AU8061682A

AU8061682A – 3,5-di-tert-butyl-4-hydroxyphenyl substituted heterocyclic compound
– Google Patents

AU8061682A – 3,5-di-tert-butyl-4-hydroxyphenyl substituted heterocyclic compound
– Google Patents
3,5-di-tert-butyl-4-hydroxyphenyl substituted heterocyclic compound

Info

Publication number
AU8061682A

AU8061682A
AU80616/82A
AU8061682A
AU8061682A
AU 8061682 A
AU8061682 A
AU 8061682A
AU 80616/82 A
AU80616/82 A
AU 80616/82A
AU 8061682 A
AU8061682 A
AU 8061682A
AU 8061682 A
AU8061682 A
AU 8061682A
Authority
AU
Australia
Prior art keywords
tert
butyl
heterocyclic compound
substituted heterocyclic
hydroxyphenyl substituted
Prior art date
1981-02-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU80616/82A
Other versions

AU550035B2
(en

Inventor
Hiroshige Homma
Yasuo Isomura
Kazuo Kubo
Shuichi Sakamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Yamanouchi Pharmaceutical Co Ltd

Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1981-02-19
Filing date
1982-02-19
Publication date
1982-08-26

1981-02-19
Priority claimed from JP56023515A
external-priority
patent/JPS57150692A/en

1981-04-21
Priority claimed from JP56059990A
external-priority
patent/JPS57175171A/en

1981-10-02
Priority claimed from JP15701081A
external-priority
patent/JPS5857366A/en

1982-02-19
Application filed by Yamanouchi Pharmaceutical Co Ltd
filed
Critical
Yamanouchi Pharmaceutical Co Ltd

1982-08-26
Publication of AU8061682A
publication
Critical
patent/AU8061682A/en

1986-02-27
Application granted
granted
Critical

1986-02-27
Publication of AU550035B2
publication
Critical
patent/AU550035B2/en

2002-02-19
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D233/70—One oxygen atom

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D233/84—Sulfur atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings

C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

C07D277/24—Radicals substituted by oxygen atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D277/36—Sulfur atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D277/38—Nitrogen atoms

C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 – C07D507/00

C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 – C07D507/00 in which the condensed system contains two hetero rings

C07D513/04—Ortho-condensed systems

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 – C07D507/00

C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 – C07D507/00 in which the condensed system contains two hetero rings

C07D513/06—Peri-condensed systems

AU80616/82A
1981-02-19
1982-02-19
3,5-di-tert-butyl-4-hydroxyphenyl substituted heterocyclic compound

Ceased

AU550035B2
(en)

Applications Claiming Priority (6)

Application Number
Priority Date
Filing Date
Title

JP56-23515

1981-02-19

JP56023515A

JPS57150692A
(en)

1981-02-19
1981-02-19
4-hetero ring-substituted-2,6-di-tert-butyl-phenol derivative

JP56059990A

JPS57175171A
(en)

1981-04-21
1981-04-21
3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compound

JP56-59990

1981-04-21

JP15701081A

JPS5857366A
(en)

1981-10-02
1981-10-02
3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compound

JP56-157010

1981-10-02

Publications (2)

Publication Number
Publication Date

AU8061682A
true

AU8061682A
(en)

1982-08-26

AU550035B2

AU550035B2
(en)

1986-02-27

Family
ID=27284291
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU80616/82A
Ceased

AU550035B2
(en)

1981-02-19
1982-02-19
3,5-di-tert-butyl-4-hydroxyphenyl substituted heterocyclic compound

Country Status (4)

Country
Link

US
(1)

US4636516A
(en)

EP
(2)

EP0059090B1
(en)

AU
(1)

AU550035B2
(en)

DE
(1)

DE3268733D1
(en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4535165A
(en)

*

1981-11-23
1985-08-13
Riker Laboratories, Inc.
Substituted diazoles and thiazoles

US4464536A
(en)

*

1982-11-05
1984-08-07
Riker Laboratories, Inc.
Enamines, pharmaceutical compositions, methods, synthetic processes and intermediates

US4532250A
(en)

*

1983-11-23
1985-07-30
American Hospital Supply Corporation
5-Heteroarylimidazol-2-ones having cardiotonic activity

US5691367A
(en)

*

1985-08-09
1997-11-25
Eli Lilly And Company
Aryl-substituted rhodanine derivatives

GR862081B
(en)

*

1985-08-09
1986-12-24
Lilly Co Eli
Di-t-butylphenol compounds

US5356917A
(en)

*

1985-08-09
1994-10-18
Eli Lilly And Company
Aryl-substituted rhodanine derivatives

US4868183A
(en)

*

1986-07-21
1989-09-19
Otsuka Pharmaceutical Factory, Inc.
N-pyrazinyl substituted P-aminophenols

JPH0615542B2
(en)

*

1986-07-22
1994-03-02
吉富製薬株式会社

Pyrazolopyridine compound

JPS6339868A
(en)

*

1986-08-04
1988-02-20
Otsuka Pharmaceut Factory Inc
Di (lower alkyl) phenol derivative

DE3702756A1
(en)

*

1987-01-30
1988-08-11
Hoechst Ag

5- (3-ALKYL-5-TERT.BUTYL-4-HYDROXYPHENYL) -2- AMINO-6H-1,3,4-THIADIAZINE, METHOD FOR THE PRODUCTION THEREOF THE MEDICINAL PRODUCT CONTAINING IT AND THEIR USE

DE3702758A1
(en)

*

1987-01-30
1988-09-29
Hoechst Ag

SUBSTITUTED 3-PHENYL-7H-THIAZOLO (3,2-B) (1,2,4) TRIAZINE-7-ONE, METHODS FOR THE PRODUCTION THEREOF, THE MEDICINAL PRODUCTS CONTAINING IT AND THEIR USE, AND SOME OF THE PRODUCTS FORMING THE SAME COMPOUNDS INTERMEDIATE PRODUCTS

US5208250A
(en)

*

1988-05-25
1993-05-04
Warner-Lambert Company
Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents

US4959482A
(en)

*

1988-09-26
1990-09-25
Biofor, Ltd.
Pyrrolidinone compounds and pharamaceutical compositions containing same

DE3941438A1
(en)

*

1989-12-15
1991-06-20
Hoechst Ag

NEW 2-SUBSTITUTED 4- (3-ALKYL-5-TERT.-BUTYL-4-HYDROXY-PHENYL) -THIAZOLE, PROCESS FOR THEIR MANUFACTURE, THE MEDICAMENT CONTAINING THEIR AND ITS USE

US5216002A
(en)

*

1989-12-21
1993-06-01
Eli Lilly And Company
Method of treating inflammatory bowel disease

US5234937A
(en)

*

1990-03-27
1993-08-10
Warner-Lambert Company
3,5-di-tertiary-butyl-4-hydroxphenyl oxazolyl methanones and related compounds as antiinflammatory agents

US5086064A
(en)

*

1990-03-27
1992-02-04
Warner-Lambert Company
3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and imidazolyl methanones and related compounds as antiinflammatory agents

US5234939A
(en)

*

1990-03-27
1993-08-10
Warner-Lambert Company
3,5-di-tertiary-butyl-4-hydroxyphenyl imidazolyl methanones and related compounds as antiinflammatory agents

US5240929A
(en)

*

1992-08-03
1993-08-31
Warner-Lambert Company
2-heterocyclic-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents

ZA936492B
(en)

*

1992-09-10
1995-03-02
Lilly Co Eli
Compounds useful as hypoglycemic agents and for treating Alzheimer’s disease.

US6251928B1
(en)

*

1994-03-16
2001-06-26
Eli Lilly And Company
Treatment of alzheimer’s disease employing inhibitors of cathepsin D

US5491159A
(en)

*

1994-08-30
1996-02-13
American Home Products Corporation
2-(3,5-di-tert-butyl-4-hydroxy-phenyl)-oxazoles as anti-atherosclerotic agents

US5552422A
(en)

*

1995-01-11
1996-09-03
Merck Frosst Canada, Inc.
Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents

TW375612B
(en)

*

1995-04-06
1999-12-01
Janssen Pharmaceutica Nv
1,3-dihydro-2H-imidazol-2-one derivatives for the treatment of disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase type IV, preparation thereof and pharmaceutical composition containing the same

US6156748A
(en)

*

1996-10-07
2000-12-05
Eli Lilly And Company
Compounds useful as neuro-protective agents

US6472387B1
(en)

1996-10-07
2002-10-29
Eli Lilly And Company
Methods of using compounds as neuro-protective agents

TR200001750T2
(en)

1997-10-06
2001-01-22
Eli Lilly And Company

New compounds useful as neuroprotective agents.

FR2835254B1
(en)

*

2002-01-25
2006-04-07
Sod Conseils Rech Applic

THIAZOLE DERIVATIVES IN THE TREATMENT OF NEUROLOGICAL DISEASES

US7479507B2
(en)

*

2003-01-14
2009-01-20
Adam Heller
Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs

DE102005021806A1
(en)

*

2005-05-04
2006-11-16
Lancaster Group Gmbh

Use of radical-scavenging substances for the treatment of conditions with increased skin temperature, in particular for antipyretic treatment

US8500395B2
(en)

*

2007-02-15
2013-08-06
Borgwarner Inc.
Turbocharger vane

EP3169323A2
(en)

2014-07-18
2017-05-24
Ohio University
Imidazole and thiazole compositions for modifying biological signaling

Family Cites Families (6)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3578671A
(en)

*

1967-11-06
1971-05-11
Wyeth John & Brother Ltd
Oxazoles

US4072689A
(en)

*

1973-02-22
1978-02-07
Gruppo Lepetit S.P.A.
Monoamino 2,4,5-trisubstituted oxazoles

US4044019A
(en)

*

1974-05-14
1977-08-23
Ciba-Geigy Corporation
Hydroxyphenylated hydantoins

LU77703A1
(en)

*

1977-07-07
1979-03-26
Ciba Geigy Ag

METHOD FOR PRODUCING BICYCLIC THIA-DIAZA COMPOUNDS

US4104400A
(en)

*

1977-07-08
1978-08-01
E. R. Squibb & Sons, Inc.
Imidazo(2,1-b)thiazole derivatives, compositions containing same, and method of treating helminthiasis

PL221188A1
(en)

*

1979-01-05
1980-12-01
Ciba Geigy Ag

1982

1982-02-11
US
US06/347,982
patent/US4636516A/en
not_active
Expired – Fee Related

1982-02-19
EP
EP82300861A
patent/EP0059090B1/en
not_active
Expired

1982-02-19
AU
AU80616/82A
patent/AU550035B2/en
not_active
Ceased

1982-02-19
EP
EP85200531A
patent/EP0164765A1/en
not_active
Withdrawn

1982-02-19
DE
DE8282300861T
patent/DE3268733D1/en
not_active
Expired

Also Published As

Publication number
Publication date

EP0059090A1
(en)

1982-09-01

US4636516A
(en)

1987-01-13

DE3268733D1
(en)

1986-03-13

AU550035B2
(en)

1986-02-27

EP0164765A1
(en)

1985-12-18

EP0059090B1
(en)

1986-01-29

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