AU2043388A

AU2043388A – Cyclic peptides as promoters of absorption on administration onto the mucosa
– Google Patents

AU2043388A – Cyclic peptides as promoters of absorption on administration onto the mucosa
– Google Patents
Cyclic peptides as promoters of absorption on administration onto the mucosa

Info

Publication number
AU2043388A

AU2043388A
AU20433/88A
AU2043388A
AU2043388A
AU 2043388 A
AU2043388 A
AU 2043388A
AU 20433/88 A
AU20433/88 A
AU 20433/88A
AU 2043388 A
AU2043388 A
AU 2043388A
AU 2043388 A
AU2043388 A
AU 2043388A
Authority
AU
Australia
Prior art keywords
denotes
amino acid
absorption
mucosa
promoters
Prior art date
1987-08-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU20433/88A
Other versions

AU608878B2
(en

Inventor
Hans Peter Merkle
Susanne Raehs
Jurgen Kurt Sandow
Rainer Schmiedel
Klaus Wirth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1987-08-07
Filing date
1988-08-05
Publication date
1989-04-20

1988-08-05
Application filed by Hoechst AG
filed
Critical
Hoechst AG

1989-04-20
Publication of AU2043388A
publication
Critical
patent/AU2043388A/en

1991-04-18
Application granted
granted
Critical

1991-04-18
Publication of AU608878B2
publication
Critical
patent/AU608878B2/en

2008-08-05
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates

A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite

A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The invention relates to the use of aids of the general formula in which B denotes a basic amino acid, A/B denotes an acidic or basic amino acid, X denotes a neutral and hydrophilic amino acid, L denotes a lipophilic neutral amino acid, and R denotes hydrogen or an acyl radical, or the physiologically tolerated salts thereof, for promoting the absorption of peptides and proteins on administration onto the mocosa, as well as to pharmaceutical compositions which contain a pharmacologically effective amount of one or more peptides or proteins as well as an aid of the abovementioned formula.

AU20433/88A
1987-08-07
1988-08-05
Cyclic peptides as promoters of absorption on administration onto the mucosa

Ceased

AU608878B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

DE3726324

1987-08-07

DE19873726324

DE3726324A1
(en)

1987-08-07
1987-08-07

CYCLOPEPTIDE AS RESORPTION FOLDER IN APPLICATION TO THE MEAT

Publications (2)

Publication Number
Publication Date

AU2043388A
true

AU2043388A
(en)

1989-04-20

AU608878B2

AU608878B2
(en)

1991-04-18

Family
ID=6333298
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU20433/88A
Ceased

AU608878B2
(en)

1987-08-07
1988-08-05
Cyclic peptides as promoters of absorption on administration onto the mucosa

Country Status (19)

Country
Link

US
(1)

US5091365A
(en)

EP
(1)

EP0302466B1
(en)

JP
(1)

JP2764930B2
(en)

KR
(1)

KR970004039B1
(en)

AT
(1)

ATE69556T1
(en)

AU
(1)

AU608878B2
(en)

CA
(1)

CA1331131C
(en)

DE
(2)

DE3726324A1
(en)

DK
(1)

DK168273B1
(en)

ES
(1)

ES2038725T3
(en)

FI
(1)

FI883643A
(en)

GR
(1)

GR3003733T3
(en)

HU
(1)

HU199301B
(en)

IE
(1)

IE60871B1
(en)

IL
(1)

IL87362A0
(en)

NO
(1)

NO179094C
(en)

NZ
(1)

NZ225715A
(en)

PT
(1)

PT88192B
(en)

ZA
(1)

ZA885724B
(en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

TW274552B
(en)

*

1992-05-26
1996-04-21
Hoechst Ag

PT710243E
(en)

*

1993-06-29
2000-11-30
Ferring Bv

IMPROVED SYNTHESIS OF CYCLIC PEPTIDOS.

US5767068A
(en)

*

1997-02-13
1998-06-16
Pathogenesis Corporation
Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections

IT1294191B1
(en)

*

1997-09-05
1999-03-22
Alfa Wassermann Spa
Composition for treating osteoporosis, Paget’s disease or hypercalcemia, comprises calcitonin dissolved in acidic sodium chloride solution

KR100611559B1
(en)

*

1998-05-08
2007-04-25
동아제약주식회사

Intranasal pharmaceutical compositions containing calcitonin

SE514606C2
(en)

*

1998-08-26
2001-03-19
Laekartjaenster I Vaestsverige

Drugs containing GnRH analogues for the treatment of schizophrenia

DE10014007A1
(en)

*

2000-03-22
2001-10-11
Strathmann Ag & Co
Medicament for pulmonary or intranasal administration, useful for treating withdrawal symptoms, sleeping disorders or stress, comprises delta-sleep inducing peptide

US20020141970A1
(en)

*

2001-03-05
2002-10-03
Pettit Dean K.
Stable aqueous solutions of granulocyte macrophage colony-stimulating factor

US7812120B2
(en)

2003-03-21
2010-10-12
Par Pharmaceutical, Inc.
Nasal calcitonin formulations containing chlorobutanol

EP3445778B1
(en)

2016-04-19
2020-07-15
Griffon Pharmaceuticals International SA
Pegylated bioactive peptides and uses thereof

WO2020196315A1
(en)

*

2019-03-25
2020-10-01
国立大学法人筑波大学
Promotor for permeation into cell layer, composition for facilitating drug agent absorption, and pharmaceutical composition

Family Cites Families (10)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE3171774D1
(en)

*

1980-03-31
1985-09-19
Teijin Ltd
Pharmaceutical composition for intrarectal administration, and suppository prepared therefrom

US4900730A
(en)

*

1981-01-14
1990-02-13
Toyo Jozo Co., Ltd.
Preparation which promotes the absorption of peptides

FR2509175B1
(en)

*

1981-03-06
1987-01-16
Toyo Jozo Kk

THERAPEUTIC PREPARATION HAVING EXCELLENT ABSORPTION PROPERTIES

JPS58140026A
(en)

*

1982-01-14
1983-08-19
Toyo Jozo Co Ltd
Pharmaceutical having improved absorbability

US4568665A
(en)

1982-06-25
1986-02-04
Mitchell David C
Protein compounds

JPS59163313A
(en)

*

1983-03-09
1984-09-14
Teijin Ltd
Peptide hormone composition for nasal administration

CA1249968A
(en)

*

1984-04-05
1989-02-14
Kazuo Kigasawa
Ointment base

US4537772A
(en)

*

1984-05-02
1985-08-27
Merck & Co., Inc.
Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines

JPS6160620A
(en)

*

1984-09-03
1986-03-28
Teijin Ltd
Pharmaceutical composition containing pyroglutamic acid ester

DE3532074A1
(en)

*

1985-09-09
1987-03-12
Berlin Chemie Veb

RESORPTION AGENT FOR BIOLOGICALLY ACTIVE PEPTIDES

1987

1987-08-07
DE
DE19873726324
patent/DE3726324A1/en
not_active
Withdrawn

1988

1988-08-03
DE
DE8888112611T
patent/DE3866307D1/en
not_active
Expired – Lifetime

1988-08-03
AT
AT88112611T
patent/ATE69556T1/en
not_active
IP Right Cessation

1988-08-03
EP
EP88112611A
patent/EP0302466B1/en
not_active
Expired – Lifetime

1988-08-03
ES
ES198888112611T
patent/ES2038725T3/en
not_active
Expired – Lifetime

1988-08-04
NO
NO883468A
patent/NO179094C/en
not_active
IP Right Cessation

1988-08-04
FI
FI883643A
patent/FI883643A/en
not_active
Application Discontinuation

1988-08-04
PT
PT88192A
patent/PT88192B/en
not_active
IP Right Cessation

1988-08-04
ZA
ZA885724A
patent/ZA885724B/en
unknown

1988-08-05
IL
IL87362A
patent/IL87362A0/en
not_active
IP Right Cessation

1988-08-05
CA
CA000573914A
patent/CA1331131C/en
not_active
Expired – Lifetime

1988-08-05
US
US07/228,651
patent/US5091365A/en
not_active
Expired – Lifetime

1988-08-05
AU
AU20433/88A
patent/AU608878B2/en
not_active
Ceased

1988-08-05
JP
JP63194741A
patent/JP2764930B2/en
not_active
Expired – Lifetime

1988-08-05
DK
DK440888A
patent/DK168273B1/en
not_active
IP Right Cessation

1988-08-05
HU
HU884101A
patent/HU199301B/en
not_active
IP Right Cessation

1988-08-05
IE
IE240888A
patent/IE60871B1/en
not_active
IP Right Cessation

1988-08-05
NZ
NZ225715A
patent/NZ225715A/en
unknown

1988-08-06
KR
KR1019880010046A
patent/KR970004039B1/en
not_active
IP Right Cessation

1992

1992-02-06
GR
GR910402039T
patent/GR3003733T3/el
unknown

Also Published As

Publication number
Publication date

KR890003409A
(en)

1989-04-14

DE3726324A1
(en)

1989-02-16

JPS6466128A
(en)

1989-03-13

NZ225715A
(en)

1991-02-26

HU199301B
(en)

1990-02-28

PT88192B
(en)

1995-03-01

JP2764930B2
(en)

1998-06-11

IE882408L
(en)

1989-02-07

EP0302466B1
(en)

1991-11-21

ATE69556T1
(en)

1991-12-15

AU608878B2
(en)

1991-04-18

DE3866307D1
(en)

1992-01-02

EP0302466A1
(en)

1989-02-08

FI883643A0
(en)

1988-08-04

NO883468L
(en)

1989-02-08

DK440888D0
(en)

1988-08-05

ZA885724B
(en)

1989-04-26

KR970004039B1
(en)

1997-03-24

IL87362A0
(en)

1989-01-31

FI883643A
(en)

1989-02-08

PT88192A
(en)

1989-06-30

NO179094B
(en)

1996-04-29

CA1331131C
(en)

1994-08-02

DK168273B1
(en)

1994-03-07

GR3003733T3
(en)

1993-03-16

DK440888A
(en)

1989-02-08

HUT47599A
(en)

1989-03-28

NO883468D0
(en)

1988-08-04

ES2038725T3
(en)

1993-08-01

NO179094C
(en)

1996-08-07

IE60871B1
(en)

1994-08-24

US5091365A
(en)

1992-02-25

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Legal Events

Date
Code
Title
Description

2002-03-07
MK14
Patent ceased section 143(a) (annual fees not paid) or expired

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