AU3017197A – Insulin derivatives with increased zinc binding
– Google Patents
AU3017197A – Insulin derivatives with increased zinc binding
– Google Patents
Insulin derivatives with increased zinc binding
Info
Publication number
AU3017197A
AU3017197A
AU30171/97A
AU3017197A
AU3017197A
AU 3017197 A
AU3017197 A
AU 3017197A
AU 30171/97 A
AU30171/97 A
AU 30171/97A
AU 3017197 A
AU3017197 A
AU 3017197A
AU 3017197 A
AU3017197 A
AU 3017197A
Authority
AU
Australia
Prior art keywords
insulin derivatives
zinc binding
increased zinc
increased
binding
Prior art date
1996-07-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU30171/97A
Other versions
AU725201B2
(en
Inventor
Johann Ertl
Karl Geisen
Paul Habermann
Gerhard Seipke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1996-07-26
Filing date
1997-07-24
Publication date
1998-02-05
1997-07-24
Application filed by Hoechst AG
filed
Critical
Hoechst AG
1998-02-05
Publication of AU3017197A
publication
Critical
patent/AU3017197A/en
2000-10-05
Application granted
granted
Critical
2000-10-05
Publication of AU725201B2
publication
Critical
patent/AU725201B2/en
2017-07-24
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
C07K14/575—Hormones
C07K14/62—Insulins
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P5/00—Drugs for disorders of the endocrine system
A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P5/00—Drugs for disorders of the endocrine system
A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K38/00—Medicinal preparations containing peptides
AU30171/97A
1996-07-26
1997-07-24
Insulin derivatives with increased zinc binding
Ceased
AU725201B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19630242
1996-07-26
DE19630242
1996-07-26
Publications (2)
Publication Number
Publication Date
AU3017197A
true
AU3017197A
(en)
1998-02-05
AU725201B2
AU725201B2
(en)
2000-10-05
Family
ID=7800962
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU30171/97A
Ceased
AU725201B2
(en)
1996-07-26
1997-07-24
Insulin derivatives with increased zinc binding
Country Status (25)
Country
Link
US
(1)
US6221837B1
(en)
EP
(1)
EP0821006B1
(en)
JP
(1)
JP4046388B2
(en)
KR
(1)
KR100547922B1
(en)
CN
(2)
CN1158305C
(en)
AR
(1)
AR008269A1
(en)
AT
(1)
ATE264871T1
(en)
AU
(1)
AU725201B2
(en)
BR
(1)
BR9704117B1
(en)
CA
(1)
CA2207078C
(en)
CZ
(1)
CZ292274B6
(en)
DE
(1)
DE59711533D1
(en)
DK
(1)
DK0821006T3
(en)
ES
(1)
ES2218622T3
(en)
HK
(1)
HK1048125A1
(en)
HU
(1)
HU224591B1
(en)
IL
(2)
IL121382A0
(en)
NO
(1)
NO317666B1
(en)
NZ
(1)
NZ328421A
(en)
PL
(1)
PL188617B1
(en)
PT
(1)
PT821006E
(en)
RU
(1)
RU2176646C2
(en)
TR
(1)
TR199700685A2
(en)
TW
(1)
TW474944B
(en)
ZA
(1)
ZA976645B
(en)
Families Citing this family (27)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE19825447A1
(en)
*
1998-06-06
1999-12-09
Hoechst Marion Roussel De Gmbh
New insulin analogues with increased zinc formation
DE19838097A1
(en)
1998-08-24
2000-03-02
Hoechst Marion Roussel De Gmbh
Process for the chromatographic purification of insulins
DE19947456A1
(en)
*
1999-10-02
2001-04-05
Aventis Pharma Gmbh
New synthetic derivatives of the C-peptide of proinsulin, useful in the preparation of human insulin or insulin analogs in high yield
EP1432430A4
(en)
*
2001-08-28
2006-05-10
Lilly Co Eli
Pre-mixes of glp-1 and basal insulin
WO2003035099A1
(en)
*
2001-10-19
2003-05-01
Eli Lilly And Company
Biphasic mixtures of glp-1 and insulin
KR100769183B1
(en)
*
2001-12-28
2007-10-23
엘지.필립스 엘시디 주식회사
Flat Luminescene Lamp
AU2004234345A1
(en)
*
2003-04-29
2004-11-11
Eli Lilly And Company
Insulin analogs having protracted time action
MXPA06001283A
(en)
*
2003-08-05
2006-04-11
Novo Nordisk As
Novel insulin derivatives.
CN105801686B
(en)
2004-07-19
2020-04-07
比奥孔有限公司
Insulin-oligomer conjugates, formulations and uses thereof
US7833513B2
(en)
2004-12-03
2010-11-16
Rhode Island Hospital
Treatment of Alzheimer’s Disease
ATE519780T1
(en)
2005-12-28
2011-08-15
Novo Nordisk As
COMPOSITIONS CONTAINING ACYLATED INSULIN AND ZINC AND METHOD FOR PRODUCING THESE COMPOSITIONS
WO2008015099A2
(en)
*
2006-07-31
2008-02-07
Novo Nordisk A/S
Pegylated, extended insulins
BRPI0717098B8
(en)
*
2006-09-22
2021-05-25
Novo Nordisk As
protease-resistant human insulin analogues, pharmaceutical composition and process for their preparation
US9387176B2
(en)
*
2007-04-30
2016-07-12
Novo Nordisk A/S
Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
US20100190706A1
(en)
*
2007-06-01
2010-07-29
Novo Nordisk A/S
Stable Non-Aqueous Pharmaceutical Compositions
WO2008152106A1
(en)
*
2007-06-13
2008-12-18
Novo Nordisk A/S
Pharmaceutical formulation comprising an insulin derivative
JP5868594B2
(en)
*
2007-10-16
2016-02-24
バイオコン・リミテッドＢｉｏｃｏｎ Ｌｉｍｉｔｅｄ
Orally administrable solid pharmaceutical composition and process thereof
US9260502B2
(en)
*
2008-03-14
2016-02-16
Novo Nordisk A/S
Protease-stabilized insulin analogues
MX2010009850A
(en)
2008-03-18
2010-09-30
Novo Nordisk As
Protease stabilized, acylated insulin analogues.
CA2738615A1
(en)
*
2008-10-30
2010-05-06
Novo Nordisk A/S
Treating diabetes melitus using insulin injections with less than daily injection frequency
DK2632478T3
(en)
2010-10-27
2019-10-07
Novo Nordisk As
TREATMENT OF DIABETES MELITUS USING INSULIN INJECTIONS SUBMITTED AT VARIOUS INJECTION INTERVALS
US9481721B2
(en)
2012-04-11
2016-11-01
Novo Nordisk A/S
Insulin formulations
JP2016519127A
(en)
2013-04-30
2016-06-30
ノヴォ ノルディスク アー／エス
New dosing regimen
CA2926701A1
(en)
2013-10-07
2015-04-16
Novo Nordisk A/S
Novel derivative of an insulin analogue
FR3013049B1
(en)
2013-11-14
2015-11-13
You-Ping Chan
ANALOGUE OF INSULIN GLARGINE
EP3821905B1
(en)
2016-12-16
2022-10-12
Novo Nordisk A/S
Insulin containing pharmaceutical compositions
US10335464B1
(en)
2018-06-26
2019-07-02
Novo Nordisk A/S
Device for titrating basal insulin
Family Cites Families (26)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FI78616C
(en)
*
1982-02-05
1989-09-11
Novo Industri As
Process for preparing an infused stabilized insulin solution having an elevated zinc content
DE3326472A1
(en)
1983-07-22
1985-02-14
Hoechst Ag, 6230 Frankfurt
NEW INSULIN DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AND PHARMACEUTICAL AGENTS FOR TREATING THE DIABETES MELLITUS
DE3327709A1
(en)
*
1983-07-29
1985-02-07
Hoechst Ag, 6230 Frankfurt
INSULIN DERIVATIVE CRYSTAL SUSPENSIONS, METHOD FOR THE PRODUCTION AND USE THEREOF
DE3440988A1
(en)
1984-11-09
1986-07-10
Hoechst Ag, 6230 Frankfurt
METHOD FOR CLEAVING PEPTIDES AND PROTEINS ON THE METHIONYL BOND
US4569794A
(en)
1984-12-05
1986-02-11
Eli Lilly And Company
Process for purifying proteins and compounds useful in such process
US5008241A
(en)
*
1985-03-12
1991-04-16
Novo Nordisk A/S
Novel insulin peptides
DE3526995A1
(en)
1985-07-27
1987-02-05
Hoechst Ag
FUSION PROTEINS, METHOD FOR THEIR PRODUCTION AND THEIR USE
DE3636903A1
(en)
1985-12-21
1987-07-02
Hoechst Ag
FUSION PROTEINS WITH EUKARYOTIC BALLASTES
DE3541856A1
(en)
1985-11-27
1987-06-04
Hoechst Ag
EUKARYOTIC FUSION PROTEINS, THEIR PRODUCTION AND USE, AND MEANS FOR CARRYING OUT THE PROCESS
CA1340522C
(en)
1987-03-10
1999-05-04
Heinz Dobeli
Fusion proteins containing neighbouring histidines for improved purification
DE3805150A1
(en)
1987-04-11
1988-10-20
Hoechst Ag
GENE TECHNOLOGICAL METHOD FOR PRODUCING POLYPEPTIDES
DE4012818A1
(en)
1990-04-21
1991-10-24
Hoechst Ag
METHOD FOR THE PRODUCTION OF FOREIGN PROTEINS IN STREPTOMYCETES
DE3726655A1
(en)
1987-08-11
1989-02-23
Hoechst Ag
METHOD FOR ISOLATING BASIC PROTEINS FROM PROTEIN MIXTURES CONTAINING SUCH BASIC PROTEINS
DE3739347A1
(en)
1987-11-20
1989-06-01
Hoechst Ag
METHOD FOR SELECTIVE CLEAVAGE OF FUSION PROTEINS
EP0347781B1
(en)
1988-06-23
1994-02-16
Hoechst Aktiengesellschaft
Mini-proinsulin, its oroduction and use
DE3827533A1
(en)
*
1988-08-13
1990-02-15
Hoechst Ag
PHARMACEUTICAL PREPARATION FOR TREATING THE DIABETES MELLITUS
DE3837825A1
(en)
1988-11-08
1990-05-10
Hoechst Ag
NEW INSULIN DERIVATIVES, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THEM
NZ232375A
(en)
*
1989-02-09
1992-04-28
Lilly Co Eli
Insulin analogues modified at b29
DE3921447A1
(en)
*
1989-06-30
1991-01-17
Hoechst Ag
METHOD FOR PRODUCING N-ALKYL HALOGENANILINE
IL95495A
(en)
1989-08-29
1996-10-16
Hoechst Ag
Fusion proteins their preparation and use
US5358857A
(en)
1989-08-29
1994-10-25
The General Hospital Corp.
Method of preparing fusion proteins
US5227293A
(en)
1989-08-29
1993-07-13
The General Hospital Corporation
Fusion proteins, their preparation and use
CZ342492A3
(en)
*
1991-11-26
1993-06-16
Lilly Co Eli
Derivatives of tri-arginine insulin, process of their preparation and a pharmaceutical composition in which said derivatives are comprised
SG46612A1
(en)
1992-12-02
1998-02-20
Hoechst Ag
Process for obtaining proinsulin in processing correctly linked cystine bridges
DE4405179A1
(en)
1994-02-18
1995-08-24
Hoechst Ag
Method of obtaining insulin with correctly connected cystine bridges
ATE306930T1
(en)
*
1994-08-12
2005-11-15
Immunomedics Inc
IMMUNE CONJUGATES AND HUMAN ANTIBODIES SPECIFIC FOR B-CELL LYMPHOMA AND LEUKEMIA CELLS
1997
1997-07-17
AT
AT97112197T
patent/ATE264871T1/en
active
1997-07-17
EP
EP97112197A
patent/EP0821006B1/en
not_active
Expired – Lifetime
1997-07-17
DE
DE59711533T
patent/DE59711533D1/en
not_active
Expired – Lifetime
1997-07-17
PT
PT97112197T
patent/PT821006E/en
unknown
1997-07-17
DK
DK97112197T
patent/DK0821006T3/en
active
1997-07-17
ES
ES97112197T
patent/ES2218622T3/en
not_active
Expired – Lifetime
1997-07-24
AU
AU30171/97A
patent/AU725201B2/en
not_active
Ceased
1997-07-24
NZ
NZ328421A
patent/NZ328421A/en
not_active
IP Right Cessation
1997-07-24
TW
TW086110516A
patent/TW474944B/en
not_active
IP Right Cessation
1997-07-24
TR
TR97/00685A
patent/TR199700685A2/en
unknown
1997-07-24
AR
ARP970103352A
patent/AR008269A1/en
active
IP Right Grant
1997-07-24
CZ
CZ19972370A
patent/CZ292274B6/en
not_active
IP Right Cessation
1997-07-24
IL
IL12138297A
patent/IL121382A0/en
unknown
1997-07-24
IL
IL12138197A
patent/IL121381A/en
not_active
IP Right Cessation
1997-07-24
RU
RU97112742/04A
patent/RU2176646C2/en
not_active
IP Right Cessation
1997-07-25
CA
CA002207078A
patent/CA2207078C/en
not_active
Expired – Fee Related
1997-07-25
NO
NO19973438A
patent/NO317666B1/en
not_active
IP Right Cessation
1997-07-25
HU
HU9701299A
patent/HU224591B1/en
not_active
IP Right Cessation
1997-07-25
KR
KR1019970034958A
patent/KR100547922B1/en
not_active
IP Right Cessation
1997-07-25
ZA
ZA9706645A
patent/ZA976645B/en
unknown
1997-07-25
JP
JP20000297A
patent/JP4046388B2/en
not_active
Expired – Fee Related
1997-07-25
US
US08/900,574
patent/US6221837B1/en
not_active
Expired – Lifetime
1997-07-25
PL
PL97321343A
patent/PL188617B1/en
not_active
IP Right Cessation
1997-07-25
CN
CNB971046751A
patent/CN1158305C/en
not_active
Expired – Fee Related
1997-07-28
BR
BRPI9704117-3A
patent/BR9704117B1/en
not_active
IP Right Cessation
2001
2001-12-17
CN
CN01143664A
patent/CN1362417A/en
active
Pending
2003
2003-01-07
HK
HK03100149.7A
patent/HK1048125A1/en
unknown
Also Published As
Publication number
Publication date
BR9704117A
(en)
1998-12-29
EP0821006B1
(en)
2004-04-21
HU9701299A3
(en)
2001-04-28
NO317666B1
(en)
2004-11-29
HU9701299D0
(en)
1997-09-29
NO973438D0
(en)
1997-07-25
ES2218622T3
(en)
2004-11-16
TW474944B
(en)
2002-02-01
BR9704117B1
(en)
2009-08-11
US6221837B1
(en)
2001-04-24
ZA976645B
(en)
1998-01-26
NZ328421A
(en)
1998-12-23
IL121381A0
(en)
1998-01-04
HU9701299A2
(en)
1998-11-30
ATE264871T1
(en)
2004-05-15
JPH1072496A
(en)
1998-03-17
CN1172811A
(en)
1998-02-11
HU224591B1
(en)
2005-11-28
PL321343A1
(en)
1998-02-02
CA2207078C
(en)
2008-01-29
IL121382A0
(en)
1998-01-04
NO973438L
(en)
1998-01-27
DK0821006T3
(en)
2004-08-16
DE59711533D1
(en)
2004-05-27
JP4046388B2
(en)
2008-02-13
TR199700685A3
(en)
1998-02-21
HK1048125A1
(en)
2003-03-21
RU2176646C2
(en)
2001-12-10
PT821006E
(en)
2004-09-30
CA2207078A1
(en)
1998-01-26
CZ292274B6
(en)
2003-08-13
CN1158305C
(en)
2004-07-21
AU725201B2
(en)
2000-10-05
TR199700685A2
(en)
1998-02-21
IL121381A
(en)
2004-09-27
AR008269A1
(en)
1999-12-29
CZ237097A3
(en)
1998-02-18
EP0821006A3
(en)
2001-11-28
KR980009281A
(en)
1998-04-30
MX9705667A
(en)
1998-07-31
KR100547922B1
(en)
2006-06-22
EP0821006A2
(en)
1998-01-28
PL188617B1
(en)
2005-03-31
CN1362417A
(en)
2002-08-07
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Legal Events
Date
Code
Title
Description
2001-02-08
FGA
Letters patent sealed or granted (standard patent)
