AU2094397A – New arylglycinamide derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
– Google Patents
AU2094397A – New arylglycinamide derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
– Google Patents
New arylglycinamide derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
Info
Publication number
AU2094397A
AU2094397A
AU20943/97A
AU2094397A
AU2094397A
AU 2094397 A
AU2094397 A
AU 2094397A
AU 20943/97 A
AU20943/97 A
AU 20943/97A
AU 2094397 A
AU2094397 A
AU 2094397A
AU 2094397 A
AU2094397 A
AU 2094397A
Authority
AU
Australia
Prior art keywords
preparing
compounds
processes
pharmaceutical compositions
compositions containing
Prior art date
1996-03-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU20943/97A
Other versions
AU718584B2
(en
Inventor
Horst Dollinger
Franz Esser
Birgit Jung
Gerd Schnorrenberg
Kurt Schromm
Georg Speck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1996-03-06
Filing date
1997-03-03
Publication date
1997-09-22
1997-03-03
Application filed by BOEHRINGER INGELHEIM PHARMA, Boehringer Ingelheim Pharma GmbH and Co KG
filed
Critical
BOEHRINGER INGELHEIM PHARMA
1997-09-22
Publication of AU2094397A
publication
Critical
patent/AU2094397A/en
2000-04-13
Application granted
granted
Critical
2000-04-13
Publication of AU718584B2
publication
Critical
patent/AU718584B2/en
2017-03-03
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 – C07D219/00
C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 – C07D219/00 condensed with carbocyclic rings or ring systems
C07D221/04—Ortho- or peri-condensed ring systems
C07D221/06—Ring systems of three rings
C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P11/00—Drugs for disorders of the respiratory system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P11/00—Drugs for disorders of the respiratory system
A61P11/06—Antiasthmatics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P17/00—Drugs for dermatological disorders
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P17/00—Drugs for dermatological disorders
A61P17/04—Antipruritics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P17/00—Drugs for dermatological disorders
A61P17/06—Antipsoriatics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P19/00—Drugs for skeletal disorders
A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/06—Antimigraine agents
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/08—Antiepileptics; Anticonvulsants
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
A61P25/16—Anti-Parkinson drugs
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/24—Antidepressants
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer’s disease or other forms of dementia
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P27/00—Drugs for disorders of the senses
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A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P27/00—Drugs for disorders of the senses
A61P27/02—Ophthalmic agents
A61P27/04—Artificial tears; Irrigation solutions
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P37/00—Drugs for immunological or allergic disorders
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P37/00—Drugs for immunological or allergic disorders
A61P37/08—Antiallergic agents
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D211/40—Oxygen atoms
C07D211/44—Oxygen atoms attached in position 4
C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D211/56—Nitrogen atoms
C07D211/58—Nitrogen atoms attached in position 4
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D213/72—Nitrogen atoms
C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
C07D239/32—One oxygen, sulfur or nitrogen atom
C07D239/42—One nitrogen atom
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
C07D295/182—Radicals derived from carboxylic acids
C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
C07D295/28—Nitrogen atoms
C07D295/30—Nitrogen atoms non-acylated
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
AU20943/97A
1996-03-06
1997-03-03
New arylglycinamide derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
Ceased
AU718584B2
(en)
Applications Claiming Priority (3)
Application Number
Priority Date
Filing Date
Title
DE19608665A
DE19608665A1
(en)
1996-03-06
1996-03-06
Novel arylglycine amide derivatives, processes for their preparation and pharmaceutical compositions containing them
DE19608665
1996-03-06
PCT/EP1997/001038
WO1997032865A1
(en)
1996-03-06
1997-03-03
Novel aryl glycinamide derivatives, method of producing said derivatives and pharmaceutical compositions containing these compounds
Publications (2)
Publication Number
Publication Date
AU2094397A
true
AU2094397A
(en)
1997-09-22
AU718584B2
AU718584B2
(en)
2000-04-13
Family
ID=7787400
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU20943/97A
Ceased
AU718584B2
(en)
1996-03-06
1997-03-03
New arylglycinamide derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
Country Status (33)
Country
Link
US
(2)
US6498162B1
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EP
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DE19824470A1
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1998-05-30
1999-12-02
Boehringer Ingelheim Pharma
Novel neurokine antagonists, processes for their preparation and pharmaceutical compositions containing these compounds
GB9923748D0
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1999-10-07
1999-12-08
Glaxo Group Ltd
Chemical compounds
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1999-10-07
2007-11-13
Smithkline Beecham Corporation
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GB0025354D0
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2000-10-17
2000-11-29
Glaxo Group Ltd
Chemical compounds
US6664253B2
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2000-10-17
2003-12-16
Boehringer Ingelheim Pharma Kg
Neurokinin antagonists
DE10051320A1
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*
2000-10-17
2002-04-25
Boehringer Ingelheim Pharma
New 2-(4-amino-piperidin-1-yl)-2-aryl-N-(phenylalkyl)-acetamides, are neurokinin antagonists having a long duration of action, useful e.g. for treating allergic, inflammatory or central nervous system diseases
US6747044B2
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2000-10-17
2004-06-08
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2000-10-31
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Boehringer Ingelheim Pharma Gmbh & Co. Kg
Pharmaceutical compositions based on anticholinergics and additional active ingredients
US6620438B2
(en)
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2001-03-08
2003-09-16
Boehringer Ingelheim Pharma Kg
Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists
DE10111058A1
(en)
*
2001-03-08
2002-09-12
Boehringer Ingelheim Pharma
New drug compositions based on anticholinergics and NK¶1¶ receptor antagonists
GB0108594D0
(en)
*
2001-04-05
2001-05-23
Glaxo Group Ltd
Chemical compounds
EP1295599A1
(en)
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2001-09-21
2003-03-26
Boehringer Ingelheim International GmbH
Method for the treatment of prevention of atopic dermatitis
EP1472222A1
(en)
2002-02-08
2004-11-03
Glaxo Group Limited
Piperidylcarboxamide derivatives and their use in the treatment of tachykinim-mediated diseases
GB0203020D0
(en)
2002-02-08
2002-03-27
Glaxo Group Ltd
Chemical compounds
GB0203022D0
(en)
2002-02-08
2002-03-27
Glaxo Group Ltd
Chemical compounds
DE10230750A1
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2002-07-09
2004-01-22
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New drug compositions based on new anticholonergics and NK1 receptor antagonists
JP2007532638A
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2004-04-14
2007-11-15
アストラゼネカ・アクチエボラーグ
Arylglycinamide derivatives and their use as NK1 antagonists and serotonin reuptake inhibitors
US20060035893A1
(en)
2004-08-07
2006-02-16
Boehringer Ingelheim International Gmbh
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1
(en)
2004-12-24
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Boehringer Ingelheim Int
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University Of The Pacific
Piperazinylpyrimidine analogues as protein kinase inhibitors
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2011-07-04
2017-10-10
Irbm Science Park S.P.A.
Treatment of corneal neovascularization
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2018-08-14
Ethicon Llc
Surgical instrument system comprising an inspection station
JP6984923B2
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2017-09-19
2021-12-22
イミュンワーク インク.Immunwork Inc.
Pharmaceutical constructs with enhanced binding affinity for albumin
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2018-02-26
2020-11-10
圣拉斐尔医院有限公司
NK-1 antagonists for the treatment of ocular pain
WO2021180885A1
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2021-09-16
Ospedale San Raffaele S.R.L.
Treatment of stem cell deficiency
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Title
US3033869A
(en)
*
1962-05-08
A-piperidino-a-phenyl-n-cyclohexyl
DE19519245C2
(en)
*
1995-04-14
2003-04-30
Boehringer Ingelheim Kg
Novel arylglycine amide derivatives, processes for their preparation and pharmaceutical compositions containing them
US6620438B2
(en)
*
2001-03-08
2003-09-16
Boehringer Ingelheim Pharma Kg
Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists
1996
1996-03-06
DE
DE19608665A
patent/DE19608665A1/en
not_active
Withdrawn
1997
1997-03-03
HU
HU9901823A
patent/HU9901823A3/en
unknown
1997-03-03
TR
TR1998/01734T
patent/TR199801734T2/en
unknown
1997-03-03
WO
PCT/EP1997/001038
patent/WO1997032865A1/en
not_active
Application Discontinuation
1997-03-03
AT
AT97906150T
patent/ATE219069T1/en
active
1997-03-03
EA
EA199800794A
patent/EA002201B1/en
not_active
IP Right Cessation
1997-03-03
UA
UA98105275A
patent/UA50762C2/en
unknown
1997-03-03
KR
KR1019980707089A
patent/KR19990087636A/en
not_active
Application Discontinuation
1997-03-03
DE
DE59707503T
patent/DE59707503D1/en
not_active
Expired – Lifetime
1997-03-03
EE
EE9800302A
patent/EE03767B1/en
not_active
IP Right Cessation
1997-03-03
PT
PT97906150T
patent/PT885204E/en
unknown
1997-03-03
IL
IL12571097A
patent/IL125710A/en
not_active
IP Right Cessation
1997-03-03
CN
CN97192786A
patent/CN1072664C/en
not_active
Expired – Fee Related
1997-03-03
SK
SK1207-98A
patent/SK283052B6/en
unknown
1997-03-03
CA
CA002247257A
patent/CA2247257C/en
not_active
Expired – Lifetime
1997-03-03
JP
JP53143897A
patent/JP3465795B2/en
not_active
Expired – Lifetime
1997-03-03
EP
EP97906150A
patent/EP0885204B1/en
not_active
Expired – Lifetime
1997-03-03
DK
DK97906150T
patent/DK0885204T3/en
active
1997-03-03
ES
ES97906150T
patent/ES2177940T3/en
not_active
Expired – Lifetime
1997-03-03
YU
YU8197A
patent/YU8197A/en
unknown
1997-03-03
PL
PL97328779A
patent/PL328779A1/en
unknown
1997-03-03
CZ
CZ982814A
patent/CZ281498A3/en
unknown
1997-03-03
NZ
NZ332201A
patent/NZ332201A/en
unknown
1997-03-03
AU
AU20943/97A
patent/AU718584B2/en
not_active
Ceased
1997-03-03
BR
BR9708014A
patent/BR9708014A/en
not_active
IP Right Cessation
1997-03-04
ZA
ZA9701850A
patent/ZA971850B/en
unknown
1997-03-05
AR
ARP970100876A
patent/AR009938A1/en
not_active
Application Discontinuation
1997-03-05
ID
IDP970678A
patent/ID16128A/en
unknown
1997-03-05
HR
HR19608665.5A
patent/HRP970130A2/en
not_active
Application Discontinuation
1997-03-06
TW
TW086102712A
patent/TW375614B/en
active
1998
1998-08-21
BG
BG102715A
patent/BG102715A/en
active
Pending
1998-09-04
NO
NO19984080A
patent/NO311518B1/en
not_active
IP Right Cessation
1999
1999-06-22
HK
HK99102660A
patent/HK1019327A1/en
not_active
IP Right Cessation
2000
2000-11-01
US
US09/703,758
patent/US6498162B1/en
not_active
Expired – Lifetime
2002
2002-09-05
US
US10/235,053
patent/US7084140B2/en
not_active
Expired – Fee Related
Also Published As
Publication number
Publication date
BG102715A
(en)
1999-08-31
AU718584B2
(en)
2000-04-13
IL125710A
(en)
2002-09-12
US6498162B1
(en)
2002-12-24
CN1212689A
(en)
1999-03-31
ATE219069T1
(en)
2002-06-15
JP3465795B2
(en)
2003-11-10
ES2177940T3
(en)
2002-12-16
US7084140B2
(en)
2006-08-01
UA50762C2
(en)
2002-11-15
TW375614B
(en)
1999-12-01
CA2247257C
(en)
2006-11-21
EA002201B1
(en)
2002-02-28
EP0885204A1
(en)
1998-12-23
SK120798A3
(en)
1999-02-11
EA199800794A1
(en)
1999-04-29
DE59707503D1
(en)
2002-07-18
PL328779A1
(en)
1999-02-15
ID16128A
(en)
1997-09-04
HK1019327A1
(en)
2000-02-03
US20030092704A1
(en)
2003-05-15
NZ332201A
(en)
2000-01-28
YU8197A
(en)
2001-03-07
SK283052B6
(en)
2003-02-04
KR19990087636A
(en)
1999-12-27
NO984080L
(en)
1998-09-04
DK0885204T3
(en)
2002-09-23
CA2247257A1
(en)
1997-09-12
DE19608665A1
(en)
1997-09-11
CN1072664C
(en)
2001-10-10
WO1997032865A1
(en)
1997-09-12
TR199801734T2
(en)
1998-12-21
IL125710A0
(en)
1999-04-11
BR9708014A
(en)
1999-07-27
HU9901823A3
(en)
2000-01-28
EE03767B1
(en)
2002-06-17
HRP970130A2
(en)
1998-04-30
AR009938A1
(en)
2000-05-17
PT885204E
(en)
2002-10-31
JP2000506150A
(en)
2000-05-23
HU9901823A2
(en)
1999-09-28
NO311518B1
(en)
2001-12-03
EP0885204B1
(en)
2002-06-12
NO984080D0
(en)
1998-09-04
CZ281498A3
(en)
1999-01-13
ZA971850B
(en)
1997-09-08
EE9800302A
(en)
1999-02-15
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Legal Events
Date
Code
Title
Description
2000-08-10
FGA
Letters patent sealed or granted (standard patent)
2003-10-02
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
