AU7567787A – Taxol derivatives, their preparation and pharmaceutical compositions containing them
– Google Patents
AU7567787A – Taxol derivatives, their preparation and pharmaceutical compositions containing them
– Google Patents
Taxol derivatives, their preparation and pharmaceutical compositions containing them
Info
Publication number
AU7567787A
AU7567787A
AU75677/87A
AU7567787A
AU7567787A
AU 7567787 A
AU7567787 A
AU 7567787A
AU 75677/87 A
AU75677/87 A
AU 75677/87A
AU 7567787 A
AU7567787 A
AU 7567787A
AU 7567787 A
AU7567787 A
AU 7567787A
Authority
AU
Australia
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
taxol derivatives
taxol
Prior art date
1986-07-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU75677/87A
Other versions
AU591309B2
(en
Inventor
Michel Colin
Daniel Guenard
Francoise Gueritte-Voegelein
Pierre Potier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1986-07-17
Filing date
1987-07-15
Publication date
1988-01-21
Family has litigation
First worldwide family litigation filed
litigation
Critical
https://patents.darts-ip.com/?family=9337506&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU7567787(A)
«Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
1987-07-15
Application filed by Rhone Poulenc Sante SA
filed
Critical
Rhone Poulenc Sante SA
1988-01-21
Publication of AU7567787A
publication
Critical
patent/AU7567787A/en
1989-11-30
Application granted
granted
Critical
1989-11-30
Publication of AU591309B2
publication
Critical
patent/AU591309B2/en
2010-04-15
Assigned to AVENTIS PHARMA S.A.
reassignment
AVENTIS PHARMA S.A.
Request to Amend Deed and Register
Assignors: RHONE-POULENC SANTE
2011-02-06
Adjusted expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P31/12—Antivirals
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P35/00—Antineoplastic agents
Abstract
Taxol derivatives of formula
AU75677/87A
1986-07-17
1987-07-15
Taxol derivatives, their preparation and pharmaceutical compositions containing them
Expired
AU591309B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
FR8610400A
FR2601675B1
(en)
1986-07-17
1986-07-17
TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR8610400
1986-07-17
Publications (2)
Publication Number
Publication Date
AU7567787A
true
AU7567787A
(en)
1988-01-21
AU591309B2
AU591309B2
(en)
1989-11-30
Family
ID=9337506
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU75677/87A
Expired
AU591309B2
(en)
1986-07-17
1987-07-15
Taxol derivatives, their preparation and pharmaceutical compositions containing them
Country Status (15)
Country
Link
US
(1)
US4814470A
(en)
EP
(1)
EP0253738B1
(en)
JP
(1)
JPH0651689B2
(en)
KR
(1)
KR950006153B1
(en)
AT
(1)
ATE49962T1
(en)
AU
(1)
AU591309B2
(en)
CA
(1)
CA1278304C
(en)
DE
(1)
DE3761562D1
(en)
ES
(1)
ES2012809B3
(en)
FR
(1)
FR2601675B1
(en)
GR
(1)
GR3000287T3
(en)
LU
(1)
LU88712I2
(en)
MX
(1)
MX9203385A
(en)
NL
(1)
NL960002I2
(en)
ZA
(1)
ZA875179B
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU620605B2
(en)
*
1988-03-07
1992-02-20
United States of America, as represented by the Secretary, U.S. Department of Commerce, The
New, water soluble, antineoplastic derivatives of taxol
Families Citing this family (345)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FR2629819B1
(en)
*
1988-04-06
1990-11-16
Rhone Poulenc Sante
PROCESS FOR THE PREPARATION OF BACCATIN III AND DESACETYL-10 BACCATIN III DERIVATIVES
FR2629818B1
(en)
*
1988-04-06
1990-11-16
Centre Nat Rech Scient
PROCESS FOR THE PREPARATION OF TAXOL
USRE34277E
(en)
*
1988-04-06
1993-06-08
Centre National De La Recherche Scientifique
Process for preparing taxol
US4960790A
(en)
*
1989-03-09
1990-10-02
University Of Kansas
Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
MY110249A
(en)
*
1989-05-31
1998-03-31
Univ Florida State
Method for preparation of taxol using beta lactam
US5175315A
(en)
*
1989-05-31
1992-12-29
Florida State University
Method for preparation of taxol using β-lactam
US5304670A
(en)
*
1989-08-23
1994-04-19
Centre National De La Recherche Scientifique
Process for the enantioselective preparation of phenylisoserine derivatives
FR2651226B1
(en)
*
1989-08-23
1993-01-08
Centre Nat Rech Scient
PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
IL95436A
(en)
*
1989-08-23
1996-07-23
Centre Nat Rech Scient
Method for the preparation of phenzlisoserine derivatives
US5015744A
(en)
*
1989-11-14
1991-05-14
Florida State University
Method for preparation of taxol using an oxazinone
US5136060A
(en)
*
1989-11-14
1992-08-04
Florida State University
Method for preparation of taxol using an oxazinone
FR2658513B1
(en)
*
1990-02-21
1994-02-04
Rhone Poulenc Sante
PROCESS FOR THE PREPARATION OF CIS-BETA-PHENYLGLYCIDIC- (2R, 3R) ACID.
FR2662441B1
(en)
*
1990-05-22
1992-10-23
Rhone Poulenc Sante
PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
FR2662440B1
(en)
*
1990-05-22
1992-07-31
Rhone Poulenc Sante
PROCESS FOR THE STEREOSELECTIVE PREPARATION OF PHENYLISOSERIN DERIVATIVES.
US5059699A
(en)
*
1990-08-28
1991-10-22
Virginia Tech Intellectual Properties, Inc.
Water soluble derivatives of taxol
US5380916A
(en)
*
1990-11-02
1995-01-10
University Of Florida
Method for the isolation and purification of taxane derivatives
US5475120A
(en)
*
1990-11-02
1995-12-12
University Of Florida
Method for the isolation and purification of taxol and its natural analogues
FR2669631B1
(en)
*
1990-11-23
1994-09-09
Rhone Poulenc Rorer Sa
NEW OXAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE.
ATE180477T1
(en)
*
1991-04-19
1999-06-15
Univ Mississippi
METHOD AND PREPARATIONS FOR ISOLATION OF TAXANS
US6150398A
(en)
*
1991-05-08
2000-11-21
The United States Of America As Represented By The Department Of Health And Human Services
Methods for the treatment of cancer
CA2072400C
(en)
*
1991-07-05
2003-08-19
Jayaprakash B. Nair
Supercritical extraction of taxanes
FR2678833B1
(en)
*
1991-07-08
1995-04-07
Rhone Poulenc Rorer Sa
NEW PHARMACEUTICAL COMPOSITIONS BASED ON DERIVATIVES OF THE TAXANE CLASS.
US5698582A
(en)
*
1991-07-08
1997-12-16
Rhone-Poulenc Rorer S.A.
Compositions containing taxane derivatives
US5750561A
(en)
*
1991-07-08
1998-05-12
Rhone-Poulenc Rorer, S.A.
Compositions containing taxane derivatives
FR2678930B1
(en)
*
1991-07-10
1995-01-13
Rhone Poulenc Rorer Sa
PROCESS FOR THE PREPARATION OF DERIVATIVES OF BACCATIN III AND DESACETYL-10 BACCATIN III.
FR2679230B1
(en)
*
1991-07-16
1993-11-19
Rhone Poulenc Rorer Sa
NOVEL DERIVATIVES OF TAXOL ANALOGS, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
US5229526A
(en)
*
1991-09-23
1993-07-20
Florida State University
Metal alkoxides
US5721268A
(en)
*
1991-09-23
1998-02-24
Florida State University
C7 taxane derivatives and pharmaceutical compositions containing them
US5998656A
(en)
*
1991-09-23
1999-12-07
Florida State University
C10 tricyclic taxanes
US5710287A
(en)
*
1991-09-23
1998-01-20
Florida State University
Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US6794523B2
(en)
1991-09-23
2004-09-21
Florida State University
Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5283253A
(en)
*
1991-09-23
1994-02-01
Florida State University
Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5227400A
(en)
*
1991-09-23
1993-07-13
Florida State University
Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5714513A
(en)
*
1991-09-23
1998-02-03
Florida State University
C10 taxane derivatives and pharmaceutical compositions
SG46582A1
(en)
*
1991-09-23
1998-02-20
Univ Florida State
10-Desacetoxytaxol derivatives
US5250683A
(en)
*
1991-09-23
1993-10-05
Florida State University
Certain substituted taxanes and pharmaceutical compositions containing them
US6335362B1
(en)
1991-09-23
2002-01-01
Florida State University
Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US5728725A
(en)
*
1991-09-23
1998-03-17
Florida State University
C2 taxane derivaties and pharmaceutical compositions containing them
US5739362A
(en)
*
1991-09-23
1998-04-14
Florida State University
Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US6018073A
(en)
*
1991-09-23
2000-01-25
Florida State University
Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US7074945B2
(en)
*
1991-09-23
2006-07-11
Florida State University
Metal alkoxide taxane derivatives
US5284865A
(en)
*
1991-09-23
1994-02-08
Holton Robert A
Cyclohexyl substituted taxanes and pharmaceutical compositions containing them
US5243045A
(en)
*
1991-09-23
1993-09-07
Florida State University
Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5990325A
(en)
*
1993-03-05
1999-11-23
Florida State University
Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US5430160A
(en)
*
1991-09-23
1995-07-04
Florida State University
Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
US6005138A
(en)
*
1991-09-23
1999-12-21
Florida State University
Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5399726A
(en)
1993-01-29
1995-03-21
Florida State University
Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US5654447A
(en)
*
1991-09-23
1997-08-05
Florida State University
Process for the preparation of 10-desacetoxybaccatin III
US6028205A
(en)
*
1991-09-23
2000-02-22
Florida State University
C2 tricyclic taxanes
US6011056A
(en)
1991-09-23
2000-01-04
Florida State University
C9 taxane derivatives and pharmaceutical compositions containing them
US5274124A
(en)
*
1991-09-23
1993-12-28
Florida State University
Metal alkoxides
US6495704B1
(en)
1991-09-23
2002-12-17
Florida State University
9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US5728850A
(en)
*
1991-09-23
1998-03-17
Florida State University
Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5489601A
(en)
*
1991-09-23
1996-02-06
Florida State University
Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
EP0552041B1
(en)
*
1992-01-15
2000-08-30
E.R. Squibb & Sons, Inc.
Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
US6080777A
(en)
*
1992-01-31
2000-06-27
The Trustees Of Columbia University In The City Of New York
Taxol as a radiation sensitizer
CA2128693A1
(en)
*
1992-01-31
1993-08-05
Peter B. Schiff
Taxol as a radiation sensitizer
US5272171A
(en)
*
1992-02-13
1993-12-21
Bristol-Myers Squibb Company
Phosphonooxy and carbonate derivatives of taxol
US5294737A
(en)
*
1992-02-27
1994-03-15
The Research Foundation State University Of New York
Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom
US5445809A
(en)
*
1992-03-03
1995-08-29
Research And Development Institute At Montana State University
Production of taxol from the yew tree
US5451392A
(en)
*
1992-03-03
1995-09-19
The Research And Development Institute At Montana State University
Production of taxol
US5200534A
(en)
*
1992-03-13
1993-04-06
University Of Florida
Process for the preparation of taxol and 10-deacetyltaxol
FR2688518B1
(en)
*
1992-03-13
1994-05-06
Rhone Poulenc Rorer Sa
PROCESS FOR THE PREPARATION OF TAXANE DERIVATIVES.
US5254703A
(en)
*
1992-04-06
1993-10-19
Florida State University
Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones
US5322779A
(en)
*
1992-04-16
1994-06-21
The Research And Development Institute, Inc. At Montana State University
Taxol production by taxomyces andreanae
DE69325454T2
(en)
*
1992-04-17
2000-01-20
Abbott Lab
TAXOL DERIVATIVES
JPH069600A
(en)
*
1992-05-06
1994-01-18
Bristol Myers Squibb Co
Benzoate derivative of taxole
FR2691460B1
(en)
*
1992-05-21
1994-07-22
Rhone Poulenc Rorer Sa
NEW TAXANE DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
US5284944A
(en)
*
1992-06-30
1994-02-08
Lever Brothers Company, Division Of Conopco, Inc.
Improved synthesis of 1,4,7-triazacyclononane
US5254580A
(en)
*
1993-01-19
1993-10-19
Bristol-Myers Squibb Company
7,8-cyclopropataxanes
US5294637A
(en)
*
1992-07-01
1994-03-15
Bristol-Myers Squibb Company
Fluoro taxols
US5364947A
(en)
*
1992-07-02
1994-11-15
Hauser Chemical Research, Inc.
Process for separating cephalomannine from taxol using ozone and water-soluble hydrazines or hydrazides
FR2693193B1
(en)
*
1992-07-03
1994-09-02
Rhone Poulenc Rorer Sa
New derivatives of 10-deacetyl baccatin III, their preparation and the pharmaceutical compositions containing them.
CA2086874E
(en)
*
1992-08-03
2000-01-04
Renzo Mauro Canetta
Methods for administration of taxol
US5319112A
(en)
*
1992-08-18
1994-06-07
Virgnia Tech Intellectual Properties, Inc.
Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol
US5470866A
(en)
*
1992-08-18
1995-11-28
Virginia Polytechnic Institute And State University
Method for the conversion of cephalomannine to taxol and for the preparation of n-acyl analogs of taxol
US5614549A
(en)
*
1992-08-21
1997-03-25
Enzon, Inc.
High molecular weight polymer-based prodrugs
US5789189A
(en)
*
1993-09-24
1998-08-04
The Regents Of The University Of California
Inhibition of cyst formation by cytoskeletal specific drugs
FR2696461B1
(en)
*
1992-10-05
1994-11-10
Rhone Poulenc Rorer Sa
New derivatives of taxol analogs, their preparation and compositions containing them.
FR2696459B1
(en)
1992-10-05
1994-11-25
Rhone Poulenc Rorer Sa
Process for the preparation of taxane derivatives.
FR2696460B1
(en)
1992-10-05
1994-11-25
Rhone Poulenc Rorer Sa
Process for the preparation of taxane derivatives.
FR2696463B1
(en)
1992-10-05
1994-11-25
Rhone Poulenc Rorer Sa
Process for obtaining 10-deacetyl baccatin III.
FR2696462B1
(en)
*
1992-10-05
1994-11-25
Rhone Poulenc Rorer Sa
Process for obtaining 10-deacetyl baccatin III.
US5411984A
(en)
*
1992-10-16
1995-05-02
Virginia Tech Intellectual Properties, Inc.
Water soluble analogs and prodrugs of taxol
FR2697752B1
(en)
*
1992-11-10
1995-04-14
Rhone Poulenc Rorer Sa
Antitumor compositions containing taxane derivatives.
US5420337A
(en)
*
1992-11-12
1995-05-30
E. R. Squibb & Sons, Inc.
Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
FR2697841B1
(en)
*
1992-11-12
1995-01-13
Rhone Poulenc Rorer Sa
New taxane derivatives, their preparation and the pharmaceutical compositions containing them.
FR2698363B1
(en)
*
1992-11-23
1994-12-30
Rhone Poulenc Rorer Sa
New taxane derivatives, their preparation and the compositions containing them.
KR100371062B1
(en)
*
1992-11-27
2003-04-21
에프.에이치.포울딩 앤드 컴퍼니 리미티드
Injectable taxi brush compositions with improved stability and methods of formulating them
WO1994012030A1
(en)
*
1992-11-27
1994-06-09
Napro Biotherapeutics, Inc.
Injectable composition
US5631278A
(en)
*
1992-12-02
1997-05-20
Thomas Jefferson University
Methods of killing protozoal parasites
FR2698629B1
(en)
*
1992-12-02
1995-01-13
Rhone Poulenc Rorer Sa
New taxoids, their preparation and the pharmaceutical compositions containing them.
FR2698543B1
(en)
*
1992-12-02
1994-12-30
Rhone Poulenc Rorer Sa
New taxoid-based compositions.
US5356927A
(en)
*
1992-12-02
1994-10-18
Thomas Jefferson University
Methods of treating plasmodium and babesia parasitic infections
US5380751A
(en)
*
1992-12-04
1995-01-10
Bristol-Myers Squibb Company
6,7-modified paclitaxels
CA2109861C
(en)
*
1992-12-04
1999-03-16
Shu-Hui Chen
6,7-modified paclitaxels
FR2698871B1
(en)
*
1992-12-09
1995-02-24
Rhone Poulenc Rorer Sa
New taxoids, their preparation and the pharmaceutical compositions containing them.
IL107950A
(en)
1992-12-15
2001-04-30
Upjohn Co
7β, 8β – METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US5973160A
(en)
*
1992-12-23
1999-10-26
Poss; Michael A.
Methods for the preparation of novel sidechain-bearing taxanes
US5646176A
(en)
1992-12-24
1997-07-08
Bristol-Myers Squibb Company
Phosphonooxymethyl ethers of taxane derivatives
US5688517A
(en)
*
1993-01-29
1997-11-18
Napro Biotherapeutics, Inc.
Method for assessing sensitivity of tumor cells to cephalomannine and 10-deacetyltaxol
EP1260507A1
(en)
*
1993-02-05
2002-11-27
Bryn Mawr College
Synthesis of taxol, analogs and intermediates with variable A-nng side chains
FR2702212B1
(en)
*
1993-03-02
1995-04-07
Rhone Poulenc Rorer Sa
New taxoids, their preparation and the pharmaceutical compositions containing them.
US6710191B2
(en)
*
1993-03-05
2004-03-23
Florida State University
9β-hydroxytetracyclic taxanes
EP0687260B1
(en)
*
1993-03-05
2003-02-19
Florida State University
Process for the preparation of 9-desoxotaxanes
US5547981A
(en)
*
1993-03-09
1996-08-20
Enzon, Inc.
Taxol-7-carbazates
WO1994020453A1
(en)
*
1993-03-09
1994-09-15
Enzon, Inc.
Taxol polyalkylene oxide conjugates of taxol and taxol intermediates
US5703247A
(en)
*
1993-03-11
1997-12-30
Virginia Tech Intellectual Properties, Inc.
2-Debenzoyl-2-acyl taxol derivatives and methods for making same
TW467896B
(en)
*
1993-03-19
2001-12-11
Bristol Myers Squibb Co
Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
PT690867E
(en)
*
1993-03-22
2003-06-30
Univ Florida State
TAXANOS HAVING A SUBSTITUTE SIDE CHAIN WITH FURY OR TIENILO
FR2703049B1
(en)
*
1993-03-22
1995-04-21
Rhone Poulenc Rorer Sa
Method for the purification of taxoids.
US5336684A
(en)
*
1993-04-26
1994-08-09
Hauser Chemical Research, Inc.
Oxidation products of cephalomannine
CA2161328A1
(en)
*
1993-06-11
1994-12-22
Robert C. Kelly
Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them
FR2707165B1
(en)
*
1993-07-06
1995-08-11
Rhone Poulenc Rorer Sa
Application of taxoids to the treatment of parasitic diseases.
US6005120A
(en)
*
1993-07-20
1999-12-21
Florida State University
Tricyclic and tetracyclic taxanes
US5405972A
(en)
*
1993-07-20
1995-04-11
Florida State University
Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
CA2174350A1
(en)
*
1993-10-20
1995-04-27
Richard B. Greenwald
2′- and/or 7- substituted taxoids
US5880131A
(en)
*
1993-10-20
1999-03-09
Enzon, Inc.
High molecular weight polymer-based prodrugs
US5965566A
(en)
*
1993-10-20
1999-10-12
Enzon, Inc.
High molecular weight polymer-based prodrugs
US6441026B1
(en)
1993-11-08
2002-08-27
Aventis Pharma S.A.
Antitumor compositions containing taxane derivatives
US5415869A
(en)
*
1993-11-12
1995-05-16
The Research Foundation Of State University Of New York
Taxol formulation
IL112412A
(en)
*
1994-01-28
2000-02-29
Upjohn Co
Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them
GB9405400D0
(en)
*
1994-03-18
1994-05-04
Erba Carlo Spa
Taxane derivatives
DE4416374A1
(en)
*
1994-05-05
1995-11-09
Schering Ag
New borneol derivatives, processes for their production and their pharmaceutical use
US5508447A
(en)
*
1994-05-24
1996-04-16
Board Of Regents, The University Of Texas System
Short synthetic route to taxol and taxol derivatives
US5602272A
(en)
*
1994-06-21
1997-02-11
Bristol-Myers Squibb Company
Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes
US5677470A
(en)
1994-06-28
1997-10-14
Tanabe Seiyaku Co., Ltd.
Baccatin derivatives and processes for preparing the same
FR2722191B1
(en)
*
1994-07-08
1996-08-23
Rhone Poulenc Rorer Sa
PROCESS FOR THE PREPARATION OF (2R, 3S) -3-TERTBUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE (2R, 3S) TRIHYDRATE, 20EPOXY-11BYA -13ALPHA-YLE
FR2723094A1
(en)
*
1994-07-26
1996-02-02
Rhone Poulenc Rorer Sa
NOVEL TAXOIDS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US6201140B1
(en)
1994-07-28
2001-03-13
Bristol-Myers Squibb Company
7-0-ethers of taxane derivatives
CA2163837C
(en)
†
1994-12-13
1999-07-20
Robert K. Perrone
Crystalline paclitaxel hydrates
JPH10510812A
(en)
*
1994-12-15
1998-10-20
ベーカー ノートン ファーマスーティカルズ、インコーポレーテッド
Methods and compositions for reducing tumor growth by using a combination of a taxane compound and a tellurium and / or selenium compound
CA2170661A1
(en)
1995-03-22
1996-09-23
John K. Thottathil
Novel methods for the preparation of taxanes using oaxzolidine intermediates
US5840929A
(en)
*
1995-04-14
1998-11-24
Bristol-Myers Squibb Company
C4 methoxy ether derivatives of paclitaxel
AU716005B2
(en)
*
1995-06-07
2000-02-17
Cook Medical Technologies Llc
Implantable medical device
US6177456B1
(en)
1995-10-02
2001-01-23
Xechem International, Inc.
Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
US5840748A
(en)
*
1995-10-02
1998-11-24
Xechem International, Inc.
Dihalocephalomannine and methods of use therefor
US5807888A
(en)
*
1995-12-13
1998-09-15
Xechem International, Inc.
Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US5854278A
(en)
*
1995-12-13
1998-12-29
Xechem International, Inc.
Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US5654448A
(en)
*
1995-10-02
1997-08-05
Xechem International, Inc.
Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
CN1209059A
(en)
*
1995-12-21
1999-02-24
基因实验室技术有限公司
Taxane compositions and method for producing same
FR2743074B1
(en)
*
1995-12-27
1998-03-27
Seripharm
METHOD FOR THE SELECTIVE PROTECTION OF BACCATIN DERIVATIVES AND ITS USE IN THE SYNTHESIS OF TAXANES
US6107497A
(en)
*
1996-02-29
2000-08-22
Napro Biotherapeutics, Inc.
Intermediate for use in docetaxel synthesis and production method therefor
US5688977A
(en)
*
1996-02-29
1997-11-18
Napro Biotherapeutics, Inc.
Method for docetaxel synthesis
CA2253513A1
(en)
1996-05-06
1997-11-13
Florida State University
1-deoxy baccatin iii, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof
DE69715417T2
(en)
1996-05-08
2003-06-05
Upjohn Co
oxazolidine ester
IT1283633B1
(en)
*
1996-05-10
1998-04-23
Indena Spa
TAXANIC DERIVATIVES THEIR SUMMARY AND FORMULATIONS CONTAINING THEM
EP0914116B1
(en)
*
1996-05-22
2000-10-11
Protarga Inc.
Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
US5919815A
(en)
*
1996-05-22
1999-07-06
Neuromedica, Inc.
Taxane compounds and compositions
US6576636B2
(en)
*
1996-05-22
2003-06-10
Protarga, Inc.
Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5795909A
(en)
*
1996-05-22
1998-08-18
Neuromedica, Inc.
DHA-pharmaceutical agent conjugates of taxanes
KR20040097250A
(en)
1996-05-24
2004-11-17
유니버시티 오브 브리티시 콜롬비아
Compositions and methods for treating or preventing diseases of body passageways
US5635531A
(en)
*
1996-07-08
1997-06-03
Bristol-Myers Squibb Company
3′-aminocarbonyloxy paclitaxels
US5750737A
(en)
*
1996-09-25
1998-05-12
Sisti; Nicholas J.
Method for paclitaxel synthesis
US5773464A
(en)
*
1996-09-30
1998-06-30
Bristol-Myers Squibb Company
C-10 epoxy taxanes
US5977386A
(en)
*
1996-12-24
1999-11-02
Bristol-Myers Squibb Company
6-thio-substituted paclitaxels
US5902822A
(en)
*
1997-02-28
1999-05-11
Bristol-Myers Squibb Company
7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
US5912264A
(en)
*
1997-03-03
1999-06-15
Bristol-Myers Squibb Company
6-halo-or nitrate-substituted paclitaxels
US6017935A
(en)
*
1997-04-24
2000-01-25
Bristol-Myers Squibb Company
7-sulfur substituted paclitaxels
HU0002922A3
(en)
*
1997-04-28
2003-03-28
Aventis Pharma Sa
Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
BE1011216A3
(en)
*
1997-06-13
1999-06-01
Thissen En Abrege L T B Lab
Pharmaceutical form for the administration of paclitaxel, method of preparation of a composition paclitaxel ready to employment and use thereof.
WO1999025729A1
(en)
*
1997-11-18
1999-05-27
Chugai Seiyaku Kabushiki Kaisha
Compounds with antitumor activity
US5917062A
(en)
*
1997-11-21
1999-06-29
Indena S.P.A
Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
US6235782B1
(en)
1998-11-12
2001-05-22
Rifat Pamukcu
Method for treating a patient with neoplasia by treatment with a platinum coordination complex
US6235776B1
(en)
*
1998-11-12
2001-05-22
Cell Pathways, Inc.
Method for treating a patient with neoplasia by treatment with a paclitaxel derivative
US7235583B1
(en)
1999-03-09
2007-06-26
Luitpold Pharmaceuticals, Inc.,
Fatty acid-anticancer conjugates and uses thereof
FR2794771B1
(en)
*
1999-06-11
2001-08-10
Aventis Pharma Sa
RECOMBINANT ADENOVIRUSES ENCODING THE IODINE SPECIFIC TRANSPORTER (NIS)
GB9920548D0
(en)
*
1999-08-31
1999-11-03
Rhone Poulenc Rorer Sa
Treatment of hepatocellular carcinoma
CA2385528C
(en)
1999-10-01
2013-12-10
Immunogen, Inc.
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
PT1233787E
(en)
*
1999-11-09
2005-04-29
Conseils Rech S Et D Applic Sc
PRODUCT CONTAINING AN INHIBITOR OF TRANSDUCING THE SIGNS OF GHETEROTRIMERAL PROTEINS IN ASSOCIATION WITH ANOTHER ANTICANCEROSOUS AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT
MXPA01009902A
(en)
*
2000-02-02
2003-07-28
Univ Florida State Res Found
C10 carbonate substituted taxanes as antitumor agents.
CA2368274C
(en)
*
2000-02-02
2009-10-13
Florida State University Research Foundation, Inc.
C10 ester substituted taxanes as antitumor agents
US6649632B2
(en)
*
2000-02-02
2003-11-18
Fsu Research Foundation, Inc.
C10 ester substituted taxanes
JP2003522170A
(en)
*
2000-02-02
2003-07-22
フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド
C7 carbonate substituted taxanes as antitumor agents
CO5280224A1
(en)
*
2000-02-02
2003-05-30
Univ Florida State Res Found
SUBSTITUTED TAXANS WITH ESTER IN C7, USEFUL AS ANTITUMOR AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US20030181473A1
(en)
*
2000-02-29
2003-09-25
Palmer Peter Albert
Farnesyl protein transferase inhibitor combinations with taxane compounds
US6362217B2
(en)
2000-03-17
2002-03-26
Bristol-Myers Squibb Company
Taxane anticancer agents
US6638742B1
(en)
2000-07-07
2003-10-28
University Of Portland
Methods for obtaining taxanes
CA2422964A1
(en)
2000-09-22
2002-03-28
Bristol Myers Squibb Company
Method for reducing toxicity of combined chemotherapies
US6919370B2
(en)
*
2000-11-28
2005-07-19
Transform Pharmaceuticals, Inc.
Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
KR20020066808A
(en)
*
2001-02-14
2002-08-21
주식회사 삼양제넥스
Synthesis of taxane derivaties by asymmetric aminohydroxylation
US20030157170A1
(en)
*
2001-03-13
2003-08-21
Richard Liggins
Micellar drug delivery vehicles and precursors thereto and uses thereof
US20030054036A1
(en)
*
2001-03-13
2003-03-20
Richard Liggins
Micellar drug delivery vehicles and precursors thereto and uses thereof
US20020183266A1
(en)
2001-03-15
2002-12-05
Aventis Pharma, S.A.
Combination comprising combretastatin and anticancer agents
WO2002076402A2
(en)
*
2001-03-23
2002-10-03
Protarga, Inc.
Fatty amine drug conjugates
JP4634694B2
(en)
*
2001-03-23
2011-02-16
ルイトポルド・ファーマシューティカルズ・インコーポレーテッド
Fatty alcohol drug complex
UY27220A1
(en)
*
2001-03-23
2002-09-30
Aventis Pharma Sa
COMBINATION OF A TAXAN WITH A CYCLINE-DEPENDENT KINASE
NZ529647A
(en)
*
2001-04-20
2007-05-31
Univ British Columbia
Micellar drug delivery systems for hydrophobic drugs
US6479679B1
(en)
2001-04-25
2002-11-12
Napro Biotherapeutics, Inc.
Two-step conversion of protected taxane ester to paclitaxel
US6452025B1
(en)
2001-04-25
2002-09-17
Napro Biotherapeutics, Inc.
Three-step conversion of protected taxane ester to paclitaxel
CA2466851C
(en)
*
2001-11-26
2012-09-11
Supergen, Inc.
Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
US20040092428A1
(en)
*
2001-11-27
2004-05-13
Hongming Chen
Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof
EP1451168A4
(en)
*
2001-11-30
2005-08-24
Bristol Myers Squibb Co
Paclitaxel solvates
AU2002361701A1
(en)
*
2001-12-20
2003-07-09
Bristol-Myers Squibb Company
Pharmaceutical compositons of orally active taxane derivatives having enhanced bioavailability
US20030216758A1
(en)
*
2001-12-28
2003-11-20
Angiotech Pharmaceuticals, Inc.
Coated surgical patches
EP2316469A1
(en)
2002-02-22
2011-05-04
Shire LLC
Delivery system and methods for protecting and administering dextroamphetamine
IL165214A0
(en)
2002-05-17
2005-12-18
Aventis Pharma Sa
Use of docetaxel/doxorubicin/cyclophosphamide in adjuvant therapy of breast and ovarian cancer
BR122012021252B8
(en)
2002-09-06
2021-05-25
Cerulean Pharma Inc
cyclodextrin-based polymers for the delivery of covalently linked therapeutic agents
US20080220074A1
(en)
*
2002-10-04
2008-09-11
Elan Corporation Plc
Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
AU2003273671A1
(en)
*
2002-10-09
2004-05-04
Phytogen Life Sciences, Inc.
Novel taxanes and methods related to use and preparation thereof
AU2003300076C1
(en)
2002-12-30
2010-03-04
Angiotech International Ag
Drug delivery from rapid gelling polymer composition
US8703982B2
(en)
2003-03-17
2014-04-22
Phyton Holdings Llc
Purification of taxanes
CN1268619C
(en)
*
2003-05-08
2006-08-09
上海迪赛诺化学制药有限公司
Prepn of polyene taxol trihydrate
US7202370B2
(en)
2003-10-27
2007-04-10
Conor Medsystems, Inc.
Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
US20060034943A1
(en)
*
2003-10-31
2006-02-16
Technology Innovations Llc
Process for treating a biological organism
GT200500025A
(en)
*
2004-02-13
2005-09-30
REPLACED TAXANS WITH CYCLOPENTILO ESTERS IN C10
PE20050693A1
(en)
*
2004-02-13
2005-09-27
Univ Florida State Res Found
TAXANS REPLACED WITH CYCLOPENTIL ESTERS IN C10
US20050192445A1
(en)
*
2004-03-01
2005-09-01
Phytogen Life Sciences Inc.
Semi-synthesis of taxane intermediates and aziridine analogues and their conversion to paclitaxel and docetaxel
US7989490B2
(en)
*
2004-06-02
2011-08-02
Cordis Corporation
Injectable formulations of taxanes for cad treatment
US8003122B2
(en)
*
2004-03-31
2011-08-23
Cordis Corporation
Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7846940B2
(en)
*
2004-03-31
2010-12-07
Cordis Corporation
Solution formulations of sirolimus and its analogs for CAD treatment
CN101146532B
(en)
2005-01-21
2012-05-09
阿斯泰克斯治疗有限公司
Pharmaceutical compounds
EP1848423A4
(en)
*
2005-02-14
2008-12-31
Univ Florida State Res Found
C10 cyclopropyl ester substituted taxane compositions
CN1300131C
(en)
*
2005-04-27
2007-02-14
浙江钱江生物化学股份有限公司
Separation method for purifying gibberellin GA3
CA2653541C
(en)
2005-06-06
2014-12-23
The University Of British Columbia
Polymer-based serum albumin substitute
WO2006133510A1
(en)
2005-06-17
2006-12-21
Hospira Australia Pty Ltd
Liquid pharmaceutical formulations of docetaxel
CN1314675C
(en)
*
2005-07-01
2007-05-09
中国科学院上海有机化学研究所
Taxol derivatives
KR101457834B1
(en)
*
2005-08-31
2014-11-05
아브락시스 바이오사이언스, 엘엘씨
Compositions and methods for preparation of poorly water soluble drugs with increased stability
CN101291659A
(en)
*
2005-08-31
2008-10-22
阿布拉科斯生物科学有限公司
Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
US20070073385A1
(en)
*
2005-09-20
2007-03-29
Cook Incorporated
Eluting, implantable medical device
US20070196423A1
(en)
*
2005-11-21
2007-08-23
Med Institute, Inc.
Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent
AR054215A1
(en)
*
2006-01-20
2007-06-13
Eriochem Sa
A PHARMACEUTICAL FORMULATION OF A TAXANE, A SOLID COMPOSITION OF A LIOFILIZED TAXAN FROM AN ACETIC ACID SOLUTION, A PROCEDURE FOR THE PREPARATION OF A SOLID COMPOSITION OF A TAXANE, A SOLUBILIZING COMPOSITION OF A LIOFILIZED TAXANE AND AN ELEMENTARY KIT
EP1998808A1
(en)
2006-02-21
2008-12-10
Dabur Pharma Limited
Stable pharmaceutical composition of taxanes
US20090026763A1
(en)
*
2006-03-06
2009-01-29
Acs Industries, Inc.
Sliding Sealing Connector
KR101009467B1
(en)
*
2006-03-13
2011-01-19
주식회사 셀트리온화학연구소
Taxan derivative useful for synthesizing docetaxel and a method for preparing the same
KR20080100264A
(en)
*
2006-03-21
2008-11-14
닥터 레디스 레보러터리즈 리미티드
Docetaxel polymorphs and processes
US20070231916A1
(en)
*
2006-03-29
2007-10-04
Cangen Biotechnologies, Inc.
Apparatus and method for filtration to enhance the detection of peaks
KR20090027608A
(en)
*
2006-03-29
2009-03-17
칸젠 바이오테크날러지즈, 인코포레이티드
Methods of predicting response to a treatment for a disease
US20070231915A1
(en)
*
2006-03-29
2007-10-04
Cangen Biotechnologies, Inc.
Apparatus and method for filtration to enhance the detection of peaks
US20070231917A1
(en)
*
2006-03-29
2007-10-04
Cangen Biotechnologies, Inc.
Apparatus and method for filtration to enhance the detection of peaks
WO2007126901A2
(en)
*
2006-03-29
2007-11-08
Cangen Biotechnologies, Inc.
Apparatus and method for predicting disease
US20070238193A1
(en)
*
2006-03-29
2007-10-11
Cangen Biotechnologies, Inc.
Apparatus and method for filtration to enhance the detection of peaks
CN100417649C
(en)
*
2006-04-05
2008-09-10
云南思摩贝特生物科技有限公司
Preparation method of doxytasai
PL217731B1
(en)
2006-06-01
2014-08-29
Tomasz Byrski
Detection of lowered response for chemotherapy with the use of cytostatics from a group of toxoids
WO2008005284A2
(en)
2006-06-30
2008-01-10
Cook Incorporated
Methods of manufacturing and modifying taxane coatings for implantable medical devices
US7585865B2
(en)
*
2006-07-21
2009-09-08
The Penn State Research Foundation
Protein kinase C zeta inhibition to treat vascular permeability
US8728527B2
(en)
*
2006-07-24
2014-05-20
Luminus Biosciences, Inc.
Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
AU2007307489A1
(en)
*
2006-10-06
2008-04-17
Takeda Pharmaceutical Company Limited
Combination drug
JP5528807B2
(en)
2006-10-12
2014-06-25
アステックス、セラピューティックス、リミテッド
Compound drug
US8916552B2
(en)
2006-10-12
2014-12-23
Astex Therapeutics Limited
Pharmaceutical combinations
NZ576355A
(en)
*
2006-10-20
2012-04-27
Scinopharm Singapore Pte Ltd
Process for making crystalline anhydrous docetaxel
AU2007308792B2
(en)
*
2006-10-27
2013-01-24
Genentech, Inc.
Antibodies and immunoconjugates and uses therefor
CA2674788A1
(en)
2007-01-08
2008-07-17
Government Of The Usa, As Represented By The Secretary, Department Of He Alth And Human Services
Slco1b3 genotype
JP2010516625A
(en)
2007-01-24
2010-05-20
インサート セラピューティクス， インコーポレイテッド
Polymer-drug conjugates with tether groups for controlled drug delivery
GB0701523D0
(en)
*
2007-01-26
2007-03-07
Chatham Biotec Ltd
Semi-synthetic process for the preparation of taxane derivatives
WO2008102374A1
(en)
*
2007-02-20
2008-08-28
Dabur Pharma Limited
Amorphous form of docetaxel
US20080241215A1
(en)
*
2007-03-28
2008-10-02
Robert Falotico
Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke
EP2146695A4
(en)
*
2007-04-23
2010-05-19
Sun Pharmaceuticals Ind Ltd
Pharmaceutical compositions
NZ581589A
(en)
*
2007-06-22
2012-10-26
Scidose Llc
Solubilized sterile injectable formulation of docetaxel without Tween 80
US20100197944A1
(en)
*
2007-07-04
2010-08-05
Dr. Reddy’s Laboratories Limited
Docetaxel process and polymorphs
AR063111A1
(en)
*
2007-10-03
2008-12-30
Eriochem Sa
A PHARMACEUTICAL FORMULATION OF TAXANO
EA034136B1
(en)
2007-11-09
2020-01-09
Перигрин Фармасьютикалз, Инк.
Isolated antibody that binds to vegf and uses thereof
AU2007361151A1
(en)
*
2007-11-15
2009-05-22
Institute Of Mataria Medica, Chinese Academy Of Medical Sciences
Cephalomannine derivatives and their preparation, medicinal composition and use
JP5667886B2
(en)
2008-03-14
2015-02-12
バイオニューメリック・ファーマスーティカルズ・インコーポレイテッド
Compositions and methods of using the compounds for increasing the survival time of cancer patients
EP2249825B1
(en)
2008-03-14
2015-10-07
Bionumerik Pharmaceuticals, Inc.
Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions
SG10201401942PA
(en)
2008-03-18
2014-08-28
Genentech Inc
Combinations Of An Anti-Her2 Antibody-Drug Conjugate And Chemotherapeutic Agents, And Methods Of Use
US8420110B2
(en)
2008-03-31
2013-04-16
Cordis Corporation
Drug coated expandable devices
US8409601B2
(en)
*
2008-03-31
2013-04-02
Cordis Corporation
Rapamycin coated expandable devices
EP2276755A4
(en)
*
2008-03-31
2011-05-04
Univ Florida State Res Found
C(10) ethyl ester and c(10) cyclopropyl ester substituted taxanes
CA2723654A1
(en)
*
2008-05-07
2009-11-12
Ivax Research, Llc
Processes for preparation of taxanes and intermediates thereof
US8273404B2
(en)
2008-05-19
2012-09-25
Cordis Corporation
Extraction of solvents from drug containing polymer reservoirs
US8173621B2
(en)
2008-06-11
2012-05-08
Gilead Pharmasset Llc
Nucleoside cyclicphosphates
US9447049B2
(en)
2010-03-01
2016-09-20
University Of Tennessee Research Foundation
Compounds for treatment of cancer
JP5588983B2
(en)
2008-08-11
2014-09-10
ウェルズ ファーゴ バンク ナショナル アソシエイション
Multi-arm polymer alkanoate conjugate
US8642063B2
(en)
*
2008-08-22
2014-02-04
Cook Medical Technologies Llc
Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
US9198968B2
(en)
2008-09-15
2015-12-01
The Spectranetics Corporation
Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8541360B2
(en)
*
2008-11-19
2013-09-24
Ben Venue Laboratories, Inc.
Parenteral formulations comprising sugar-based esters and ethers
KR20100060351A
(en)
2008-11-27
2010-06-07
한국생명공학연구원
A composition for treating l1cam-expressing cancer comprising an inhibitor of activity or expression of l1cam and anticancer agent
FR2939665B1
(en)
2008-12-12
2011-10-07
Sanofi Aventis
ANTITUMOR COMBINATION ASSOCIATING WITH AVE8062A AND DOCETAXEL
TW201031675A
(en)
2008-12-23
2010-09-01
Pharmasset Inc
Synthesis of purine nucleosides
SG172359A1
(en)
*
2008-12-23
2011-07-28
Pharmasset Inc
Nucleoside phosphoramidates
CN102753563A
(en)
*
2008-12-23
2012-10-24
吉利德制药有限责任公司
Nucleoside analogs
CA2754909A1
(en)
2009-03-11
2010-09-16
Ambit Biosciences Corp.
Combination of an indazolylaminopyrrolotriazine and taxane for cancer treatment
PL388144A1
(en)
2009-05-29
2010-12-06
Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością
(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate 4-acetoxy-2?-benzoiloxy-5� ,20-epoxy-1, 7�, 10�-trihydroxy-9-oxo-taks-11 -en-13?-yl solvates, a method for their production and application thereof
US7772274B1
(en)
2009-10-19
2010-08-10
Scidose, Llc
Docetaxel formulations with lipoic acid
US8541465B2
(en)
*
2009-10-19
2013-09-24
Scidose, Llc
Docetaxel formulations with lipoic acid and/or dihydrolipoic acid
US8912228B2
(en)
2009-10-19
2014-12-16
Scidose Llc
Docetaxel formulations with lipoic acid
US20110092579A1
(en)
*
2009-10-19
2011-04-21
Scidose Llc
Solubilized formulation of docetaxel
US8476310B2
(en)
2009-10-19
2013-07-02
Scidose Llc
Docetaxel formulations with lipoic acid
SG10201810928SA
(en)
2009-10-29
2019-01-30
Aventis Pharma Sa
Novel antitumoral use of cabazitaxel
WO2011063421A1
(en)
*
2009-11-23
2011-05-26
Cerulean Pharma Inc.
Cyclodextrin-based polymers for therapeutic delivery
AR079256A1
(en)
2009-12-04
2012-01-04
Genentech Inc
METHOD FOR THE TREATMENT OF METASTASIC BREAST CANCER WITH TRASTUZUMAB-MCC-DM1
AU2010338038B2
(en)
2009-12-31
2015-07-09
Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO)
Tricyclic compounds for use as kinase inhibitors
WO2011089400A1
(en)
2010-01-22
2011-07-28
Centro Nacional De Investigaciones Oncológicas (Cnio)
Inhibitors of pi3 kinase
SG183361A1
(en)
2010-02-18
2012-09-27
Ct Nac Investigaciones Oncologicas Cnio
Triazolo [4, 5 – b] pyridin derivatives
US11084811B2
(en)
2010-03-01
2021-08-10
Oncternal Therapeutics, Inc.
Compounds for treatment of cancer
CN102906157B
(en)
2010-03-01
2016-08-24
不列颠哥伦比亚大学
Derivative hyperbranched poly glycerine
SI3290428T1
(en)
2010-03-31
2022-01-31
Gilead Pharmasset Llc
Tablet comprising crystalline (s)-isopropyl 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1 (2h)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
WO2011121317A1
(en)
2010-04-01
2011-10-06
Centro Nacional De Investigaciones Oncologicas (Cnio)
Imidazo [2,1-b] [1,3,4] thiadiazoles as protein or lipid kinase inhibitors
AU2011248449B2
(en)
2010-05-03
2016-09-15
Teikoku Pharma Usa, Inc.
Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
CN102296053B
(en)
2010-06-25
2015-03-11
中国医学科学院药物研究所
7-xylosyltaxonoglycosyl hydrolase, nucleotide sequence of gene thereof, and application thereof
RU2013103763A
(en)
2010-07-02
2014-08-10
Ангиохем Инк.
SHORT AND CONTAINING D-AMINO ACIDS POLYEPEPTIDES FOR THERAPEUTIC CONJUGATES AND THEIR APPLICATION
WO2012052745A1
(en)
2010-10-21
2012-04-26
Centro Nacional De Investigaciones Oncológicas (Cnio)
Combinations of pi3k inhibitors with a second anti -tumor agent
US20130331443A1
(en)
2010-12-22
2013-12-12
Nektar Therapeutics
Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012088433A1
(en)
2010-12-22
2012-06-28
Nektar Therapeutics
Deuterated and/or fluorinated taxane derivatives
WO2012088445A1
(en)
2010-12-22
2012-06-28
Nektar Therapeutics
Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
EP2694072B1
(en)
2011-04-01
2017-11-29
Genentech, Inc.
Combination of akt inhibitor compound and abiraterone for use in therapeutic treatments
WO2012131698A1
(en)
2011-04-01
2012-10-04
Shilpa Medicare Limited
Process for preparing docetaxel and its hydrate
JPWO2012157647A1
(en)
2011-05-16
2014-07-31
大鵬薬品工業株式会社
Chemotherapy selection method comprising tegafur, gimeracil, oteracil potassium combination agent and EGFR inhibitor for gastric cancer patients
EP2524918A1
(en)
2011-05-19
2012-11-21
Centro Nacional de Investigaciones Oncológicas (CNIO)
Imidazopyrazines derivates as kinase inhibitors
AU2012257513B2
(en)
2011-05-19
2017-05-11
Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO)
Macrocyclic compounds as protein kinase inhibitors
US20120302954A1
(en)
2011-05-25
2012-11-29
Zhao Jonathon Z
Expandable devices coated with a paclitaxel composition
US20120303115A1
(en)
2011-05-25
2012-11-29
Dadino Ronald C
Expandable devices coated with a rapamycin composition
WO2013005057A1
(en)
2011-07-07
2013-01-10
Centro Nacional De Investigaciones Oncológicas (Cnio)
New compounds
WO2013004984A1
(en)
2011-07-07
2013-01-10
Centro Nacional De Investigaciones Oncologicas (Cnio)
Tricyclic compounds for use as kinase inhibitors
WO2013005041A1
(en)
2011-07-07
2013-01-10
Centro Nacional De Investigaciones Oncológicas (Cnio)
Tricyclic heterocyclic compounds as kinase inhibitors
PT2753355T
(en)
2011-09-08
2019-02-01
Univ New York
Oncolytic herpes simplex virus and therapeutic uses thereof
WO2013051994A1
(en)
2011-10-03
2013-04-11
Moreinx Ab
Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrophobic molecules in fields of medicine including cancer treatment and food related compounds
CN102408397B
(en)
2011-10-19
2014-08-20
上海贝美医药科技有限公司
New taxane derivative and preparation method thereof
US9745631B2
(en)
2011-12-20
2017-08-29
Dana-Farber Cancer Institute, Inc.
Methods for diagnosing and treating oncogenic kras-associated cancer
WO2013130093A1
(en)
2012-03-02
2013-09-06
Genentech, Inc.
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
EP2855698A4
(en)
2012-05-24
2016-03-30
Dana Farber Cancer Inst Inc
Targeting the glutamine to pyruvate pathway for treatment of oncogenic kras-associated cancer
CN109939236A
(en)
2012-06-08
2019-06-28
豪夫迈·罗氏有限公司
Catastrophic selection and the combination of Phosphoinositide-3 kinase inhibitor compound and chemotherapeutics for treating cancer
US9956385B2
(en)
2012-06-28
2018-05-01
The Spectranetics Corporation
Post-processing of a medical device to control morphology and mechanical properties
WO2014014518A1
(en)
2012-07-18
2014-01-23
Dana-Farber Cancer Institute, Inc.
Methods for treating, preventing and predicting risk of developing breast cancer
JO3685B1
(en)
2012-10-01
2020-08-27
Teikoku Pharma Usa Inc
Non-aqueous taxane nanodispersion formulations and methods of using the same
WO2014055493A1
(en)
2012-10-02
2014-04-10
Cerulean Pharma Inc.
Methods and systems for polymer precipitation and generation of particles
US10022356B2
(en)
*
2013-03-05
2018-07-17
University Of Tennessee Research Foundation
Compounds for treatment of cancer
WO2014149871A1
(en)
2013-03-14
2014-09-25
Icahn School Of Medicine At Mount Sinai
Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
US9907846B2
(en)
2013-04-01
2018-03-06
Mx Adjuvac Ab
Nanoparticles, composed of sterol and saponin from Quillaja saponaria Molina for use in pharmaceutical compositions
SG11201509350RA
(en)
2013-06-11
2015-12-30
Bayer Pharma AG
Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor
WO2015050844A1
(en)
2013-10-01
2015-04-09
Dana-Farber Cancer Institute, Inc.
Methods of treating cancer with atovaquone-related compounds
US9783547B2
(en)
2014-01-15
2017-10-10
Centre National De La Recherche Scientifique (Cnrs)
Water soluble 4-azapodophyllotoxin analogs
IL295906A
(en)
2014-03-21
2022-10-01
Abbvie Inc
Anti-egfr antibodies and antibody drug conjugates
US10350264B2
(en)
2014-03-27
2019-07-16
Dana-Farber Cancer Institute, Inc.
Compositions and methods for modulating NCOA4-mediated autophagic targeting of ferritin
MA39818A
(en)
2014-03-30
2017-02-08
Benevir Biopharm Inc
Exogenous tap inhibitor «armed» oncolytic viruses and therapeutic uses thereof
WO2016205429A1
(en)
2015-06-15
2016-12-22
New York University
Method of treatment using oncolytic viruses
HU1500603A2
(en)
*
2015-12-11
2017-06-28
Rotachrom Tech Kft
Process for the separation of 10-deacetyl baccatin iii
CN109195593A
(en)
2016-03-15
2019-01-11
奥莱松基因组股份有限公司
For treating the combination of the LSD1 inhibitor of solid tumor
MX2018015277A
(en)
2016-06-08
2019-09-06
Abbvie Inc
Anti-b7-h3 antibodies and antibody drug conjugates.
EP3468599A2
(en)
2016-06-08
2019-04-17
AbbVie Inc.
Anti-cd98 antibodies and antibody drug conjugates
EP3469000A1
(en)
2016-06-08
2019-04-17
AbbVie Inc.
Anti-b7-h3 antibodies and antibody drug conjugates
JP2019524651A
(en)
2016-06-08
2019-09-05
アッヴィ・インコーポレイテッド
Anti-CD98 antibodies and antibody drug conjugates
RS61828B1
(en)
2016-06-08
2021-06-30
Abbvie Inc
Anti-b7-h3 antibodies and antibody drug conjugates
DK3532059T3
(en)
2016-10-27
2022-03-14
Celgene Quanticel Res Inc
COMBINATION THERAPY WITH BROMDOMAIN AND EXTRA TERMINAL PROTEIN INHIBITOR
WO2018094275A1
(en)
2016-11-18
2018-05-24
Tolero Pharmaceuticals, Inc.
Alvocidib prodrugs and their use as protein kinase inhibitors
CA3055132A1
(en)
2017-04-03
2018-10-11
F. Hoffmann-La Roche Ag
Antibodies binding to steap-1
US11497756B2
(en)
2017-09-12
2022-11-15
Sumitomo Pharma Oncology, Inc.
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
WO2019178438A1
(en)
2018-03-15
2019-09-19
Abbvie Inc.
Abbv-621 in combination with anti-cancer agents for the treatment of cancer
WO2019178433A1
(en)
2018-03-15
2019-09-19
Abbvie Inc.
Abbv-621 in combination with anti-cancer agents for the treatment of pancreatic cancer
US11034710B2
(en)
2018-12-04
2021-06-15
Sumitomo Dainippon Pharma Oncology, Inc.
CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
EP3669890A1
(en)
2018-12-18
2020-06-24
Croda International PLC
Filamentous nanoparticles having vaccine adjuvant effect
US11793802B2
(en)
2019-03-20
2023-10-24
Sumitomo Pharma Oncology, Inc.
Treatment of acute myeloid leukemia (AML) with venetoclax failure
CA3148115A1
(en)
2019-08-08
2021-02-11
Laekna Limited
Method of treating cancer
UY39610A
(en)
2021-01-20
2022-08-31
Abbvie Inc
ANTI-EGFR ANTIBODY-DRUG CONJUGATES
Family Cites Families (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4206221A
(en)
*
1979-01-03
1980-06-03
The United States Of America As Represented By The Secretary Of Agriculture
Cephalomannine and its use in treating leukemic tumors
1986
1986-07-17
FR
FR8610400A
patent/FR2601675B1/en
not_active
Expired
1987
1987-07-14
US
US07/073,156
patent/US4814470A/en
not_active
Expired – Lifetime
1987-07-15
ZA
ZA875179A
patent/ZA875179B/en
unknown
1987-07-15
AU
AU75677/87A
patent/AU591309B2/en
not_active
Expired
1987-07-16
ES
ES87401668T
patent/ES2012809B3/en
not_active
Expired – Lifetime
1987-07-16
KR
KR1019870007752A
patent/KR950006153B1/en
not_active
IP Right Cessation
1987-07-16
LU
LU88712C
patent/LU88712I2/en
unknown
1987-07-16
JP
JP62176071A
patent/JPH0651689B2/en
not_active
Expired – Lifetime
1987-07-16
CA
CA000542299A
patent/CA1278304C/en
not_active
Expired – Lifetime
1987-07-16
AT
AT87401668T
patent/ATE49962T1/en
active
1987-07-16
EP
EP87401668A
patent/EP0253738B1/en
not_active
Expired – Lifetime
1987-07-16
DE
DE8787401668T
patent/DE3761562D1/en
not_active
Expired – Lifetime
1990
1990-02-02
GR
GR89400165T
patent/GR3000287T3/en
unknown
1992
1992-06-25
MX
MX9203385A
patent/MX9203385A/en
active
IP Right Grant
1996
1996-03-01
NL
NL960002C
patent/NL960002I2/en
unknown
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU620605B2
(en)
*
1988-03-07
1992-02-20
United States of America, as represented by the Secretary, U.S. Department of Commerce, The
New, water soluble, antineoplastic derivatives of taxol
Also Published As
Publication number
Publication date
KR950006153B1
(en)
1995-06-09
MX9203385A
(en)
1992-07-01
KR880001625A
(en)
1988-04-25
NL960002I2
(en)
1996-11-01
DE3761562D1
(en)
1990-03-08
ES2012809B3
(en)
1990-04-16
CA1278304C
(en)
1990-12-27
US4814470A
(en)
1989-03-21
ATE49962T1
(en)
1990-02-15
ZA875179B
(en)
1988-03-30
GR3000287T3
(en)
1991-03-15
JPH0651689B2
(en)
1994-07-06
EP0253738B1
(en)
1990-01-31
FR2601675B1
(en)
1988-09-23
EP0253738A1
(en)
1988-01-20
NL960002I1
(en)
1996-05-01
JPS6330479A
(en)
1988-02-09
FR2601675A1
(en)
1988-01-22
AU591309B2
(en)
1989-11-30
LU88712I2
(en)
1996-08-23
Similar Documents
Publication
Publication Date
Title
AU591309B2
(en)
1989-11-30
Taxol derivatives, their preparation and pharmaceutical compositions containing them
ES2095432T3
(en)
1997-02-16
DERIVATIVES OF 2,4-TIAZOLIDIN-DIONA, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
AU7026794A
(en)
1995-03-02
Phosphonooxymethyl ethers of taxane derivatives
CA2091360A1
(en)
1992-03-11
Mometasone furoate monohydrate, process for making same and pharmaceutical compositions
IL76457A0
(en)
1986-01-31
Tetralin derivatives,their preparation and pharmaceutical compositions containing them
AU5431390A
(en)
1990-11-16
Novel arylpyridazines, their manufacture, use and medicaments containing them
ES2097297T3
(en)
1997-04-01
ISOQUINOLEIN-5-IL-SULFONAMIDES, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
CA2152771A1
(en)
1996-01-29
7-o-ethers of taxane derivatives
BG102250A
(en)
1999-02-26
The use of marigold-extracted glycosides for the treatment of psoriasis
RO86647A
(en)
1985-04-17
PROCESS FOR THE PREPARATION OF 4 '' – EPIERITROMICINE DERIVATIVES
AU583543B2
(en)
1989-05-04
New adamantanamine derivatives, processes for their preparation and drugs in which they are present
AU611113B2
(en)
1991-06-06
Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
AU632578B2
(en)
1993-01-07
Dibenzo (1,5) dioxocin-5-one derivatives, their use in medicaments and processes for their preparation
ES2007419A6
(en)
1989-06-16
Antitumor anthracycline glycosides, intermediates thereof, and composition and use thereof
HUT49876A
(en)
1989-11-28
Process for producing 6-oxopyridazine derivatives and pharmaceutical compositions comprising same
DE3569732D1
(en)
1989-06-01
Imidazolides, process for obtaining them and their use as intermediates in the synthesis of cytotoxic conjugates
DE3461378D1
(en)
1987-01-08
Rifamycins derivatives and preparation and pharmaceutical compositions thereof
EP0443957A3
(en)
1992-06-17
New 17-spiro substituted steroid compounds, process for their preparation and intermediates of this process, their use as medicines and pharmaceutical preparations containing them
IL93258A0
(en)
1990-11-29
Anthracycline glycoside derivatives,their preparation and pharmaceutical compositions containing them
AU2240388A
(en)
1989-04-06
Azachromane derivatives
IL86479A
(en)
1993-08-18
Substituted vinylcephalosporins, their preparation and pharmaceutical compositions containing them
ES2104295T3
(en)
1997-10-01
CYCLOPEPTIDIC DERIVATIVES OF ANGIOPEPTIN, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
AU578335B2
(en)
1988-10-20
N-substituted aziridine-2-carboxylic acid derivatives
EP0418990A3
(en)
1991-07-03
13-bromo and 13,14-dibromo ergoline, their preparation and their use
EP0377127A3
(en)
1991-10-09
Use of Myricetin-3-O-beta-D glucuronide as medicament
None