AU4422679A - Creation of Inventions and Patents with Artificial Intelligence

AU4422679A – Halogen substituted mercaptoacylamino acids
– Google Patents

AU4422679A – Halogen substituted mercaptoacylamino acids
– Google Patents
Halogen substituted mercaptoacylamino acids

Info

Publication number
AU4422679A

AU4422679A
AU44226/79A
AU4422679A
AU4422679A
AU 4422679 A
AU4422679 A
AU 4422679A
AU 44226/79 A
AU44226/79 A
AU 44226/79A
AU 4422679 A
AU4422679 A
AU 4422679A
AU 4422679 A
AU4422679 A
AU 4422679A
Authority
AU
Australia
Prior art keywords
halogen substituted
mercaptoacylamino acids
mercaptoacylamino
acids
halogen
Prior art date
1978-02-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU44226/79A
Other versions

AU518847B2
(en

Inventor
Miguel Angel Ondetti
Peter Whitney Sprague
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ER Squibb and Sons LLC

Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1978-02-21
Filing date
1979-02-14
Publication date
1979-08-30

1979-02-14
Application filed by ER Squibb and Sons LLC
filed
Critical
ER Squibb and Sons LLC

1979-08-30
Publication of AU4422679A
publication
Critical
patent/AU4422679A/en

1981-10-22
Application granted
granted
Critical

1981-10-22
Publication of AU518847B2
publication
Critical
patent/AU518847B2/en

1995-02-14
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members

C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C327/00—Thiocarboxylic acids

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms

C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members

C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

AU44226/79A
1978-02-21
1979-02-14
Halogen substituted mercaptoacylamino acids

Ceased

AU518847B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US87903278A

1978-02-21
1978-02-21

US879032

1986-06-26

Publications (2)

Publication Number
Publication Date

AU4422679A
true

AU4422679A
(en)

1979-08-30

AU518847B2

AU518847B2
(en)

1981-10-22

Family
ID=25373297
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU44226/79A
Ceased

AU518847B2
(en)

1978-02-21
1979-02-14
Halogen substituted mercaptoacylamino acids

Country Status (4)

Country
Link

US
(1)

US4154935A
(en)

AU
(1)

AU518847B2
(en)

BE
(1)

BE874345A
(en)

ZA
(1)

ZA79612B
(en)

Families Citing this family (83)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4241076A
(en)

1978-02-21
1980-12-23
E. R. Squibb & Sons, Inc.
Halogenated substituted mercaptoacylamino acids

US4316906A
(en)

1978-08-11
1982-02-23
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of substituted prolines

US4698355A
(en)

1979-08-14
1987-10-06
University Of Miami
Anti-hypertensive agents

US4690940A
(en)

1979-08-14
1987-09-01
University Of Miami
Anti-hypertensive agents

US4690939A
(en)

1979-08-14
1987-09-01
University Of Miami
Anti-hypertensive agents

US4690937A
(en)

1979-08-14
1987-09-01
University Of Miami
Anti-hypertensive agents

US4690938A
(en)

1979-08-14
1987-09-01
University Of Miami
Anti-hypertensive agents

US4698356A
(en)

1979-08-14
1987-10-06
University Of Miami
Anti-hypertensive agents

US4695577A
(en)

1979-08-14
1987-09-22
University Of Miami
Anti-hypertensive agents

ZA794723B
(en)

1978-09-11
1980-08-27
Univ Miami
Anti-hypertensive agents

US4225495A
(en)

1978-12-07
1980-09-30
E. R. Squibb & Sons, Inc.
Pyrrolo or pyrido [2,1-c][1,4] thiazines or thiazepines

US4311697A
(en)

1978-12-22
1982-01-19
E. R. Squibb & Sons, Inc.
Derivatives of mercaptoacyl prolines and pipecolic acids

US4410542A
(en)

1978-12-30
1983-10-18
Santen Pharmaceutical Co., Ltd.
Disulfide compounds

EP0017390A3
(en)

1979-03-23
1981-06-24
American Home Products Corporation
Bicyclic oxo-thiolactones, pharmaceutical compositions containing them, processes for their preparation and compounds useful as intermediates for their preparation

DE3063420D1
(en)

1979-03-26
1983-07-07
Takeda Chemical Industries Ltd
Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension

US4291040A
(en)

1979-10-22
1981-09-22
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines

US4356182A
(en)

1979-10-22
1982-10-26
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of 4-disubstituted prolines

US4284561A
(en)

1979-12-03
1981-08-18
E. R. Squibb & Sons, Inc.
Hydroxamic acid derivatives of mercaptoacyl amino acids

US4308392A
(en)

1979-12-03
1981-12-29
E. R. Squibb & Sons, Inc.
Hydroxamic acid derivatives of mercaptoacyl amino acids

US4330548A
(en)

1980-01-14
1982-05-18
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of keto substituted pipecolic acid

US4296113A
(en)

1980-01-14
1981-10-20
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of keto substituted proline and pipecolic acid

US4321392A
(en)

1980-02-06
1982-03-23
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of 4-oxazolidine-carboxylic acids

IE50839B1
(en)

1980-02-26
1986-07-23
Wyeth John & Brother Ltd
Novel processes for preparing proline derivatives and analogous compounds

US4734420A
(en)

1980-03-05
1988-03-29
University Of Miami
Anti-hypertensive agents

US4692458A
(en)

1980-03-05
1987-09-08
University Of Miami
Anti-hypertensive agents

US4690936A
(en)

1980-03-05
1987-09-01
University Of Miami
Anti-hypertensive agents

SE431331B
(en)

1980-03-21
1984-01-30
Squibb & Sons Inc

NEW THERAPEUTICALLY ACTIVE SULFUR CONTAINING N-ACYLATED DERIVATIVES OF 4-OXO-L-PROLINE

US4350704A
(en)

1980-10-06
1982-09-21
Warner-Lambert Company
Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids

US4284624A
(en)

1980-05-02
1981-08-18
E. R. Squibb & Sons, Inc.
Mixed disulfides

US4578474A
(en)

1980-06-23
1986-03-25
E. R. Squibb & Sons, Inc.
Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids

US4390695A
(en)

1980-06-23
1983-06-28
E. R. Squibb & Sons, Inc.
Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids

US4310461A
(en)

1980-06-23
1982-01-12
E. R. Squibb & Sons, Inc.
Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids

US4296033A
(en)

1980-07-23
1981-10-20
E. R. Squibb & Sons, Inc.
4-Azido-1-mercaptoacyl proline

US4316905A
(en)

1980-07-01
1982-02-23
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of various 4-substituted prolines

US4308388A
(en)

1980-07-23
1981-12-29
E. R. Squibb & Sons, Inc.
4-Azido-1-mercaptoacyl pipecolic acid

US4332726A
(en)

1980-08-25
1982-06-01
E. R. Squibb & Sons, Inc.
Purification of mercaptoacyl amino acids

US4307110A
(en)

1980-09-12
1981-12-22
E. R. Squibb & Sons, Inc.
Mercaptoacyl derivatives of 3-substituted proline derivatives

US4344949A
(en)

1980-10-03
1982-08-17
Warner-Lambert Company
Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids

US4311705A
(en)

1980-10-06
1982-01-19
E. R. Squibb & Sons, Inc.
Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines

US4312809A
(en)

1980-10-31
1982-01-26
E. R. Squibb & Sons, Inc.
Lactam derivatives of mercaptoacylamino acids

US4313948A
(en)

1980-11-20
1982-02-02
E. R. Squibb & Sons, Inc.
Hypotensive imidazole substituted mercapto-1-oxopropyl-L-prolines

US4321383A
(en)

1980-11-24
1982-03-23
E. R. Squibb & Sons, Inc.
Heterobicyclo intermediates

US4462943A
(en)

1980-11-24
1984-07-31
E. R. Squibb & Sons, Inc.
Carboxyalkyl amino acid derivatives of various substituted prolines

US4303662A
(en)

1980-11-24
1981-12-01
E. R. Squibb & Sons, Inc.
Carboxyacyl, mercapto and acylmercapto derivatives of heterobicyclo compounds

US4337201A
(en)

1980-12-04
1982-06-29
E. R. Squibb & Sons, Inc.
Phosphinylalkanoyl substituted prolines

US4384123A
(en)

1980-12-04
1983-05-17
E. R. Squibb & Sons, Inc.
Phosphinylalkanoyl substituted prolines

US4456761A
(en)

1981-02-02
1984-06-26
E. R. Squibb & Sons, Inc.
4-Substituted dehydroprolines

US4499287A
(en)

1981-02-02
1985-02-12
E. R. Squibb & Sons, Inc.
Certain-4-hydroxy-proline derivatives

US4532342A
(en)

1981-02-20
1985-07-30
Warner-Lambert Company
N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids

US4374131A
(en)

1981-04-27
1983-02-15
E. R. Squibb & Sons, Inc.
Amino and substituted amino phosphinyl-alkanoyl compounds

US4416831A
(en)

1981-04-27
1983-11-22
E. R. Squibb & Sons, Inc.
Amino and substituted amino phosphinylalkanoyl compounds

US4381297A
(en)

1981-05-04
1983-04-26
E. R. Squibb & Sons, Inc.
Substituted carbonyl phosphinyl-alkanoyl compounds

US4416833A
(en)

1981-05-04
1983-11-22
E. R. Squibb & Sons, Inc.
Substituted carbonyl phosphinyl-alkanoyl compounds

US4497953A
(en)

1981-06-01
1985-02-05
E. R. Squibb & Sons, Inc.
Imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids

US4432971A
(en)

1981-08-03
1984-02-21
E. R. Squibb & Sons, Inc.
Phosphonamidate compounds

US4503043A
(en)

1981-12-07
1985-03-05
Warner-Lambert Company
Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acids

US4555506A
(en)

1981-12-24
1985-11-26
E. R. Squibb & Sons, Inc.
Phosphorus containing compounds and use as hypotensives

US4560680A
(en)

1982-03-15
1985-12-24
E. R. Squibb & Sons, Inc.
Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors

US4452791A
(en)

1982-03-15
1984-06-05
E. R. Squibb & Sons, Inc.
Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors

US4448772A
(en)

1982-04-22
1984-05-15
E. R. Squibb & Sons, Inc.
Phosphinylmethylaminocarbonyl imino acid compounds useful for treating hypertension

US4560681A
(en)

1982-04-22
1985-12-24
E. R. Squibb & Sons, Inc.
Phosphinylmethylaminocarbonyl imino acid compounds useful for treating hypertension

US4616005A
(en)

1982-06-23
1986-10-07
E. R. Squibb & Sons, Inc.
Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives

US4703043A
(en)

1982-06-23
1987-10-27
E. R. Squibb & Sons, Inc.
Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive

US4452790A
(en)

1982-06-23
1984-06-05
E. R. Squibb & Sons, Inc.
Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives

US4567166A
(en)

1982-07-14
1986-01-28
E. R. Squibb & Sons, Inc.
Amino and substituted amino phosphinylalkanoyl compounds useful for treating hypertension

US4736066A
(en)

1982-07-19
1988-04-05
E. R. Squibb & Sons, Inc.
Intermediate for substituted peptide compounds

US4470973A
(en)

1982-07-19
1984-09-11
E. R. Squibb & Sons, Inc.
Substituted peptide compounds

US4621092A
(en)

1982-07-22
1986-11-04
E. R. Squibb & Sons, Inc.
Substituted proline compounds, composition and method of use

US4623729A
(en)

1982-07-22
1986-11-18
E. R. Squibb & Sons, Inc.
Acylalkylaminocarbonyl substituted amino and imino acid compounds

US4742067A
(en)

1982-07-22
1988-05-03
E. R. Squibb & Sons, Inc.
Acylalkylaminocarbonyl substituted amino and imino acid compounds

US4404282A
(en)

1982-08-19
1983-09-13
Eli Lilly And Company
Process for enzyme inhibitor

US4508901A
(en)

1982-08-19
1985-04-02
Eli Lilly And Company
Quiuolizine and indolizine enzyme inhibitors

US4404281A
(en)

1982-08-19
1983-09-13
Eli Lilly And Company
Process for enzyme inhibitors

US4524212A
(en)

1982-09-27
1985-06-18
E. R. Squibb & Sons, Inc.
Acyloxyketone substituted imino and amino acids

US4499079A
(en)

1982-11-18
1985-02-12
E. R. Squibb & Sons, Inc.
Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides

US4456595A
(en)

1982-12-06
1984-06-26
E. R. Squibb & Sons, Inc.
Carboxy and substituted carboxy aroly peptides

US4514391A
(en)

1983-07-21
1985-04-30
E. R. Squibb & Sons, Inc.
Hydroxy substituted peptide compounds

US4675408A
(en)

1983-08-01
1987-06-23
Eli Lilly And Company
Octahydroindolizinepropanoic acids and related compounds as enzyme inhibitors

US4594431A
(en)

1983-08-01
1986-06-10
Eli Lilly Company
Octahydroindolizinepropanoic acids and related compounds as enzyme inhibitors

US5476791A
(en)

1984-08-16
1995-12-19
Mitsubishi Rayon Company, Limited
Process for producing optically active carboxylic acid amide

AU632596B2
(en)

1989-08-21
1993-01-07
E.R. Squibb & Sons, Inc.
Phosphonate substituted amino or imino acids useful as antihypertensives

IT1301993B1
(en)

1998-08-04
2000-07-20
Menarini Ricerche Spa

PROCESS FOR THE PREPARATION OF ZOFENOPRIL CALCIUM SALT.

US20070086958A1
(en)

2005-10-14
2007-04-19
Medafor, Incorporated
Formation of medically useful gels comprising microporous particles and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4105776A
(en)

1976-06-21
1978-08-08
E. R. Squibb & Sons, Inc.
Proline derivatives and related compounds

US4046889A
(en)

1976-02-13
1977-09-06
E. R. Squibb & Sons, Inc.
Azetidine-2-carboxylic acid derivatives

US4052511A
(en)

1976-02-13
1977-10-04
E. R. Squibb & Sons, Inc.
Carboxyacylproline derivatives

US4091024A
(en)

1976-12-03
1978-05-23
E. R. Squibb & Sons, Inc.
Pyrrolidine and piperidine-2-carboxylic acid derivatives

US4070361A
(en)

1977-04-21
1978-01-24
E. R. Squibb & Sons, Inc.
Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof

1978

1978-09-01
US
US05/939,147
patent/US4154935A/en
not_active
Expired – Lifetime

1979

1979-02-14
AU
AU44226/79A
patent/AU518847B2/en
not_active
Ceased

1979-02-21
BE
BE0/193609A
patent/BE874345A/en
not_active
IP Right Cessation

1979-12-02
ZA
ZA79612A
patent/ZA79612B/en
unknown

Also Published As

Publication number
Publication date

AU518847B2
(en)

1981-10-22

US4154935A
(en)

1979-05-15

ZA79612B
(en)

1980-05-28

BE874345A
(en)

1979-08-21

Contact information