AU3914285A - Creation of Inventions and Patents with Artificial Intelligence

AU3914285A – Pyrido-benzothiazine derivatives
– Google Patents

AU3914285A – Pyrido-benzothiazine derivatives
– Google Patents
Pyrido-benzothiazine derivatives

Info

Publication number
AU3914285A

AU3914285A
AU39142/85A
AU3914285A
AU3914285A
AU 3914285 A
AU3914285 A
AU 3914285A
AU 39142/85 A
AU39142/85 A
AU 39142/85A
AU 3914285 A
AU3914285 A
AU 3914285A
AU 3914285 A
AU3914285 A
AU 3914285A
Authority
AU
Australia
Prior art keywords
pyrido
chem
general formula
processes
derivatives
Prior art date
1984-02-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU39142/85A
Other versions

AU573780B2
(en

Inventor
Arnaldo Fravolini
Giuseppe Mascellani
Patrizia Terni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mediolanum Farmaceutici SpA

Original Assignee
Mediolanum Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1984-02-24
Filing date
1985-02-25
Publication date
1985-09-05

1985-02-25
Application filed by Mediolanum Farmaceutici SpA
filed
Critical
Mediolanum Farmaceutici SpA

1985-09-05
Publication of AU3914285A
publication
Critical
patent/AU3914285A/en

1988-06-23
Application granted
granted
Critical

1988-06-23
Publication of AU573780B2
publication
Critical
patent/AU573780B2/en

1992-09-03
Assigned to MEDIOLANUM FARMACEUTICI S.P.A.
reassignment
MEDIOLANUM FARMACEUTICI S.P.A.
Request to Amend Deed and Register
Assignors: MEDIOLANUM FARMACEUTICI S.R.L.

2005-02-25
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 – C07D507/00

C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 – C07D507/00 in which the condensed system contains two hetero rings

C07D513/06—Peri-condensed systems

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems

C07D277/62—Benzothiazoles

C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

C07D277/82—Nitrogen atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms

C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines

C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems

C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Abstract

Pyridobenzothiazine derivatives with high antimicrobial activity having the following general formula:

wherein
R is H or CH3; n is 0 or 1 or 2 and Y is Cl or F,

wherein R<1> is a C1-C6 alkyl
or a C2-C6 alkenyl, or an arylalkyl, arylalkylcarbonyl, alkylcarbonyl, alkyloxycarbonyl, possibly substituted with halogens or hydroxy groups.
The present invention relates also to the processes for obtaining the compounds having the general formula (I). Such processes consist in synthesis routes using as starting products 3-chloro-4-fluoraniline, or 2,3,4-trifluoronitrobenzene.

AU39142/85A
1984-02-24
1985-02-25
Pyrido-benzothiazine derivatives

Ceased

AU573780B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

IT19790/84

1984-02-24

IT19790/84A

IT1173374B
(en)

1984-02-24
1984-02-24

PYRID-BENZOTHIAZINIC DERIVATIVES WITH HIGH ANTIMICROBIAL ACTIVITY

Publications (2)

Publication Number
Publication Date

AU3914285A
true

AU3914285A
(en)

1985-09-05

AU573780B2

AU573780B2
(en)

1988-06-23

Family
ID=11161233
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU39142/85A
Ceased

AU573780B2
(en)

1984-02-24
1985-02-25
Pyrido-benzothiazine derivatives

Country Status (22)

Country
Link

US
(2)

US4668784A
(en)

EP
(1)

EP0165375B1
(en)

JP
(2)

JPS60208987A
(en)

KR
(1)

KR880000024B1
(en)

AT
(1)

ATE57532T1
(en)

AU
(1)

AU573780B2
(en)

CA
(1)

CA1340554C
(en)

DE
(1)

DE3580124D1
(en)

DK
(1)

DK81885A
(en)

EG
(1)

EG17585A
(en)

ES
(3)

ES8801923A1
(en)

FI
(1)

FI83327C
(en)

GR
(1)

GR850482B
(en)

IE
(1)

IE57974B1
(en)

IT
(1)

IT1173374B
(en)

MX
(5)

MX172473B
(en)

NO
(1)

NO171163C
(en)

NZ
(1)

NZ211224A
(en)

PH
(2)

PH22239A
(en)

PT
(1)

PT80003B
(en)

YU
(1)

YU43401B
(en)

ZA
(1)

ZA851379B
(en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2358580A1
(en)

1976-07-16
1978-02-10
Comet

IMPROVEMENTS TO CAGES FOR PRISONER NUTS AND TO APPARATUS AND METHODS FOR MANUFACTURING SUCH CAGES

IT1196429B
(en)

1986-07-01
1988-11-16
Mediolanum Farmaceutici Srl

PROCESS FOR THE PREPARATION OF PYRID BENZOTIAZINS FOR ANTIBACTERIAL ACTIVITY AND THEIR SALTS WITH SULPHONIC ACIDS

IT1197841B
(en)

1986-10-14
1988-12-06
Mediolanum Farmaceutici Srl

PYRID-BENZOTHIAZINIC DERIVATIVES WITH ANTIBACTERIAL ACTIVITY AND LONG LIFE

IT1222833B
(en)

1987-10-06
1990-09-12
Mediolanum Farmaceutici Srl

PYROID BENZOTHIAZINIC DERIVATIVES EQUIPPED WITH HIGH ANTIBACTERIAL ACTIVITY AND HIGH TISSUE BIO AVAILABILITY

US4840525A
(en)

1987-12-09
1989-06-20
Unistrut International Corp.
Fastener restrainer for framing system

DE3906365A1
(en)

1988-07-15
1990-01-18
Bayer Ag

7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM

US5308843A
(en)

1990-09-11
1994-05-03
Sterling Drug Inc.
Method of inhibiting mammalian topoisomerase II and malignant cell growth in mammals, with substituted (S)-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4 ]-benzoxazine(and-benzothiazine)-6-carboxylic acids

IT1248011B
(en)

1991-06-07
1995-01-05
Mediolanum Farmaceutici Spa

PROCEDURE FOR THE PREPARATION OF 9-FLUORO-10- (4-METHYL-1-PIPERAZINYL) -7-OXO-2,3-DIHYDRO-7H-PYRID (1,2,3-DE) acid (1,4) BENZOTIADIN-6-CARBOXYL HYDROCHLORIDE.

US5532239A
(en)

1993-08-02
1996-07-02
Assistance Publique – Hopitaux De Paris
Therapeutic application of fluoroquinolone derivatives

IT1270834B
(en)

1993-10-27
1997-05-13
Archimica Spa

DISINFURO QUINOLICO

US6326391B1
(en)

1998-12-04
2001-12-04
Influx, Inc.
Inhibitors of multidrug transporters

US6262072B1
(en)

1999-10-12
2001-07-17
Yung Shin Pharmaceutical Industrial Co. Ltd.
Orally administered antimicrobial pharmaceutical formulations of ciprofloxacin

SE9904108D0
(en)

1999-11-15
1999-11-15
New Pharma Research Ab

New compounds

KR100440192B1
(en)

2001-11-22
2004-07-12
이수화학 주식회사
Method of preparing optical active quinolonecarboxylic acid derivatives

US6957105B2
(en)

2002-03-26
2005-10-18
Cardiac Pacemakers, Inc.
Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals

US20070196398A1
(en)

2006-02-17
2007-08-23
Murthy Yerramilli V S
Fluoroquinolone fatty acid salt compositions

US20070197548A1
(en)

2006-02-17
2007-08-23
Murthy Yerramilli V S
Fluoroquinolone compositions

US7973022B2
(en)

2006-02-17
2011-07-05
Idexx Laboratories, Inc.
Fluoroquinolone carboxylic acid salt compositions

WO2013076590A1
(en)

2011-11-23
2013-05-30
Oxygen Healthcare Research Pvt. Ltd
Benzothiazine compounds as h3 receptor ligands

DE102013101756A1
(en)

2012-11-30
2014-06-05
Hamberger Industriewerke Gmbh
Connector e.g. glueless connector, for e.g. floor element for flooring applications, has structural element moved to latch position in which locking lip of locking element is non-positively or positively locked in direction

DE102013108539A1
(en)

2013-08-07
2015-02-12
Hamberger Industriewerke Gmbh

Connection and locking element

DE102013108538A1
(en)

2013-08-07
2015-02-12
Hamberger Industriewerke Gmbh

Connection and locking element

DE102015106035A1
(en)

2014-07-31
2016-02-04
Hamberger Industriewerke Gmbh

Connection for plate-shaped components and spring

Family Cites Families (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPS57203085A
(en)

1981-06-09
1982-12-13
Dai Ichi Seiyaku Co Ltd
1,8-cyclic substituted quinoline derivative

JPS5976091A
(en)

1982-10-22
1984-04-28
Otsuka Pharmaceut Co Ltd
Pyrido (1,2,3-de)(1,4)benzothiazine derivative

1984

1984-02-24
IT
IT19790/84A
patent/IT1173374B/en
active
Protection Beyond IP Right Term

1985

1985-02-21
EP
EP85101881A
patent/EP0165375B1/en
not_active
Expired – Lifetime

1985-02-21
DE
DE8585101881T
patent/DE3580124D1/en
not_active
Expired – Fee Related

1985-02-21
AT
AT85101881T
patent/ATE57532T1/en
not_active
IP Right Cessation

1985-02-21
IE
IE432/85A
patent/IE57974B1/en
not_active
IP Right Cessation

1985-02-22
DK
DK81885A
patent/DK81885A/en
not_active
Application Discontinuation

1985-02-22
FI
FI850741A
patent/FI83327C/en
not_active
IP Right Cessation

1985-02-22
ZA
ZA851379A
patent/ZA851379B/en
unknown

1985-02-22
NO
NO850710A
patent/NO171163C/en
unknown

1985-02-22
PT
PT80003A
patent/PT80003B/en
not_active
IP Right Cessation

1985-02-22
CA
CA000474952A
patent/CA1340554C/en
not_active
Expired – Fee Related

1985-02-23
KR
KR8501180A
patent/KR880000024B1/en
not_active
IP Right Cessation

1985-02-23
ES
ES541170A
patent/ES8801923A1/en
not_active
Expired

1985-02-24
EG
EG115/85A
patent/EG17585A/en
active

1985-02-25
MX
MX013422A
patent/MX172473B/en
unknown

1985-02-25
MX
MX013420A
patent/MX172472B/en
unknown

1985-02-25
MX
MX013421A
patent/MX173934B/en
unknown

1985-02-25
JP
JP60036261A
patent/JPS60208987A/en
active
Granted

1985-02-25
MX
MX5776A
patent/MX162343A/en
unknown

1985-02-25
AU
AU39142/85A
patent/AU573780B2/en
not_active
Ceased

1985-02-25
NZ
NZ211224A
patent/NZ211224A/en
unknown

1985-02-25
PH
PH31907A
patent/PH22239A/en
unknown

1985-02-25
YU
YU290/85A
patent/YU43401B/en
unknown

1985-02-26
GR
GR850482A
patent/GR850482B/el
not_active
IP Right Cessation

1985-08-13
US
US06/765,154
patent/US4668784A/en
not_active
Expired – Lifetime

1986

1986-10-24
US
US06/922,712
patent/US4684647A/en
not_active
Expired – Lifetime

1987

1987-01-16
ES
ES557332A
patent/ES8802456A1/en
not_active
Expired

1987-01-16
ES
ES557331A
patent/ES8802455A1/en
not_active
Expired

1987-08-05
PH
PH35622A
patent/PH23882A/en
unknown

1989

1989-11-29
JP
JP1307826A
patent/JPH0327389A/en
active
Granted

1992

1992-06-26
MX
MX9203608A
patent/MX9203608A/en
unknown

Also Published As

Publication number
Publication date

JPH0327389A
(en)

1991-02-05

ZA851379B
(en)

1985-10-30

CA1340554C
(en)

1999-05-25

MX172473B
(en)

1993-12-17

ATE57532T1
(en)

1990-11-15

YU43401B
(en)

1989-06-30

AU573780B2
(en)

1988-06-23

FI850741A0
(en)

1985-02-22

US4668784A
(en)

1987-05-26

EP0165375A3
(en)

1986-10-08

EG17585A
(en)

1993-08-30

IE850432L
(en)

1985-08-24

DK81885A
(en)

1985-08-25

EP0165375B1
(en)

1990-10-17

FI850741L
(en)

1985-08-25

ES557331A0
(en)

1988-06-16

PH23882A
(en)

1989-12-18

ES8802455A1
(en)

1988-06-16

IE57974B1
(en)

1993-06-02

GR850482B
(en)

1985-06-26

PT80003A
(en)

1985-03-01

MX173934B
(en)

1994-04-11

FI83327C
(en)

1991-06-25

IT8419790D0
(en)

1984-02-24

ES8802456A1
(en)

1988-06-16

KR850006426A
(en)

1985-10-05

NO171163C
(en)

1993-02-03

ES541170A0
(en)

1988-03-01

MX162343A
(en)

1991-04-26

MX172472B
(en)

1993-12-17

NO850710L
(en)

1985-08-26

DK81885D0
(en)

1985-02-22

US4684647A
(en)

1987-08-04

PH22239A
(en)

1988-07-01

DE3580124D1
(en)

1990-11-22

ES557332A0
(en)

1988-06-16

FI83327B
(en)

1991-03-15

MX9203608A
(en)

1992-07-01

NZ211224A
(en)

1992-03-26

YU29085A
(en)

1987-12-31

JPH0259153B2
(en)

1990-12-11

NO171163B
(en)

1992-10-26

JPS60208987A
(en)

1985-10-21

JPH0413326B2
(en)

1992-03-09

PT80003B
(en)

1987-06-17

KR880000024B1
(en)

1988-02-15

EP0165375A2
(en)

1985-12-27

ES8801923A1
(en)

1988-03-01

IT1173374B
(en)

1987-06-24

Contact information