AU510169B2

AU510169B2 – Arylmalonamido-1-oxadethiacephalosporins
– Google Patents

AU510169B2 – Arylmalonamido-1-oxadethiacephalosporins
– Google Patents
Arylmalonamido-1-oxadethiacephalosporins

Info

Publication number
AU510169B2

AU510169B2
AU23508/77A
AU2350877A
AU510169B2
AU 510169 B2
AU510169 B2
AU 510169B2
AU 23508/77 A
AU23508/77 A
AU 23508/77A
AU 2350877 A
AU2350877 A
AU 2350877A
AU 510169 B2
AU510169 B2
AU 510169B2
Authority
AU
Australia
Prior art keywords
arylmalonamido
oxadethiacephalosporins
Prior art date
1976-03-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
AU23508/77A
Other versions

AU2350877A
(en

Inventor
Wataru Nagata
Masayuki Narisada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Shionogi and Co Ltd

Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1976-03-25
Filing date
1977-03-22
Publication date
1980-06-12

1976-03-25
Priority claimed from JP3340176A
external-priority
patent/JPS52122386A/en

1976-04-30
Priority claimed from JP5029576A
external-priority
patent/JPS52133997A/en

1977-03-22
Application filed by Shionogi and Co Ltd
filed
Critical
Shionogi and Co Ltd

1978-09-28
Publication of AU2350877A
publication
Critical
patent/AU2350877A/en

1980-06-12
Application granted
granted
Critical

1980-06-12
Publication of AU510169B2
publication
Critical
patent/AU510169B2/en

1993-03-22
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

C07D498/04—Ortho-condensed systems

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

AU23508/77A
1976-03-25
1977-03-22
Arylmalonamido-1-oxadethiacephalosporins

Expired

AU510169B2
(en)

Applications Claiming Priority (6)

Application Number
Priority Date
Filing Date
Title

JP3340176A

JPS52122386A
(en)

1976-03-25
1976-03-25
Cephalosporin analogous compounds as antibacterials

JP19760033401

1976-04-01

JP5029576A

JPS52133997A
(en)

1976-04-30
1976-04-30
Cephalosporin antibiotics

JP19760050295

1976-04-30

AU53625/79A

AU528617B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU57286/80A

AU531661B2
(en)

1976-03-25
1980-04-09
1-oxadethia-cephalosporins

Related Child Applications (3)

Application Number
Title
Priority Date
Filing Date

AU53625/79A
Division

AU528617B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU53624/79A
Division

AU527733B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU57286/80A
Division

AU531661B2
(en)

1976-03-25
1980-04-09
1-oxadethia-cephalosporins

Publications (2)

Publication Number
Publication Date

AU2350877A

AU2350877A
(en)

1978-09-28

AU510169B2
true

AU510169B2
(en)

1980-06-12

Family
ID=27423456
Family Applications (4)

Application Number
Title
Priority Date
Filing Date

AU23508/77A
Expired

AU510169B2
(en)

1976-03-25
1977-03-22
Arylmalonamido-1-oxadethiacephalosporins

AU53625/79A
Expired

AU528617B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU53624/79A
Expired

AU527733B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU57286/80A
Expired

AU531661B2
(en)

1976-03-25
1980-04-09
1-oxadethia-cephalosporins

Family Applications After (3)

Application Number
Title
Priority Date
Filing Date

AU53625/79A
Expired

AU528617B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU53624/79A
Expired

AU527733B2
(en)

1976-03-25
1979-12-07
1-oxadethia-cephalosporin antibiotics

AU57286/80A
Expired

AU531661B2
(en)

1976-03-25
1980-04-09
1-oxadethia-cephalosporins

Country Status (9)

Country
Link

US
(2)

US4138486A
(en)

AT
(1)

AT353959B
(en)

AU
(4)

AU510169B2
(en)

BE
(1)

BE852912A
(en)

CA
(1)

CA1085392A
(en)

CH
(1)

CH629208A5
(en)

FR
(1)

FR2345452A1
(en)

GB
(1)

GB1547351A
(en)

NL
(1)

NL176074C
(en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

CA1085392A
(en)

*

1976-03-25
1980-09-09
Masayuki Narisada
Arylmalonamido-1-oxadethiacephalosporins

US4180571A
(en)

*

1976-03-25
1979-12-25
Shionogi & Co., Ltd.
Arylmalonamido-1-oxadethiacephalosporins

US4478997A
(en)

*

1977-02-15
1984-10-23
Shionogi & Co., Ltd.
1-Oxadethiacepham compounds

GB1557552A
(en)

*

1977-02-15
1979-12-12
Shionogi & Co
1 oxadethiacepham compounds

US4443598A
(en)

*

1977-02-15
1984-04-17
Shionogi & Co., Ltd.
1-Oxadethiacepham compounds

CA1100962A
(en)

*

1977-04-28
1981-05-12
Yoshio Hamashima
Haloarylmalonamidooxacephalosporins

JPS5419990A
(en)

*

1977-07-14
1979-02-15
Shionogi & Co Ltd
Dihydrotriazinylthioxacephalosporin

JPS609718B2
(en)

*

1977-08-25
1985-03-12
塩野義製薬株式会社

Thiadiazolylthiosephalosporin related antibiotics

US4259485A
(en)

*

1979-04-24
1981-03-31
Eli Lilly And Company
Crystallization process

US4252953A
(en)

*

1979-05-01
1981-02-24
Eli Lilly And Company
Antibiotic crystalline epimer

JPS5690088A
(en)

*

1979-11-02
1981-07-21
Meiji Seika Kaisha Ltd
Novel cephalosporin analog compound

JPS56103185A
(en)

*

1980-01-22
1981-08-18
Shionogi & Co Ltd
Malonamidoxa-dethia-cephem compound

US4452778A
(en)

*

1980-03-31
1984-06-05
Eli Lilly And Company
Synergistic antibacterial compositions and method of treatment of infections caused by multiple antibiotic-resistant organisms

US4301282A
(en)

*

1980-09-17
1981-11-17
Eli Lilly And Company
1-Oxa-β-lactam antibiotics

US4304774A
(en)

*

1980-09-17
1981-12-08
Eli Lilly And Company
Bis-tetrazolmethyl substituted β-lactam antibiotics

US4368156A
(en)

*

1981-03-09
1983-01-11
Eli Lilly And Company
Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones

DE3269313D1
(en)

*

1981-05-14
1986-04-03
Beecham Group Plc
Process for the preparation of an enantiomer of a beta-lactam derivative

JPS5857360A
(en)

*

1981-10-01
1983-04-05
Ajinomoto Co Inc
Azetidinone derivative

US4391975A
(en)

*

1981-12-15
1983-07-05
Queen’s University At Kingston
Process for 1-oxacephem derivatives

US4594247A
(en)

*

1981-12-21
1986-06-10
Eli Lilly And Company
Synergistic antibacterial compositions and method of treatment of infections caused by multiple antibiotic-resistant organisms

US4552763A
(en)

*

1981-12-21
1985-11-12
Eli Lilly And Company
Synergistic antibacterial compositions and method of treatment of infections caused by multiple antibiotic-resistant organisms

JPS597193A
(en)

*

1982-07-02
1984-01-14
Shionogi & Co Ltd
Isomerization of malonylmethyl group

US4472576A
(en)

*

1982-12-03
1984-09-18
Merck & Co., Inc.
Processes for the production of antibiotic 1-oxadethiacephalosporins

JPS59152385A
(en)

*

1983-02-17
1984-08-31
Shionogi & Co Ltd
Hydroxamate-type cephalosporin derivative

SE8301182D0
(en)

*

1983-03-04
1983-03-04
Haessle Ab

NOVEL COMPOUNDS

JPS60123490A
(en)

*

1983-12-07
1985-07-02
Shionogi & Co Ltd
Malonyloxacephem carboxylic acid derivative

SK13897A3
(en)

1996-02-06
1998-05-06
Pliva Pharm & Chem Works
3-bromo- and 3,3-dibromo-4-oxo-1-azetidines, method for preparation thereof and their use

US6426342B2
(en)

*

1999-08-16
2002-07-30
Revaax Pharmaceuticals, Llc
Use of β-lactamase inhibitors as neuroprotectants

EP1206261B1
(en)

1999-08-16
2006-03-08
Revaax Pharmaceuticals LLC
Pharmaceutical compositions comprising clavulanic acid or derivative thereof for the treatment of behavioral diseases

US6489319B2
(en)

*

1999-08-16
2002-12-03
Revaax Pharmaceuticals, Llc
Neurotherapeutic use of carboxypeptidase inhibitors

KR20050083971A
(en)

*

2002-11-22
2005-08-26
더 존스 홉킨스 유니버시티
Target for therapy of cognitive impairment

KR20120012823A
(en)

*

2009-04-29
2012-02-10
렉산 파마슈티컬스, 인코포레이티드
Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders

CN102260280A
(en)

*

2010-05-28
2011-11-30
上海医药工业研究院
Preparation method of latamoxef disodium

CN102603784B
(en)

*

2012-04-06
2014-12-31
浙江惠迪森药业有限公司
Latamoxef aluminium chloride (stannum)-anisole complex, as well as preparation method and application thereof

CN102827191B
(en)

*

2012-09-24
2015-03-11
浙江东邦药业有限公司
Method for preparing oxygen cephalosporin compound

CN107383066A
(en)

*

2017-07-31
2017-11-24
山西千岫制药有限公司
A kind of method of latamoxef acid deprotection base

KR102115644B1
(en)

*

2017-09-13
2020-05-27
주식회사 동도물산
Method of manufacturing 7α-alkoxy oxacephem intermediate compound

Family Cites Families (11)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE1914366U
(en)

1965-01-08
1965-04-22
Otto Liebmann Fa

PROTECTIVE COVER FOR CIGARETTE BOXES OR PACKAGES.

US3769277A
(en)

*

1970-01-23
1973-10-30
Glaxo Lab Ltd
Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group

US3728342A
(en)

*

1970-12-03
1973-04-17
Lilly Co Eli
3-acyloxymethyl cephalosporins and method of preparation

US3795672A
(en)

*

1971-06-09
1974-03-05
Lilly Co Eli
Process for the preparation of delta2-cephem-4-carboxylic acid esters

NL7314706A
(en)

1972-11-06
1974-05-08

NL178005C
(en)

1972-11-06
1986-01-02
Merck & Co Inc

METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION WITH ANTIBACTERIAL ACTION, AND METHOD FOR PREPARING A CEPHALOSPORINE ANTIBIOTIC.

GB1510794A
(en)

1974-08-06
1978-05-17
Univ Kingston
1-oxacephems and intermediates therefor

US4011216A
(en)

*

1975-04-11
1977-03-08
Bristol-Myers Company
Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents

US4013648A
(en)

*

1975-07-23
1977-03-22
Bristol-Myers Company
Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents

CA1085392A
(en)

*

1976-03-25
1980-09-09
Masayuki Narisada
Arylmalonamido-1-oxadethiacephalosporins

US4180571A
(en)

*

1976-03-25
1979-12-25
Shionogi & Co., Ltd.
Arylmalonamido-1-oxadethiacephalosporins

1977

1977-03-18
CA
CA274,261A
patent/CA1085392A/en
not_active
Expired

1977-03-22
US
US05/780,183
patent/US4138486A/en
not_active
Expired – Lifetime

1977-03-22
AU
AU23508/77A
patent/AU510169B2/en
not_active
Expired

1977-03-23
GB
GB12326/77A
patent/GB1547351A/en
not_active
Expired

1977-03-24
AT
AT205777A
patent/AT353959B/en
not_active
IP Right Cessation

1977-03-25
BE
BE176149A
patent/BE852912A/en
not_active
IP Right Cessation

1977-03-25
CH
CH383177A
patent/CH629208A5/en
not_active
IP Right Cessation

1977-03-25
NL
NLAANVRAGE7703282,A
patent/NL176074C/en
not_active
IP Right Cessation

1977-03-25
FR
FR7709107A
patent/FR2345452A1/en
active
Granted

1979

1979-12-07
AU
AU53625/79A
patent/AU528617B2/en
not_active
Expired

1979-12-07
AU
AU53624/79A
patent/AU527733B2/en
not_active
Expired

1980

1980-04-09
AU
AU57286/80A
patent/AU531661B2/en
not_active
Expired

1980-06-05
US
US06/156,872
patent/US4323567A/en
not_active
Expired – Lifetime

Also Published As

Publication number
Publication date

US4323567A
(en)

1982-04-06

GB1547351A
(en)

1979-06-13

NL176074C
(en)

1985-02-18

AU528617B2
(en)

1983-05-05

AU2350877A
(en)

1978-09-28

AT353959B
(en)

1979-12-10

FR2345452A1
(en)

1977-10-21

US4138486A
(en)

1979-02-06

NL176074B
(en)

1984-09-17

CA1085392A
(en)

1980-09-09

AU5362479A
(en)

1980-05-01

BE852912A
(en)

1977-09-26

AU531661B2
(en)

1983-09-01

ATA205777A
(en)

1979-05-15

FR2345452B1
(en)

1980-07-25

AU5728680A
(en)

1980-06-19

NL7703282A
(en)

1977-09-27

CH629208A5
(en)

1982-04-15

AU5362579A
(en)

1980-05-01

AU527733B2
(en)

1983-03-17

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