AU4015897A

AU4015897A – N-substututed indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action
– Google Patents

AU4015897A – N-substututed indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action
– Google Patents
N-substututed indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action

Info

Publication number
AU4015897A

AU4015897A
AU40158/97A
AU4015897A
AU4015897A
AU 4015897 A
AU4015897 A
AU 4015897A
AU 40158/97 A
AU40158/97 A
AU 40158/97A
AU 4015897 A
AU4015897 A
AU 4015897A
AU 4015897 A
AU4015897 A
AU 4015897A
Authority
AU
Australia
Prior art keywords
glyoxylamides
substututed
asthmatic
antiallergic
immunosuppressant
Prior art date
1996-09-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU40158/97A
Other versions

AU726521C
(en

AU726521B2
(en

Inventor
Kay Brune
Peter Emig
Bernhard Kutscher
Guillaume Le Baut
Cecilia Menciu
Stefan Szelenyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ziopharm Oncology Inc

Original Assignee
Ziopharm Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1996-09-06
Filing date
1997-08-16
Publication date
1998-03-26

1997-08-16
Application filed by Ziopharm Oncology Inc
filed
Critical
Ziopharm Oncology Inc

1998-03-26
Publication of AU4015897A
publication
Critical
patent/AU4015897A/en

1998-03-26
Publication of AU726521C
publication
Critical
patent/AU726521C/en

2000-11-09
Application granted
granted
Critical

2000-11-09
Publication of AU726521B2
publication
Critical
patent/AU726521B2/en

2007-10-04
Assigned to ZIOPHARM ONCOLOGY, INC.
reassignment
ZIOPHARM ONCOLOGY, INC.
Alteration of Name(s) in Register under S187
Assignors: ASTA MEDICA AKTIENGESELLSCHAFT

2017-08-16
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings

C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P11/00—Drugs for disorders of the respiratory system

A61P11/06—Antiasthmatics

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P17/00—Drugs for dermatological disorders

A61P17/06—Antipsoriatics

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P19/00—Drugs for skeletal disorders

A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A61P37/02—Immunomodulators

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A61P37/02—Immunomodulators

A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P37/00—Drugs for immunological or allergic disorders

A61P37/08—Antiallergic agents

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring

C07D209/04—Indoles; Hydrogenated indoles

C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings

C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom

C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

AU40158/97A
1996-09-06
1997-08-16
N-substututed indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action

Ceased

AU726521B2
(en)

Applications Claiming Priority (3)

Application Number
Priority Date
Filing Date
Title

DE19636150A

DE19636150A1
(en)

1996-09-06
1996-09-06

N-substituted indole-3-glyoxylamides with antiasthmatic, antiallergic and immunosuppressive / immunomodulating effects

DE19636150

1996-09-06

PCT/EP1997/004474

WO1998009946A1
(en)

1996-09-06
1997-08-16
N-substituted indol-3-glyoxylamid with antiasthmatic, antiallergic and immunosuppressive/immunomodulating effect

Publications (3)

Publication Number
Publication Date

AU4015897A
true

AU4015897A
(en)

1998-03-26

AU726521C

AU726521C
(en)

1998-03-26

AU726521B2

AU726521B2
(en)

2000-11-09

Family
ID=7804772
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU40158/97A
Ceased

AU726521B2
(en)

1996-09-06
1997-08-16
N-substututed indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action

Country Status (27)

Country
Link

US
(4)

US6008231A
(en)

EP
(1)

EP0931063B3
(en)

JP
(1)

JP3296437B2
(en)

KR
(1)

KR100516321B1
(en)

CN
(3)

CN100488948C
(en)

AR
(1)

AR008630A1
(en)

AT
(1)

ATE342889T1
(en)

AU
(1)

AU726521B2
(en)

BR
(1)

BR9712808B1
(en)

CA
(1)

CA2215013C
(en)

CZ
(1)

CZ302301B6
(en)

DE
(2)

DE19636150A1
(en)

DK
(1)

DK0931063T5
(en)

ES
(1)

ES2276433T7
(en)

HK
(3)

HK1021641A1
(en)

HU
(1)

HU227797B1
(en)

IL
(1)

IL127798A
(en)

NO
(2)

NO314725B3
(en)

NZ
(1)

NZ334476A
(en)

PT
(1)

PT931063E
(en)

RU
(1)

RU2237661C2
(en)

SK
(1)

SK285618B6
(en)

TR
(1)

TR199900469T2
(en)

TW
(1)

TW550256B
(en)

UA
(1)

UA60312C2
(en)

WO
(1)

WO1998009946A1
(en)

ZA
(1)

ZA977475B
(en)

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU748403B2
(en)

*

1998-04-28
2002-06-06
Elbion Ag
New hydroxyindoles, their use as phosphodiesterase 4 inhibitors and method for producing same

AU768510B2
(en)

*

1998-04-02
2003-12-18
Ziopharm Oncology, Inc.
Indolyl-3-glyoxylic acid derivatives with antitumoral activity

Families Citing this family (47)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE19636150A1
(en)

*

1996-09-06
1998-03-12
Asta Medica Ag

N-substituted indole-3-glyoxylamides with antiasthmatic, antiallergic and immunosuppressive / immunomodulating effects

AU774929B2
(en)

*

1998-03-31
2004-07-15
Institutes For Pharmaceutical Discovery, Llc, The
Substituted indolealkanoic acids

CZ302588B6
(en)

*

1998-04-02
2011-07-27
Ziopharm Oncology, Inc.
Use of N-substituted indole-3-gloxylamide for preparing a medicament

DE19946301A1
(en)

1998-04-02
2001-04-19
Asta Medica Ag
Antitumor agents and angiogenesis inhibitors having low neurotoxicity, comprise indole-3-glyoxylamide derivatives, are effective against resistant and metastasis-forming carcinomas

DE19917504A1
(en)

*

1999-04-17
2000-10-19
Dresden Arzneimittel
New hydroxy-indole derivatives, useful in treatment of degenerative joint disease, viral and parasitic infections, bronchial, dermatological, neurodegenerative and prostate disorders, etc.

DE19818964A1
(en)

*

1998-04-28
1999-11-04
Dresden Arzneimittel
New hydroxy-indole derivatives useful in treatment of degenerative joint disease, viral and parasitic infections, bronchial, dermatological, neurodegenerative and prostate disorders, etc.

AU777012B2
(en)

1999-08-21
2004-09-30
Takeda Gmbh
Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist

TWI269654B
(en)

*

1999-09-28
2007-01-01
Baxter Healthcare Sa
N-substituted indole-3-glyoxylamide compounds having anti-tumor action

DE19962300A1
(en)

*

1999-12-23
2001-06-28
Asta Medica Ag
New N-benzylindolyl glyoxylic acid derivatives are useful as antitumor agents

DE10022925A1
(en)

*

2000-05-11
2001-11-15
Basf Ag
New indole-carboxamide or azepino-indole derivatives and analogs, are poly-ADP ribose polymerase inhibitors useful e.g. for treating neurodegenerative disease, ischemia, epilepsy, tumors, sepsis or diabetes mellitus

DE10037310A1
(en)

2000-07-28
2002-02-07
Asta Medica Ag

New indole derivatives and their use as medicines

AU2002323474B2
(en)

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2001-09-13
2006-10-05
Synta Pharmaceuticals Corp
3-glyoxlylamideindoles for treating cancer

US6903104B2
(en)

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2001-12-06
2005-06-07
National Health Research Institutes
Indol-3-YL-2-oxoacetamide compounds and methods of use thereof

CA2493755A1
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2002-07-26
2004-02-05
The Institutes For Pharmaceutical Discovery, Llc
Substituted indolealkanoic acids derivative and formulations containing same for use in treatment of diabetic complications

NZ537947A
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*

2002-08-01
2006-11-30
Elbion Ag
Method for producing highly pure hydroxy indolyl glyoxylic acid amides

DE10253426B4
(en)

*

2002-11-15
2005-09-22
Elbion Ag

Novel hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and methods for their preparation

DE10318610A1
(en)

*

2003-04-24
2004-11-11
Elbion Ag

7-azaindoles and their use as therapeutic agents

DE10318609A1
(en)

*

2003-04-24
2004-11-11
Elbion Ag

5-hydroxyindoles with N-oxide groups and their use as therapeutic agents

DE10318611A1
(en)

2003-04-24
2004-11-11
Elbion Ag

4-, 6- or 7-hydroxyindoles with N-oxide groups and their use as therapeutic agents

US20050075364A1
(en)

*

2003-07-01
2005-04-07
Kap-Sun Yeung
Indole, azaindole and related heterocyclic N-substituted piperazine derivatives

CA2538820A1
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2003-09-11
2005-03-17
Kemia, Inc.
Cytokine inhibitors

EP2583678A3
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2004-06-24
2013-11-13
Novartis Vaccines and Diagnostics, Inc.
Small molecule immunopotentiators and assays for their detection

DE102004031538A1
(en)

*

2004-06-29
2006-02-09
Baxter International Inc., Deerfield
Presentation form (obtainable by dissolving indibulin in or with a highly concentrated organic acid), useful to orally administer poorly soluble active compound indibulin, comprises a poorly soluble active compound indibulin

ES2424255T3
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2004-11-08
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Baxter International Inc.

Particulate compositions of tubulin inhibitors

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2004-11-09
2006-05-11
Matiskella John D
Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione

US20060100209A1
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2004-11-09
2006-05-11
Chong-Hui Gu
Formulations of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione

US8604055B2
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2004-12-31
2013-12-10
Dr. Reddy’s Laboratories Ltd.
Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors

JP5096927B2
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2004-12-31
2012-12-12
レディ ユーエス セラピューティックス, インコーポレイテッド

Novel benzylamine derivatives as CETP inhibitors

JP2006247963A
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2005-03-09
2006-09-21
Oji Paper Co Ltd
Inkjet recording sheet

WO2006099256A2
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2005-03-11
2006-09-21
Vertex Pharmaceuticals Incorporated
Modulators of atp-binding cassette transporters

US7328672B2
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2005-04-29
2008-02-12
Tendik Development, Llc
Radial impulse engine, pump, and compressor systems, and associated methods of operation

US20060280787A1
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2005-06-14
2006-12-14
Baxter International Inc.
Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof

US7598380B2
(en)

*

2005-08-03
2009-10-06
Bristol-Myers Squibb Company
Method of preparation of azaindole derivatives

ITMI20051999A1
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*

2005-10-21
2007-04-22
Eratech S R L

INHALATION FORMULATIONS OF DRUGS IN DRY POWDER FOR ADMINISTRATION AS SUCH OR WITH NEBULIZER AND EQUIPPED WITH HIGH EROGABILITY RESPIRABILITY AND STABILITY

US7851476B2
(en)

*

2005-12-14
2010-12-14
Bristol-Myers Squibb Company
Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine

US7807671B2
(en)

2006-04-25
2010-10-05
Bristol-Myers Squibb Company
Diketo-piperazine and piperidine derivatives as antiviral agents

EA021461B1
(en)

2006-07-05
2015-06-30
Такеда Гмбх
Pharmaceutical composition and combination pharmaceutical containing hmg-coa reductase and phosphodiesterase 4 inhibitors and use thereof for the treatment of inflammatory pulmonary diseases

EP2610244A1
(en)

*

2006-08-07
2013-07-03
Ironwood Pharmaceuticals, Inc.
Indole compounds

JP2010509237A
(en)

*

2006-11-02
2010-03-25
アレテ セラピューティクス, インコーポレイテッド

Soluble epoxide hydrolase inhibitor

AU2007325797B2
(en)

*

2006-11-28
2014-03-13
Ziopharm Oncology, Inc.
Use of indolyl-3-glyoxylic acid derivatives including indibulin, alone or in combination with further agents for treating cancer

EP3791880A1
(en)

2009-04-29
2021-03-17
Amarin Pharmaceuticals Ireland Limited
Pharmaceutical compositions comprising epa

AR084433A1
(en)

2010-12-22
2013-05-15
Ironwood Pharmaceuticals Inc

FAAH INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

JP5964965B2
(en)

2011-08-18
2016-08-03
ドクター レディズ ラボラトリーズ リミテッド

Substituted heterocyclic amine compounds as cholesteryl ester transfer protein (CETP) inhibitors

WO2013046045A1
(en)

2011-09-27
2013-04-04
Dr. Reddy’s Laboratories, Ltd.
5 – benzylaminomethyl – 6 – aminopyrazolo [3, 4 -b] pyridine derivatives as cholesteryl ester -transfer protein (cetp) inhibitors useful for the treatment of atherosclerosis

EP3165224A1
(en)

2015-11-09
2017-05-10
Albert-Ludwigs-Universität Freiburg
Use of pde4 inhibitors for the prophylaxis and/or therapy of dyslipoproteinaemia and related disorders

WO2017089347A1
(en)

2015-11-25
2017-06-01
Inserm (Institut National De La Sante Et De La Recherche Medicale)
Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas

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(en)

*

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Navigation object traveling route reminding method and system

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(en)

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1955-04-11
1958-06-25
Upjohn Co
3-substituted indoles

GB944443A
(en)

*

1959-09-25
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*

1962-08-28
1966-05-11
Ici Ltd
Indole derivatives

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(en)

*

1964-02-28
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Merck & Co Inc
Indole derivatives

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Substituted aminoethyl indoles

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NOVEL PERHYDROISOINDOLE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

IL113210A
(en)

*

1994-04-01
2001-01-28
Lilly Co Eli
1H-indole-3- glyoxylamide spla2 inhibitors and pharmaceutical compositions containing them

DE19636150A1
(en)

*

1996-09-06
1998-03-12
Asta Medica Ag

N-substituted indole-3-glyoxylamides with antiasthmatic, antiallergic and immunosuppressive / immunomodulating effects

DE19946301A1
(en)

*

1998-04-02
2001-04-19
Asta Medica Ag
Antitumor agents and angiogenesis inhibitors having low neurotoxicity, comprise indole-3-glyoxylamide derivatives, are effective against resistant and metastasis-forming carcinomas

US7205299B2
(en)

*

2003-06-05
2007-04-17
Zentaris Gmbh
Indole derivatives having an apoptosis-inducing effect

1996

1996-09-06
DE
DE19636150A
patent/DE19636150A1/en
not_active
Ceased

1997

1997-08-16
PT
PT97937586T
patent/PT931063E/en
unknown

1997-08-16
CN
CNB021320616A
patent/CN100488948C/en
not_active
Expired – Fee Related

1997-08-16
CN
CN2008100087226A
patent/CN101219985B/en
not_active
Expired – Fee Related

1997-08-16
BR
BRPI9712808-2A
patent/BR9712808B1/en
not_active
IP Right Cessation

1997-08-16
DE
DE59712752T
patent/DE59712752D1/en
not_active
Expired – Lifetime

1997-08-16
UA
UA99041907A
patent/UA60312C2/en
unknown

1997-08-16
TR
TR1999/00469T
patent/TR199900469T2/en
unknown

1997-08-16
WO
PCT/EP1997/004474
patent/WO1998009946A1/en
active
IP Right Grant

1997-08-16
DK
DK97937586T
patent/DK0931063T5/en
active

1997-08-16
EP
EP97937586A
patent/EP0931063B3/en
not_active
Expired – Lifetime

1997-08-16
AT
AT97937586T
patent/ATE342889T1/en
active

1997-08-16
KR
KR10-1999-7001909A
patent/KR100516321B1/en
not_active
IP Right Cessation

1997-08-16
JP
JP51216798A
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1997-08-16
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1997-08-16
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1999-03-04
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HK00100629A
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2002-01-30
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2004-09-17
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Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU768510B2
(en)

*

1998-04-02
2003-12-18
Ziopharm Oncology, Inc.
Indolyl-3-glyoxylic acid derivatives with antitumoral activity

AU748403B2
(en)

*

1998-04-28
2002-06-06
Elbion Ag
New hydroxyindoles, their use as phosphodiesterase 4 inhibitors and method for producing same

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(en)

2002-07-02

UA60312C2
(en)

2003-10-15

RU2237661C2
(en)

2004-10-10

HK1123280A1
(en)

2009-06-12

US6919344B2
(en)

2005-07-19

ZA977475B
(en)

1998-02-19

IL127798A0
(en)

1999-10-28

NO991071D0
(en)

1999-03-04

HU9903741A3
(en)

2001-01-29

NO991071L
(en)

1999-03-04

ES2276433T3
(en)

2007-06-16

EP0931063B1
(en)

2006-10-18

WO1998009946A1
(en)

1998-03-12

HK1064379A1
(en)

2005-01-28

CN101219985B
(en)

2011-04-27

TR199900469T2
(en)

1999-05-21

NO314725B1
(en)

2003-05-12

NZ334476A
(en)

2000-05-26

CN1227542A
(en)

1999-09-01

BR9712808A
(en)

1999-11-23

ATE342889T1
(en)

2006-11-15

US20030207892A1
(en)

2003-11-06

HK1021641A1
(en)

2000-06-23

AU726521C
(en)

1998-03-26

CN100376554C
(en)

2008-03-26

IL127798A
(en)

2003-07-31

NO314725B3
(en)

2009-03-09

PT931063E
(en)

2007-02-28

CZ61699A3
(en)

1999-06-16

CA2215013C
(en)

2002-03-05

DE19636150A1
(en)

1998-03-12

HU9903741A2
(en)

2000-04-28

CN1496980A
(en)

2004-05-19

DE59712752D1
(en)

2006-11-30

KR20000068495A
(en)

2000-11-25

ES2276433T7
(en)

2009-11-05

CA2215013A1
(en)

1998-03-06

HU227797B1
(en)

2012-03-28

AU726521B2
(en)

2000-11-09

NO20030481L
(en)

1999-03-04

TW550256B
(en)

2003-09-01

DK0931063T3
(en)

2007-02-19

BR9712808B1
(en)

2009-05-05

CN101219985A
(en)

2008-07-16

AR008630A1
(en)

2000-02-09

NO20030481D0
(en)

2003-01-30

SK27199A3
(en)

1999-08-06

SK285618B6
(en)

2007-05-03

US20020161025A1
(en)

2002-10-31

EP0931063B3
(en)

2009-04-08

CN100488948C
(en)

2009-05-20

EP0931063A1
(en)

1999-07-28

KR100516321B1
(en)

2005-09-23

DK0931063T5
(en)

2010-01-11

US6344467B1
(en)

2002-02-05

US6008231A
(en)

1999-12-28

JP2000505098A
(en)

2000-04-25

CZ302301B6
(en)

2011-02-09

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Date
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2001-03-08
FGA
Letters patent sealed or granted (standard patent)

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