
active
Granted

1981-09-30
US
US06/307,117
patent/US4388315A/en
not_active
Expired – Fee Related

Also Published As

Publication number
Publication date

US4388315A
(en)

1983-06-14

GR68107B
(en)

1981-10-30

ES498522A0
(en)

1981-11-01

FI68840B
(en)

1985-07-31

PT71440A
(en)

1980-07-01

ES8200690A1
(en)

1981-11-01

FI68840C
(en)

1985-11-11

ES8200692A1
(en)

1981-11-01

ES8200691A1
(en)

1981-11-01

NZ194103A
(en)

1984-07-06

US4316898A
(en)

1982-02-23

IL60366A0
(en)

1980-09-16

ES498521A0
(en)

1981-11-01

DE3066148D1
(en)

1984-02-23

DE2924948A1
(en)

1981-01-22

EP0021176B1
(en)

1984-01-18

IE801289L
(en)

1980-12-21

AU536982B2
(en)

1984-05-31

HU184793B
(en)

1984-10-29

ES498520A0
(en)

1981-11-01

ES8200370A1
(en)

1981-10-16

ZA803710B
(en)

1982-02-24

PH17717A
(en)

1984-11-21

EP0021176A2
(en)

1981-01-07

IE49922B1
(en)

1986-01-08

JPS567791A
(en)

1981-01-27

NO801848L
(en)

1980-12-22

IL60366A
(en)

1984-02-29

PT71440B
(en)

1981-10-23

ES491775A0
(en)

1981-10-16

FI801979A
(en)

1980-12-22

CA1146537A
(en)

1983-05-17

DK261780A
(en)

1980-12-22

ATE5886T1
(en)

1984-02-15

EP0021176A3
(en)

1981-12-23

Similar Documents

Publication
Publication Date
Title

AU536982B2
(en)

1984-05-31

Cephalosporin derivatives

AU539009B2
(en)

1984-09-06

Chemical compounds

AU536912B2
(en)

1984-05-31

Benzothiazole derivatives

EP0209751A2
(en)

1987-01-28

Cephalosporin derivatives and bactericides containing the same

KR900006346A
(en)

1990-05-08

3-aryloxymethyl-cephalosporin derivatives, their preparation and their medical use

IL57795A
(en)

1982-09-30

Lower alkanoyloxyalkyl esters and-2)ethers of 7-(2(2-furyl)-2-(alkoxyimino)-acetamido)-cephalosporin compounds,their preparation and pharmaceutical compositions containing them

US3898220A
(en)

1975-08-05

Trifluoromethylmercaptoacetamidocephalosporins

ES8304996A1
(en)

1983-03-16

Cephalosporins, process for their preparation and pharmaceutical compositions containing them.

JPS60190783A
(en)

1985-09-28

Cephem compound

ES8304575A1
(en)

1983-03-01

Cephalosporins, process for their preparation and pharmaceutical compositions containing them.

Download PDF in English