AU2278588A

AU2278588A – Saccharide derivatives
– Google Patents

AU2278588A – Saccharide derivatives
– Google Patents
Saccharide derivatives

Info

Publication number
AU2278588A

AU2278588A
AU22785/88A
AU2278588A
AU2278588A
AU 2278588 A
AU2278588 A
AU 2278588A
AU 22785/88 A
AU22785/88 A
AU 22785/88A
AU 2278588 A
AU2278588 A
AU 2278588A
AU 2278588 A
AU2278588 A
AU 2278588A
Authority
AU
Australia
Prior art keywords
saccharide derivatives
immunostimulant
antiinflammatory
saccharides
deprotection
Prior art date
1987-09-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU22785/88A
Other versions

AU614772B2
(en

Inventor
Ingolf Macher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1987-09-23
Filing date
1988-09-23
Publication date
1989-04-20

1988-09-23
Application filed by Sandoz AG
filed
Critical
Sandoz AG

1989-04-20
Publication of AU2278588A
publication
Critical
patent/AU2278588A/en

1991-09-12
Application granted
granted
Critical

1991-09-12
Publication of AU614772B2
publication
Critical
patent/AU614772B2/en

1997-10-16
Assigned to NOVARTIS AG
reassignment
NOVARTIS AG
Request to Amend Deed and Register
Assignors: SANDOZ LTD.

2008-09-23
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS

C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium

C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen

C07H5/06—Aminosugars

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS

C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids

C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids

C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

C07H13/06—Fatty acids

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/12—Antivirals

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P35/00—Antineoplastic agents

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A61P37/02—Immunomodulators

A61P37/04—Immunostimulants

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P39/00—General protective or antinoxious agents

A61P39/02—Antidotes

Abstract

The saccharides of formula I, wherein R1, R2, R3 independently are optionally substituted acyl, are novel. They possess interesting pharmacological, especially immunostimulant, antiinflammatory and antitumor properties. They may be obtained by deprotection of a corresponding compound in protected form.

AU22785/88A
1987-09-23
1988-09-23
Saccharide derivatives

Expired

AU614772B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

DE3731953

1987-09-23

DE19873731953

DE3731953A1
(en)

1987-09-23
1987-09-23

NEW SACCHARID, METHOD FOR THEIR PRODUCTION AND THEIR USE

Publications (2)

Publication Number
Publication Date

AU2278588A
true

AU2278588A
(en)

1989-04-20

AU614772B2

AU614772B2
(en)

1991-09-12

Family
ID=6336635
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU22785/88A
Expired

AU614772B2
(en)

1987-09-23
1988-09-23
Saccharide derivatives

Country Status (18)

Country
Link

EP
(1)

EP0309411B1
(en)

JP
(1)

JP2744912B2
(en)

KR
(1)

KR970005346B1
(en)

AT
(1)

ATE102213T1
(en)

AU
(1)

AU614772B2
(en)

CA
(1)

CA1335892C
(en)

DE
(2)

DE3731953A1
(en)

DK
(1)

DK170170B1
(en)

ES
(1)

ES2061724T3
(en)

FI
(1)

FI89494C
(en)

HU
(1)

HU201559B
(en)

IE
(1)

IE63517B1
(en)

IL
(1)

IL87799A0
(en)

MY
(1)

MY103552A
(en)

NZ
(1)

NZ226274A
(en)

PL
(1)

PL157779B1
(en)

PT
(1)

PT88568B
(en)

ZA
(1)

ZA887161B
(en)

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

WO1990001938A1
(en)

*

1988-08-19
1990-03-08
The Australian National University
Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs

AU627500B2
(en)

*

1988-08-19
1992-08-27
Australian National University, The
Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs

Families Citing this family (7)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US5597573A
(en)

*

1989-05-04
1997-01-28
Igen, Inc.
Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities

PT94481B
(en)

*

1989-12-11
1997-02-28
Sankyo Co

PROCESS FOR THE PREPARATION OF LIPID ANALOGUES WITH IMMUNOACTIVITY AND ANTI-TUMOR ACTIVITY

US5593969A
(en)

*

1991-09-03
1997-01-14
Igen Incorporated
Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors

CA2366513A1
(en)

2000-02-10
2001-08-16
Mitsui Chemicals, Inc.
Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing a nucleoside

CA2317305A1
(en)

*

2000-08-29
2002-02-28
Tassos P. Anastassiades
Method of enhancing chondrocyte cell growth and glycosaminoglycan production

FR2862062B1
(en)

*

2003-11-06
2005-12-23
Oreal

LIPID A AND TOPICAL COMPOSITION, IN PARTICULAR COSMETIC, COMPRISING IT

EP3707147A1
(en)

*

2017-11-07
2020-09-16
Università Degli Studi Di Milano – Bicocca
New synthetic agonists of tlr4 receptor

Family Cites Families (5)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS60501259A
(en)

*

1983-05-06
1985-08-08
ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン

Monosaccharide compounds with immunostimulatory activity

EP0180608B1
(en)

1984-04-21
1990-07-25
Sandoz Ag
2,3-diamino-2,3-didesoxyhexose derivatives, processes for their preparation and their use

EP0219514A4
(en)

*

1985-04-03
1988-04-26
Wisconsin Alumni Res Found
Method of preventing diseases caused by gram-negative endotoxin in mammals.

NL8601551A
(en)

1985-06-28
1987-01-16
Sandoz Ag

NEW SACCHARIDES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

US4746742A
(en)

*

1985-11-28
1988-05-24
Toho Yakuhin Kogyo Kabushiki Kaisha
Analogs of nonreducing monosaccharide moiety of lipid A

1987

1987-09-23
DE
DE19873731953
patent/DE3731953A1/en
not_active
Withdrawn

1988

1988-09-19
IL
IL87799A
patent/IL87799A0/en
active
Protection Beyond IP Right Term

1988-09-20
HU
HU884921A
patent/HU201559B/en
unknown

1988-09-21
AT
AT88810646T
patent/ATE102213T1/en
not_active
IP Right Cessation

1988-09-21
ES
ES88810646T
patent/ES2061724T3/en
not_active
Expired – Lifetime

1988-09-21
NZ
NZ226274A
patent/NZ226274A/en
unknown

1988-09-21
IE
IE285988A
patent/IE63517B1/en
not_active
IP Right Cessation

1988-09-21
DE
DE3888066T
patent/DE3888066T2/en
not_active
Expired – Lifetime

1988-09-21
FI
FI884345A
patent/FI89494C/en
not_active
IP Right Cessation

1988-09-21
DK
DK525588A
patent/DK170170B1/en
active
IP Right Grant

1988-09-21
PT
PT88568A
patent/PT88568B/en
not_active
IP Right Cessation

1988-09-21
EP
EP88810646A
patent/EP0309411B1/en
not_active
Expired – Lifetime

1988-09-21
MY
MYPI88001053A
patent/MY103552A/en
unknown

1988-09-22
JP
JP63239548A
patent/JP2744912B2/en
not_active
Expired – Lifetime

1988-09-22
KR
KR1019880012262A
patent/KR970005346B1/en
not_active
IP Right Cessation

1988-09-22
CA
CA000578482A
patent/CA1335892C/en
not_active
Expired – Lifetime

1988-09-23
AU
AU22785/88A
patent/AU614772B2/en
not_active
Expired

1988-09-23
PL
PL1988274862A
patent/PL157779B1/en
unknown

1988-09-23
ZA
ZA887161A
patent/ZA887161B/en
unknown

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

WO1990001938A1
(en)

*

1988-08-19
1990-03-08
The Australian National University
Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs

AU627500B2
(en)

*

1988-08-19
1992-08-27
Australian National University, The
Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs

Also Published As

Publication number
Publication date

PL274862A1
(en)

1989-06-12

JP2744912B2
(en)

1998-04-28

KR970005346B1
(en)

1997-04-15

EP0309411A2
(en)

1989-03-29

EP0309411A3
(en)

1991-07-24

MY103552A
(en)

1993-07-31

JPH01121295A
(en)

1989-05-12

ZA887161B
(en)

1990-05-30

CA1335892C
(en)

1995-06-13

DK525588D0
(en)

1988-09-21

DE3888066T2
(en)

1994-08-04

EP0309411B1
(en)

1994-03-02

DE3731953A1
(en)

1989-04-06

IE882859L
(en)

1989-03-23

NZ226274A
(en)

1991-03-26

DK170170B1
(en)

1995-06-06

DE3888066D1
(en)

1994-04-07

AU614772B2
(en)

1991-09-12

HUT50193A
(en)

1989-12-28

PL157779B1
(en)

1992-07-31

FI884345A
(en)

1989-03-24

IL87799A0
(en)

1989-03-31

HU201559B
(en)

1990-11-28

PT88568B
(en)

1992-11-30

FI89494B
(en)

1993-06-30

DK525588A
(en)

1989-03-24

KR890005138A
(en)

1989-05-13

ES2061724T3
(en)

1994-12-16

FI884345A0
(en)

1988-09-21

IE63517B1
(en)

1995-05-03

FI89494C
(en)

1993-10-11

PT88568A
(en)

1988-10-01

ATE102213T1
(en)

1994-03-15

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