AU1214383A – Pyridine derivatives
– Google Patents
AU1214383A – Pyridine derivatives
– Google Patents
Pyridine derivatives
Info
Publication number
AU1214383A
AU1214383A
AU12143/83A
AU1214383A
AU1214383A
AU 1214383 A
AU1214383 A
AU 1214383A
AU 12143/83 A
AU12143/83 A
AU 12143/83A
AU 1214383 A
AU1214383 A
AU 1214383A
AU 1214383 A
AU1214383 A
AU 1214383A
Authority
AU
Australia
Prior art keywords
radical
oxygen atom
optionally substituted
aryl
optionally interrupted
Prior art date
1982-03-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU12143/83A
Inventor
Andreas Knorr
Horst Meyer
Egbert Wehinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1982-03-10
Filing date
1983-03-08
Publication date
1983-09-15
1983-03-08
Application filed by Bayer AG
filed
Critical
Bayer AG
1983-09-15
Publication of AU1214383A
publication
Critical
patent/AU1214383A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
C07D211/86—Oxygen atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P11/00—Drugs for disorders of the respiratory system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P13/00—Drugs for disorders of the urinary system
A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P15/00—Drugs for genital or sexual disorders; Contraceptives
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer’s disease or other forms of dementia
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/06—Antiarrhythmics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/08—Vasodilators for multiple indications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/12—Antihypertensives
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
Abstract
Compounds of the formula
AU12143/83A
1982-03-10
1983-03-08
Pyridine derivatives
Abandoned
AU1214383A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE32086288
1982-03-10
DE19823208628
DE3208628A1
(en)
1982-03-10
1982-03-10
NEW COMPOUNDS, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
Publications (1)
Publication Number
Publication Date
AU1214383A
true
AU1214383A
(en)
1983-09-15
Family
ID=6157837
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU12143/83A
Abandoned
AU1214383A
(en)
1982-03-10
1983-03-08
Pyridine derivatives
Country Status (17)
Country
Link
US
(1)
US4622332A
(en)
EP
(1)
EP0088276B1
(en)
JP
(1)
JPS58164575A
(en)
KR
(1)
KR840004074A
(en)
AT
(1)
ATE19513T1
(en)
AU
(1)
AU1214383A
(en)
CA
(1)
CA1239401A
(en)
DE
(2)
DE3208628A1
(en)
DK
(1)
DK114783A
(en)
ES
(1)
ES8401466A1
(en)
FI
(1)
FI830776L
(en)
GR
(1)
GR78508B
(en)
IL
(1)
IL68075A0
(en)
NO
(1)
NO830612L
(en)
PH
(1)
PH20468A
(en)
PT
(1)
PT76316B
(en)
ZA
(1)
ZA831633B
(en)
Cited By (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU571316B2
(en)
*
1984-03-27
1988-04-14
Laboratorios Delagrange
3-phenyl-1,4-dihydropyridine derivatives
AU588656B2
(en)
*
1985-12-13
1989-09-21
Bayer Aktiengesellschaft
New fluorine-containing 1,4-dihydropyridines, process for their preparation and their use as medicaments
AU610753B2
(en)
*
1986-04-02
1991-05-23
Fournier Industrie Et Sante
Asymmetrical ester derivatives of 1,4-dihydropyridine-3, 5-dicarboxylic acid
AU708956B2
(en)
*
1995-08-14
1999-08-19
Bayer Aktiengesellschaft
Substituted 4H-pyrans
Families Citing this family (38)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0080220B1
(en)
*
1981-11-17
1986-02-19
FISONS plc
Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
US4414213A
(en)
*
1982-03-22
1983-11-08
Mead Johnson & Company
Dihydropyridyl cyclic imidate esters and their pharmaceutical use
US4656181A
(en)
*
1982-11-24
1987-04-07
Cermol S.A.
Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
WO1985000169A1
(en)
*
1983-06-21
1985-01-17
Sandoz Ag
1,4-dihydropyridine derivatives, production thereof and pharmaceutical preparations containing them
JPS60120861A
(en)
*
1983-12-02
1985-06-28
Otsuka Pharmaceut Co Ltd
Dihydropyridine derivative
DE4342196A1
(en)
*
1993-12-10
1995-06-14
Bayer Ag
New 4-phenyl-substituted 1,4-dihydropyridines
JPS60156671A
(en)
*
1984-01-25
1985-08-16
Yamanouchi Pharmaceut Co Ltd
Dihydropyridine derivative and its preparation
US4672068A
(en)
*
1984-05-04
1987-06-09
Fujirebio Kabushiki Kaisha
Antihypertensive 1,4-dihydropyridines having a conjugated ester
FR2568773B1
(en)
*
1984-08-10
1989-03-03
Sandoz Lab
NEW NASAL ADMINISTRATIVE PHARMACEUTICAL COMPOSITIONS
AT381306B
(en)
*
1984-08-28
1986-09-25
Bayer Ag
METHOD FOR PRODUCING UNSYMMETRICAL 1,4-DIHYDROPYRIDINE DICARBONIC ACID ESTERS
NO854021L
(en)
*
1984-10-26
1986-04-28
Bayer Ag
1,4-DIHYDROPYRIDINE HYDROXYAMINES AND PROCEDURES FOR PREPARING THEREOF.
HUT39179A
(en)
*
1984-12-10
1986-08-28
Sandoz Ag
Process for production of derivatives of 1,4-dihydro-piridin
US4833150A
(en)
*
1985-03-14
1989-05-23
Nelson Research & Development Co.
1,4-dihydropyridines
US4659717A
(en)
*
1985-08-21
1987-04-21
Eli Lilly And Company
Dihydropyridines useful in the treatment of angina and stroke
US4735956A
(en)
*
1985-09-13
1988-04-05
Merck & Co., Inc.
Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers
JPS62174050A
(en)
*
1985-10-21
1987-07-30
Nippon Shoji Kk
3-aminocarbonyl-1, 4-dihydropyridine-5-carboxylic acid derivative, production thereof and drug composition
US4771057A
(en)
*
1986-02-03
1988-09-13
University Of Alberta
Reduced pyridyl derivatives with cardiovascular regulating properties
US4849436A
(en)
*
1986-03-11
1989-07-18
Nelson Research & Development Co.
1,4-dihydropyridines
US4814455A
(en)
*
1986-04-16
1989-03-21
Bristol-Myers Company
Dihydro-3,5-dicarboxylates
US4769382A
(en)
*
1986-09-30
1988-09-06
Institut Organischeskogo Sinteza Leningradsky Nauchno-Issledovatelsky Institut
Preparation for preventing and treatment of skin radiation burn lesions
DE3724909A1
(en)
*
1987-07-28
1989-02-09
Bayer Ag
NEW SUBSTITUTED NITRO-DIHYDROPYRIDINE, METHOD FOR THEIR PRODUCTION AND THEIR USE
US5470982A
(en)
*
1988-01-20
1995-11-28
Bayer Aktiengesellschaft
Disubstituted pyridines
JPH01151557A
(en)
*
1988-11-15
1989-06-14
Otsuka Pharmaceut Co Ltd
Hypotensor
JPH02149563A
(en)
*
1988-11-30
1990-06-08
Nisshin Flour Milling Co Ltd
Production of 1,4-dihydropyridine derivative containing 2-haloethoxycarbonyl group
DK0595164T3
(en)
*
1992-10-30
1997-05-26
Bayer Ag
4-Heterocyclophenyl-substituted dihydropyridines
DE4236707A1
(en)
*
1992-10-30
1994-05-05
Bayer Ag
4-heterocyclyl substituted dihydropyridines
US6001857A
(en)
*
1992-10-30
1999-12-14
Bayer Aktiengesellschaft
Heterocyclyl substituted dihydropyridines
DE4342193A1
(en)
*
1993-12-10
1995-06-14
Bayer Ag
Aryl substituted alkoxycarbonyl-1,4-dihydropyridine-5-carboxylic acid esters
ATE234286T1
(en)
1993-12-10
2003-03-15
Bayer Ag
PHENYL-SUBSTITUTED 1,4-DIHYDROPYRIDINES WITH CEREBRAL ACTIVITY
EE03192B1
(en)
*
1993-12-10
1999-06-15
Bayer Aktiengesellschaft
Isopropyl (2-methoxyethyl) -4- (2-chloro-3-cyanophenyl) -1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate, its enantiomers and intermediate, methods for their preparation and use
DE4429786A1
(en)
*
1994-08-23
1996-02-29
Bayer Ag
Use of substituted 6-amino-4H-pyrans
DE19529859A1
(en)
*
1995-08-14
1997-02-20
Bayer Ag
Use of acyl-substituted aminopyrans
US5977369A
(en)
*
1995-12-28
1999-11-02
Napp Technologies, Inc.
Process to prepare dihydropyridine and derivatives thereof
IT1283793B1
(en)
*
1996-08-23
1998-04-30
Lusochimica Spa
DIHYDROPYRIDINE PREPARATION PROCESS
US6537504B1
(en)
1998-04-06
2003-03-25
Li Young
Method and apparatus for concurrent and sequential multi-step reactions for producing a plurality of different chemical compounds
US6538004B2
(en)
2000-03-03
2003-03-25
Abbott Laboratories
Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
DK1259510T3
(en)
*
2000-03-03
2004-10-04
Abbott Lab
Tricyclic dihydropyrazolone and tricyclic dihydroxiozolone, which open potassium channels
CN105669532B
(en)
*
2014-12-03
2018-11-02
广州市恒诺康医药科技有限公司
Nimodipine soluble derivative and its preparation method and application
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Title
DE2117571C3
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1971-04-10
1979-10-11
Bayer Ag, 5090 Leverkusen
Asymmetrical 1,4-dihydropyridine-33-dicarboxylic acid esters, process for their preparation and their use as pharmaceuticals
DE2117573C3
(en)
*
1971-04-10
1978-07-27
Bayer Ag, 5090 Leverkusen
Process for the preparation of asymmetrical 1,4-dihydropyridine-3,5dicarboxylic acid esters, and their use as medicaments
US3932645A
(en)
*
1971-04-10
1976-01-13
Farbenfabriken Bayer Ag
Pharmaceutical compositions containing unsymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid
DE2210672C3
(en)
*
1972-03-06
1980-03-20
Bayer Ag, 5090 Leverkusen
N-substituted asymmetrical 1 ^ -dihydropyridine-S ^ -dicarboxylic acid esters, process for their preparation and their use as medicaments
DE2210674C3
(en)
*
1972-03-06
1981-09-24
Bayer Ag, 5090 Leverkusen
2-Amino-6-methyl-1,4-dihydropyridines, process for their preparation and pharmaceuticals containing them
DE2235406C3
(en)
*
1972-07-19
1982-01-07
Bayer Ag, 5090 Leverkusen
2-Amino-4H-pyrans, process for their preparation and their use as pharmaceuticals
DE2650013C3
(en)
*
1976-10-30
1981-04-02
Bayer Ag, 5090 Leverkusen
1,4-Dihydro-2,6-dimethyl-4- (3-nitrophenyl) -3,5-pyridinedicarboxylic acid isopropyl (2-propoxy-ethyl) ester, process for its preparation and medicinal products containing it
DE2659665A1
(en)
*
1976-12-30
1978-07-13
Nattermann A & Cie
NEW 1,4-DIHYDROPYRIDINE DERIVATIVES
FI64938C
(en)
*
1977-06-20
1984-02-10
Sandoz Ag
PROCEDURE FOR THE FRAMEWORK OF THERAPEUTIC THERAPEUTIC BENSOX A- AND OX BENZOTIADIAZOLYL-1,4-DIHYDROPYRID DERIVATIVES
SU740768A1
(en)
*
1977-11-21
1980-06-15
Институт Органического Синтеза Ан Латвийской Сср
Method of preparing 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid esters
SU725406A1
(en)
*
1978-08-08
1981-07-30
Ордена Трудового Красного Знамениинститут Органического Синтеза Ah Латвий-Ской Ccp
Esters of 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid possessing antimetastatic activity
JPS5527054A
(en)
*
1978-08-15
1980-02-26
Gen Foods Corp
Adsorption method
US4307103A
(en)
*
1978-09-08
1981-12-22
Fujisawa Pharmaceutical Co., Ltd.
Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
DE2847236A1
(en)
*
1978-10-31
1980-05-14
Bayer Ag
NEW DIHYDROPYRIDINE WITH SUBSTITUTED ESTER GROUPS, MORE PROCEDURES FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
US4258042A
(en)
*
1980-04-11
1981-03-24
Usv Pharmaceutical Corporation
Antihypertensive pyridines and compositions
DE3018259A1
(en)
*
1980-05-13
1981-11-19
Bayer Ag, 5090 Leverkusen
1,4-DIHYDROPYRIDINE WITH DIFFERENT SUBSTITUENTS IN 2- AND 6-POSITIONS, METHODS FOR THEIR PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS
DE3022030A1
(en)
*
1980-06-12
1981-12-17
Bayer Ag, 5090 Leverkusen
4-THIAZOLE or 4-IMIDAZOLE-SUBSTITUTED, 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM
DE3042769A1
(en)
*
1980-11-13
1982-06-09
Bayer Ag, 5090 Leverkusen
C-3 LINKED 1,4-DIHYDROPYRIDINE, THEIR USE IN MEDICINAL PRODUCTS AND METHOD FOR THE PRODUCTION THEREOF
1982
1982-03-10
DE
DE19823208628
patent/DE3208628A1/en
not_active
Withdrawn
1983
1983-02-21
AT
AT83101626T
patent/ATE19513T1/en
not_active
IP Right Cessation
1983-02-21
EP
EP83101626A
patent/EP0088276B1/en
not_active
Expired
1983-02-21
DE
DE8383101626T
patent/DE3363244D1/en
not_active
Expired
1983-02-22
US
US06/468,621
patent/US4622332A/en
not_active
Expired – Fee Related
1983-02-22
NO
NO830612A
patent/NO830612L/en
unknown
1983-03-01
PT
PT76316A
patent/PT76316B/en
unknown
1983-03-07
IL
IL68075A
patent/IL68075A0/en
unknown
1983-03-08
FI
FI830776A
patent/FI830776L/en
not_active
Application Discontinuation
1983-03-08
GR
GR70727A
patent/GR78508B/el
unknown
1983-03-08
CA
CA000423079A
patent/CA1239401A/en
not_active
Expired
1983-03-08
AU
AU12143/83A
patent/AU1214383A/en
not_active
Abandoned
1983-03-09
JP
JP58037579A
patent/JPS58164575A/en
active
Pending
1983-03-09
ES
ES520441A
patent/ES8401466A1/en
not_active
Expired
1983-03-09
ZA
ZA831633A
patent/ZA831633B/en
unknown
1983-03-09
KR
KR1019830000953A
patent/KR840004074A/en
not_active
Application Discontinuation
1983-03-09
PH
PH28620A
patent/PH20468A/en
unknown
1983-03-09
DK
DK114783A
patent/DK114783A/en
not_active
Application Discontinuation
Cited By (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU571316B2
(en)
*
1984-03-27
1988-04-14
Laboratorios Delagrange
3-phenyl-1,4-dihydropyridine derivatives
AU588656B2
(en)
*
1985-12-13
1989-09-21
Bayer Aktiengesellschaft
New fluorine-containing 1,4-dihydropyridines, process for their preparation and their use as medicaments
AU610753B2
(en)
*
1986-04-02
1991-05-23
Fournier Industrie Et Sante
Asymmetrical ester derivatives of 1,4-dihydropyridine-3, 5-dicarboxylic acid
AU708956B2
(en)
*
1995-08-14
1999-08-19
Bayer Aktiengesellschaft
Substituted 4H-pyrans
Also Published As
Publication number
Publication date
ES520441A0
(en)
1983-12-16
FI830776L
(en)
1983-09-11
NO830612L
(en)
1983-09-12
JPS58164575A
(en)
1983-09-29
KR840004074A
(en)
1984-10-06
US4622332A
(en)
1986-11-11
GR78508B
(en)
1984-09-27
ATE19513T1
(en)
1986-05-15
PH20468A
(en)
1987-01-14
FI830776A0
(en)
1983-03-08
DK114783A
(en)
1983-09-11
PT76316A
(en)
1983-04-01
PT76316B
(en)
1985-11-25
EP0088276B1
(en)
1986-04-30
EP0088276A1
(en)
1983-09-14
ES8401466A1
(en)
1983-12-16
DE3208628A1
(en)
1983-09-22
CA1239401A
(en)
1988-07-19
ZA831633B
(en)
1983-12-28
IL68075A0
(en)
1983-06-15
DK114783D0
(en)
1983-03-09
DE3363244D1
(en)
1986-06-05
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