AU6427786A

AU6427786A – Novel quinoline derivatives and processes for preparation thereof
– Google Patents

AU6427786A – Novel quinoline derivatives and processes for preparation thereof
– Google Patents
Novel quinoline derivatives and processes for preparation thereof

Info

Publication number
AU6427786A

AU6427786A
AU64277/86A
AU6427786A
AU6427786A
AU 6427786 A
AU6427786 A
AU 6427786A
AU 64277/86 A
AU64277/86 A
AU 64277/86A
AU 6427786 A
AU6427786 A
AU 6427786A
AU 6427786 A
AU6427786 A
AU 6427786A
Authority
AU
Australia
Prior art keywords
processes
preparation
quinoline derivatives
novel quinoline
novel
Prior art date
1985-10-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU64277/86A
Other versions

AU594983B2
(en

Inventor
Hiroshi Egawa
Junichi Matsumoto
Teruyuki Miyamoto
Shinichi Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dainippon Pharmaceutical Co Ltd

Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-10-29
Filing date
1986-10-22
Publication date
1987-04-30

1986-10-22
Application filed by Dainippon Pharmaceutical Co Ltd
filed
Critical
Dainippon Pharmaceutical Co Ltd

1987-04-30
Publication of AU6427786A
publication
Critical
patent/AU6427786A/en

1990-03-22
Application granted
granted
Critical

1990-03-22
Publication of AU594983B2
publication
Critical
patent/AU594983B2/en

2006-10-22
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings

C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom

C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3

C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

AU64277/86A
1985-10-29
1986-10-22
Novel quinoline derivatives and processes for preparation thereof

Expired

AU594983B2
(en)

Applications Claiming Priority (6)

Application Number
Priority Date
Filing Date
Title

JP60-242257

1985-10-29

JP24225785

1985-10-29

JP60-285323

1985-12-17

JP28532385

1985-12-17

JP3262786

1986-02-17

JP61-32627

1986-02-17

Publications (2)

Publication Number
Publication Date

AU6427786A
true

AU6427786A
(en)

1987-04-30

AU594983B2

AU594983B2
(en)

1990-03-22

Family
ID=27287785
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU64277/86A
Expired

AU594983B2
(en)

1985-10-29
1986-10-22
Novel quinoline derivatives and processes for preparation thereof

Country Status (26)

Country
Link

US
(1)

US4795751A
(en)

EP
(2)

EP0221463B1
(en)

JP
(2)

JPS62277362A
(en)

KR
(1)

KR910006806B1
(en)

CN
(1)

CN1009930B
(en)

AR
(3)

AR242031A1
(en)

AT
(2)

ATE109472T1
(en)

AU
(1)

AU594983B2
(en)

CA
(1)

CA1340402C
(en)

DE
(3)

DE3680859D1
(en)

DK
(2)

DK170593B1
(en)

ES
(2)

ES2057197T3
(en)

FI
(1)

FI87457C
(en)

GE
(1)

GEP19960467B
(en)

GR
(1)

GR3002475T3
(en)

HU
(1)

HU200452B
(en)

IL
(1)

IL80404A
(en)

LU
(2)

LU88596I2
(en)

MY
(1)

MY100574A
(en)

NL
(2)

NL970020I2
(en)

NO
(1)

NO170726C
(en)

NZ
(1)

NZ218089A
(en)

PH
(1)

PH22862A
(en)

PT
(1)

PT83643B
(en)

SU
(2)

SU1598873A3
(en)

YU
(3)

YU46414B
(en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4977154A
(en)

*

1985-12-12
1990-12-11
Warner-Lambert Company
5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents

EP0242789A3
(en)

*

1986-04-25
1990-09-05
Dainippon Pharmaceutical Co., Ltd.
Novel quinoline derivates and processes for preparation thereof

DE3711193A1
(en)

*

1987-04-02
1988-10-13
Bayer Ag

5-SUBSTITUTED CHINOLON AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES

US5563138A
(en)

*

1987-04-16
1996-10-08
Otsuka Pharmaceutical Company, Limited
Benzoheterocyclic compounds

US4780468A
(en)

*

1987-08-07
1988-10-25
Warner-Lambert Company
8-trifluoromethyl quinolones as antibacterial agents

IL88003A
(en)

*

1987-10-16
1992-11-15
Dainippon Pharmaceutical Co
Quinoline derivatives,their preparation and pharmaceutical compositions containing them

US5164392A
(en)

*

1987-10-16
1992-11-17
Dainippon Pharmaceutical Co., Ltd.
Quinoline derivatives and antibacterial agent containing them

AU609974B2
(en)

*

1988-05-18
1991-05-09
Warner-Lambert Company
Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids

JPH0674261B2
(en)

*

1988-06-21
1994-09-21
塩野義製薬株式会社

Quinolonecarboxylic acid derivative

JP2709604B2
(en)

*

1988-06-29
1998-02-04
大日本製薬株式会社

Prevention or removal of mycoplasma contamination

US5262417A
(en)

*

1988-12-06
1993-11-16
The Upjohn Company
Antibacterial quinolone compounds

FR2655545B1
(en)

1989-12-11
1994-06-10
Rhone Poulenc Sante

NEW THERAPEUTIC APPLICATION OF FLUOROQUINOLONE DERIVATIVES.

DE4019023A1
(en)

*

1990-06-14
1991-12-19
Bayer Ag

METHOD FOR PRODUCING CHINOLINE CARBONIC ACIDS

JP2613139B2
(en)

*

1990-07-19
1997-05-21
エスエス製薬 株式会社

Quinolonecarboxylic acid derivatives

US5342846A
(en)

*

1990-12-05
1994-08-30
Synphar Laboratories, Inc.
7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents

FR2681863B1
(en)

*

1991-09-27
1995-02-03
Rhone Dpc Europ

SOLUTION OF SPARFLOXACIN, ITS PREPARATION AND SALT CONSTITUTING IT.

TW222272B
(en)

*

1992-05-26
1994-04-11
Ss Seiyaku Kk

WO1993025545A1
(en)

*

1992-06-09
1993-12-23
Korea Research Institute Of Chemical Technology
Novel quinoline derivatives and processes for preparing the same

US5290794A
(en)

*

1992-10-27
1994-03-01
Warner Lambert Co.
Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms

US5646163A
(en)

*

1992-10-30
1997-07-08
The Procter & Gamble Company
Quinolone 5-(N-heterosubstituted amino) antimicrobials

CN1038326C
(en)

*

1993-07-20
1998-05-13
爱斯制药株式会社
5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient

US5532239A
(en)

*

1993-08-02
1996-07-02
Assistance Publique – Hopitaux De Paris
Therapeutic application of fluoroquinolone derivatives

WO2000032196A2
(en)

1998-12-04
2000-06-08
Influx, Inc.
Inhibitors of multidrug transporters

RU2270695C2
(en)

1999-03-17
2006-02-27
Дайити Фармасьютикал Ко., Лтд.
Pharmaceutical composition

CN1091103C
(en)

*

1999-04-02
2002-09-18
中国科学院上海药物研究所
Compounds of carbostyrils and their preparation and use

US6957105B2
(en)

*

2002-03-26
2005-10-18
Cardiac Pacemakers, Inc.
Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals

KR100519158B1
(en)

*

2002-12-21
2005-10-06
주식회사유한양행
A process for preparation of quinolone carboxylate derivatives

US7973022B2
(en)

2006-02-17
2011-07-05
Idexx Laboratories, Inc.
Fluoroquinolone carboxylic acid salt compositions

US20070196398A1
(en)

*

2006-02-17
2007-08-23
Murthy Yerramilli V S
Fluoroquinolone fatty acid salt compositions

US20070197548A1
(en)

*

2006-02-17
2007-08-23
Murthy Yerramilli V S
Fluoroquinolone compositions

US20080139574A1
(en)

2006-11-30
2008-06-12
Cadila Healthcare Limited
Novel quinoline derivatives

CN111065385A
(en)

2017-06-22
2020-04-24
希普拉有限公司
Method of treating cancer

CN110724097B
(en)

*

2019-11-11
2021-03-09
山东畜牧兽医职业学院
Compound for treating drug-resistant microbial bacteria and preparation method thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3753993A
(en)

*

1971-05-17
1973-08-21
Sterling Drug Inc
1,4-dihydro-4-oxo-7-pyridyl-3-quinoline-carboxylic acid derivatives

DE3033157A1
(en)

*

1980-09-03
1982-04-01
Bayer Ag, 5090 Leverkusen

7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM

JPS58174367A
(en)

1982-04-07
1983-10-13
Tanabe Seiyaku Co Ltd
Quinoline derivative and its preparation

DE3248507A1
(en)

*

1982-12-29
1984-07-05
Bayer Ag, 5090 Leverkusen

MICROBICIDE AGENTS BASED ON CHINOLONIC CARBONIC ACID

DE3248506A1
(en)

*

1982-12-29
1984-07-05
Bayer Ag, 5090 Leverkusen

1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7 (ALKYL-1-PIPERAZINYL) -3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS

DE3306771A1
(en)

*

1983-02-25
1984-08-30
Bayer Ag, 5090 Leverkusen

CHINOLONIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM

DE3318145A1
(en)

*

1983-05-18
1984-11-22
Bayer Ag, 5090 Leverkusen

7-AMINO-1-CYCLOPROPYL-6,8-DIFLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS

CS274601B2
(en)

*

1983-07-27
1991-09-15
Dainippon Pharmaceutical Co
Method of 1,8-naphthyridine derivative production

JPS60169475A
(en)

*

1984-02-14
1985-09-02
Dai Ichi Seiyaku Co Ltd
Quinoline derivative

DE3574380D1
(en)

*

1984-02-17
1989-12-28
Daiichi Seiyaku Co
1,8-naphthyridine derivatives

US4571396A
(en)

*

1984-04-16
1986-02-18
Warner-Lambert Company
Antibacterial agents

ZA852369B
(en)

1984-04-26
1985-12-24
Abbott Lab
Quinoline antibacterial compounds

DE3420798A1
(en)

*

1984-06-04
1985-12-05
Bayer Ag, 5090 Leverkusen

7- (3-ARYL-L-PIPERAZINYL) – AND 7- (3-CYCLOHEXYL-L-PIPERAZINYL) -3-CHINOLONIC CARBONIC ACIDS

DE3420743A1
(en)

*

1984-06-04
1985-12-05
Bayer Ag, 5090 Leverkusen

7-AMINO-1-CYCLOPROPYL-6,8-DIHALOGEN-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS

JPS6110574A
(en)

*

1984-06-25
1986-01-18
Hokuriku Seiyaku Co Ltd
6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinylquinoline-3-carboxylic acid derivative

IE58742B1
(en)

1984-07-20
1993-11-05
Warner Lambert Co
Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds

JPS6191183A
(en)

*

1984-10-11
1986-05-09
Kyorin Pharmaceut Co Ltd
Quinolonecarboxylic acid derivative

EP0181521A1
(en)

*

1984-10-19
1986-05-21
Otsuka Pharmaceutical Co., Ltd.
Antimicrobial 1-substituted Phenyl-4-oxoquinoline-3-carboxylic acid compounds

US4636506A
(en)

*

1984-12-06
1987-01-13
Pfizer, Inc.
7-heterocyclic-1,4-dihydroquinolones

DE3576335D1
(en)

*

1984-12-14
1990-04-12
Daiichi Seiyaku Co

CHINOLINE CARBONIC ACID DERIVATIVES.

US4657913A
(en)

*

1985-04-18
1987-04-14
Warner-Lambert Company
Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents

JPS6259263A
(en)

*

1985-09-10
1987-03-14
Kyorin Pharmaceut Co Ltd
Quinolonecarboxylic acid derivative

US4668680A
(en)

*

1985-12-12
1987-05-26
Warner-Lambert Company
5-amino-6,8-difluoroquinolones as antibacterial agents

US4977154A
(en)

*

1985-12-12
1990-12-11
Warner-Lambert Company
5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents

EP0230053A3
(en)

*

1986-01-17
1988-03-30
American Cyanamid Company
7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

EP0242789A3
(en)

*

1986-04-25
1990-09-05
Dainippon Pharmaceutical Co., Ltd.
Novel quinoline derivates and processes for preparation thereof

GB8612137D0
(en)

*

1986-05-19
1986-06-25
Fujisawa Pharmaceutical Co
Quinolone compounds

1986

1986-10-22
AU
AU64277/86A
patent/AU594983B2/en
not_active
Expired

1986-10-23
DE
DE8686114748T
patent/DE3680859D1/en
not_active
Expired – Fee Related

1986-10-23
DE
DE3650018T
patent/DE3650018T2/en
not_active
Expired – Lifetime

1986-10-23
IL
IL80404A
patent/IL80404A/en
not_active
IP Right Cessation

1986-10-23
AT
AT90101210T
patent/ATE109472T1/en
active

1986-10-23
AT
AT86114748T
patent/ATE66210T1/en
not_active
IP Right Cessation

1986-10-23
FI
FI864299A
patent/FI87457C/en
not_active
IP Right Cessation

1986-10-23
DE
DE2000175028
patent/DE10075028I2/en
active
Active

1986-10-23
EP
EP86114748A
patent/EP0221463B1/en
not_active
Expired – Lifetime

1986-10-23
NO
NO864247A
patent/NO170726C/en
not_active
IP Right Cessation

1986-10-23
EP
EP90101210A
patent/EP0375658B1/en
not_active
Expired – Lifetime

1986-10-23
LU
LU88596C
patent/LU88596I2/en
unknown

1986-10-23
ES
ES90101210T
patent/ES2057197T3/en
not_active
Expired – Lifetime

1986-10-23
ES
ES198686114748T
patent/ES2029786T3/en
not_active
Expired – Lifetime

1986-10-24
HU
HU864479A
patent/HU200452B/en
unknown

1986-10-28
CA
CA000521561A
patent/CA1340402C/en
not_active
Expired – Lifetime

1986-10-28
DK
DK514586A
patent/DK170593B1/en
not_active
IP Right Cessation

1986-10-28
MY
MYPI86000045A
patent/MY100574A/en
unknown

1986-10-28
NZ
NZ218089A
patent/NZ218089A/en
unknown

1986-10-28
JP
JP61257175A
patent/JPS62277362A/en
active
Granted

1986-10-28
US
US06/928,297
patent/US4795751A/en
not_active
Expired – Lifetime

1986-10-29
CN
CN86107491A
patent/CN1009930B/en
not_active
Expired

1986-10-29
PT
PT83643A
patent/PT83643B/en
unknown

1986-10-29
AR
AR86305742A
patent/AR242031A1/en
active

1986-10-29
PH
PH34426A
patent/PH22862A/en
unknown

1986-10-29
KR
KR1019860009083A
patent/KR910006806B1/en
not_active
IP Right Cessation

1986-10-29
YU
YU183586A
patent/YU46414B/en
unknown

1987

1987-10-27
SU
SU874203548A
patent/SU1598873A3/en
active

1987-10-27
SU
SU874203544A
patent/SU1635898A3/en
active

1990

1990-11-19
AR
AR90318409A
patent/AR243178A1/en
active

1990-11-19
AR
AR90318410A
patent/AR243520A1/en
active

1991

1991-08-08
YU
YU137191A
patent/YU137191A/en
unknown

1991-08-08
YU
YU137291A
patent/YU137291A/en
unknown

1991-08-16
GR
GR91401047T
patent/GR3002475T3/en
unknown

1991-12-26
JP
JP35979491A
patent/JPH0714918B2/en
not_active
Expired – Lifetime

1992

1992-02-28
DK
DK025992A
patent/DK170774B1/en
not_active
IP Right Cessation

1993

1993-07-29
GE
GEAP19931276A
patent/GEP19960467B/en
unknown

1997

1997-05-30
NL
NL970020C
patent/NL970020I2/en
unknown

2000

2000-08-08
NL
NL300014C
patent/NL300014I2/en
unknown

2000-08-09
LU
LU90621C
patent/LU90621I2/en
unknown

Also Published As

Publication number
Publication date

JPH0543551A
(en)

1993-02-23

DK25992D0
(en)

1992-02-28

DK25992A
(en)

1992-02-28

DK514586D0
(en)

1986-10-28

FI864299A0
(en)

1986-10-23

DE10075028I2
(en)

2004-01-29

CN1009930B
(en)

1990-10-10

AR243178A1
(en)

1993-07-30

GR3002475T3
(en)

1992-12-30

YU46414B
(en)

1993-10-20

US4795751A
(en)

1989-01-03

NZ218089A
(en)

1989-03-29

JPH0714918B2
(en)

1995-02-22

CN86107491A
(en)

1987-04-29

AU594983B2
(en)

1990-03-22

ES2029786T3
(en)

1992-10-01

NL300014I1
(en)

2000-10-02

YU183586A
(en)

1988-04-30

NO864247L
(en)

1987-04-30

HUT43839A
(en)

1987-12-28

DK514586A
(en)

1987-04-30

LU88596I2
(en)

1995-07-10

GEP19960467B
(en)

1996-05-27

YU137291A
(en)

1994-01-20

MY100574A
(en)

1990-12-15

AR242031A1
(en)

1993-02-26

NO170726C
(en)

1992-11-25

FI87457B
(en)

1992-09-30

DK170774B1
(en)

1996-01-15

AR243520A1
(en)

1993-08-31

NL970020I2
(en)

1998-01-05

IL80404A
(en)

1990-06-10

KR870004019A
(en)

1987-05-06

JPS62277362A
(en)

1987-12-02

SU1635898A3
(en)

1991-03-15

PT83643B
(en)

1988-10-14

PT83643A
(en)

1986-11-01

FI87457C
(en)

1993-01-11

JPH0541633B2
(en)

1993-06-24

PH22862A
(en)

1989-01-19

NO170726B
(en)

1992-08-17

LU90621I2
(en)

2000-10-09

DK170593B1
(en)

1995-11-06

ATE109472T1
(en)

1994-08-15

DE3650018T2
(en)

1995-01-05

NO864247D0
(en)

1986-10-23

EP0375658B1
(en)

1994-08-03

IL80404A0
(en)

1987-01-30

ATE66210T1
(en)

1991-08-15

NL300014I2
(en)

2001-02-01

DE3680859D1
(en)

1991-09-19

HU200452B
(en)

1990-06-28

CA1340402C
(en)

1999-02-23

EP0375658A1
(en)

1990-06-27

EP0221463A3
(en)

1987-12-02

SU1598873A3
(en)

1990-10-07

YU137191A
(en)

1994-01-20

KR910006806B1
(en)

1991-09-02

DE3650018D1
(en)

1994-09-08

FI864299A
(en)

1987-04-30

EP0221463A2
(en)

1987-05-13

ES2057197T3
(en)

1994-10-16

EP0221463B1
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1991-08-14

DE10075028I1
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2000-12-14

NL970020I1
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1997-08-01

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