AU2972092A

AU2972092A – Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained
– Google Patents

AU2972092A – Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained
– Google Patents
Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained

Info

Publication number
AU2972092A

AU2972092A
AU29720/92A
AU2972092A
AU2972092A
AU 2972092 A
AU2972092 A
AU 2972092A
AU 29720/92 A
AU29720/92 A
AU 29720/92A
AU 2972092 A
AU2972092 A
AU 2972092A
AU 2972092 A
AU2972092 A
AU 2972092A
Authority
AU
Australia
Prior art keywords
obtaining
pure preparations
products obtained
melarsomine dihydrochloride
intermediate products
Prior art date
1991-12-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU29720/92A
Other versions

AU667329B2
(en

Inventor
Jean-Pierre Etchegaray
Robert Floch
Patrick Lubert
Regine Jackie Anne-Marie Mazars
Gerard Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Animal Health USA Inc

Original Assignee
Merial SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1991-12-02
Filing date
1992-11-27
Publication date
1993-06-03

1992-11-27
Application filed by Merial SAS
filed
Critical
Merial SAS

1993-06-03
Publication of AU2972092A
publication
Critical
patent/AU2972092A/en

1996-03-21
Application granted
granted
Critical

1996-03-21
Publication of AU667329B2
publication
Critical
patent/AU667329B2/en

1996-06-21
Priority to AU56149/96A
priority
Critical
patent/AU700833B2/en

1998-05-14
Assigned to MERIAL
reassignment
MERIAL
Request to Amend Deed and Register
Assignors: RHONE MERIEUX

2012-11-27
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

WMZUMAJTJUZEKQ-UHFFFAOYSA-N
2-n-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine;dihydrochloride
Chemical compound

Cl.Cl.C1=CC([As](SCCN)SCCN)=CC=C1NC1=NC(N)=NC(N)=N1
WMZUMAJTJUZEKQ-UHFFFAOYSA-N
0.000
title
1

239000013067
intermediate product
Substances

0.000
title
1

229940126601
medicinal product
Drugs

0.000
title
1

229960004330
melarsomine dihydrochloride
Drugs

0.000
title
1

238000000034
method
Methods

0.000
title
1

238000002360
preparation method
Methods

0.000
title
1

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM

C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System

C07F9/66—Arsenic compounds

C07F9/70—Organo-arsenic compounds

C07F9/80—Heterocyclic compounds

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P33/00—Antiparasitic agents

A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM

C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System

C07F9/66—Arsenic compounds

C07F9/70—Organo-arsenic compounds

C07F9/74—Aromatic compounds

AU29720/92A
1991-12-02
1992-11-27
Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained

Expired

AU667329B2
(en)

Priority Applications (1)

Application Number
Priority Date
Filing Date
Title

AU56149/96A

AU700833B2
(en)

1991-12-02
1996-06-21
Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

FR919114904A

FR2684382B1
(en)

1991-12-02
1991-12-02

DRUGS AND PURE PREPARATIONS OF MELARSOMINE DICHLORHYDRATE, PROCESS FOR OBTAINING SAME AND INTERMEDIATE PRODUCTS OBTAINED.

FR9114904

1991-12-02

Related Child Applications (1)

Application Number
Title
Priority Date
Filing Date

AU56149/96A
Division

AU700833B2
(en)

1991-12-02
1996-06-21
Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained

Publications (2)

Publication Number
Publication Date

AU2972092A
true

AU2972092A
(en)

1993-06-03

AU667329B2

AU667329B2
(en)

1996-03-21

Family
ID=9419573
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU29720/92A
Expired

AU667329B2
(en)

1991-12-02
1992-11-27
Medicinal products and pure preparations of melarsomine dihydrochloride, process for obtaining them and intermediate products obtained

Country Status (15)

Country
Link

US
(3)

US5459263A
(en)

JP
(1)

JP3578277B2
(en)

AU
(1)

AU667329B2
(en)

BR
(1)

BR9204643A
(en)

CA
(1)

CA2083766C
(en)

ES
(1)

ES2039311B1
(en)

FR
(1)

FR2684382B1
(en)

GR
(1)

GR920100526A
(en)

IT
(1)

IT1256117B
(en)

MA
(1)

MA22723A1
(en)

MX
(1)

MX9206890A
(en)

MY
(1)

MY111175A
(en)

PH
(1)

PH31115A
(en)

PT
(1)

PT101105B
(en)

TW
(1)

TW358099B
(en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2684382B1
(en)

*

1991-12-02
1994-10-21
Rhone Merieux

DRUGS AND PURE PREPARATIONS OF MELARSOMINE DICHLORHYDRATE, PROCESS FOR OBTAINING SAME AND INTERMEDIATE PRODUCTS OBTAINED.

US6191123B1
(en)

*

1999-03-19
2001-02-20
Parker Hughes Institute
Organic-arsenic compounds

AUPQ296799A0
(en)

*

1999-09-20
1999-10-14
Unisearch Limited
A cell-membrane impermeable trivalent organoarsenical derivative and use thereof

CN101863958B
(en)

2002-11-07
2012-07-18
新南创新私人有限公司
Induction of the mitochondrial permeability transition

US6686344B1
(en)

2003-01-30
2004-02-03
Paker Hughes Institute
Organic-arsonic compounds

WO2008052279A1
(en)

2006-11-01
2008-05-08
Newsouth Innovations Pty Limited
Organo-arsenoxide compounds and use thereof

US8324895B2
(en)

*

2009-01-23
2012-12-04
Baker Hughes Incorporated
MWD/LWD NMR imaging with long echo trains

US8373412B2
(en)

*

2009-01-23
2013-02-12
Baker Hughes Incorporated
NMR-LWD imaging tool

CN102558234B
(en)

*

2011-04-08
2015-01-07
浙江工商大学
Method for preparing arsanilic acid preparation by diazotization of amino phenylarsonic acid

CN102558235B
(en)

*

2011-04-08
2015-01-07
浙江工商大学
Method for preparing arsanilic acid by diazotizing trimethoprim

US20140051840A1
(en)

*

2012-08-17
2014-02-20
The Curators Of The University Of Missouri
Arsenic complexes for potential diagnostic applications

US9593052B2
(en)

2012-08-17
2017-03-14
The Curators Of The University Of Missouri
Arsenic complexes for potential diagnostic applications

Family Cites Families (19)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

BE437342A
(en)

*

1938-12-23
1900-01-01

NL60802C
(en)

*

1940-12-10

CH242529A
(en)

*

1940-12-10
1946-05-15
Friedheim Ernst Albert Hermann

Process for the preparation of m- (2,4-diamino-1,3,5-triazinyl- (6)) -amino-phenylarsine oxide.

US2400547A
(en)

*

1944-01-20
1946-05-21
Ernst A H Friedheim
Substituted 1, 3, 5-triazinyl-(6)-aminophenyl-arsenic compounds

US2422724A
(en)

*

1944-01-20
1947-06-24
Ernst A H Friedheim
Substituted 1,3,5-triazinyl-(6)-aminophenyl-arsenic compounds

US2390091A
(en)

*

1944-06-03
1945-11-27
Ernst A H Friedheim
Substituted 1,3,5-triazinyl-(6)-aminophenyl-arsenic compounds

CH254164A
(en)

*

1946-11-16
1948-04-15
Dr Friedheim Ernst A H

Process for the preparation of p- (2,4-diamino-1,3,5-triazinyl- (6) -aminophenyl-arsenic oxide.

CH245837A
(en)

*

1946-11-16
1946-11-30
Dr Friedheim Ernst A H

Process for the preparation of p-2,4-diamino-1,3,5-triazinyl- (6) -amino-phenyl-arsenic oxide.

US2659723A
(en)

*

1947-01-28
1953-11-17
Ernst A H Friedheim
Triazine organometallic compounds and process for preparing same

US2593434A
(en)

*

1947-02-19
1952-04-22
Ernst A H Friedheim
Propylene glycol solution of arsenic medicaments

US3482171A
(en)

*

1966-07-15
1969-12-02
Itt
Bidirectional electronic phase shifter

BE786573A
(en)

*

1971-07-20
1973-01-22
Hoechst Ag

MEDICINAL PRODUCT BASED ON ORGANIC ARSENICAL COMPOUNDS AND BENZIMIDAZOLE DERIVATIVES

US3856971A
(en)

*

1971-07-20
1974-12-24
E Friedheim
Method of combating filariasis in dogs

GB2024008B
(en)

*

1978-06-28
1983-02-16
Merck & Co Inc
Compositions for treating trypanosomiasis infections

ZW8781A1
(en)

*

1980-05-23
1981-12-16
Hoffmann La Roche
2-nitroimidazoles and preparation thereof

US4514390A
(en)

*

1982-04-12
1985-04-30
The Rockefeller University
Melaminylthioarsenites

FR2572730B1
(en)

*

1984-11-02
1987-12-11
Centre Nat Rech Scient

NOVEL ARSENIC DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION, IN PARTICULAR AS PEST CONTROL MEDICINES

FR2640269B1
(en)

*

1988-12-13
1991-03-15
Maes Ludo

ORGANOMETALLIC COMPOUNDS, METHODS OF PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

FR2684382B1
(en)

*

1991-12-02
1994-10-21
Rhone Merieux

DRUGS AND PURE PREPARATIONS OF MELARSOMINE DICHLORHYDRATE, PROCESS FOR OBTAINING SAME AND INTERMEDIATE PRODUCTS OBTAINED.

1991

1991-12-02
FR
FR919114904A
patent/FR2684382B1/en
not_active
Expired – Lifetime

1992

1992-11-25
IT
ITMI922692A
patent/IT1256117B/en
active
IP Right Grant

1992-11-25
CA
CA002083766A
patent/CA2083766C/en
not_active
Expired – Lifetime

1992-11-25
PH
PH45320A
patent/PH31115A/en
unknown

1992-11-25
ES
ES09202376A
patent/ES2039311B1/en
not_active
Expired – Fee Related

1992-11-26
GR
GR920100526A
patent/GR920100526A/en
unknown

1992-11-27
AU
AU29720/92A
patent/AU667329B2/en
not_active
Expired

1992-11-27
MY
MYPI92002180A
patent/MY111175A/en
unknown

1992-11-30
MX
MX9206890A
patent/MX9206890A/en
unknown

1992-11-30
PT
PT101105A
patent/PT101105B/en
not_active
IP Right Cessation

1992-12-01
MA
MA23013A
patent/MA22723A1/en
unknown

1992-12-01
BR
BR9204643A
patent/BR9204643A/en
not_active
Application Discontinuation

1992-12-02
JP
JP34986692A
patent/JP3578277B2/en
not_active
Expired – Lifetime

1992-12-02
US
US07/984,934
patent/US5459263A/en
not_active
Expired – Lifetime

1992-12-11
TW
TW081109949A
patent/TW358099B/en
not_active
IP Right Cessation

1995

1995-06-02
US
US08/459,797
patent/US5635499A/en
not_active
Expired – Lifetime

1996

1996-09-05
US
US08/707,613
patent/US5770733A/en
not_active
Expired – Fee Related

Also Published As

Publication number
Publication date

US5635499A
(en)

1997-06-03

MY111175A
(en)

1999-09-30

MA22723A1
(en)

1993-07-01

IT1256117B
(en)

1995-11-28

ITMI922692D0
(en)

1992-11-25

MX9206890A
(en)

1993-08-01

GR920100526A
(en)

1993-08-31

ES2039311A1
(en)

1993-09-16

PT101105A
(en)

1994-03-31

ES2039311B1
(en)

1997-08-16

JPH0624960A
(en)

1994-02-01

CA2083766A1
(en)

1993-06-03

BR9204643A
(en)

1993-06-08

ITMI922692A1
(en)

1994-05-25

US5770733A
(en)

1998-06-23

TW358099B
(en)

1999-05-11

FR2684382B1
(en)

1994-10-21

FR2684382A1
(en)

1993-06-04

US5459263A
(en)

1995-10-17

CA2083766C
(en)

2002-09-10

PT101105B
(en)

1999-10-29

JP3578277B2
(en)

2004-10-20

PH31115A
(en)

1998-02-23

AU667329B2
(en)

1996-03-21

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